Published in J Am Geriatr Soc on June 01, 2007
A standard procedure for creating a frailty index. BMC Geriatr (2008) 4.40
Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J Am Geriatr Soc (2008) 2.94
Prognostic significance of potential frailty criteria. J Am Geriatr Soc (2008) 2.69
Measures of frailty in population-based studies: an overview. BMC Geriatr (2013) 1.69
Development and validation of a multidimensional prognostic index for one-year mortality from comprehensive geriatric assessment in hospitalized older patients. Rejuvenation Res (2008) 1.60
Socioeconomic status as a moderator between frailty and mortality at old ages. BMC Geriatr (2016) 1.41
Frailty and mortality among Chinese at advanced ages. J Gerontol B Psychol Sci Soc Sci (2009) 1.40
A frailty index to predict the mortality risk in a population of senior Mexican adults. BMC Geriatr (2009) 1.30
Accelerated accumulation of health deficits as a characteristic of aging. Exp Gerontol (2007) 1.29
Cumulative deficits and physiological indices as predictors of mortality and long life. J Gerontol A Biol Sci Med Sci (2008) 1.20
The frailty index in Europeans: association with age and mortality. Age Ageing (2012) 1.17
What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data. Mech Ageing Dev (2008) 1.06
Analysis of frailty and survival from late middle age in the Beijing Longitudinal Study of Aging. BMC Geriatr (2011) 1.03
A review of selected longitudinal studies on aging: past findings and future directions. J Am Geriatr Soc (2010) 1.03
Prevalence and outcomes of frailty in Korean elderly population: comparisons of a multidimensional frailty index with two phenotype models. PLoS One (2014) 1.00
Sex-specific health deterioration and mortality: the morbidity-mortality paradox over age and time. Exp Gerontol (2008) 0.96
Accumulation of non-traditional risk factors for coronary heart disease is associated with incident coronary heart disease hospitalization and death. PLoS One (2014) 0.94
Quantitative measures of healthy aging and biological age. Healthy Aging Res (2015) 0.91
Apolipoprotein E-polymorphism, frailty and mortality in older adults. J Cell Mol Med (2008) 0.90
Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits. Mech Ageing Dev (2011) 0.88
Changes in health status among participants of the Framingham Heart Study from the 1960s to the 1990s: application of an index of cumulative deficits. Ann Epidemiol (2008) 0.87
Association of healthy aging with parental longevity. Age (Dordr) (2012) 0.84
Sex differences in the limit to deficit accumulation in late middle-aged and older Chinese people: results from the Beijing Longitudinal Study of Aging. J Gerontol A Biol Sci Med Sci (2013) 0.82
Studying health histories of cancer: a new model connecting cancer incidence and survival. Math Biosci (2009) 0.82
Heterogeneity of Human Aging and Its Assessment. J Gerontol A Biol Sci Med Sci (2017) 0.78
Mortality deceleration and mortality selection: three unexpected implications of a simple model. Demography (2014) 0.76
The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age. Geroscience (2017) 0.75
Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci (2001) 42.21
Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci (2004) 12.46
Associations of subclinical cardiovascular disease with frailty. J Gerontol A Biol Sci Med Sci (2001) 5.09
Change in chronic disability from 1982 to 2004/2005 as measured by long-term changes in function and health in the U.S. elderly population. Proc Natl Acad Sci U S A (2006) 4.76
Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc (2005) 4.48
Accumulation of deficits as a proxy measure of aging. ScientificWorldJournal (2001) 4.47
Morbidity profiles of centenarians: survivors, delayers, and escapers. J Gerontol A Biol Sci Med Sci (2003) 3.67
Muscle strength and body mass index as long-term predictors of mortality in initially healthy men. J Gerontol A Biol Sci Med Sci (2000) 3.20
Midlife risk factors and healthy survival in men. JAMA (2006) 3.00
Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70. J Am Geriatr Soc (2006) 2.91
Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr (2002) 2.63
Frailty index as a measure of biological age in a Chinese population. J Gerontol A Biol Sci Med Sci (2005) 2.58
A conceptual framework of frailty: a review. J Gerontol A Biol Sci Med Sci (2002) 2.38
Sex differences in the risk of frailty for mortality independent of disability and chronic diseases. J Am Geriatr Soc (2005) 2.03
Changes with age in the distribution of a frailty index. Mech Ageing Dev (2004) 1.80
Limits to deficit accumulation in elderly people. Mech Ageing Dev (2006) 1.80
Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: results from analyses of the National Long Term Care Survey. Mech Ageing Dev (2006) 1.76
Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data. Mech Ageing Dev (2006) 1.74
The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol (2003) 1.58
Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity. Rejuvenation Res (2007) 1.53
Public health significance of the frailty index. Disabil Rehabil (2006) 1.47
Health decline, aging and mortality: how are they related? Biogerontology (2007) 1.45
APACHE II, data accuracy and outcome prediction. Anaesthesia (1998) 1.43
Just what defines frailty? J Am Geriatr Soc (2005) 1.40
Cancer in rodents: does it tell us about cancer in humans? Nat Rev Cancer (2005) 1.27
How individual age-associated changes may influence human morbidity and mortality patterns. Mech Ageing Dev (2001) 1.13
Molecular gerontology. J Inherit Metab Dis (2002) 1.01
Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J Am Geriatr Soc (2008) 2.94
Health and function of participants in the Long Life Family Study: A comparison with other cohorts. Aging (Albany NY) (2011) 1.74
Stochastic model for analysis of longitudinal data on aging and mortality. Math Biosci (2006) 1.61
Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity. Rejuvenation Res (2007) 1.53
A bivariate frailty model with a cure fraction for modeling familial correlations in diseases. Biometrics (2003) 1.46
Health decline, aging and mortality: how are they related? Biogerontology (2007) 1.45
Visualizing hidden heterogeneity in isogenic populations of C. elegans. Exp Gerontol (2006) 1.33
Accelerated accumulation of health deficits as a characteristic of aging. Exp Gerontol (2007) 1.29
Cancer in rodents: does it tell us about cancer in humans? Nat Rev Cancer (2005) 1.27
Stress resistance declines with age: analysis of data from a survival experiment with Drosophila melanogaster. Biogerontology (2004) 1.25
Insights on aging and exceptional longevity from longitudinal data: novel findings from the Framingham Heart Study. Age (Dordr) (2006) 1.24
Heritability estimates of endophenotypes of long and health life: the Long Life Family Study. J Gerontol A Biol Sci Med Sci (2010) 1.22
Cumulative deficits and physiological indices as predictors of mortality and long life. J Gerontol A Biol Sci Med Sci (2008) 1.20
Age trajectories of physiological indices in relation to healthy life course. Mech Ageing Dev (2011) 1.17
Insulin and longevity: antidiabetic biguanides as geroprotectors. Biogerontology (2003) 1.17
Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals. J Am Geriatr Soc (2007) 1.16
Joint influence of small-effect genetic variants on human longevity. Aging (Albany NY) (2010) 1.16
Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies. Mech Ageing Dev (2008) 1.10
The heritability of CHD mortality in danish twins after controlling for smoking and BMI. Twin Res Hum Genet (2005) 1.09
Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data. Biogerontology (2009) 1.07
Maintaining physiological state for exceptional survival: What is the normal level of blood glucose and does it change with age? Mech Ageing Dev (2009) 1.07
What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data. Mech Ageing Dev (2008) 1.06
The role of lipid-related genes, aging-related processes, and environment in healthspan. Aging Cell (2013) 1.05
New age patterns of survival improvement in Sweden: do they characterize changes in individual aging? Mech Ageing Dev (2002) 1.05
Genetic model for longitudinal studies of aging, health, and longevity and its potential application to incomplete data. J Theor Biol (2009) 1.04
Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan. Aging Cell (2011) 1.03
Model of hidden heterogeneity in longitudinal data. Theor Popul Biol (2007) 1.03
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects? Mech Ageing Dev (2005) 1.03
Individual aging and mortality rate: how are they related? Soc Biol (2003) 1.03
Association between APOE epsilon 2/epsilon 3/epsilon 4 polymorphism and disability severity in a national long-term care survey sample. Age Ageing (2008) 1.03
Leukocyte telomere length is associated with disability in older u.s. Population. J Am Geriatr Soc (2010) 1.02
"Predicting" parental longevity from offspring endophenotypes: data from the Long Life Family Study (LLFS). Mech Ageing Dev (2010) 1.01
Trade-offs between cancer and other diseases: do they exist and influence longevity? Rejuvenation Res (2010) 0.98
What fecundity patterns indicate about aging and longevity: insights from Drosophila studies. J Gerontol A Biol Sci Med Sci (2003) 0.98
Sex-specific health deterioration and mortality: the morbidity-mortality paradox over age and time. Exp Gerontol (2008) 0.96
Individual fecundity and senescence in Drosophila and medfly. J Gerontol A Biol Sci Med Sci (2005) 0.95
The accuracy of statistical estimates in genetic studies of aging can be significantly improved. Biogerontology (2006) 0.94
How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data. Front Genet (2013) 0.94
Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data. Biogerontology (2010) 0.94
Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice. Cancer Lett (2003) 0.93
A centenarian-only approach for assessing gene-gene interaction in human longevity. Eur J Hum Genet (2002) 0.92
Dynamic determinants of longevity and exceptional health. Curr Gerontol Geriatr Res (2010) 0.92
Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context. Mech Ageing Dev (2010) 0.92
A correlated frailty model with long-term survivors for estimating the heritability of breast cancer. Stat Med (2007) 0.91
The heritability of breast cancer: a Bayesian correlated frailty model applied to Swedish twins data. Twin Res (2004) 0.91
The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality? J Gerontol A Biol Sci Med Sci (2008) 0.90
Inter-chromosomal level of genome organization and longevity-related phenotypes in humans. Age (Dordr) (2012) 0.90
How genes influence life span: the biodemography of human survival. Rejuvenation Res (2012) 0.89
Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality. Rejuvenation Res (2012) 0.89
Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. Rejuvenation Res (2010) 0.89
Stressors and antistressors: how do they influence life span in HER-2/neu transgenic mice? Exp Gerontol (2004) 0.88
The heritability of cause-specific mortality: a correlated gamma-frailty model applied to mortality due to respiratory diseases in Danish twins born 1870-1930. Stat Med (2003) 0.88
Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men. J Am Geriatr Soc (2008) 0.88
Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits. Mech Ageing Dev (2011) 0.88