Published in J Neurosci on May 16, 2007
Balancing structure and function at hippocampal dendritic spines. Annu Rev Neurosci (2008) 4.38
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Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol (2009) 2.21
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Spine expansion and stabilization associated with long-term potentiation. J Neurosci (2008) 1.91
Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. J Neurosci (2009) 1.83
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Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors. J Neurosci (2010) 1.62
Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone. J Neurosci (2008) 1.60
Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. J Neurosci (2009) 1.52
Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation. Neuron (2010) 1.49
Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I. J Neurosci (2010) 1.49
Short-term modern life-like stress exacerbates Aβ-pathology and synapse loss in 3xTg-AD mice. J Neurochem (2015) 1.47
Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling. Proc Natl Acad Sci U S A (2010) 1.43
Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice. Alzheimers Dement (2009) 1.36
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat Neurosci (2013) 1.36
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Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation. J Neurosci (2010) 1.33
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Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry (2010) 1.27
17-Beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activation. Proc Natl Acad Sci U S A (2009) 1.24
Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. J Neurosci (2010) 1.22
Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning. Proc Natl Acad Sci U S A (2012) 1.22
Rapid estrogen signaling in the brain: implications for the fine-tuning of neuronal circuitry. J Neurosci (2011) 1.17
Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci (2010) 1.12
Organization of the Arp2/3 complex in hippocampal spines. J Neurosci (2008) 1.09
Learning induces neurotrophin signaling at hippocampal synapses. Proc Natl Acad Sci U S A (2010) 1.07
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice. Brain Res (2010) 1.05
Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation. J Neurosci (2012) 1.02
Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia. Biol Psychiatry (2012) 1.01
Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons. J Biol Chem (2011) 1.01
Impairment of synaptic plasticity by the stress mediator CRH involves selective destruction of thin dendritic spines via RhoA signaling. Mol Psychiatry (2012) 1.00
Differences between synaptic plasticity thresholds result in new timing rules for maximizing long-term potentiation. Neuropharmacology (2012) 1.00
Plasticity of dendritic spines: subcompartmentalization of signaling. Annu Rev Physiol (2013) 0.99
Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines. Open Neurosci J (2009) 0.99
A molecular brake controls the magnitude of long-term potentiation. Nat Commun (2014) 0.97
NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH. J Neurosci (2013) 0.97
Inositol 1,4,5-trisphosphate 3-kinase a functions as a scaffold for synaptic Rac signaling. J Neurosci (2009) 0.96
Impaired fear response in mice lacking GIT1. Neurosci Lett (2009) 0.96
LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. J Neurosci (2012) 0.96
BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats. Neurobiol Aging (2010) 0.95
BDNF signaling during learning is regionally differentiated within hippocampus. J Neurosci (2010) 0.95
Actin Out: Regulation of the Synaptic Cytoskeleton. J Biol Chem (2015) 0.94
Estrogen promotes learning-related plasticity by modifying the synaptic cytoskeleton. Neuroscience (2012) 0.94
ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol (2015) 0.93
Activity-dependent dendritic spine shrinkage and growth involve downregulation of cofilin via distinct mechanisms. PLoS One (2014) 0.93
Ampakines cause sustained increases in brain-derived neurotrophic factor signaling at excitatory synapses without changes in AMPA receptor subunit expression. Neuroscience (2008) 0.92
Examining form and function of dendritic spines. Neural Plast (2012) 0.92
Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease. J Alzheimers Dis (2012) 0.91
Glucocorticoid receptors are localized to dendritic spines and influence local actin signaling. Mol Neurobiol (2012) 0.91
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PKMζ is necessary and sufficient for synaptic clustering of PSD-95. Hippocampus (2011) 0.90
Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PLoS One (2010) 0.89
Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci (2015) 0.89
Synaptic abnormalities in the infralimbic cortex of a model of congenital depression. J Neurosci (2013) 0.89
Microdomains in forebrain spines: an ultrastructural perspective. Mol Neurobiol (2012) 0.89
Multiple cellular cascades participate in long-term potentiation and in hippocampus-dependent learning. Brain Res (2014) 0.89
Pharmacological enhancement of memory or cognition in normal subjects. Front Syst Neurosci (2014) 0.87
Mechanism based approaches for rescuing and enhancing cognition. Front Neurosci (2013) 0.87
Structural plasticity: mechanisms and contribution to developmental psychiatric disorders. Front Neuroanat (2014) 0.87
Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons. Neuron (2014) 0.87
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. Elife (2016) 0.85
Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress. Mol Psychiatry (2014) 0.85
Structural plasticity of spines at giant mossy fiber synapses. Front Neural Circuits (2012) 0.85
Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration. Trends Neurosci (2016) 0.85
Stabilizing dendritic structure as a novel therapeutic approach for epilepsy. Expert Rev Neurother (2008) 0.84
Learning and memory: an emergent property of cell motility. Neurobiol Learn Mem (2013) 0.84
Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl. Mol Biol Cell (2014) 0.83
Altered expression of neuroplasticity-related genes in the brain of depressed suicides. Neuroscience (2015) 0.83
Wip1 phosphatase positively modulates dendritic spine morphology and memory processes through the p38MAPK signaling pathway. Cell Adh Migr (2012) 0.83
Distinct regional and subcellular localization of the actin-binding protein filamin A in the mature rat brain. J Comp Neurol (2012) 0.82
A role for α-adducin (ADD-1) in nematode and human memory. EMBO J (2012) 0.82
Fine structure of synapses on dendritic spines. Front Neuroanat (2014) 0.80
A map of LTP-related synaptic changes in dorsal hippocampus following unsupervised learning. J Neurosci (2014) 0.80
Rapid effects of oestrogen on synaptic plasticity: interactions with actin and its signalling proteins. J Neuroendocrinol (2013) 0.80
Dendritic spine plasticity as an underlying mechanism of neuropathic pain: commentary on Tan et al. Exp Neurol (2011) 0.79
TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses. Bioarchitecture (2011) 0.79
Dendritic spine remodeling following early and late Rac1 inhibition after spinal cord injury: evidence for a pain biomarker. J Neurophysiol (2016) 0.78
Activation of α7 nicotinic acetylcholine receptors protects potentiated synapses from depotentiation during theta pattern stimulation in the hippocampal CA1 region of rats. Neuropharmacology (2016) 0.77
Synaptic Efficacy as a Function of Ionotropic Receptor Distribution: A Computational Study. PLoS One (2015) 0.77
Neuronal profilins in health and disease: Relevance for spine plasticity and Fragile X syndrome. Proc Natl Acad Sci U S A (2016) 0.77
Hirano body expression impairs spatial working memory in a novel mouse model. Acta Neuropathol Commun (2014) 0.76
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ (2015) 0.76
Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex. Proc Natl Acad Sci U S A (2016) 0.76
Protein kinase D promotes plasticity-induced F-actin stabilization in dendritic spines and regulates memory formation. J Cell Biol (2015) 0.76
Capture of activity-induced ultrastructural changes at synapses by high-pressure freezing of brain tissue. Nat Protoc (2014) 0.76
Overexpression of Isoforms of Nitric Oxide Synthase 1 Adaptor Protein, Encoded by a Risk Gene for Schizophrenia, Alters Actin Dynamics and Synaptic Function. Front Cell Neurosci (2016) 0.76
Light exposure before learning improves memory consolidation at night. Sci Rep (2015) 0.76
RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction. Cell Death Dis (2015) 0.76
The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis. Mol Cell Neurosci (2016) 0.76
CD44 - a novel synaptic cell adhesion molecule regulating structural and functional plasticity of dendritic spines. Mol Biol Cell (2016) 0.76
The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila. Mol Cell Neurosci (2015) 0.75
Myosin IIb-dependent Regulation of Actin Dynamics Is Required for N-Methyl-d-aspartate Receptor Trafficking during Synaptic Plasticity. J Biol Chem (2015) 0.75
The phospholipid-binding protein SESTD1 negatively regulates dendritic spine density by interfering with Rac1-Trio8 signaling pathway. Sci Rep (2015) 0.75
Deletion of KIBRA, protein expressed in kidney and brain, increases filopodial-like long dendritic spines in neocortical and hippocampal neurons in vivo and in vitro. Front Neuroanat (2015) 0.75
Dendritic spine dysgenesis in superficial dorsal horn sensory neurons after spinal cord injury. Mol Pain (2017) 0.75
Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus. J Neurosci (2007) 2.39
Different Rho GTPase-dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation. J Cell Biol (2009) 2.25
Integrin-driven actin polymerization consolidates long-term potentiation. Proc Natl Acad Sci U S A (2006) 1.99
Mechanisms of late-onset cognitive decline after early-life stress. J Neurosci (2005) 1.98
Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain. J Comp Neurol (2007) 1.95
Brain-derived neurotrophic factor rescues synaptic plasticity in a mouse model of fragile X syndrome. J Neurosci (2007) 1.91
Theta stimulation polymerizes actin in dendritic spines of hippocampus. J Neurosci (2005) 1.85
Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory. Neuropsychopharmacology (2011) 1.74
Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors. J Neurosci (2010) 1.62
AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke. J Neurosci (2011) 1.58
LTP consolidation: substrates, explanatory power, and functional significance. Neuropharmacology (2006) 1.52
Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. J Neurosci (2009) 1.52
Evidence that long-term potentiation occurs within individual hippocampal synapses during learning. J Neurosci (2007) 1.50
Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation. Neuron (2010) 1.49
Formation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures. Neurobiol Dis (2005) 1.49
Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease. J Neurosci (2007) 1.45
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proc Natl Acad Sci U S A (2009) 1.44
Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling. Proc Natl Acad Sci U S A (2010) 1.43
A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor. J Neurosci (2004) 1.42
Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease. Glia (2007) 1.40
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nat Neurosci (2013) 1.36
Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor. J Neurophysiol (2006) 1.29
The substrates of memory: defects, treatments, and enhancement. Eur J Pharmacol (2008) 1.28
Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome. J Neurosci (2010) 1.22
Ampakines and the threefold path to cognitive enhancement. Trends Neurosci (2006) 1.17
Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology. J Neurochem (2005) 1.17
Benzamide-type AMPA receptor modulators form two subfamilies with distinct modes of action. J Pharmacol Exp Ther (2002) 1.14
Endogenous waves in hippocampal slices. J Neurophysiol (2003) 1.14
Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists. J Neurosci (2005) 1.14
Chronic elevation of brain-derived neurotrophic factor by ampakines. J Pharmacol Exp Ther (2003) 1.12
Synaptic evidence for the efficacy of spaced learning. Proc Natl Acad Sci U S A (2012) 1.11
Integrins modulate fast excitatory transmission at hippocampal synapses. J Biol Chem (2003) 1.09
Integrins regulate NMDA receptor-mediated synaptic currents. J Neurophysiol (2003) 1.09
Ampakines promote spine actin polymerization, long-term potentiation, and learning in a mouse model of Angelman syndrome. Neurobiol Dis (2012) 1.08
Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum. J Neurosci (2010) 1.08
Learning induces neurotrophin signaling at hippocampal synapses. Proc Natl Acad Sci U S A (2010) 1.07
Synaptic plasticity in early aging. Ageing Res Rev (2006) 1.04
Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves. J Physiol (2004) 1.03
Integrin dynamics produce a delayed stage of long-term potentiation and memory consolidation. J Neurosci (2012) 1.02
Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase. J Neurosci (2012) 1.01
The likelihood of cognitive enhancement. Pharmacol Biochem Behav (2011) 1.00
Differences between synaptic plasticity thresholds result in new timing rules for maximizing long-term potentiation. Neuropharmacology (2012) 1.00
Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice. Neurobiol Dis (2010) 0.98
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling. J Neurochem (2005) 0.97
NMDA receptor activation and calpain contribute to disruption of dendritic spines by the stress neuropeptide CRH. J Neurosci (2013) 0.97
LTP induction translocates cortactin at distant synapses in wild-type but not Fmr1 knock-out mice. J Neurosci (2012) 0.96
BDNF signaling during learning is regionally differentiated within hippocampus. J Neurosci (2010) 0.95
BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats. Neurobiol Aging (2010) 0.95
Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain. Am J Pathol (2005) 0.94
Long-term recording of LTP in cultured hippocampal slices. Neural Plast (2002) 0.93
Glucocorticoid receptors are localized to dendritic spines and influence local actin signaling. Mol Neurobiol (2012) 0.91
Blockade of NMDA receptors enhances spontaneous sharp waves in rat hippocampal slices. Neurosci Lett (2005) 0.90
Cholinergic plasticity in the hippocampus. Proc Natl Acad Sci U S A (2003) 0.90
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Chemically induced specification of retinal ganglion cells from human embryonic and induced pluripotent stem cells. Stem Cells Transl Med (2014) 0.90