Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine.
|
J Clin Oncol
|
2007
|
6.68
|
2
|
New common variants affecting susceptibility to basal cell carcinoma.
|
Nat Genet
|
2009
|
4.15
|
3
|
High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.
|
PLoS One
|
2009
|
3.10
|
4
|
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.
|
J Exp Med
|
2002
|
3.02
|
5
|
Tumor-released microvesicles as vehicles of immunosuppression.
|
Cancer Res
|
2007
|
2.80
|
6
|
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells.
|
Cancer Res
|
2006
|
2.77
|
7
|
Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes.
|
Cancer Res
|
2006
|
2.61
|
8
|
Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings.
|
J Clin Oncol
|
2002
|
2.57
|
9
|
Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers.
|
Clin Cancer Res
|
2011
|
2.44
|
10
|
Defining the critical hurdles in cancer immunotherapy.
|
J Transl Med
|
2011
|
2.32
|
11
|
Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial.
|
Lancet Oncol
|
2012
|
2.03
|
12
|
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.
|
J Natl Cancer Inst
|
2004
|
2.02
|
13
|
Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape.
|
Gastroenterology
|
2005
|
2.00
|
14
|
Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients.
|
Cancer Immunol Immunother
|
2011
|
1.94
|
15
|
A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".
|
J Transl Med
|
2008
|
1.77
|
16
|
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.
|
Int J Cancer
|
2010
|
1.58
|
17
|
Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going?
|
J Natl Cancer Inst
|
2002
|
1.56
|
18
|
NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients.
|
Clin Cancer Res
|
2007
|
1.50
|
19
|
Cutaneous melanoma in childhood and adolescence shows frequent loss of INK4A and gain of KIT.
|
J Invest Dermatol
|
2009
|
1.48
|
20
|
Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer.
|
Clin Cancer Res
|
2003
|
1.46
|
21
|
Recent advances on the role of tumor exosomes in immunosuppression and disease progression.
|
Semin Cancer Biol
|
2012
|
1.46
|
22
|
Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy.
|
J Cell Physiol
|
2012
|
1.45
|
23
|
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes.
|
Int J Cancer
|
2012
|
1.45
|
24
|
Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.
|
Cancer Res
|
2012
|
1.41
|
25
|
LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites.
|
J Immunol
|
2010
|
1.37
|
26
|
Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells.
|
J Invest Dermatol
|
2010
|
1.35
|
27
|
Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.
|
J Transl Med
|
2009
|
1.31
|
28
|
Immune surveillance properties of human NK cell-derived exosomes.
|
J Immunol
|
2012
|
1.26
|
29
|
Identification of MET and SRC activation in melanoma cell lines showing primary resistance to PLX4032.
|
Neoplasia
|
2011
|
1.26
|
30
|
Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells.
|
Cancer Res
|
2005
|
1.24
|
31
|
IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells.
|
Blood
|
2004
|
1.22
|
32
|
Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer.
|
Cancer Immunol Immunother
|
2003
|
1.20
|
33
|
A variant in FTO shows association with melanoma risk not due to BMI.
|
Nat Genet
|
2013
|
1.17
|
34
|
A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-alpha in metastatic melanoma patients.
|
Cancer Immunol Immunother
|
2005
|
1.17
|
35
|
Potent phagocytic activity discriminates metastatic and primary human malignant melanomas: a key role of ezrin.
|
Lab Invest
|
2003
|
1.17
|
36
|
Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides.
|
Clin Cancer Res
|
2012
|
1.15
|
37
|
Proton dynamics in cancer.
|
J Transl Med
|
2010
|
1.14
|
38
|
More insights into the immunosuppressive potential of tumor exosomes.
|
J Transl Med
|
2008
|
1.14
|
39
|
CCN3/nephroblastoma overexpressed matricellular protein regulates integrin expression, adhesion, and dissemination in melanoma.
|
Cancer Res
|
2008
|
1.14
|
40
|
Melanoma immunology: past, present and future.
|
Curr Opin Oncol
|
2007
|
1.07
|
41
|
The apoptosis inhibitor protein survivin induces tumor-specific CD8+ and CD4+ T cells in colorectal cancer patients.
|
Cancer Res
|
2003
|
1.06
|
42
|
Detection of mutated BRAFV600E variant in circulating DNA of stage III-IV melanoma patients.
|
Int J Cancer
|
2007
|
1.06
|
43
|
Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.
|
Cancer Res
|
2006
|
1.06
|
44
|
Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators.
|
J Leukoc Biol
|
2005
|
1.05
|
45
|
Frequency of circulating Tregs with demethylated FOXP3 intron 1 in melanoma patients receiving tumor vaccines and potentially Treg-depleting agents.
|
Clin Cancer Res
|
2010
|
1.03
|
46
|
Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010".
|
J Transl Med
|
2011
|
1.02
|
47
|
DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis.
|
Int J Cancer
|
2005
|
1.01
|
48
|
Immunotherapy of melanoma.
|
Semin Cancer Biol
|
2003
|
1.01
|
49
|
Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens.
|
J Immunol
|
2004
|
1.01
|
50
|
Soluble human LAG-3 molecule amplifies the in vitro generation of type 1 tumor-specific immunity.
|
Cancer Res
|
2006
|
0.95
|
51
|
Multipeptide vaccination in cancer patients.
|
Expert Opin Biol Ther
|
2009
|
0.94
|
52
|
T-cell response to unique and shared antigens and vaccination of cancer patients.
|
Cancer Immun
|
2002
|
0.94
|
53
|
Antigen-specific immunity in neuroblastoma patients: antibody and T-cell recognition of NY-ESO-1 tumor antigen.
|
Cancer Res
|
2003
|
0.93
|
54
|
Universal and stemness-related tumor antigens: potential use in cancer immunotherapy.
|
Clin Cancer Res
|
2007
|
0.93
|
55
|
T cell responses against tumor associated antigens and prognosis in colorectal cancer patients.
|
J Transl Med
|
2005
|
0.92
|
56
|
Human plasmacytoid dendritic cells interact with gp96 via CD91 and regulate inflammatory responses.
|
J Immunol
|
2008
|
0.92
|
57
|
Molecular and functional bases of self-antigen recognition in long-term persistent melanocyte-specific CD8+ T cells in one vitiligo patient.
|
J Invest Dermatol
|
2003
|
0.91
|
58
|
Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice.
|
Cancer Res
|
2004
|
0.90
|
59
|
Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression.
|
Cancer Res
|
2014
|
0.88
|
60
|
Modified peptides in anti-cancer vaccines: are we eventually improving anti-tumour immunity?
|
Cancer Immunol Immunother
|
2008
|
0.87
|
61
|
Heat shock proteins and their use as anticancer vaccines.
|
Clin Cancer Res
|
2004
|
0.87
|
62
|
Adoptive transfer of an anti-MART-1(27-35)-specific CD8+ T cell clone leads to immunoselection of human melanoma antigen-loss variants in SCID mice.
|
Eur J Immunol
|
2003
|
0.86
|
63
|
Class I HLA folding and antigen presentation in beta 2-microglobulin-defective Daudi cells.
|
J Immunol
|
2009
|
0.85
|
64
|
Low TCR avidity and lack of tumor cell recognition in CD8(+) T cells primed with the CEA-analogue CAP1-6D peptide.
|
Cancer Immunol Immunother
|
2007
|
0.85
|
65
|
Vaccination therapy in prostate cancer.
|
Cancer Immunol Immunother
|
2006
|
0.85
|
66
|
The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors.
|
Oncoimmunology
|
2013
|
0.84
|
67
|
Natural killer and NK-Like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96.
|
Cancer Res
|
2005
|
0.84
|
68
|
Identification of a mutated receptor-like protein tyrosine phosphatase kappa as a novel, class II HLA-restricted melanoma antigen.
|
J Immunol
|
2003
|
0.84
|
69
|
Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation.
|
J Immunol
|
2008
|
0.83
|
70
|
Heat shock proteins gp96 as immunogens in cancer patients.
|
Int J Hyperthermia
|
2006
|
0.83
|
71
|
Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response.
|
Cancer Immunol Immunother
|
2013
|
0.82
|
72
|
HLA-A*0201-restricted CEA-derived peptide CAP1 is not a suitable target for T-cell-based immunotherapy.
|
J Immunother
|
2010
|
0.82
|
73
|
Suboptimal activation of CD8(+) T cells by melanoma-derived altered peptide ligands: role of Melan-A/MART-1 optimized analogues.
|
Cancer Res
|
2003
|
0.82
|
74
|
Modulation of the myeloid compartment of the immune system by angiogenic- and kinase inhibitor-targeted anti-cancer therapies.
|
Cancer Immunol Immunother
|
2014
|
0.80
|
75
|
Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.
|
Eur J Cancer
|
2005
|
0.80
|
76
|
A large de novo 9p21.3 deletion in a girl affected by astrocytoma and multiple melanoma.
|
BMC Med Genet
|
2014
|
0.79
|
77
|
Chemokine receptor 7, a new player in regulating apoptosis of CD8+ T cells in cancer patients.
|
Clin Cancer Res
|
2005
|
0.79
|
78
|
Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma.
|
J Transl Med
|
2013
|
0.79
|
79
|
Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1.
|
Clin Cancer Res
|
2008
|
0.79
|
80
|
Promoter methylation of aminopeptidase N/CD13 in malignant melanoma.
|
Carcinogenesis
|
2012
|
0.78
|
81
|
Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatment.
|
Expert Rev Mol Diagn
|
2014
|
0.78
|
82
|
Vaccination: role in metastatic melanoma.
|
Expert Rev Anticancer Ther
|
2006
|
0.77
|
83
|
Spheres of influence in cancer stem cell biology.
|
J Invest Dermatol
|
2010
|
0.76
|
84
|
Don't run before you can walk.
|
Nat Rev Urol
|
2012
|
0.75
|
85
|
Exploiting liver immunity for the prevention of hepatic metastases.
|
J Hepatol
|
2010
|
0.75
|
86
|
Monitoring the frequency and function of regulatory T cells and summary of the approaches currently used to inhibit regulatory T cells in cancer patients.
|
Methods Mol Biol
|
2014
|
0.75
|
87
|
Antitumor activity of delimotecan against human metastatic melanoma: pharmacokinetics and molecular determinants.
|
Int J Cancer
|
2009
|
0.75
|