Published in Mol Carcinog on August 01, 2007
Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization. Cell Cycle (2009) 1.49
Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis. Exp Dermatol (2013) 1.39
Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids (2011) 1.03
Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. Biochem J (2012) 0.85
Small molecule inhibitors of histone acetyltransferase Tip60. Bioorg Chem (2010) 0.85
Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines. Cancer Growth Metastasis (2015) 0.84
ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma. Cancer Res (2008) 1.47
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion. Cancer Immunol Immunother (2010) 1.04
Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors. Cancer Res (2002) 1.03
Elevated levels of polyamines alter chromatin in murine skin and tumors without global changes in nucleosome acetylation. Exp Cell Res (2003) 0.94
A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development. Carcinogenesis (2011) 0.93
Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment. Cancer Immunol Res (2013) 0.88
Comparison of Comet assay dose-response for ethyl methanesulfonate using freshly prepared versus cryopreserved tissues. Environ Mol Mutagen (2011) 0.88
Tip60 protein isoforms and altered function in skin and tumors that overexpress ornithine decarboxylase. Cancer Res (2006) 0.87
Use of dabigatran etexilate to reduce breast cancer progression. Cancer Biol Ther (2010) 0.86
Elevated epidermal ornithine decarboxylase activity suppresses contact hypersensitivity. J Invest Dermatol (2010) 0.85
Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes. J Invest Dermatol (2005) 0.83
B23 is a downstream target of polyamine-modulated CK2. Mol Cell Biochem (2005) 0.82
Interaction between DNA Polymerase β and BRCA1. PLoS One (2013) 0.82
Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes. Cancer Res (2008) 0.80
A novel protein kinase CK2 substrate indicates CK2 is not directly stimulated by polyamines in vivo. Biochemistry (2006) 0.79
No increases in biomarkers of genetic damage or pathological changes in heart and brain tissues in male rats administered methylphenidate hydrochloride (Ritalin) for 28 days. Environ Mol Mutagen (2010) 0.78
Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites. Amino Acids (2013) 0.78
Development of polyamine transport ligands with improved metabolic stability and selectivity against specific human cancers. J Med Chem (2013) 0.76
Differential genotoxicity of acrylamide in the micronucleus and Pig-a gene mutation assays in F344 rats and B6C3F1 mice. Mutagenesis (2016) 0.75
Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice. Carcinogenesis (2004) 0.75