Published in Brain on May 23, 2007
Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants. Neuroimage (2009) 3.74
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A (2010) 2.85
Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimers Res Ther (2011) 2.51
Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging (2009) 2.14
White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI. Brain (2009) 2.08
Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease. Brain (2013) 2.05
Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neuroimage (2009) 1.92
Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults. J Neurosci (2011) 1.74
Current and future uses of neuroimaging for cognitively impaired patients. Lancet Neurol (2008) 1.49
Dementia with Lewy bodies and Alzheimer disease: neurodegenerative patterns characterized by DTI. Neurology (2010) 1.45
Distinct cerebral perfusion patterns in FTLD and AD. Neurology (2010) 1.38
Neuroimaging and other biomarkers for Alzheimer's disease: the changing landscape of early detection. Annu Rev Clin Psychol (2013) 1.28
White matter diffusion alterations in normal women at risk of Alzheimer's disease. Neurobiol Aging (2008) 1.22
White matter integrity, creativity, and psychopathology: disentangling constructs with diffusion tensor imaging. PLoS One (2010) 1.18
Direct visualization of the perforant pathway in the human brain with ex vivo diffusion tensor imaging. Front Hum Neurosci (2010) 1.13
Principal component analysis of FDG PET in amnestic MCI. Eur J Nucl Med Mol Imaging (2008) 1.13
Microstructural white matter changes, not hippocampal atrophy, detect early amnestic mild cognitive impairment. PLoS One (2013) 1.12
Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease. Alzheimers Dement (2012) 1.11
The fornix sign: a potential sign for Alzheimer's disease based on diffusion tensor imaging. J Neuroimaging (2011) 1.10
Inflammatory process in Alzheimer's Disease. Front Integr Neurosci (2013) 1.10
Novel MRI techniques in the assessment of dementia. Eur J Nucl Med Mol Imaging (2008) 1.07
White matter integrity and vulnerability to Alzheimer's disease: preliminary findings and future directions. Biochim Biophys Acta (2011) 1.07
Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals. JAMA Neurol (2013) 1.06
Multi-modal MRI analysis with disease-specific spatial filtering: initial testing to predict mild cognitive impairment patients who convert to Alzheimer's disease. Front Neurol (2011) 1.06
Commentary on "a roadmap for the prevention of dementia II: Leon Thal Symposium 2008." Prevention trials in persons at risk for dominantly inherited Alzheimer's disease: opportunities and challenges. Alzheimers Dement (2009) 1.02
DTI analyses and clinical applications in Alzheimer's disease. J Alzheimers Dis (2011) 1.02
Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation. Neuroimage Clin (2014) 1.02
Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer's Disease. Front Aging Neurosci (2012) 1.00
Neurosteroids as regenerative agents in the brain: therapeutic implications. Nat Rev Endocrinol (2013) 0.99
Cigarette smoking and white matter microstructure. Psychopharmacology (Berl) (2012) 0.99
White matter predictors of cognitive functioning in older adults. J Int Neuropsychol Soc (2012) 0.98
White-matter abnormalities in brain during early abstinence from methamphetamine abuse. Psychopharmacology (Berl) (2010) 0.98
Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations. J Neurol Neurosurg Psychiatry (2012) 0.97
White matter tract signatures of the progressive aphasias. Neurobiol Aging (2013) 0.95
MRI markers for mild cognitive impairment: comparisons between white matter integrity and gray matter volume measurements. PLoS One (2013) 0.94
The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology (2013) 0.92
Early structural changes in individuals at risk of familial Alzheimer's disease: a volumetry and magnetization transfer MR imaging study. J Neurol (2009) 0.92
Neuroimaging biomarkers of neurodegenerative diseases and dementia. Semin Neurol (2013) 0.92
Posterior cingulum white matter disruption and its associations with verbal memory and stroke risk in mild cognitive impairment. J Alzheimers Dis (2012) 0.92
Event-related potential markers of brain changes in preclinical familial Alzheimer disease. Neurology (2011) 0.91
Current concepts of mild cognitive impairment and their applicability to persons at-risk for familial Alzheimer's disease. Curr Alzheimer Res (2009) 0.91
Cortical event-related potentials in preclinical familial Alzheimer disease. Neurology (2009) 0.91
Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease. Dement Geriatr Cogn Disord (2011) 0.88
White matter changes in patients with amnestic mild cognitive impairment detected by diffusion tensor imaging. PLoS One (2013) 0.88
White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults. Neurobiol Aging (2014) 0.87
Recent advances in imaging Alzheimer's disease. J Alzheimers Dis (2013) 0.85
Cognitive reserve, cortical plasticity and resistance to Alzheimer's disease. Alzheimers Res Ther (2012) 0.85
The fornix in mild cognitive impairment and Alzheimer's disease. Front Aging Neurosci (2015) 0.83
Longitudinal study of carbon monoxide intoxication by diffusion tensor imaging with neuropsychiatric correlation. J Psychiatry Neurosci (2010) 0.83
Imaging genetics of structural brain connectivity and neural integrity markers. Neuroimage (2009) 0.83
Fractional anisotropy of the fornix and hippocampal atrophy in Alzheimer's disease. Front Aging Neurosci (2014) 0.82
Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy. PLoS One (2014) 0.81
Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations. Am J Neurodegener Dis (2013) 0.81
The contributions of MRI-based measures of gray matter, white matter hyperintensity, and white matter integrity to late-life cognition. AJNR Am J Neuroradiol (2012) 0.81
Imaging endpoints for clinical trials in Alzheimer's disease. Alzheimers Res Ther (2014) 0.80
Diffusion imaging changes in grey matter in Alzheimer's disease: a potential marker of early neurodegeneration. Alzheimers Res Ther (2015) 0.80
Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment. Pharmacogenet Genomics (2009) 0.80
White matter integrity determined with diffusion tensor imaging in older adults without dementia: influence of amyloid load and neurodegeneration. JAMA Neurol (2014) 0.80
Fornix as an imaging marker for episodic memory deficits in healthy aging and in various neurological disorders. Front Aging Neurosci (2015) 0.80
Associations between white matter microstructure and cognitive performance in old and very old age. PLoS One (2013) 0.79
Can complex visual discrimination deficits in amnesia be attributed to the medial temporal lobe? An investigation into the effects of medial temporal lobe damage on brain connectivity. Hippocampus (2012) 0.79
The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease. Acta Neuropathol Commun (2013) 0.79
Therapeutics for cognitive aging. Ann N Y Acad Sci (2010) 0.79
High-throughput neuro-imaging informatics. Front Neuroinform (2013) 0.79
Brain imaging of neurovascular dysfunction in Alzheimer's disease. Acta Neuropathol (2016) 0.79
An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction. Glia (2011) 0.79
Effect of Simulated Microgravity on Human Brain Gray Matter and White Matter--Evidence from MRI. PLoS One (2015) 0.79
Alzheimer's disease and the fornix. Front Aging Neurosci (2014) 0.78
Clinical, biological, and imaging features of monogenic Alzheimer's Disease. Biomed Res Int (2013) 0.77
Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease. Hum Brain Mapp (2012) 0.77
Increased fMRI signal with age in familial Alzheimer's disease mutation carriers. Neurobiol Aging (2010) 0.77
Full diffusion characterization implicates regionally disparate neuropathology in mild cognitive impairment. Brain Struct Funct (2013) 0.76
Microstructural White Matter Properties Mediate the Association between APOE and Perceptual Speed in Very Old Persons without Dementia. PLoS One (2015) 0.76
Connectome imaging for mapping human brain pathways. Mol Psychiatry (2017) 0.76
Insight from uncertainty: bootstrap-derived diffusion metrics differentially predict memory function among older adults. Brain Struct Funct (2014) 0.75
Mary S. Easton Center of Alzheimer's Disease Research at UCLA: advancing the therapeutic imperative. J Alzheimers Dis (2010) 0.75
Recent Developments in Diffusion Tensor Imaging of Brain. Radiol Open J (2015) 0.75
Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging. PLoS One (2017) 0.75
No Evidence That Short-Term Cognitive or Physical Training Programs or Lifestyles Are Related to Changes in White Matter Integrity in Older Adults at Risk of Dementia. Front Hum Neurosci (2017) 0.75
Morphological and Microstructural Changes of the Hippocampus in Early MCI: A Study Utilizing the Alzheimer's Disease Neuroimaging Initiative Database. J Clin Neurol (2017) 0.75
Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease. Neuroimage Clin (2016) 0.75
Multimodal Brain Imaging Reveals Structural Differences in Alzheimer's Disease Polygenic Risk Carriers: A Study in Healthy Young Adults. Biol Psychiatry (2016) 0.75
The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease. Neuroimage (2016) 0.75
Widespread white matter and conduction defects in PSEN1-related spastic paraparesis. Neurobiol Aging (2016) 0.75
White Matter Integrity Declined Over 6-Months, but Dance Intervention Improved Integrity of the Fornix of Older Adults. Front Aging Neurosci (2017) 0.75
White-matter integrity on DTI and the pathologic staging of Alzheimer's disease. Neurobiol Aging (2017) 0.75
The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc (2005) 27.90
The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods. J Magn Reson Imaging (2008) 14.68
Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
Mild cognitive impairment. Lancet (2006) 10.21
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol (2010) 8.74
A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimers Dement (2008) 6.39
Frontal-subcortical neuronal circuits and clinical neuropsychiatry: an update. J Psychosom Res (2002) 4.17
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nat Med (2009) 4.11
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association. J Neuropsychiatry Clin Neurosci (2002) 3.26
Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps. Arch Neurol (2006) 3.11
3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease. Brain (2006) 2.73
Common genetic variants, acting additively, are a major source of risk for autism. Mol Autism (2012) 2.67
Complementary roles of cholecystokinin- and parvalbumin-expressing GABAergic neurons in hippocampal network oscillations. J Neurosci (2005) 2.64
Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease mild cognitive impairment, and elderly controls. Neuroimage (2008) 2.30
The reorganization and reactivation of hippocampal maps predict spatial memory performance. Nat Neurosci (2010) 2.29
Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Hum Brain Mapp (2009) 2.28
Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Neuroimage (2008) 2.25
Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging (2004) 2.23
Differences between smokers and nonsmokers in regional gray matter volumes and densities. Biol Psychiatry (2004) 2.20
Frontal-subcortical circuitry and behavior. Dialogues Clin Neurosci (2007) 2.14
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
Executive dysfunction and apathy predict functional impairment in Alzheimer disease. Am J Geriatr Psychiatry (2003) 2.07
Gamma oscillatory firing reveals distinct populations of pyramidal cells in the CA1 region of the hippocampus. J Neurosci (2008) 1.99
White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. Arch Neurol (2003) 1.93
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Management of agitation and aggression associated with Alzheimer disease. Nat Rev Neurol (2009) 1.86
Delusional thoughts and regional frontal/temporal cortex metabolism in Alzheimer's disease. Am J Psychiatry (2003) 1.86
A potential role of the curry spice curcumin in Alzheimer's disease. Curr Alzheimer Res (2005) 1.85
Increased amygdala activation during mania: a functional magnetic resonance imaging study. Am J Psychiatry (2005) 1.84
A collaborative study of the emergence and clinical features of the major depressive syndrome of Alzheimer's disease. Am J Psychiatry (2003) 1.83
Comparison of AdaBoost and support vector machines for detecting Alzheimer's disease through automated hippocampal segmentation. IEEE Trans Med Imaging (2009) 1.80
Effective pharmacologic management of Alzheimer's disease. Am J Med (2007) 1.79
Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry (2002) 1.75
3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging (2010) 1.70
Ambulatory blood pressure and the brain: a 5-year follow-up. Neurology (2005) 1.65
A short cervix in women with preterm labor and intact membranes: a risk factor for microbial invasion of the amniotic cavity. Am J Obstet Gynecol (2005) 1.64
Antibiotic administration to patients with preterm premature rupture of membranes does not eradicate intra-amniotic infection. J Matern Fetal Neonatal Med (2007) 1.62
Neuropsychiatric manifestations in mild cognitive impairment: a systematic review of the literature. Dement Geriatr Cogn Disord (2007) 1.61
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. J Alzheimers Dis (2010) 1.57
Three-dimensional gray matter atrophy mapping in mild cognitive impairment and mild Alzheimer disease. Arch Neurol (2007) 1.55
Abuse of amphetamines and structural abnormalities in the brain. Ann N Y Acad Sci (2008) 1.54
Mild cognitive impairment is associated with characteristic neuropsychiatric symptoms. Alzheimer Dis Assoc Disord (2004) 1.53
Place-selective firing contributes to the reverse-order reactivation of CA1 pyramidal cells during sharp waves in open-field exploration. Eur J Neurosci (2007) 1.49
Identification of patients at risk for early onset and/or severe preeclampsia with the use of uterine artery Doppler velocimetry and placental growth factor. Am J Obstet Gynecol (2007) 1.47
Automated 3D mapping of baseline and 12-month associations between three verbal memory measures and hippocampal atrophy in 490 ADNI subjects. Neuroimage (2010) 1.45
3D comparison of low, intermediate, and advanced hippocampal atrophy in MCI. Hum Brain Mapp (2010) 1.40
Disease-modifying therapies in Alzheimer's disease. Alzheimers Dement (2008) 1.39
Neuropsychiatric symptoms and quality of life in Alzheimer disease. Am J Geriatr Psychiatry (2005) 1.38
Dementia with parkinsonism: what is the diagnosis? Rev Neurol Dis (2004) 1.38
Neuropsychiatric symptoms are associated with progression from mild cognitive impairment to Alzheimer's disease. Dement Geriatr Cogn Disord (2007) 1.35
Serotonin 1A receptors in the living brain of Alzheimer's disease patients. Proc Natl Acad Sci U S A (2006) 1.34
Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology (2007) 1.33
The A431E mutation in PSEN1 causing familial Alzheimer's disease originating in Jalisco State, Mexico: an additional fifteen families. Neurogenetics (2006) 1.31
Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia. Mov Disord (2010) 1.31
Reduced white matter integrity in attention-deficit hyperactivity disorder. Neuroreport (2008) 1.31
Prevalence and impact of medical comorbidity in Alzheimer's disease. J Gerontol A Biol Sci Med Sci (2002) 1.30
Positron emission tomography metabolic correlates of apathy in Alzheimer disease. Arch Neurol (2007) 1.27
Frequency and characteristics of anxiety among patients with Alzheimer's disease and related dementias. J Neuropsychiatry Clin Neurosci (2003) 1.27
Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging. Magn Reson Imaging (2006) 1.26
Structural correlates of apathy in Alzheimer's disease. Dement Geriatr Cogn Disord (2007) 1.25
Automatic subcortical segmentation using a contextual model. Med Image Comput Comput Assist Interv (2008) 1.25
Epidemiology and genetics of frontotemporal dementia/Pick's disease. Ann Neurol (2003) 1.24
Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases. Ann N Y Acad Sci (2004) 1.23
Apolipoprotein E genotype and age-related myelin breakdown in healthy individuals: implications for cognitive decline and dementia. Arch Gen Psychiatry (2006) 1.22
Effects of ApoE4 and maternal history of dementia on hippocampal atrophy. Neurobiol Aging (2010) 1.22
Idiopathic vaginal bleeding during pregnancy as the only clinical manifestation of intrauterine infection. J Matern Fetal Neonatal Med (2005) 1.20
Gray-matter volume in methamphetamine dependence: cigarette smoking and changes with abstinence from methamphetamine. Drug Alcohol Depend (2012) 1.20
Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb Cortex (2008) 1.20
Apathy symptom profile and behavioral associations in frontotemporal dementia vs dementia of Alzheimer type. Arch Neurol (2009) 1.17
Independent contributions of neural and "higher-order" deficits to symptoms in Alzheimer's disease: a latent variable modeling approach. Alzheimers Dement (2006) 1.16
The Sleep Disorders Inventory: an instrument for studies of sleep disturbance in persons with Alzheimer's disease. J Sleep Res (2003) 1.15
Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke. J Neurosci (2011) 1.14
Frontal-subcortical dementias. Neurologist (2008) 1.14
The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimers Dement (2012) 1.14
Proton magnetic resonance spectroscopic imaging of the brain in childhood autism. Biol Psychiatry (2003) 1.13
Depressive symptoms in mild cognitive impairment predict greater atrophy in Alzheimer's disease-related regions. Biol Psychiatry (2012) 1.13
Neuropsychiatric symptoms in the dementias. Curr Opin Neurol (2002) 1.13
Comorbidity in dementia: an autopsy study. Arch Pathol Lab Med (2004) 1.12
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood. J Alzheimers Dis (2012) 1.11
Adjusting head circumference for covariates in autism: clinical correlates of a highly heritable continuous trait. Biol Psychiatry (2013) 1.11
The Spanish translation and adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease Centers. Alzheimer Dis Assoc Disord (2009) 1.09
Apolipoprotein E genotype is associated with temporal and hippocampal atrophy rates in healthy elderly adults: a tensor-based morphometry study. J Alzheimers Dis (2011) 1.09
Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol. J Alzheimers Dis (2011) 1.08
Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb. J Neurosci (2009) 1.06
3D mapping of mini-mental state examination performance in clinical and preclinical Alzheimer disease. Alzheimer Dis Assoc Disord (2006) 1.06
Brain imaging in pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry (2008) 1.06
Early-onset Alzheimer's disease is associated with greater pathologic burden. J Geriatr Psychiatry Neurol (2007) 1.05
A blood gene expression marker of early Alzheimer's disease. J Alzheimers Dis (2013) 1.05
Functional characterization of the three genes encoding 1-deoxy-D-xylulose 5-phosphate synthase in maize. J Exp Bot (2011) 1.05
Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting. J Neurosci (2010) 1.05