Published in CMAJ on November 01, 1991
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Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med (1985) 2.99
Aspirin use and chronic diseases: a cohort study of the elderly. BMJ (1989) 2.89
Reliability of recall of drug usage and other health-related information. Am J Epidemiol (1982) 2.81
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An overview of the British and American aspirin studies. N Engl J Med (1988) 1.66
Physician variation in anticoagulating patients with atrial fibrillation. Dartmouth Primary Care COOP Project. Arch Intern Med (1990) 1.22
Reactions to acetylsalicylic acid. Can Med Assoc J (1982) 1.02
Trends in self-prescribing and attitudes to self-medication. Practitioner (1983) 0.97
Self-medication in urban and rural Zimbabwean communities. Br J Clin Pharmacol (1989) 0.95
Aspirin and other platelet active drugs. Relationship among dose, effectiveness, and side effects. Chest (1989) 0.81
Use of aspirin for prevention of cardiovascular disease--1981-82 to 1985-86: the Minnesota Heart Survey. Am Heart J (1988) 0.81
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Public awareness of aspirin and sources of aspirin information in a rural Iowa community. J Community Health (1983) 0.79
Therapeutic interventions in acute myocardial infarction. Survey of the ACCP Section on Clinical Cardiology. Chest (1984) 0.78
A population survey on legislative measures to restrict smoking in Ontario: 1. Design, methodology, and sample representativeness. Am J Prev Med (1988) 0.78
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet (2013) 8.16
The Canadian CT Head Rule for patients with minor head injury. Lancet (2001) 7.91
Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications. Arch Intern Med (1995) 7.83
The Canadian C-spine rule for radiography in alert and stable trauma patients. JAMA (2001) 7.48
Management of pain in elderly patients with cancer. SAGE Study Group. Systematic Assessment of Geriatric Drug Use via Epidemiology. JAMA (1998) 6.88
Canadian Atrial Fibrillation Anticoagulation (CAFA) Study. J Am Coll Cardiol (1991) 6.55
The practice guidelines development cycle: a conceptual tool for practice guidelines development and implementation. J Clin Oncol (1995) 6.08
Psychosocial factors related to adolescent smoking: a critical review of the literature. Tob Control (1998) 5.57
Iatrogenic illness on a general medical service at a university hospital. N Engl J Med (1981) 4.82
Comprehensive clinical assessment in community setting: applicability of the MDS-HC. J Am Geriatr Soc (1997) 4.32
A patient decision aid regarding antithrombotic therapy for stroke prevention in atrial fibrillation: a randomized controlled trial. JAMA (1999) 4.31
A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med (1993) 3.67
Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset. Science (1984) 3.47
Decision aids for patients considering options affecting cancer outcomes: evidence of efficacy and policy implications. J Natl Cancer Inst Monogr (1999) 3.45
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev (2007) 3.28
The Ottawa patient decision aids. Eff Clin Pract (1999) 3.22
Assessing the quality of randomized trials: reliability of the Jadad scale. Control Clin Trials (1999) 2.99
Evidence-based medicine and the practicing clinician. J Gen Intern Med (1999) 2.99
Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest (1992) 2.81
Variation in emergency department use of cervical spine radiography for alert, stable trauma patients. CMAJ (1997) 2.79
Antithrombotic therapy in atrial fibrillation. Chest (2001) 2.62
Clinical recommendations using levels of evidence for antithrombotic agents. Chest (1995) 2.52
Oral budesonide for active Crohn's disease. Canadian Inflammatory Bowel Disease Study Group. N Engl J Med (1994) 2.52
Multicentre trial to introduce the Ottawa ankle rules for use of radiography in acute ankle injuries. Multicentre Ankle Rule Study Group. BMJ (1995) 2.50
Perioperative allogeneic blood transfusion does not cause adverse sequelae in patients with cancer: a meta-analysis of unconfounded studies. Br J Surg (1998) 2.44
The rational clinical examination. Does this patient have a clinically important carotid bruit? JAMA (1993) 2.38
Dictated versus database-generated discharge summaries: a randomized clinical trial. CMAJ (1999) 2.28
What is the quality of life for survivors of cardiac arrest? A prospective study. Acad Emerg Med (1999) 2.27
Initiating, conducting and maintaining guidelines development programs. CMAJ (1993) 2.24
Antithrombotic therapy in atrial fibrillation. Chest (1992) 2.21
A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med (1999) 2.19
A prospective cohort study to determine the relationship between serum infliximab concentration and efficacy in patients with luminal Crohn's disease. Aliment Pharmacol Ther (2014) 2.18
Warfarin for atrial fibrillation. The patient's perspective. Arch Intern Med (1996) 2.18
Antithrombotic therapy in atrial fibrillation. Chest (1995) 2.08
Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls. Arch Intern Med (1999) 2.07
Development of the Woman Abuse Screening Tool for use in family practice. Fam Med (1996) 2.03
Compliance with physician advice to quit smoking: a review of the literature. Prev Med (1982) 1.95
The use of differential display-PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages. Mol Microbiol (1996) 1.94
Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease. North American Azathioprine Study Group. Gastroenterology (1999) 1.84
Use of statins and the subsequent development of deep vein thrombosis. Arch Intern Med (2001) 1.82
Preoperative autologous donation decreases allogeneic transfusion but increases exposure to all red blood cell transfusion: results of a meta-analysis. International Study of Perioperative Transfusion (ISPOT) Investigators. Arch Intern Med (1998) 1.68
Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites. Br J Clin Pharmacol (1984) 1.66
Nursing homes in 10 nations: a comparison between countries and settings. Age Ageing (1997) 1.65
The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med (2001) 1.65
Comparison of teleconsultations and face-to-face consultations: preliminary results of a United Kingdom multicentre teledermatology study. Br J Dermatol (1998) 1.63
Integrated health information systems based on the RAI/MDS series of instruments. Healthc Manage Forum (1999) 1.63
Clinical course and costs of care for Crohn's disease: Markov model analysis of a population-based cohort. Gastroenterology (1999) 1.61
An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial. Gastroenterology (2001) 1.57
Evaluation of a decision aid for patients considering autologous blood donation before open-heart surgery. CMAJ (2001) 1.54
Care of the elderly in the emergency department. Ann Emerg Med (1986) 1.53
When should hypertension be treated? The different perspectives of Canadian family physicians and patients. CMAJ (2000) 1.51
Cyclosporin prevents diabetes in BB Wistar rats. Lancet (1983) 1.50
Asymptomatic Wolff-Parkinson-White. Should we intervene? Circulation (1989) 1.47
Autologous versus allogeneic transfusion: patients' perceptions and experiences. CMAJ (1999) 1.45
An economic analysis of the Ottawa knee rule. Ann Emerg Med (1999) 1.43
Low-dose cyclosporine for the treatment of Crohn's disease. The Canadian Crohn's Relapse Prevention Trial Investigators. N Engl J Med (1994) 1.43
Randomised study of n of 1 trials versus standard practice. BMJ (1996) 1.41
A meta-analysis of the effectiveness of cell salvage to minimize perioperative allogeneic blood transfusion in cardiac and orthopedic surgery. International Study of Perioperative Transfusion (ISPOT) Investigators. Anesth Analg (1999) 1.40
Health behaviours and socio-economic status in Ontario, Canada. Eur J Epidemiol (1997) 1.40
Heterogeneity among smokers and non-smokers in attitudes and behaviour regarding smoking and smoking restrictions. Tob Control (2000) 1.39
Simplified liquid-chromotographic analysis for cyclosporin A, and comparison with radioimmunoassay. Clin Chem (1983) 1.38
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev (2001) 1.37
The relationship of cigarette prices and no-smoking bylaws to the prevalence of smoking in Canada. Am J Public Health (1997) 1.32
Review article: a clinician's guide for therapeutic drug monitoring of infliximab in inflammatory bowel disease. Aliment Pharmacol Ther (2013) 1.32
How well is the clinical importance of study results reported? An assessment of randomized controlled trials. CMAJ (2001) 1.31
Oral budesonide as maintenance treatment for Crohn's disease: a placebo-controlled, dose-ranging study. Canadian Inflammatory Bowel Disease Study Group. Gastroenterology (1996) 1.31
Does self-administration of a quality of life index for inflammatory bowel disease change the results? J Clin Epidemiol (1996) 1.30
Variation in ED use of computed tomography for patients with minor head injury. Ann Emerg Med (1997) 1.29
Implementing advance directives in the primary care setting. Arch Intern Med (1994) 1.28
A randomized study comparing a patient-directed hypertension management strategy with usual office-based care. Am J Hypertens (1997) 1.27
Pain management in frail, community-living elderly patients. Arch Intern Med (2001) 1.26
Development of a decision aid for atrial fibrillation who are considering antithrombotic therapy. J Gen Intern Med (2000) 1.23
Passive smoking and low birthweight. Lancet (1989) 1.21
New tobacco products: do smokers like them? Tob Control (2006) 1.21
Cost-effectiveness analysis of potential improvements to emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med (1996) 1.21
Awareness and use of the Ottawa ankle and knee rules in 5 countries: can publication alone be enough to change practice? Ann Emerg Med (2001) 1.19
Does acute normovolemic hemodilution reduce perioperative allogeneic transfusion? A meta-analysis. The International Study of Perioperative Transfusion. Anesth Analg (1998) 1.17
Comprehensive tobacco control policies and the smoking behaviour of Canadian adults. Tob Control (2001) 1.16
Effectiveness of emergency medical services for victims of out-of-hospital cardiac arrest: a metaanalysis. Ann Emerg Med (1996) 1.15
Cost-effectiveness analysis of the Ottawa Ankle Rules. Ann Emerg Med (1995) 1.13
The medical chief residency and its relation to academic sections of general medicine. Am J Med (1983) 1.11
Cyclosporine for treatment of early type I diabetes: preliminary results. N Engl J Med (1983) 1.10
A double-blind study of 250 cases comparing cemented with cementless total hip arthroplasty. Cost-effectiveness and its impact on health-related quality of life. Clin Orthop Relat Res (1994) 1.10
A policy analysis of major decisions relating to Creutzfeldt-Jakob disease and the blood supply. CMAJ (2001) 1.10
Patient preference-based treatment thresholds and recommendations: a comparison of decision-analytic modeling with the probability-tradeoff technique. Med Decis Making (2001) 1.10
Cyclosporin A: a powerful immunosuppressant. Can Med Assoc J (1982) 1.09
Support among smokers and nonsmokers for restrictions on smoking. Am J Prev Med (1996) 1.09
Models of the relationship of stress, depression, and other psychosocial factors to smoking behavior: a comparison of a cohort of students in grades 6 and 8. Prev Med (2000) 1.07
Surveying physicians to determine the minimal important difference: implications for sample-size calculation. J Clin Epidemiol (1999) 1.06
Cushing's syndrome in association with a carcinoid tumor of the lung. J Clin Endocrinol Metab (1967) 1.05
Long-term pulmonary function abnormalities and survival after allogeneic marrow transplantation. Bone Marrow Transplant (2004) 1.05
Emergency physicians' attitudes toward and use of clinical decision rules for radiography. Acad Emerg Med (1998) 1.05
Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice. Chest (1999) 1.04
A survey of clinician attitudes and management practices in hypertension. J Hum Hypertens (1997) 1.04
Multivariate statistical models for predicting change in smoking behavior following physician advice to quit smoking. Prev Med (1982) 1.02
An evaluation of utility measurement in Crohn's disease. Inflamm Bowel Dis (1997) 1.01