Published in Circ Res on June 07, 2007
Sp1 phosphorylation and its regulation of gene transcription. Mol Cell Biol (2009) 1.91
Hydrogen peroxide sensing, signaling and regulation of transcription factors. Redox Biol (2014) 1.54
Yin Yang 1 regulates the transcriptional activity of androgen receptor. Oncogene (2009) 1.15
Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition. Arterioscler Thromb Vasc Biol (2011) 1.12
Yin Yang 1: a multifaceted protein beyond a transcription factor. Transcription (2012) 1.08
Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells. J Biol Chem (2011) 1.03
Quantitative trait locus analysis of neointimal formation in an intercross between C57BL/6 and C3H/HeJ apolipoprotein E-deficient mice. Circ Cardiovasc Genet (2009) 1.02
The oncogenic role of Yin Yang 1. Crit Rev Oncog (2011) 1.02
Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. Am J Pathol (2012) 0.98
Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1. Nucleic Acids Res (2011) 0.97
c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins. J Biol Chem (2009) 0.91
The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1). Arterioscler Thromb Vasc Biol (2011) 0.84
Resistin promotes the expression of vascular endothelial growth factor in ovary carcinoma cells. Int J Mol Sci (2013) 0.83
Heme Oxygenases in Cardiovascular Health and Disease. Physiol Rev (2016) 0.82
Berberine represses DAXX gene transcription and induces cancer cell apoptosis. Lab Invest (2013) 0.81
DNAzymes and cardiovascular disease. Br J Pharmacol (2008) 0.80
Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res (2015) 0.79
Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expression. Genes Cancer (2014) 0.76
Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53. J Immunol (2016) 0.76
The balance of power: the law of Yin and Yang in smooth muscle cell fate. Is YY1 a vascular protector? Circ Res (2007) 0.75
Coordinated Transcriptional Control of Adipocyte Triglyceride Lipase (Atgl) by transcription factors Sp1 and PPARγ during Adipocyte Differentiation. J Biol Chem (2017) 0.75
Randomized trial of primary PCI with or without routine manual thrombectomy. N Engl J Med (2015) 7.83
A promoter-level mammalian expression atlas. Nature (2014) 6.25
DNAzyme targeting c-jun suppresses skin cancer growth. Sci Transl Med (2012) 3.09
Role of angiogenesis in cardiovascular disease: a critical appraisal. Circulation (2005) 2.13
Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth. Nat Med (2003) 2.03
Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents. J Natl Cancer Inst (2004) 2.00
Magnetic tagging increases delivery of circulating progenitors in vascular injury. JACC Cardiovasc Interv (2009) 1.94
Sp1 phosphorylation and its regulation of gene transcription. Mol Cell Biol (2009) 1.91
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells. Traffic (2006) 1.78
Angiogenesis-dependent and independent phases of intimal hyperplasia. Circulation (2004) 1.71
Correlation of increased vascular endothelial growth factor with neovascularization and permeability in ischemic central vein occlusion. Arch Ophthalmol (2002) 1.67
B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions. Circ Res (2011) 1.67
Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque. Circ Res (2008) 1.65
Coronary in-stent restenosis: current status and future strategies. J Am Coll Cardiol (2002) 1.64
Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signaling. J Biol Chem (2006) 1.60
Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease. J Leukoc Biol (2013) 1.57
Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR. Cancer Cell (2011) 1.56
Ezetimibe improves liver steatosis and insulin resistance in obese rat model of metabolic syndrome. FEBS Lett (2007) 1.55
Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER). Lancet (2013) 1.50
Involvement of c-jun in human liposarcoma growth: supporting data from clinical immunohistochemistry and DNAzyme efficacy. Cancer Biol Ther (2008) 1.48
VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation. Mol Biol Cell (2011) 1.47
Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Mol Cell Biol (2003) 1.44
Repression of PDGF-R-α after cellular injury involves TNF-α, formation of a c-Fos-YY1 complex, and negative regulation by HDAC. Am J Physiol Cell Physiol (2012) 1.39
Intravascular ultrasound determinants of future coronary stent thrombosis. Am J Cardiol (2008) 1.38
Percutaneous coronary intervention and 30-day mortality: the British Columbia PCI risk score. Catheter Cardiovasc Interv (2009) 1.37
Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis. Traffic (2010) 1.36
Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol Cell Biol (2011) 1.30
Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma. J Natl Cancer Inst (2003) 1.26
Placental growth factor promotes atherosclerotic intimal thickening and macrophage accumulation. Circulation (2005) 1.23
Evaluation of NHMRC funded research completed in 1992, 1997 and 2003: gains in knowledge, health and wealth. Med J Aust (2006) 1.21
Cytotoxic and proinflammatory CD8+ T lymphocytes promote development of vulnerable atherosclerotic plaques in apoE-deficient mice. Circulation (2013) 1.21
ERK, JNK, and p38 MAP kinases differentially regulate proliferation and migration of phenotypically distinct smooth muscle cell subtypes. J Cell Biochem (2003) 1.20
Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase. Cell Signal (2008) 1.20
Psychological stress activates interleukin-1beta gene expression in human mononuclear cells. Brain Behav Immun (2005) 1.17
Early growth response-1 regulates angiopoietin-1-induced endothelial cell proliferation, migration, and differentiation. Arterioscler Thromb Vasc Biol (2008) 1.16
Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance. Am J Physiol Endocrinol Metab (2009) 1.15
Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis. Circulation (2012) 1.15
Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas. Biochem J (2011) 1.14
Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun. Nat Biotechnol (2006) 1.13
Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation. PLoS One (2012) 1.13
Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway. EMBO Rep (2008) 1.12
Inhibition of human breast carcinoma proliferation, migration, chemoinvasion and solid tumour growth by DNAzymes targeting the zinc finger transcription factor EGR-1. Nucleic Acids Res (2004) 1.11
Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13. Blood (2003) 1.10
Cytochrome b558-dependent NAD(P)H oxidase-phox units in smooth muscle and macrophages of atherosclerotic lesions. Arterioscler Thromb Vasc Biol (2002) 1.10
TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor. J Biol Chem (2008) 1.09
Heat shock protein 27: its potential role in vascular disease. Int J Exp Pathol (2006) 1.09
Macrophage migration inhibitory factor increases leukocyte-endothelial interactions in human endothelial cells via promotion of expression of adhesion molecules. J Immunol (2010) 1.09
Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey. Med J Aust (2008) 1.06
Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice. J Biol Chem (2004) 1.05
Inducible platelet-derived growth factor D-chain expression by angiotensin II and hydrogen peroxide involves transcriptional regulation by Ets-1 and Sp1. Blood (2005) 1.05
Indoxyl sulfate induces leukocyte-endothelial interactions through up-regulation of E-selectin. J Biol Chem (2010) 1.03
Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells. J Biol Chem (2005) 1.02
p130Cas: a key signalling node in health and disease. Cell Signal (2012) 1.01
Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation. J Biol Chem (2003) 1.01
Ets-1 stimulates platelet-derived growth factor A-chain gene transcription and vascular smooth muscle cell growth via cooperative interactions with Sp1. Circ Res (2004) 1.01
Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am J Pathol (2007) 1.01
DNAzyme technology and cancer therapy: cleave and let die. Mol Cancer Ther (2008) 1.01
Vascular endothelial growth factor regulates stanniocalcin-1 expression via neuropilin-1-dependent regulation of KDR and synergism with fibroblast growth factor-2. Cell Signal (2007) 1.00
Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells. Biochem J (2010) 0.99
Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. Diabetes (2011) 0.99
A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer. Mol Cancer Res (2009) 0.99
NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter. EMBO J (2002) 0.98
Retracted Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1. J Biol Chem (2002) 0.98
The von Willebrand factor-reducing activity of thrombospondin-1 is located in the calcium-binding/C-terminal sequence and requires a free thiol at position 974. Blood (2002) 0.97
TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 phosphorylation-, and NFkappaB-dependent manner. Circ Res (2010) 0.97
Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1. J Biol Chem (2003) 0.97
Efficacy of recombinant annexin 2 for fibrinolytic therapy in a rat embolic stroke model: a magnetic resonance imaging study. Brain Res (2007) 0.96
Natural killer (NK) cells augment atherosclerosis by cytotoxic-dependent mechanisms. Cardiovasc Res (2014) 0.96
Estrogen receptor polymorphisms: significance to human physiology, disease and therapy. Recent Pat DNA Gene Seq (2009) 0.96
Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1. J Biol Chem (2004) 0.95
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells. Arterioscler Thromb Vasc Biol (2009) 0.95
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1. Circ Res (2008) 0.95
Catalytic antisense DNA molecules targeting Egr-1 inhibit neointima formation following permanent ligation of rat common carotid arteries. Thromb Haemost (2002) 0.95
Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer. Oncotarget (2013) 0.94
Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting. Arterioscler Thromb Vasc Biol (2002) 0.94
Albendazole inhibits endothelial cell migration, tube formation, vasopermeability, VEGF receptor-2 expression and suppresses retinal neovascularization in ROP model of angiogenesis. Biochem Biophys Res Commun (2010) 0.94
Emerging therapeutic approaches in the management of retinal angiogenesis and edema. J Mol Med (Berl) (2010) 0.93
Rat models of myocardial infarction. Pathogenetic insights and clinical relevance. Thromb Haemost (2006) 0.93
PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL. Endocrinology (2010) 0.92
Inhibition of fibroblast growth factor receptor signaling attenuates atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2006) 0.92
Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2014) 0.92
c-Jun regulates shear- and injury-inducible Egr-1 expression, vein graft stenosis after autologous end-to-side transplantation in rabbits, and intimal hyperplasia in human saphenous veins. J Biol Chem (2009) 0.91
BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE(-/-) mice. PLoS One (2013) 0.91
Anti-heat shock protein-27 (Hsp-27) antibody levels in patients with chest pain: association with established cardiovascular risk factors. Clin Chim Acta (2008) 0.91