Published in Circulation on May 28, 2007
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ (2012) 3.05
Increased perioperative mortality following aprotinin withdrawal: a real-world analysis of blood management strategies in adult cardiac surgery. Intensive Care Med (2013) 1.37
Early postoperative outcomes and blood product utilization in adult cardiac surgery: the post-aprotinin era. Circulation (2011) 1.24
The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis. CMAJ (2008) 1.12
Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies. BMJ (2012) 1.07
Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis. Crit Care (2010) 0.96
Recommendations for the transfusion management of patients in the peri-operative period. I. The pre-operative period. Blood Transfus (2011) 0.95
Systematic review and meta-analysis of perioperative intravenous tranexamic acid use in spinal surgery. PLoS One (2013) 0.93
Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. Eur Spine J (2012) 0.85
Effectiveness of tranexamic acid in reducing blood loss in spinal surgery: a meta-analysis. BMC Musculoskelet Disord (2014) 0.84
Differential effects of epsilon-aminocaproic acid and aprotinin on matrix metalloproteinase release in patients following cardiopulmonary bypass. J Cardiovasc Pharmacol (2008) 0.83
Brain protection in cardiac surgery. Anesthesiol Clin (2008) 0.82
Topical versus intravenous tranexamic acid as a blood conservation intervention for reduction of post-operative bleeding in hemiarthroplasty. Anesth Essays Res (2015) 0.82
Pharmacologic strategies for combating the inflammatory response. J Extra Corpor Technol (2007) 0.82
Is aprotinin safe to use in a cohort at increased risk for thrombotic events: results from a randomized, prospective trial in off-pump coronary artery bypass. Ann Thorac Surg (2008) 0.82
Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis. PLoS One (2015) 0.81
Antiplatelet drugs: mechanisms and risks of bleeding following cardiac operations. Int J Angiol (2011) 0.80
Cardiac-surgery associated acute kidney injury requiring renal replacement therapy. A Spanish retrospective case-cohort study. BMC Nephrol (2009) 0.79
Antifibrinolytic therapy: evidence, bias, confounding (and politics!). J Extra Corpor Technol (2007) 0.78
Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial. Clin Pharmacol Ther (2012) 0.77
Valid comparisons of antifibrinolytic agents used in cardiac surgery. Circulation (2007) 0.77
Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials. Int J Clin Exp Pathol (2015) 0.76
Safety and efficacy of caproamin fides and tranexamic Acid versus placebo in patients undergoing coronary artery revascularization. J Cardiovasc Thorac Res (2014) 0.75
The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. PLoS One (2015) 0.75
The aprotinin saga and the risks of conducting meta-analyses on small randomised controlled trials - a critique of a Cochrane review. BMC Health Serv Res (2009) 0.75
Efficacy of combined use of intraarticular and intravenous tranexamic acid in total knee arthroplasty. Ann Transl Med (2015) 0.75
Hyperfibrinolysis after parapelvic cyst surgery: A case report. Exp Ther Med (2012) 0.75
Continuous localized monitoring of plasmin activity identifies differential and regional effects of the serine protease inhibitor aprotinin: relevance to antifibrinolytic therapy. J Cardiovasc Pharmacol (2011) 0.75
Seizures Following Cardiopulmonary Bypass. J Extra Corpor Technol (2016) 0.75
The prognostic value of using the duration of acute kidney injury in cardiac surgery: an example using two antifibrinolytics. J Extra Corpor Technol (2011) 0.75
Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion. Interact Cardiovasc Thorac Surg (2012) 0.75
Commentary: Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery. Front Cardiovasc Med (2017) 0.75
Efficacy of antifibrinolytic agents on surgical bleeding and transfusion requirements in spine surgery: a meta-analysis. Eur Spine J (2016) 0.75
Surgical skill and complication rates after bariatric surgery. N Engl J Med (2013) 9.39
Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med (2007) 6.72
An evidence-based review of the practice of cardiopulmonary bypass in adults: a focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response. J Thorac Cardiovasc Surg (2006) 3.09
Hospital quality and the cost of inpatient surgery in the United States. Ann Surg (2012) 3.04
Measuring the quality of surgical care: structure, process, or outcomes? J Am Coll Surg (2004) 2.86
Long-term survival after cardiac surgery is predicted by estimated glomerular filtration rate. Ann Thorac Surg (2008) 2.65
Long-term outcomes of endoscopic vein harvesting after coronary artery bypass grafting. Circulation (2011) 2.44
The association of perioperative red blood cell transfusions and decreased long-term survival after cardiac surgery. Anesth Analg (2009) 2.32
Serious renal dysfunction after percutaneous coronary interventions can be predicted. Am Heart J (2007) 2.30
Descriptive epidemiology and prior healthcare utilization of patients in the Spine Patient Outcomes Research Trial's (SPORT) three observational cohorts: disc herniation, spinal stenosis, and degenerative spondylolisthesis. Spine (Phila Pa 1976) (2006) 2.30
Study designs for PDSA quality improvement research. Qual Manag Health Care (2004) 2.22
Prediction of survival after coronary revascularization: modeling short-term, mid-term, and long-term survival. Ann Thorac Surg (2009) 1.86
Racial disparities in late survival after rectal cancer surgery. J Am Coll Surg (2006) 1.83
The comparative effectiveness of sleeve gastrectomy, gastric bypass, and adjustable gastric banding procedures for the treatment of morbid obesity. Ann Surg (2013) 1.72
The identification and development of Canadian coronary artery bypass graft surgery quality indicators. J Thorac Cardiovasc Surg (2005) 1.68
Predicting vascular complications in percutaneous coronary interventions. Am Heart J (2003) 1.58
Comparing long-term survival of patients with multivessel coronary disease after CABG or PCI: analysis of BARI-like patients in northern New England. Circulation (2005) 1.58
Long-term survival of the very elderly undergoing coronary artery bypass grafting. Ann Thorac Surg (2008) 1.56
Perioperative increases in serum creatinine are predictive of increased 90-day mortality after coronary artery bypass graft surgery. Circulation (2006) 1.53
Volume and process of care in high-risk cancer surgery. Cancer (2006) 1.52
Cardiopulmonary bypass recommendations in adults: the northern New England experience. J Extra Corpor Technol (2008) 1.52
Neurocognitive outcomes of off-pump versus on-pump coronary artery bypass: a prospective randomized controlled trial. Ann Thorac Surg (2007) 1.50
Comparative effectiveness of unfractionated and low-molecular-weight heparin for prevention of venous thromboembolism following bariatric surgery. Arch Surg (2012) 1.48
Data feedback and clinical process improvement in acute myocardial infarction. Am Heart J (2005) 1.47
Intraoperative red blood cell transfusion during coronary artery bypass graft surgery increases the risk of postoperative low-output heart failure. Circulation (2006) 1.44
Determination of etiologic mechanisms of strokes secondary to coronary artery bypass graft surgery. Stroke (2003) 1.43
Multivariable prediction of renal insufficiency developing after cardiac surgery. Circulation (2007) 1.42
Development and validation of a prediction model for strokes after coronary artery bypass grafting. Ann Thorac Surg (2003) 1.39
Racial variation in treatment preferences and willingness to randomize in the Spine Patient Outcomes Research Trial (SPORT). Spine (Phila Pa 1976) (2006) 1.32
Detection and elimination of microemboli related to cardiopulmonary bypass. Circ Cardiovasc Qual Outcomes (2009) 1.28
Do hospitals with low mortality rates in coronary artery bypass also perform well in valve replacement? Ann Thorac Surg (2003) 1.19
Does safe dosing of iodinated contrast prevent contrast-induced acute kidney injury? Circ Cardiovasc Interv (2010) 1.18
Long-term survival of patients with chronic obstructive pulmonary disease undergoing coronary artery bypass surgery. Circulation (2006) 1.17
Coronary heart disease and prevention in the United States. N Engl J Med (2010) 1.16
10-year follow-up of patients with and without mediastinitis. Semin Thorac Cardiovasc Surg (2004) 1.16
Multivariable prediction of in-hospital mortality associated with aortic and mitral valve surgery in Northern New England. Ann Thorac Surg (2004) 1.12
A multicenter comparison of intraaortic balloon pump utilization in isolated coronary artery bypass graft surgery. Ann Thorac Surg (2003) 1.10
Long-term survival of the very elderly undergoing aortic valve surgery. Circulation (2009) 1.09
Association of bacterial infection and red blood cell transfusion after coronary artery bypass surgery. Ann Thorac Surg (2002) 1.08
Long-term survival after surgery versus percutaneous intervention in octogenarians with multivessel coronary disease. Ann Thorac Surg (2007) 1.07
Long-term survival of dialysis patients after coronary bypass grafting. Ann Thorac Surg (2002) 1.03
Outcomes of patients undergoing concomitant aortic and mitral valve surgery in northern new England. Circulation (2009) 1.02
Intra- and postoperative predictors of stroke after coronary artery bypass grafting. Ann Thorac Surg (2003) 0.99
The diabetic disadvantage: historical outcomes measures in diabetic patients undergoing cardiac surgery -- the pre-intravenous insulin era. Semin Thorac Cardiovasc Surg (2006) 0.99
Microemboli from cardiopulmonary bypass are associated with a serum marker of brain injury. J Extra Corpor Technol (2010) 0.98
Perioperative stroke and long-term survival after coronary bypass graft surgery. Ann Thorac Surg (2005) 0.96
The effects of bariatric surgery on asthma severity. Obes Surg (2011) 0.96
Sodium bicarbonate plus N-acetylcysteine prophylaxis: a meta-analysis. JACC Cardiovasc Interv (2009) 0.95
Survival in patients with peripheral vascular disease after percutaneous coronary intervention and coronary artery bypass graft surgery. Ann Thorac Surg (2004) 0.95
Effect of diabetes and associated conditions on long-term survival after coronary artery bypass graft surgery. Circulation (2004) 0.92
How do centres begin the process to prevent contrast-induced acute kidney injury: a report from a new regional collaborative. BMJ Qual Saf (2011) 0.91
Rationalising the treatment of anaemia in cardiac surgery: short and mid-term results from a local quality improvement initiative. Qual Saf Health Care (2010) 0.91
Preoperative white blood cell count and mortality and morbidity after coronary artery bypass grafting. Ann Thorac Surg (2003) 0.90
Aprotinin in cardiac surgery. N Engl J Med (2006) 0.89
Lowest core body temperature and adverse outcomes associated with coronary artery bypass surgery. Perfusion (2003) 0.88
Current issues in quality improvement in cystic fibrosis. Clin Chest Med (2007) 0.87
The preoperative intraaortic balloon pump in coronary bypass surgery: a lack of evidence of effectiveness. Am Heart J (2005) 0.87
The effect of comorbid illness on mortality outcomes in cardiac surgery. Arch Surg (2002) 0.86
Characteristics of hospitals performing bariatric surgery. JAMA (2006) 0.86
Intraoperative and postoperative variables associated with strokes following cardiac surgery. Heart Surg Forum (2004) 0.84
Highest core temperature during cardiopulmonary bypass and rate of mediastinitis. Perfusion (2004) 0.83
The association between heart rate and in-hospital mortality after coronary artery bypass graft surgery. Anesth Analg (2002) 0.83
Comparison of three measurements of cardiac surgery mortality for the Northern New England Cardiovascular Disease Study Group. Ann Thorac Surg (2006) 0.80
Cardiac troponin T levels in on- and off-pump coronary artery bypass surgery. Heart Surg Forum (2007) 0.80
Neurologic injury associated with CABG surgery: outcomes, mechanisms, and opportunities for improvement. Heart Surg Forum (2004) 0.78
A method for identifying mechanisms of neurologic injury from cardiac surgery. Heart Surg Forum (2004) 0.78
Mitral valve repair and replacement in northern New England. Am Heart J (2003) 0.78
Long-term survival and cardiac troponin T elevation in on- and off-pump coronary artery bypass surgery. Heart Surg Forum (2008) 0.77
Does tight glucose control prevent myocardial injury and inflammation? J Extra Corpor Technol (2011) 0.76
Using biomarkers to improve the preoperative prediction of death in coronary artery bypass graft patients. J Extra Corpor Technol (2010) 0.75
Embolic activity subsequent to injection of the internal mammary artery with papaverine hydrochloride. Heart Surg Forum (2005) 0.75
Taking the measure of clinical care. Can J Cardiol (2003) 0.75