PubRank

William W Metcalf

Author PubWeight™ 80.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The genome of M. acetivorans reveals extensive metabolic and physiological diversity. Genome Res 2002 4.58
2 Genetic analysis of pigment biosynthesis in Xanthobacter autotrophicus Py2 using a new, highly efficient transposon mutagenesis system that is functional in a wide variety of bacteria. Arch Microbiol 2002 3.19
3 Development of a markerless genetic exchange method for Methanosarcina acetivorans C2A and its use in construction of new genetic tools for methanogenic archaea. Appl Environ Microbiol 2004 1.88
4 The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes. J Bacteriol 2006 1.79
5 Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nat Chem Biol 2007 1.72
6 Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation. Proc Natl Acad Sci U S A 2002 1.63
7 Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation. Mol Cell Proteomics 2006 1.57
8 Microbial metabolism of reduced phosphorus compounds. Annu Rev Microbiol 2007 1.55
9 An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis. Nature 2009 1.51
10 Anaerobic growth of Methanosarcina acetivorans C2A on carbon monoxide: an unusual way of life for a methanogenic archaeon. Proc Natl Acad Sci U S A 2004 1.50
11 Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736. Antimicrob Agents Chemother 2005 1.50
12 Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. Chem Biol 2006 1.47
13 Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. Chem Biol 2008 1.41
14 Two C-P lyase operons in Pseudomonas stutzeri and their roles in the oxidation of phosphonates, phosphite, and hypophosphite. J Bacteriol 2004 1.38
15 A new activity for an old enzyme: Escherichia coli bacterial alkaline phosphatase is a phosphite-dependent hydrogenase. Proc Natl Acad Sci U S A 2004 1.34
16 Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633. Chem Biol 2010 1.30
17 Directed mutagenesis and plasmid-based complementation in the methanogenic archaeon Methanosarcina acetivorans C2A demonstrated by genetic analysis of proline biosynthesis. J Bacteriol 2002 1.29
18 New methods for tightly regulated gene expression and highly efficient chromosomal integration of cloned genes for Methanosarcina species. Archaea 2008 1.27
19 Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes. BMC Genomics 2013 1.27
20 Genetic analysis of mch mutants in two Methanosarcina species demonstrates multiple roles for the methanopterin-dependent C-1 oxidation/reduction pathway and differences in H(2) metabolism between closely related species. Mol Microbiol 2005 1.26
21 Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc Natl Acad Sci U S A 2010 1.20
22 Characterization of a Methanosarcina acetivorans mutant unable to translate UAG as pyrrolysine. Mol Microbiol 2006 1.20
23 Biochemical, molecular, and genetic analyses of the acetone carboxylases from Xanthobacter autotrophicus strain Py2 and Rhodobacter capsulatus strain B10. J Bacteriol 2002 1.17
24 Molecular cloning and heterologous expression of the dehydrophos biosynthetic gene cluster. Chem Biol 2010 1.17
25 Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways. J Biol Chem 2008 1.17
26 Genetic technologies for Archaea. Curr Opin Microbiol 2005 1.14
27 Loss of the mtr operon in Methanosarcina blocks growth on methanol, but not methanogenesis, and reveals an unknown methanogenic pathway. Proc Natl Acad Sci U S A 2005 1.11
28 Diversity and abundance of phosphonate biosynthetic genes in nature. Proc Natl Acad Sci U S A 2013 1.08
29 Genetic, physiological and biochemical characterization of multiple methanol methyltransferase isozymes in Methanosarcina acetivorans C2A. Mol Microbiol 2005 1.07
30 Hydrogen is a preferred intermediate in the energy-conserving electron transport chain of Methanosarcina barkeri. Proc Natl Acad Sci U S A 2009 1.06
31 Distinct regulators control the expression of methanol methyltransferase isozymes in Methanosarcina acetivorans C2A. Mol Microbiol 2007 1.05
32 The htx and ptx operons of Pseudomonas stutzeri WM88 are new members of the pho regulon. J Bacteriol 2004 1.05
33 Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase. Mol Microbiol 2009 1.03
34 Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid. Angew Chem Int Ed Engl 2007 1.02
35 Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme. Angew Chem Int Ed Engl 2002 1.02
36 ITEP: an integrated toolkit for exploration of microbial pan-genomes. BMC Genomics 2014 1.02
37 A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria. J Proteome Res 2011 1.01
38 Differential regulation of the three methanol methyltransferase isozymes in Methanosarcina acetivorans C2A. J Bacteriol 2006 1.01
39 Genetic manipulation of Methanosarcina spp. Front Microbiol 2012 1.00
40 Differences in hydrogenase gene expression between Methanosarcina acetivorans and Methanosarcina barkeri. J Bacteriol 2009 0.98
41 Isolation and biochemical characterization of hypophosphite/2-oxoglutarate dioxygenase. A novel phosphorus-oxidizing enzyme from Psuedomonas stutzeri WM88. J Biol Chem 2002 0.98
42 Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species. Antimicrob Agents Chemother 2012 0.98
43 Top-down proteomics reveals novel protein forms expressed in Methanosarcina acetivorans. J Am Soc Mass Spectrom 2009 0.98
44 Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A. J Bacteriol 2011 0.97
45 Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase. Chem Biol 2011 0.95
46 Genetic analysis of the methanol- and methylamine-specific methyltransferase 2 genes of Methanosarcina acetivorans C2A. J Bacteriol 2008 0.95
47 Deciphering the late biosynthetic steps of antimalarial compound FR-900098. Chem Biol 2010 0.93
48 Mutagenesis of the C1 oxidation pathway in Methanosarcina barkeri: new insights into the Mtr/Mer bypass pathway. J Bacteriol 2008 0.93
49 Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster. Angew Chem Int Ed Engl 2013 0.92
50 Genetic and biochemical characterization of a pathway for the degradation of 2-aminoethylphosphonate in Sinorhizobium meliloti 1021. J Biol Chem 2011 0.91
51 Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo. Chem Biol 2011 0.91
52 Genetic diversity and horizontal transfer of genes involved in oxidation of reduced phosphorus compounds by Alcaligenes faecalis WM2072. Appl Environ Microbiol 2005 0.90
53 Development of genetic methods and construction of a chromosomal glnK1 mutant in Methanosarcina mazei strain Gö1. Mol Genet Genomics 2005 0.90
54 Identification and heterologous expression of genes involved in anaerobic dissimilatory phosphite oxidation by Desulfotignum phosphitoxidans. J Bacteriol 2010 0.90
55 Genome sequences of three tunicamycin-producing Streptomyces Strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396. J Bacteriol 2011 0.89
56 A vacuum-vortex technique for preparation of anoxic solutions or liquid culture media in small volumes for cultivating methanogens or other strict anaerobes. Anaerobe 2009 0.88
57 Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways. J Ind Microbiol Biotechnol 2013 0.88
58 Regulation of putative methyl-sulphide methyltransferases in Methanosarcina acetivorans C2A. Mol Microbiol 2009 0.88
59 Physiology and posttranscriptional regulation of methanol:coenzyme M methyltransferase isozymes in Methanosarcina acetivorans C2A. J Bacteriol 2009 0.88
60 The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica. Antimicrob Agents Chemother 2011 0.86
61 Assignment of the [4Fe-4S] clusters of Ech hydrogenase from Methanosarcina barkeri to individual subunits via the characterization of site-directed mutants. FEBS J 2005 0.86
62 Discovery of the antibiotic phosacetamycin via a new mass spectrometry-based method for phosphonic acid detection. ACS Chem Biol 2013 0.84
63 Class I and class II lysyl-tRNA synthetase mutants and the genetic encoding of pyrrolysine in Methanosarcina spp. Mol Microbiol 2007 0.83
64 Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways. J Ind Microbiol Biotechnol 2013 0.82
65 Genomically and biochemically accurate metabolic reconstruction of Methanosarcina barkeri Fusaro, iMG746. Biotechnol J 2013 0.82
66 Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase. Biochemistry 2012 0.82
67 Uptake of glycerol-2-phosphate via the ugp-encoded transporter in Escherichia coli K-12. J Bacteriol 2009 0.81
68 Cyanohydrin phosphonate natural product from Streptomyces regensis. J Nat Prod 2014 0.81
69 Purification and characterization of phosphonoglycans from Glycomyces sp. strain NRRL B-16210 and Stackebrandtia nassauensis NRRL B-16338. J Bacteriol 2014 0.80