1
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Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes.
|
Diabetes
|
2007
|
1.82
|
2
|
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.
|
Nat Med
|
2010
|
1.62
|
3
|
A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease.
|
Mol Genet Metab
|
2007
|
1.61
|
4
|
SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids.
|
PLoS One
|
2012
|
1.29
|