Thierry Brun

Author PubWeight™ 10.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. J Clin Endocrinol Metab 2003 1.41
2 Mitochondrial dysfunction in pancreatic β cells. Trends Endocrinol Metab 2012 1.27
3 Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. J Biol Chem 2010 1.17
4 Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem 2004 1.14
5 Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction. J Biol Chem 2009 1.04
6 In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice. Diabetes 2011 0.98
7 NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion. Diabetes 2012 0.97
8 The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression. Mol Endocrinol 2004 0.94
9 Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes. BMC Mol Biol 2007 0.92
10 Role of mitochondria in beta-cell function and dysfunction. Adv Exp Med Biol 2010 0.91