Published in Arch Intern Med on June 25, 2007
Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care. World Psychiatry (2011) 5.46
Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc (2014) 2.08
Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res (2009) 1.85
Selective serotonin reuptake inhibitor treatment and risk of fractures: a meta-analysis of cohort and case-control studies. Osteoporos Int (2011) 1.72
The relationship between bisphosphonate adherence and fracture: is it the behavior or the medication? Results from the placebo arm of the fracture intervention trial. J Bone Miner Res (2011) 1.70
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology (2008) 1.56
Emerging therapeutic opportunities for skeletal restoration. Nat Rev Drug Discov (2011) 1.48
Depressive symptoms, bone loss, and fractures in postmenopausal women. J Gen Intern Med (2008) 1.21
Depression and osteoporosis: a research synthesis with meta-analysis. Horm Metab Res (2010) 1.18
Depression and osteoporosis: epidemiology and potential mediating pathways. Osteoporos Int (2007) 1.18
Update on medications with adverse skeletal effects. Mayo Clin Proc (2011) 1.16
Depression as a risk factor for osteoporosis. Trends Endocrinol Metab (2009) 1.13
Type 2 diabetes and bone fractures. Curr Opin Endocrinol Diabetes Obes (2012) 1.12
A cross-sectional evaluation of the effect of risperidone and selective serotonin reuptake inhibitors on bone mineral density in boys. J Clin Psychiatry (2010) 1.11
Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res (2010) 1.09
Depression and low bone mineral density: a meta-analysis of epidemiologic studies. Osteoporos Int (2009) 1.08
Use of anti-depressants and the risk of fracture of the hip or femur. Osteoporos Int (2009) 1.08
Depression, fracture risk, and bone loss: a meta-analysis of cohort studies. Osteoporos Int (2010) 1.08
Effects of selective serotonin reuptake inhibitors on bone health in adults: time for recommendations about screening, prevention and management? Bone (2009) 1.04
A lifespan view of anxiety disorders. Dialogues Clin Neurosci (2011) 1.04
Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study. Osteoporos Int (2009) 1.02
Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels. Bone (2010) 1.00
Skeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: evidence from in vitro and animal-based studies. J Musculoskelet Neuronal Interact (2008) 0.99
Serotonin-norepinephrine reuptake inhibitor therapy in late-life depression is associated with increased marker of bone resorption. Osteoporos Int (2013) 0.99
Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations. Perm J (2015) 0.98
Update in serotonin and bone. J Clin Endocrinol Metab (2010) 0.97
Management of psychiatric and neurological comorbidities in epilepsy. Nat Rev Neurol (2016) 0.93
Minireview: A skeleton in serotonin's closet? Endocrinology (2010) 0.93
Depression, antidepressants, and bone mineral density in a population-based cohort. J Gerontol A Biol Sci Med Sci (2008) 0.92
Relationship between use of antidepressants and risk of fractures: a meta-analysis. Osteoporos Int (2012) 0.92
Increased risk of osteoporosis-related fractures in patients with irritable bowel syndrome. Osteoporos Int (2012) 0.91
Psychotropic medication use in anorexia nervosa between 1997 and 2009. Int J Eat Disord (2012) 0.90
Dementia and hip fractures: development of a pathogenic framework for understanding and studying risk. Geriatr Orthop Surg Rehabil (2010) 0.87
Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults. World J Biol Psychiatry (2013) 0.87
Use of antidepressant medications and risk of fracture in older women. Calcif Tissue Int (2011) 0.85
Breaking into bone biology: serotonin's secrets. Nat Med (2009) 0.84
Depressive symptoms and rates of bone loss at the hip in older men. Osteoporos Int (2012) 0.84
Serotonin regulates osteoblast proliferation and function in vitro. Braz J Med Biol Res (2014) 0.83
Rates of bone loss among women initiating antidepressant medication use in midlife. J Clin Endocrinol Metab (2013) 0.83
Fracture rate in patients with myasthenia gravis: the general practice research database. Osteoporos Int (2012) 0.82
Multimorbidity in women with and without osteoporosis: results from a large US retrospective cohort study 2004-2009. Osteoporos Int (2014) 0.82
The associations of serum serotonin with bone traits are age- and gender-specific. PLoS One (2014) 0.82
Affective Disorders, Bone Metabolism, and Osteoporosis. Clin Rev Bone Miner Metab (2008) 0.82
SSRIs: bad to the bone? Innov Clin Neurosci (2012) 0.82
Mend the mind, but mind the bones!: balancing benefits and potential skeletal risks of serotonin reuptake inhibitors. Arch Intern Med (2007) 0.81
Excess risk of hip fractures attributable to the use of antidepressants in five European countries and the USA. Osteoporos Int (2014) 0.80
Are selective serotonin reuptake inhibitors a secondary cause of low bone density? J Osteoporos (2012) 0.79
Fractures in users of antidepressants and anxiolytics and sedatives: effects of age and dose. Osteoporos Int (2012) 0.78
Effects of escitalopram on markers of bone turnover: a randomized clinical trial. J Clin Endocrinol Metab (2014) 0.78
Bone density and depressive disorder: a meta-analysis. Brain Behav (2016) 0.78
Risk of Hip Fracture in Older People Using Selective Serotonin Reuptake Inhibitors and Other Psychoactive Medicines Concurrently: A Matched Case-Control Study in Australia. Drugs Real World Outcomes (2017) 0.78
Effect of Fluoxetine Consumption on Orthodontic Tooth Movement in Rats. J Dent (Tehran) (2015) 0.77
Does medication adherence itself confer fracture protection? An investigation of the healthy adherer effect in observational data. Arthritis Care Res (Hoboken) (2012) 0.77
Effects of depression and antidepressant medications on hip fracture: A population-based cohort study in Taiwan. Medicine (Baltimore) (2016) 0.77
Bone density characteristics and major depressive disorder in adolescents. Psychosom Med (2013) 0.77
Selective serotonin reuptake inhibitors and the risk of osseointegrated implant failure: a cohort study. J Dent Res (2014) 0.77
Treatment of osteoporosis: current state of the art. Wien Med Wochenschr (2014) 0.77
Bone health in patients with multiple sclerosis. J Osteoporos (2011) 0.76
Evaluation of the effect of selective serotonin reuptake inhibitors on bone mineral density: an observational cross-sectional study. Osteoporos Int (2014) 0.76
Systemic effects of fluoxetine on the amount of tooth movement, root resorption, and alveolar bone remodeling during orthodontic force application in rat. Dent Res J (Isfahan) (2015) 0.76
The association between major depressive disorder, use of antidepressants and bone mineral density (BMD) in men. J Musculoskelet Neuronal Interact (2015) 0.75
Selective serotonin reuptake inhibitors and osteoporosis: pathomechanism and clinical relevance remain to be established. Arch Intern Med (2008) 0.75
The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line. BMC Vet Res (2013) 0.75
Chronic administration of anticonvulsants but not antidepressants impairs bone strength: clinical implications. Transl Psychiatry (2015) 0.75
Concerns about bone safety of tricyclic antidepressant therapy. Arch Intern Med (2008) 0.75
Adverse bone effects of medications used to treat non-skeletal disorders. Osteoporos Int (2017) 0.75
Serotonergic Mechanisms Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance. Handb Exp Pharmacol (2016) 0.75
Bone Turnover with Venlafaxine Treatment in Older Adults with Depression. J Am Geriatr Soc (2017) 0.75
Patterns of selective serotonin reuptake inhibitor use and risk of falls and fractures in community-dwelling elderly people: the Three-City cohort. Osteoporos Int (2016) 0.75
Serum serotonin levels and bone in rheumatoid arthritis patients. Rheumatol Int (2017) 0.75
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA (2006) 12.47
The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurol (2011) 8.15
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med (2003) 7.25
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Functional status of elderly adults before and after initiation of dialysis. N Engl J Med (2009) 6.45
Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA (2005) 6.20
Bone-density testing interval and transition to osteoporosis in older women. N Engl J Med (2012) 5.81
Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA (2009) 5.75
Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ (2005) 5.34
Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA (2003) 5.23
Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med (2008) 5.14
The NIH Cognitive and Emotional Health Project. Report of the Critical Evaluation Study Committee. Alzheimers Dement (2006) 5.05
Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA (2011) 4.83
Hearing loss and cognitive decline in older adults. JAMA Intern Med (2013) 4.25
One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis. N Engl J Med (2005) 4.03
Kidney function and cognitive impairment in US adults: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis (2008) 3.87
Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study. Arch Gen Psychiatry (2006) 3.61
Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2007) 3.61
A cognitive training program based on principles of brain plasticity: results from the Improvement in Memory with Plasticity-based Adaptive Cognitive Training (IMPACT) study. J Am Geriatr Soc (2009) 3.58
Limited literacy and mortality in the elderly: the health, aging, and body composition study. J Gen Intern Med (2006) 3.51
Bone mineral density and the risk of incident nonspinal fractures in black and white women. JAMA (2005) 3.30
Renal function and risk of hip and vertebral fractures in older women. Arch Intern Med (2007) 3.27
Position statement of the American Association for Geriatric Psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry (2006) 3.22
The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death. Arch Intern Med (2011) 3.17
Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci (2007) 3.16
Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc (2007) 3.15
Long-term risk of incident vertebral fractures. JAMA (2007) 3.15
Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol (2005) 3.14
Patient and caregiver characteristics associated with depression in caregivers of patients with dementia. J Gen Intern Med (2003) 3.13
A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults. J Am Geriatr Soc (2003) 3.09
Central nervous system-active medications and risk for falls in older women. J Am Geriatr Soc (2002) 3.03
The association between physical function and lifestyle activity and exercise in the health, aging and body composition study. J Am Geriatr Soc (2004) 2.93
Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study. Arch Intern Med (2009) 2.82
Additive effects of cognitive function and depressive symptoms on mortality in elderly community-living adults. J Gerontol A Biol Sci Med Sci (2003) 2.82
Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry (2003) 2.77
Poor sleep is associated with impaired cognitive function in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci (2006) 2.73
Older women with diabetes have a higher risk of falls: a prospective study. Diabetes Care (2002) 2.72
Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. JAMA (2011) 2.70
Contribution of Alzheimer disease to mortality in the United States. Neurology (2014) 2.67
Cost-effectiveness of bone densitometry followed by treatment of osteoporosis in older men. JAMA (2007) 2.62
Training the next generation of research mentors: the University of California, San Francisco, Clinical & Translational Science Institute Mentor Development Program. Clin Transl Sci (2009) 2.60
Cognitive impairment in chronic kidney disease. J Am Geriatr Soc (2004) 2.50
Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women. Ann Neurol (2011) 2.46
High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry (2010) 2.43
Relationship of changes in physical activity and mortality among older women. JAMA (2003) 2.42
Association between physical and cognitive function in healthy elderly: the health, aging and body composition study. Neuroepidemiology (2005) 2.39
Hip fracture in women without osteoporosis. J Clin Endocrinol Metab (2005) 2.35
Depression and risk of developing dementia. Nat Rev Neurol (2011) 2.31
Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial. J Bone Miner Res (2010) 2.29
Adverse oral health and cognitive decline: the health, aging and body composition study. J Am Geriatr Soc (2013) 2.27
Reduced renal function and sleep-disordered breathing in community-dwelling elderly men. Sleep Med (2008) 2.26
Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr Alzheimer Res (2007) 2.19
Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures. J Bone Miner Res (2008) 2.18
Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men. Arch Intern Med (2007) 2.17
Diabetes and incidence of functional disability in older women. Diabetes Care (2002) 2.16
Promising strategies for the prevention of dementia. Arch Neurol (2009) 2.14
Evaluating the value of repeat bone mineral density measurement and prediction of fractures in older women: the study of osteoporotic fractures. Arch Intern Med (2007) 2.10
ACNP White Paper: update on use of antipsychotic drugs in elderly persons with dementia. Neuropsychopharmacology (2007) 2.09
Decreased slow wave sleep increases risk of developing hypertension in elderly men. Hypertension (2011) 2.09
Activity energy expenditure and incident cognitive impairment in older adults. Arch Intern Med (2011) 2.07
Limited literacy in older people and disparities in health and healthcare access. J Am Geriatr Soc (2006) 2.06
The Mental Activity and eXercise (MAX) trial: a randomized controlled trial to enhance cognitive function in older adults. JAMA Intern Med (2013) 2.05
Association of BMD and FRAX score with risk of fracture in older adults with type 2 diabetes. JAMA (2011) 2.04
Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology (2004) 2.02
Effect of postmenopausal hormone therapy on cognitive function: the Heart and Estrogen/progestin Replacement Study. Am J Med (2002) 2.02
Executive function, more than global cognition, predicts functional decline and mortality in elderly women. J Gerontol A Biol Sci Med Sci (2007) 1.97
Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults. J Am Geriatr Soc (2012) 1.96
Change in cognitive function by glucose tolerance status in older adults: a 4-year prospective study of the Rancho Bernardo study cohort. Arch Intern Med (2004) 1.95
Circulating 25-hydroxyvitamin D levels and frailty status in older women. J Clin Endocrinol Metab (2010) 1.93
Predictors of non-spine fracture in elderly men: the MrOS study. J Bone Miner Res (2007) 1.93
Chronic kidney disease and cognitive impairment in menopausal women. Am J Kidney Dis (2005) 1.91
BMD and risk of hip and nonvertebral fractures in older men: a prospective study and comparison with older women. J Bone Miner Res (2006) 1.91
Alendronate treatment in women with normal to severely impaired renal function: an analysis of the fracture intervention trial. J Bone Miner Res (2007) 1.88
Depressive symptoms in middle age and the development of later-life functional limitations: the long-term effect of depressive symptoms. J Am Geriatr Soc (2010) 1.88
Vision impairment and combined vision and hearing impairment predict cognitive and functional decline in older women. J Am Geriatr Soc (2004) 1.88
Long-term prediction of incident hip fracture risk in elderly white women: study of osteoporotic fractures. J Am Geriatr Soc (2004) 1.84
Poor sleep is associated with poorer physical performance and greater functional limitations in older women. Sleep (2007) 1.82
Factors associated with the lumbar spine and proximal femur bone mineral density in older men. Osteoporos Int (2005) 1.82
Cost-effectiveness of alendronate therapy for osteopenic postmenopausal women. Ann Intern Med (2005) 1.81
A meta-analysis of cortisol response to challenge in human aging: importance of gender. Psychoneuroendocrinology (2005) 1.79
Breast cancer incidence in the randomized PEARL trial of lasofoxifene in postmenopausal osteoporotic women. J Natl Cancer Inst (2010) 1.79
Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PLoS One (2011) 1.78
Screening for osteoporosis: an update for the U.S. Preventive Services Task Force. Ann Intern Med (2010) 1.76
What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res (2005) 1.76
Physical activity over the life course and its association with cognitive performance and impairment in old age. J Am Geriatr Soc (2010) 1.76
Cognitive impairment, depressive symptoms, and functional decline in older people. J Am Geriatr Soc (2002) 1.76
Prevalence and correlates of periodic limb movements in older women. J Clin Sleep Med (2006) 1.76
Comparison of sleep parameters from actigraphy and polysomnography in older women: the SOF study. Sleep (2008) 1.75