Published in Antioxid Redox Signal on July 01, 2007
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal (2010) 2.11
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension (2009) 1.61
Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells. Am J Pathol (2008) 1.25
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension (2012) 1.14
Heme oxygenase-1: its therapeutic roles in inflammatory diseases. Immune Netw (2009) 0.97
Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology (2014) 0.94
Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxid Med Cell Longev (2013) 0.89
Induction of protective genes leads to islet survival and function. J Transplant (2011) 0.85
High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis. Diabetol Metab Syndr (2011) 0.85
Biliverdin reductase isozymes in metabolism. Trends Endocrinol Metab (2015) 0.84
Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications. Prostaglandins Other Lipid Mediat (2011) 0.83
Bilirubin Increases Insulin Sensitivity by Regulating Cholesterol Metabolism, Adipokines and PPARγ Levels. Sci Rep (2015) 0.83
Targeting mitochondria as therapeutic strategy for metabolic disorders. ScientificWorldJournal (2014) 0.83
Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cells. Blood (2009) 0.79
Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity. Stem Cells Int (2015) 0.77
Serum bilirubin levels and risk of type 2 diabetes: results from two independent cohorts in middle-aged and elderly Chinese. Sci Rep (2017) 0.75
Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev (2008) 5.34
Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev (2003) 2.52
Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus. Circ Res (2006) 2.26
Bacterial CpG induces hyper-IgM production in CD27(+) memory B cells in primary biliary cirrhosis. Gastroenterology (2005) 2.17
Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med (2005) 2.08
Heme oxygenase-1 gene expression modulates angiotensin II-induced increase in blood pressure. Hypertension (2004) 1.87
L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice. J Lipid Res (2008) 1.80
Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury. Kidney Int (2004) 1.78
D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetes. Circulation (2005) 1.78
Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network. J Clin Microbiol (2009) 1.67
Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J Biol Chem (2003) 1.65
Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation. Am J Physiol Lung Cell Mol Physiol (2006) 1.63
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension (2009) 1.61
Subcutaneous adipose tissue-derived stem cells facilitate colonic mucosal recovery from 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Inflamm Bowel Dis (2008) 1.60
SCID-repopulating cell activity of human cord blood-derived CD34- cells assured by intra-bone marrow injection. Blood (2002) 1.59
Identification of long-term repopulating potential of human cord blood-derived CD34-flt3- severe combined immunodeficiency-repopulating cells by intra-bone marrow injection. Stem Cells (2007) 1.57
Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations. J Immunol (2003) 1.53
Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice. J Pharmacol Exp Ther (2009) 1.51
Plasmacytoid dendritic cells regulate Th cell responses through OX40 ligand and type I IFNs. J Immunol (2004) 1.48
The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. J Lipid Res (2009) 1.48
Increase in heme oxygenase-1 levels ameliorates renovascular hypertension. Kidney Int (2005) 1.48
Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes. Am J Physiol Heart Circ Physiol (2005) 1.47
Endothelial progenitor cell function inversely correlates with long-term glucose control in diabetic patients: association with the attenuation of the heme oxygenase-adiponectin axis. Can J Cardiol (2012) 1.46
Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther (2008) 1.42
Sleep disorders and their association with laboratory pain sensitivity in temporomandibular joint disorder. Sleep (2009) 1.38
Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders. Mol Neurobiol (2011) 1.37
Multilocus sequence identification of Penicillium species in cork bark during plank preparation for the manufacture of stoppers. Res Microbiol (2008) 1.36
Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats. Am J Physiol Heart Circ Physiol (2007) 1.36
Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. J Biol Chem (2006) 1.33
Long-term treatment with the apolipoprotein A1 mimetic peptide increases antioxidants and vascular repair in type I diabetic rats. J Pharmacol Exp Ther (2007) 1.32
Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer. Angiogenesis (2003) 1.30
Maternal microchimerism in underlying pathogenesis of biliary atresia: quantification and phenotypes of maternal cells in the liver. Pediatrics (2008) 1.27
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects. J Pharmacol Exp Ther (2006) 1.22
Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice. Hypertension (2010) 1.18
Nerve growth factor protects against 6-hydroxydopamine-induced oxidative stress by increasing expression of heme oxygenase-1 in a phosphatidylinositol 3-kinase-dependent manner. J Biol Chem (2003) 1.17
Carbon monoxide signaling in promoting angiogenesis in human microvessel endothelial cells. Antioxid Redox Signal (2005) 1.17
Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina. Stem Cells (2002) 1.17
Heme oxygenase-2 is a critical determinant for execution of an acute inflammatory and reparative response. Am J Pathol (2006) 1.17
Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage, reversed by increases in pAMPK, heme oxygenase-1, and adiponectin. Stem Cells (2009) 1.14
Heme oxygenase -1 gene therapy: recent advances and therapeutic applications. Curr Gene Ther (2007) 1.14
Bone-marrow-derived mesenchymal stem cells for organ repair. Stem Cells Int (2013) 1.14
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension (2012) 1.14
Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction. J Am Soc Nephrol (2006) 1.13
HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage. Bone (2009) 1.13
Streamlining HIV testing in the emergency department-leveraging kiosks to provide true universal screening: a usability study. Telemed J E Health (2013) 1.13
CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function. Circ Res (2006) 1.12
Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus. Nat Commun (2012) 1.11
Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. Am J Physiol Renal Physiol (2009) 1.09
Characterization of mesenchymal stem cells isolated from mouse fetal bone marrow. Stem Cells (2005) 1.09
Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes. Am J Physiol Heart Circ Physiol (2004) 1.09
Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes. Free Radic Biol Med (2006) 1.08
Gene targeting and heme oxygenase-1 expression in prevention of hypertension induced by angiotensin II. Hypertension (2008) 1.07
Selective culture of mesodermal progenitor cells. Stem Cells Dev (2009) 1.06
Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD. Am J Physiol Heart Circ Physiol (2009) 1.05
CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. Hypertension (2010) 1.05
Canine bone marrow-derived mesenchymal stromal cells suppress alloreactive lymphocyte proliferation in vitro but fail to enhance engraftment in canine bone marrow transplantation. Biol Blood Marrow Transplant (2010) 1.04
Treatment of streptozotocin-induced diabetes mellitus by transplantation of islet cells plus bone marrow cells via portal vein in rats. Transplantation (2002) 1.04
Targeting heme oxygenase: therapeutic implications for diseases of the cardiovascular system. Cardiol Rev (2009) 1.04
Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes. Prostaglandins Other Lipid Mediat (2011) 1.04
Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow. J Immunol (2004) 1.04
Physiological significance of heme oxygenase in hypertension. Int J Biochem Cell Biol (2008) 1.04
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells. Prostaglandins Other Lipid Mediat (2006) 1.03
Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation. J Bone Miner Metab (2009) 1.02
Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats. Biochem Biophys Res Commun (2004) 1.02
Neuroprotective effect of bone marrow-derived mononuclear cells promoting functional recovery from spinal cord injury. J Neurotrauma (2007) 1.01
Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels. Circ Res (2003) 1.01
Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase. Am J Physiol Heart Circ Physiol (2006) 1.01
Treatment and transfer of emphysema by a new bone marrow transplantation method from normal mice to Tsk mice and vice versa. Stem Cells (2006) 1.01
Comparative analysis of two broad-range PCR assays for pathogen detection in positive-blood-culture bottles: PCR-high-resolution melting analysis versus PCR-mass spectrometry. J Clin Microbiol (2012) 1.01
Mobilization of bone marrow cells by G-CSF rescues mice from cisplatin-induced renal failure, and M-CSF enhances the effects of G-CSF. J Am Soc Nephrol (2005) 1.01
Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ. Stem Cells Dev (2010) 1.01
Risks of immune system treatments. Science (2010) 1.00
Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression. Biochem Biophys Res Commun (2002) 1.00
Serum interleukin 6 before and after therapy with tocilizumab is a principal biomarker in patients with rheumatoid arthritis. J Rheumatol (2013) 1.00
Appendix is a priming site in the development of ulcerative colitis. World J Gastroenterol (2005) 0.99
Plasmacytoid dendritic cells of different origins have distinct characteristics and function: studies of lymphoid progenitors versus myeloid progenitors. J Immunol (2005) 0.99
EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels. Prostaglandins Other Lipid Mediat (2011) 0.99
A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis. J Biol Chem (2002) 0.98
Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis. J Pharmacol Exp Ther (2009) 0.98