PubRank

Jane A Grasby

Author PubWeight™ 25.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell 2011 2.44
2 The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis. J Biol Chem 2009 1.27
3 Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. J Biol Chem 2008 1.16
4 Substrate recognition and catalysis by flap endonucleases and related enzymes. Biochem Soc Trans 2010 1.10
5 Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease. EMBO J 2003 1.07
6 Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends. Nucleic Acids Res 2012 1.06
7 Determination of the catalytic parameters of the N-terminal half of Escherichia coli ribonuclease E and the identification of critical functional groups in RNA substrates. J Biol Chem 2003 1.01
8 The RuvABC resolvasome. Eur J Biochem 2002 0.98
9 Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease. J Mol Biol 2007 0.97
10 Brønsted analysis and rate-limiting steps for the T5 flap endonuclease catalyzed hydrolysis of exonucleolytic substrates. Biochemistry 2010 0.97
11 Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding. Proc Natl Acad Sci U S A 2002 0.96
12 Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities. Nucleic Acids Res 2004 0.96
13 Holliday junction binding and processing by the RuvA protein of Mycoplasma pneumoniae. Eur J Biochem 2002 0.95
14 A conserved tyrosine residue aids ternary complex formation, but not catalysis, in phage T5 flap endonuclease. J Mol Biol 2002 0.91
15 Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions. J Biol Chem 2011 0.89
16 Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-π interactions. Proc Natl Acad Sci U S A 2012 0.89
17 The role of magnesium ions and 2'-hydroxyl groups in the VS ribozyme-substrate interaction. J Mol Biol 2002 0.89
18 Observation of unpaired substrate DNA in the flap endonuclease-1 active site. Nucleic Acids Res 2013 0.88
19 Interstrand disulfide crosslinking of DNA bases supports a double nucleotide unpairing mechanism for flap endonucleases. Chem Commun (Camb) 2012 0.86
20 The pH-dependence of the Escherichia coli RNase HII-catalysed reaction suggests that an active site carboxylate group participates directly in catalysis. J Mol Biol 2007 0.85
21 RNA footprinting analysis using ion pair reverse phase liquid chromatography. RNA 2002 0.82
22 Proline scanning mutagenesis reveals a role for the flap endonuclease-1 helical cap in substrate unpairing. J Biol Chem 2013 0.79
23 Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry. Nucleic Acids Res 2014 0.79
24 Synthesis of oligodeoxyribonucleotides containing a conformationally-locked anti analogue of O6-methyl-2'-deoxyguanosine and their recognition by MGMT and Atl1. Chem Commun (Camb) 2012 0.78
25 The role of phosphate groups in the VS ribozyme-substrate interaction. Nucleic Acids Res 2004 0.78
26 The synthesis and properties of oligoribonucleotide-spermine conjugates. Org Biomol Chem 2004 0.77
27 Human Exonuclease 1 Threads 5'-Flap Substrates Through its Helical Arch. Biochemistry 2017 0.75