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1
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Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.
|
Mol Cell Biol
|
2003
|
3.45
|
|
2
|
Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.
|
Immunity
|
2009
|
2.44
|
|
3
|
Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2.
|
Nat Genet
|
2003
|
2.43
|
|
4
|
Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab.
|
Blood
|
2008
|
2.16
|
|
5
|
Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.
|
Science
|
2008
|
2.10
|
|
6
|
Definitive-like erythroid cells derived from human embryonic stem cells coexpress high levels of embryonic and fetal globins with little or no adult globin.
|
Blood
|
2006
|
1.95
|
|
7
|
Combinatorial and distinct roles of α₅ and α₄ integrins in stress erythropoiesis in mice.
|
Blood
|
2010
|
1.72
|
|
8
|
In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients.
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Blood Cells Mol Dis
|
2002
|
1.70
|
|
9
|
MicroRNA expression dynamics during murine and human erythroid differentiation.
|
Exp Hematol
|
2007
|
1.67
|
|
10
|
Thrombopoietin expands hematopoietic stem cells after transplantation.
|
J Clin Invest
|
2002
|
1.63
|
|
11
|
Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.
|
Blood
|
2002
|
1.60
|
|
12
|
Functional disruption of alpha4 integrin mobilizes bone marrow-derived endothelial progenitors and augments ischemic neovascularization.
|
J Exp Med
|
2006
|
1.56
|
|
13
|
Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.
|
Blood
|
2005
|
1.37
|
|
14
|
Trisomy correction in Down syndrome induced pluripotent stem cells.
|
Cell Stem Cell
|
2012
|
1.35
|
|
15
|
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
|
Cancer Res
|
2010
|
1.34
|
|
16
|
Lack of alpha4 integrin expression in stem cells restricts competitive function and self-renewal activity.
|
Blood
|
2005
|
1.32
|
|
17
|
Transduction of human NOD/SCID-repopulating cells with both lymphoid and myeloid potential by foamy virus vectors.
|
Proc Natl Acad Sci U S A
|
2002
|
1.32
|
|
18
|
VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin.
|
Blood
|
2005
|
1.30
|
|
19
|
Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.
|
Exp Hematol
|
2009
|
1.26
|
|
20
|
Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.
|
Blood
|
2008
|
1.20
|
|
21
|
Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5.
|
Mol Cell Biol
|
2007
|
1.19
|
|
22
|
Globin phenotype of erythroid cells derived from human induced pluripotent stem cells.
|
Blood
|
2010
|
1.19
|
|
23
|
Diverse hematopoietic potentials of five human embryonic stem cell lines.
|
Exp Cell Res
|
2008
|
1.17
|
|
24
|
Concurrent blockade of alpha4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization.
|
Stem Cells
|
2009
|
1.15
|
|
25
|
Sustained alterations in biodistribution of stem/progenitor cells in Tie2Cre+ alpha4(f/f) mice are hematopoietic cell autonomous.
|
Blood
|
2006
|
1.12
|
|
26
|
PTX-sensitive signals in bone marrow homing of fetal and adult hematopoietic progenitor cells.
|
Blood
|
2004
|
1.10
|
|
27
|
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.
|
Blood
|
2013
|
1.08
|
|
28
|
Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model.
|
PLoS One
|
2012
|
1.08
|
|
29
|
The potential of stem cells as an in vitro source of red blood cells for transfusion.
|
Cell Stem Cell
|
2012
|
1.06
|
|
30
|
Hematopoietic progenitor cells (HPC) from mobilized peripheral blood display enhanced migration and marrow homing compared to steady-state bone marrow HPC.
|
Exp Hematol
|
2007
|
1.05
|
|
31
|
Hematopoietic stem cell mobilization for gene therapy of adult patients with severe β-thalassemia: results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects.
|
Mol Ther
|
2011
|
1.03
|
|
32
|
Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1 low mouse model of the disease.
|
Exp Hematol
|
2008
|
1.02
|
|
33
|
Alpha4 and beta2 integrins have nonredundant roles for asthma development, but for optimal allergen sensitization only alpha4 is critical.
|
Exp Hematol
|
2007
|
0.98
|
|
34
|
A capsid-modified helper-dependent adenovirus vector containing the beta-globin locus control region displays a nonrandom integration pattern and allows stable, erythroid-specific gene expression.
|
J Virol
|
2005
|
0.98
|
|
35
|
On the adaptation of endosteal stem cell niche function in response to stress.
|
Blood
|
2009
|
0.97
|
|
36
|
VCAM-1 ablation in nonhematopoietic cells in MxCre+ VCAM-1f/f mice is variable and dictates their phenotype.
|
Exp Hematol
|
2007
|
0.96
|
|
37
|
Unique and redundant roles of alpha4 and beta2 integrins in kinetics of recruitment of lymphoid vs myeloid cell subsets to the inflamed peritoneum revealed by studies of genetically deficient mice.
|
Exp Hematol
|
2007
|
0.96
|
|
38
|
Megakaryocytes require thrombospondin-2 for normal platelet formation and function.
|
Blood
|
2003
|
0.95
|
|
39
|
Transcriptional regulation of miR-10a/b by TWIST-1 in myelodysplastic syndromes.
|
Haematologica
|
2012
|
0.95
|
|
40
|
Hematopoietic stem cell mobilization for gene therapy: superior mobilization by the combination of granulocyte-colony stimulating factor plus plerixafor in patients with β-thalassemia major.
|
Hum Gene Ther
|
2013
|
0.93
|
|
41
|
The transcription factor IRF3 triggers "defensive suicide" necrosis in response to viral and bacterial pathogens.
|
Cell Rep
|
2013
|
0.93
|
|
42
|
Transgenic Cre expression mice for generation of erythroid-specific gene alterations.
|
Genesis
|
2004
|
0.93
|
|
43
|
Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models.
|
Exp Hematol
|
2009
|
0.92
|
|
44
|
JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells.
|
EMBO J
|
2002
|
0.89
|
|
45
|
Distinct changes in adult lymphopoiesis in Rag2-/- mice fully reconstituted by alpha4-deficient adult bone marrow cells.
|
Exp Hematol
|
2008
|
0.88
|
|
46
|
Mobilization of hematopoietic stem/progenitor cells: general principles and molecular mechanisms.
|
Methods Mol Biol
|
2012
|
0.88
|
|
47
|
Erythroid cells generated in the absence of specific β1-integrin heterodimers accumulate reactive oxygen species at homeostasis and are unable to mount effective antioxidant defenses.
|
Haematologica
|
2013
|
0.87
|
|
48
|
Generation and characterization of erythroid cells from human embryonic stem cells and induced pluripotent stem cells: an overview.
|
Stem Cells Int
|
2011
|
0.85
|
|
49
|
Anatomical compartments modify the response of human hematopoietic cells to a mitogenic signal.
|
Stem Cells
|
2005
|
0.85
|
|
50
|
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures.
|
Blood Cells Mol Dis
|
2003
|
0.85
|
|
51
|
Epigenetic modifications and chromosome conformations of the beta globin locus throughout development.
|
Stem Cell Rev
|
2013
|
0.82
|
|
52
|
MicroRNAs: Allies or foes in erythropoiesis?
|
J Cell Physiol
|
2012
|
0.81
|
|
53
|
Cells with hemopoietic potential residing in muscle are itinerant bone marrow-derived cells.
|
Exp Hematol
|
2002
|
0.81
|
|
54
|
The p67 laminin receptor identifies human erythroid progenitor and precursor cells and is functionally important for their bone marrow lodgment.
|
Blood
|
2006
|
0.79
|
|
55
|
Superior long-term repopulating capacity of G-CSF+plerixafor-mobilized blood: implications for stem cell gene therapy by studies in the Hbb(th-3) mouse model.
|
Hum Gene Ther Methods
|
2014
|
0.79
|
|
56
|
Long-term functional impairment of hemopoietic progenitor cells engineered to express the S1 catalytic subunit of pertussis toxin.
|
Exp Hematol
|
2005
|
0.79
|
|
57
|
Blockade of alpha6-integrin reveals diversity in homing patterns among human, baboon, and murine cells.
|
Stem Cells Dev
|
2009
|
0.78
|
|
58
|
Modeling promising nonmyeloablative conditioning regimens in nonhuman primates.
|
Hum Gene Ther
|
2014
|
0.77
|
|
59
|
Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection.
|
Immunity
|
2015
|
0.77
|
|
60
|
Bone marrow-derived CD45+ and CD45- cells reside in skeletal muscle.
|
Blood Cells Mol Dis
|
2002
|
0.76
|
|
61
|
Functional consequences of perturbed CXCL12 signal processing: analyses of immature hematopoiesis in GRK6-deficient mice.
|
Stem Cells Dev
|
2014
|
0.76
|
|
62
|
Vagrant stem cells draft their gene companions.
|
Cell Stem Cell
|
2010
|
0.75
|
|
63
|
Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny.
|
Exp Hematol
|
2013
|
0.75
|
|
64
|
Is the post-transplantation treatment with AMD beneficial?
|
Blood Cells Mol Dis
|
2012
|
0.75
|
|
65
|
β-Thalassemia due to intronic LINE-1 insertion in the β-globin gene (HBB): molecular mechanisms underlying reduced transcript levels of the β-globin(L1) allele.
|
Hum Mutat
|
2013
|
0.75
|