Published in Biofactors on January 01, 2007
G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov (2011) 3.31
Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. Biochem Pharmacol (2010) 1.52
EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway. Oncogene (2011) 1.42
Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy. Clin Dev Immunol (2011) 1.41
Pre-folding IkappaBalpha alters control of NF-kappaB signaling. J Mol Biol (2008) 1.35
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B. Blood (2012) 1.29
Overexpression of candidate tumor suppressor ECRG4 inhibits glioma proliferation and invasion. J Exp Clin Cancer Res (2010) 1.28
Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanisms. Int J Environ Res Public Health (2013) 1.26
Mycoplasma infection suppresses p53, activates NF-kappaB and cooperates with oncogenic Ras in rodent fibroblast transformation. Oncogene (2008) 1.20
Molecular targets for treatment of inflammatory breast cancer. Nat Rev Clin Oncol (2009) 1.19
The ubiquitin-like protein FAT10 mediates NF-kappaB activation. J Am Soc Nephrol (2009) 1.17
The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface. Protein Sci (2008) 1.15
Real-time monitoring of nuclear factor kappaB activity in cultured cells and in animal models. Mol Imaging (2009) 1.13
Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin. J Biol Chem (2010) 1.10
NF-κB gene signature predicts prostate cancer progression. Cancer Res (2014) 1.09
Evidence that cisplatin-induced auditory damage is attenuated by downregulation of pro-inflammatory cytokines via Nrf2/HO-1. J Assoc Res Otolaryngol (2008) 1.06
Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. Int J Cancer (2009) 1.03
The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy. Sci Rep (2013) 1.03
Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification. Endocr Metab Immune Disord Drug Targets (2009) 1.01
Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades. Curr Cancer Drug Targets (2009) 1.00
Activation of NF-kappa B signaling promotes growth of prostate cancer cells in bone. PLoS One (2013) 0.99
New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer. Nutr Cancer (2011) 0.98
Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA. Proc Natl Acad Sci U S A (2013) 0.98
CAPC negatively regulates NF-κB activation and suppresses tumor growth and metastasis. Oncogene (2011) 0.98
Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians. Cancer Epidemiol Biomarkers Prev (2012) 0.94
RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells. Ann N Y Acad Sci (2010) 0.93
Genomics of the NF-κB signaling pathway: hypothesized role in ovarian cancer. Cancer Causes Control (2011) 0.91
Cylindroma transforming into basal cell carcinoma in a patient with Brooke-Spiegler syndrome. J Dermatol Case Rep (2007) 0.90
The pharmacological NF-κB inhibitor BAY11-7082 induces cell apoptosis and inhibits the migration of human uveal melanoma cells. Int J Mol Sci (2012) 0.89
Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection. J Transl Med (2013) 0.88
Different patterns of NF-κB and Notch1 signaling contribute to tumor-induced lymphangiogenesis of esophageal squamous cell carcinoma. J Exp Clin Cancer Res (2011) 0.87
Anti-angiogenic effects of pterogynidine alkaloid isolated from Alchornea glandulosa. BMC Complement Altern Med (2009) 0.85
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma. Oncotarget (2015) 0.84
Inflammation in prostate cancer progression and therapeutic targeting. Transl Androl Urol (2015) 0.83
Transcription Factors in the Cellular Response to Charged Particle Exposure. Front Oncol (2016) 0.83
Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells. Oncotarget (2015) 0.82
To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator. Transl Med UniSa (2012) 0.82
PEST Control of Molecular Stripping of NFκB from DNA Transcription Sites. J Phys Chem B (2016) 0.82
Guggulsterone enhances antitumor activity of gemcitabine in gallbladder cancer cells through suppression of NF-κB. J Cancer Res Clin Oncol (2012) 0.82
Eugenol triggers apoptosis in breast cancer cells through E2F1/survivin down-regulation. BMC Cancer (2013) 0.82
Targeting lentiviral vectors for cancer immunotherapy. Curr Cancer Ther Rev (2011) 0.80
Studies in experimental autoimmune encephalomyelitis do not support developmental bisphenol a exposure as an environmental factor in increasing multiple sclerosis risk. Toxicol Sci (2013) 0.80
Identifying novel glioma associated pathways based on systems biology level meta-analysis. BMC Syst Biol (2013) 0.80
Prognostic value of the expression of phosphatase and tensin homolog and CD44 in elderly patients with refractory acute myeloid leukemia. Oncol Lett (2015) 0.80
Toad glandular secretions and skin extractions as anti-inflammatory and anticancer agents. Evid Based Complement Alternat Med (2014) 0.79
Isoform-specific modulation of pressure-stimulated cancer cell proliferation and adhesion by α-actinin. Am J Surg (2011) 0.79
Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: the roles of NF-kappaB and crosstalk between the extrinsic and intrinsic apoptotic pathways. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.79
Fibromodulin suppresses nuclear factor-kappaB activity by inducing the delayed degradation of IKBA via a JNK-dependent pathway coupled to fibroblast apoptosis. J Biol Chem (2010) 0.79
Icotinib inhibits the invasion of Tca8113 cells via downregulation of nuclear factor κB-mediated matrix metalloproteinase expression. Oncol Lett (2014) 0.78
Prognostic value of c-FLIPL/s, HIF-1α, and NF-κβ in stage II and III rectal cancer. Virchows Arch (2014) 0.77
Hit identification of IKKβ natural product inhibitor. BMC Pharmacol Toxicol (2013) 0.76
Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β. Mol Oncol (2014) 0.76
Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-κB inhibition. J Cell Mol Med (2015) 0.76
Cylindroma of the scalp. J Res Med Sci (2015) 0.75
UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer. Int J Mol Sci (2016) 0.75
Anticancer activities of alkaloids extracted from the Ba lotus seed in human nasopharyngeal carcinoma CNE-1 cells. Exp Ther Med (2016) 0.75
Enhancement of hyperthermia-induced apoptosis by 5Z-7-oxozeaenol, a TAK1 inhibitor, in A549 cells. Cell Stress Chaperones (2016) 0.75
Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathway. BMC Cancer (2016) 0.75
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents. Bioorg Med Chem (2015) 0.75
Cocculus hirsutus: Molecular Docking to Identify Suitable Targets for Hepatocellular Carcinoma by In silico Technique. Pharmacogn Mag (2016) 0.75
Glaucine inhibits breast cancer cell migration and invasion by inhibiting MMP-9 gene expression through the suppression of NF-κB activation. Mol Cell Biochem (2015) 0.75
Acetylshikonin Inhibits Human Pancreatic PANC-1 Cancer Cell Proliferation by Suppressing the NF-κB Activity. Biomol Ther (Seoul) (2015) 0.75
Anticancer activity of Nelumbo nucifera stamen extract in human colon cancer HCT-116 cells in vitro. Oncol Lett (2016) 0.75
Adrenomedullin inhibits osteoclast differentiation through the suppression of receptor activator of nuclear factor-κB ligand-induced nuclear factor-κB activation in glucocorticoid-induced osteoporosis. Exp Ther Med (2017) 0.75
In vivo toxicity study of N-1-sulfonylcytosine derivatives and their mechanisms of action in cervical carcinoma cell line. Invest New Drugs (2011) 0.75
Potential malignant transformation in the gastric mucosa of immunodeficient mice with persistent Mycoplasma penetrans infection. PLoS One (2017) 0.75
Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line. Oncol Lett (2017) 0.75
Feasibility of ovarian preservation in patients with early stage endometrial carcinoma. Gynecol Oncol (2006) 1.57
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem (2010) 1.46
Prognostic value of preoperative metabolic tumor volume and total lesion glycolysis in patients with epithelial ovarian cancer. Ann Surg Oncol (2011) 1.28
Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation. Carcinogenesis (2003) 1.25
Akt involvement in paclitaxel chemoresistance of human ovarian cancer cells. Ann N Y Acad Sci (2007) 1.23
Use of preoperative serum CA-125 levels for prediction of lymph node metastasis and prognosis in endometrial cancer. Acta Obstet Gynecol Scand (2006) 1.16
Clinical impact of integrated PET/CT on the management of suspected cervical cancer recurrence. Gynecol Oncol (2006) 1.13
Role of [18F]FDG PET/CT in the assessment of suspected recurrent ovarian cancer: correlation with clinical or histological findings. Eur J Nucl Med Mol Imaging (2006) 1.09
Gamma-knife radiosurgery as an optimal treatment modality for brain metastases from epithelial ovarian cancer. Gynecol Oncol (2008) 1.07
Prognostic value of metabolic tumor volume measured by FDG-PET/CT in patients with cervical cancer. Gynecol Oncol (2010) 1.06
A hospital-based case-control study of identifying ovarian cancer using symptom index. J Gynecol Oncol (2009) 1.06
Expression of vascular endothelial growth factor and hypoxia inducible factor-1alpha in cervical neoplasia. Ann N Y Acad Sci (2009) 1.05
Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer. Gynecol Oncol (2011) 1.04
XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer. Gynecol Oncol (2006) 1.02
Rapid and high-throughput analysis of N-glycans from ovarian cancer serum using a 96-well plate platform. Anal Biochem (2009) 1.00
The clinical impact of [(18)F]FDG PET/CT for the management of recurrent endometrial cancer: correlation with clinical and histological findings. Eur J Nucl Med Mol Imaging (2008) 0.99
Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells. Carcinogenesis (2012) 0.99
Involvement of NF-kappaB and AP-1 in COX-2 upregulation by human papillomavirus 16 E5 oncoprotein. Carcinogenesis (2009) 0.98
Serum CA-125 level after 6 cycles of primary adjuvant chemotherapy is a useful prognostic factor for complete responders' survival in patients with advanced epithelial ovarian cancer. Onkologie (2008) 0.97
Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kappaB as a possible target. J Cancer Res Clin Oncol (2004) 0.97
Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model. J Natl Cancer Inst (2013) 0.96
XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response to platinum-based neoadjuvant chemotherapy in cervical cancer. Gynecol Oncol (2008) 0.96
Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells. Carcinogenesis (2009) 0.95
Human papillomavirus E5 protein induces expression of the EP4 subtype of prostaglandin E2 receptor in cyclic AMP response element-dependent pathways in cervical cancer cells. Carcinogenesis (2008) 0.95
Derepression of CLDN3 and CLDN4 during ovarian tumorigenesis is associated with loss of repressive histone modifications. Carcinogenesis (2010) 0.95
CA19-9 elevation in ovarian mature cystic teratoma: discrimination from ovarian cancer - CA19-9 level in teratoma. Med Sci Monit (2013) 0.95
Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model. J Natl Cancer Inst (2012) 0.94
Association of promoter hypermethylation of the RASSF1A gene with prognostic parameters in endometrial cancer. Oncol Res (2006) 0.94
Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells. PLoS One (2012) 0.93
Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin. J Biol Chem (2013) 0.93
Vaginal pH-balanced gel for the control of atrophic vaginitis among breast cancer survivors: a randomized controlled trial. Obstet Gynecol (2011) 0.93
Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death. PLoS One (2012) 0.92
Hereditary nonpolyposis colorectal cancer in endometrial cancer patients. Int J Cancer (2008) 0.92
Expression of cyclooxygenase-1 and -2 associated with expression of VEGF in primary cervical cancer and at metastatic lymph nodes. Gynecol Oncol (2003) 0.92
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis (2007) 0.92
Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment. Biochem Pharmacol (2010) 0.92
Characterization of surgically transposed ovaries in integrated PET/CT scan in patients with cervical cancer. Acta Obstet Gynecol Scand (2007) 0.92
Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin. Carcinogenesis (2004) 0.91
Preoperative [F]FDG PET/CT predicts recurrence in patients with epithelial ovarian cancer. J Gynecol Oncol (2012) 0.90
Underuse of ovarian transposition in reproductive-aged cancer patients treated by primary or adjuvant pelvic irradiation. J Obstet Gynaecol Res (2011) 0.90
Predictive value of individualized tumor response testing by ATP-based chemotherapy response assay in ovarian cancer. Cancer Invest (2008) 0.89
Human papillomavirus vaccine: widening the scope for cancer prevention. Mol Carcinog (2011) 0.89
Value of pelvic examination and imaging modality for the evaluation of tumor size in cervical cancer. J Gynecol Oncol (2008) 0.89
Presence of HPV type 6 in dysplasia and carcinoma arising from recurrent respiratory papillomatosis. Head Neck (2009) 0.88
Uterine corpus involvement as well as histologic type is an independent predictor of ovarian metastasis in uterine cervical cancer. J Gynecol Oncol (2008) 0.88
Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells. Ann N Y Acad Sci (2009) 0.87
Treatment of stage IB2, IIA bulky cervical cancer: a single-institution experience of neoadjuvant chemotherapy followed by radical hysterectomy and primary radical hysterectomy. Arch Gynecol Obstet (2010) 0.87
Diabetes mellitus and ovarian cancer risk: a systematic review and meta-analysis of observational studies. Int J Gynecol Cancer (2013) 0.86
VEGF polymorphisms in early cervical cancer susceptibility, angiogenesis, and survival. Gynecol Oncol (2010) 0.86
Identification of a patient group at low risk for parametrial invasion in early-stage cervical cancer. Gynecol Oncol (2010) 0.86
DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma. Hum Reprod (2005) 0.86
Good correlation of HPV DNA test between self-collected vaginal and clinician-collected cervical samples by the oligonucleotide microarray. Gynecol Oncol (2006) 0.86
Matrix metalloproteinase-1 promoter polymorphism and epithelial ovarian cancer: does ethnicity matter? J Obstet Gynaecol Res (2007) 0.85
Interleukin-12 p40 gene (IL12B) polymorphisms and the risk of cervical cancer in Korean women. Eur J Obstet Gynecol Reprod Biol (2008) 0.85
Hypoxia-inducible factor 1α polymorphisms and early-stage cervical cancer. Int J Gynecol Cancer (2011) 0.85
Role of integrated PET-CT in pelvic lymph node staging of cervical cancer before radical hysterectomy. Gynecol Obstet Invest (2008) 0.85
Accuracy of MR imaging for the prediction of myometrial invasion of endometrial carcinoma. Gynecol Oncol (2006) 0.85
Prognostic role of cyclooxygenase-2 in epithelial ovarian cancer: a meta-analysis of observational studies. Gynecol Oncol (2013) 0.85
Preoperative [18F]FDG PET/CT maximum standardized uptake value predicts recurrence of uterine cervical cancer. Eur J Nucl Med Mol Imaging (2010) 0.84
Expression of mTOR protein and its clinical significance in endometrial cancer. Med Sci Monit (2009) 0.84
Prognostic significance of neutropenia during adjuvant concurrent chemoradiotherapy in early cervical cancer. J Gynecol Oncol (2009) 0.84
Postoperative nomogram predicting risk of recurrence after radical hysterectomy for early-stage cervical cancer. Int J Gynecol Cancer (2010) 0.84
20 year experience of postoperative radiotherapy in IB-IIA cervical cancer patients with intermediate risk factors: impact of treatment period and concurrent chemotherapy. Gynecol Oncol (2011) 0.83
Cyclooxygenase-2 and p53 expressions in endometrial cancer. Cancer Epidemiol Biomarkers Prev (2004) 0.83
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis (2006) 0.83
Loop electrosurgical excision procedure findings for identification of patients with early-stage cervical cancer suitable for less radical surgery. Int J Gynecol Cancer (2012) 0.82
Quantitative detection of serum survivin and its relationship with prognostic factors in ovarian cancer. Gynecol Obstet Invest (2010) 0.82
A case of clear cell carcinoma arising from the endometriosis of the paraovarian cyst. J Gynecol Oncol (2009) 0.82
Necessity of education for oral contraceptive use in Korea: results from the fourth Korean national health and nutrition examination survey 2007-2009. Gynecol Obstet Invest (2013) 0.81
The influence of adjuvant radiotherapy on patterns of failure and survivals in uterine carcinosarcoma. Radiat Oncol J (2011) 0.81
Predictive role of post-treatment [18F]FDG PET/CT in patients with uterine cervical cancer. Eur J Radiol (2012) 0.81
Cyclooxygenase-2 is an independent predictor of poor prognosis in uterine leiomyosarcomas. Int J Gynecol Cancer (2011) 0.81
The role of omentectomy and random peritoneal biopsies as part of comprehensive surgical staging in apparent early-stage epithelial ovarian cancer. Ann Surg Oncol (2014) 0.80
Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer? Jpn J Clin Oncol (2007) 0.80
Disease confined within the ovary and smaller amount of ascites are good prognostic factors for survival of patients with squamous cell carcinoma arising from mature cystic teratoma of the ovary: a case series in Korea and review of the published reports. J Obstet Gynaecol Res (2009) 0.80
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia. Ann N Y Acad Sci (2009) 0.80
Diallyl trisulfide-induced G2/M phase cell cycle arrest in DU145 cells is associated with delayed nuclear translocation of cyclin-dependent kinase 1. Pharm Res (2010) 0.80
Prognosis of adenosquamous carcinoma compared with adenocarcinoma in uterine cervical cancer: a systematic review and meta-analysis of observational studies. Int J Gynecol Cancer (2014) 0.80
Feasibility of less radical surgery for superficially invasive carcinoma of the cervix. Gynecol Oncol (2010) 0.80
Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer. Am J Obstet Gynecol (2010) 0.79
P53 codon 72 and p21 codon 31 polymorphisms and susceptibility to cervical adenocarcinoma in Korean women. Oncol Res (2010) 0.79
Cyclin D1 G870A polymorphism and squamous cell carcinoma of the uterine cervix in Korean women. Cancer Lett (2005) 0.78
Apoptotic effect of celecoxib dependent upon p53 status in human ovarian cancer cells. Ann N Y Acad Sci (2007) 0.78
Gonadotropin-releasing hormone receptor expression in endometrial cancer. Int J Gynecol Pathol (2009) 0.78