Published in Toxicol Appl Pharmacol on June 07, 2007
Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal (2009) 2.33
Retracted Non-thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species. Ann Biomed Eng (2010) 1.54
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer. Cancer Res (2008) 1.39
Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiols. J Cell Biochem (2010) 0.99
5-hydroxy-2-methyl-1,4-naphthoquinone, a vitamin K3 analogue, suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase, SHP-1: potential role in chemosensitization. Mol Cancer Res (2010) 0.93
The natural anticancer agent plumbagin induces potent cytotoxicity in MCF-7 human breast cancer cells by inhibiting a PI-5 kinase for ROS generation. PLoS One (2012) 0.92
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), isolated from Plumbago zeylanica, inhibits ultraviolet radiation-induced development of squamous cell carcinomas. Carcinogenesis (2011) 0.90
Venus Flytrap (Dionaea muscipula Solander ex Ellis) Contains Powerful Compounds that Prevent and Cure Cancer. Front Oncol (2013) 0.86
Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression. Leuk Res (2011) 0.84
Plumbagin promotes the generation of astrocytes from rat spinal cord neural progenitors via activation of the transcription factor Stat3. J Neurochem (2010) 0.83
JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. Cell Death Dis (2014) 0.81
Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells. PLoS One (2016) 0.79
Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB). Sci Rep (2016) 0.78
Effects of a Nonthermal Atmospheric Pressure Plasma Jet on Human Gingival Fibroblasts for Biomedical Application. Biomed Res Int (2016) 0.75
Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation. Sci Rep (2017) 0.75
Dickeya solani sp. nov., a pectinolytic plant-pathogenic bacterium isolated from potato (Solanum tuberosum). Int J Syst Evol Microbiol (2013) 1.80
LC/MS profiling of flavonoid glycoconjugates isolated from hairy roots, suspension root cell cultures and seedling roots of Medicago truncatula. Metabolomics (2011) 1.10
Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer. J Transl Med (2009) 1.04
Selective disruption of wheat secondary metabolism by herbicide safeners. Phytochemistry (2006) 1.02
Genotyping of bacteria belonging to the former Erwinia genus by PCR-RFLP analysis of a recA gene fragment. Microbiology (2002) 0.97
Transcription factor AtDOF4;2 affects phenylpropanoid metabolism in Arabidopsis thaliana. New Phytol (2007) 0.96
Complete genome sequence of a broad-host-range lytic Dickeya spp. bacteriophage ϕD5. Arch Virol (2014) 0.92
Induction of apoptosis in HL-60 cells through the ROS-mediated mitochondrial pathway by ramentaceone from Drosera aliciae. J Nat Prod (2012) 0.90
Caffeine, pentoxifylline and theophylline form stacking complexes with IQ-type heterocyclic aromatic amines. Bioorg Chem (2010) 0.89
Plumbagin induces apoptosis in Her2-overexpressing breast cancer cells through the mitochondrial-mediated pathway. J Nat Prod (2012) 0.89
Differentiation of isomeric malonylated flavonoid glyconjugates in plant extracts with UPLC-ESI/MS/MS. Phytochem Anal (2008) 0.89
The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine. Biochem Pharmacol (2002) 0.88
Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: association with tumor progression. Int J Oncol (2011) 0.87
In vitro and in vivo analyses of the biological activity of RGD peptides towards Ab Bomirski melanoma. Cell Mol Biol Lett (2003) 0.86
Radiation-related changes in serum proteome profiles detected by mass spectrometry in blood of patients treated with radiotherapy due to larynx cancer. J Radiat Res (2011) 0.86
Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer. J Transl Med (2010) 0.85
Inactivation of AHLs by Ochrobactrum sp. A44 depends on the activity of a novel class of AHL acylase. Environ Microbiol Rep (2011) 0.84
Regulators involved in Dickeya solani virulence, genetic conservation, and functional variability. Mol Plant Microbe Interact (2014) 0.84
Changes in the profile of flavonoid accumulation in Medicago truncatula leaves during infection with fungal pathogen Phoma medicaginis. Plant Physiol Biochem (2009) 0.84
Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors. Biotechnol Prog (2007) 0.80
Effect of l-phenylalanine on PAL activity and production of naphthoquinone pigments in suspension cultures of Arnebia euchroma (Royle) Johnst. In Vitro Cell Dev Biol Plant (2012) 0.80
Mutagenicity of quaternary ammonium salts containing carbohydrate moieties. J Hazard Mater (2011) 0.80
Increased mitochondrial superoxide dismutase expression and lowered production of reactive oxygen species during rotavirus infection. Virology (2010) 0.80
Formation of stacking complexes between caffeine (1,2,3-trimethylxanthine) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine may attenuate biological effects of this neurotoxin. Bioorg Chem (2005) 0.80
Antitumor activity of antimicrobial peptides against U937 histiocytic cell line. Acta Biochim Pol (2011) 0.80
Fragmentation pathways of acylated flavonoid diglucuronides from leaves of Medicago truncatula. Phytochem Anal (2010) 0.80
Structural analysis and profiling of phenolic secondary metabolites of Mexican lupine species using LC-MS techniques. Phytochemistry (2013) 0.80
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry monitoring of anthocyanins in extracts from Arabidopsis thaliana leaves. Rapid Commun Mass Spectrom (2008) 0.79
Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients. Int J Radiat Biol (2011) 0.79
Activation of phenylpropanoid pathway in legume plants exposed to heavy metals. Part II. Profiling of isoflavonoids and their glycoconjugates induced in roots of lupine (Lupinus luteus) seedlings treated with cadmium and lead. Acta Biochim Pol (2011) 0.79
Structural characterization of flavonoid glycosides from leaves of wheat (Triticum aestivum L.) using LC/MS/MS profiling of the target compounds. J Mass Spectrom (2013) 0.79
The mobilization of defence mechanisms in the early stages of pea seed germination against Ascochyta pisi. Protoplasma (2012) 0.79
Sucrose-induced lupine defense against Fusarium oxysporum. Sucrose-stimulated accumulation of isoflavonoids as a defense response of lupine to Fusarium oxysporum. Plant Physiol Biochem (2005) 0.79
Impaired mutagenic activities of MPDP(+) (1-methyl-4-phenyl-2,3-dihydropyridinium) and MPP(+) (1-methyl-4-phenylpyridinium) due to their interactions with methylxanthines. Bioorg Med Chem (2007) 0.78
Molecular cloning and sequencing of partial cDNA of tumor necrosis factor and p75 tumor necrosis factor receptor of Syrian golden hamster (Mesocricetus auratus) with the use of universal primers. Acta Biochim Pol (2002) 0.77
Native transfer RNA catalyzes Diels-Alder reaction. Biochem Biophys Res Commun (2002) 0.77
A novel mechanism of action of the fumagillin analog, TNP-470, in the B16F10 murine melanoma cell line. Anticancer Drugs (2005) 0.76
Activities of synthetic peptides against human pathogenic bacteria. Pol J Microbiol (2004) 0.76
Modulation of acridine mutagen ICR191 intercalation to DNA by methylxanthines--analysis with mathematical models. Bioorg Med Chem (2013) 0.76
Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry. J Proteomics (2011) 0.76
Caffeine and other methylxanthines as interceptors of food-borne aromatic mutagens: inhibition of Trp-P-1 and Trp-P-2 mutagenic activity. Chem Res Toxicol (2013) 0.76
Changes of phenolic secondary metabolite profiles in the reaction of narrow leaf lupin (Lupinus angustifolius) plants to infections with Colletotrichum lupini fungus or treatment with its toxin. Metabolomics (2012) 0.76
Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid chromatography/mass spectrometry. Anal Biochem (2010) 0.75
Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis. Amino Acids (2014) 0.75
Identification of QTLs affecting scopolin and scopoletin biosynthesis in Arabidopsis thaliana. BMC Plant Biol (2014) 0.75
Anti-tumor action of tumor necrosis factor against Bomirski Ab melanoma in hamsters. Arch Immunol Ther Exp (Warsz) (2007) 0.75
Electrospray mass spectrometric decomposition of some glucuronic acid-containing flavonoid diglycosides. Phytochem Anal (2003) 0.75
[Mechanism of transcription factor NF kappa B activation by tumor necrosis factor (TNF)]. Postepy Biochem (2002) 0.75
The atypical pattern of cell death in B16F10 melanoma cells treated with TNP-470. Cell Mol Biol Lett (2006) 0.75
Differentiation between isomeric acacetin-6-C-(6"-O-malonyl)glucoside and acacetin-8-C-(6"-O-malonyl)glucoside by using low-energy CID mass spectra. J Mass Spectrom (2002) 0.75
Influence of plant secondary metabolites on in vitro oxidation of methyl ferulate with cell wall peroxidases from lupine apoplast. J Plant Physiol (2007) 0.75
Differentiation of interglycosidic linkages in permethylated flavonoid glycosides from linked-scan mass spectra (B/E). J Agric Food Chem (2002) 0.75
Antibacterial and antioxidant activity of the secondary metabolites from in vitro cultures of the Alice sundew (Drosera aliciae). Biotechnol Appl Biochem (2009) 0.75
Rapid detection of mutagens accumulated in plant tissues using a novel Vibrio harveyi mutagenicity assay. Ecotoxicol Environ Saf (2007) 0.75
Profiling isoflavone conjugates in root extracts of lupine species with LC/ESI/MSn systems. J Mass Spectrom (2005) 0.75
Application of mass spectrometric techniques for structural analysis of apigenin 8-C-(6"-O-glucopyranosyl) glucopyranoside--a novel flavonoid C-diglycoside. Rapid Commun Mass Spectrom (2003) 0.75
[Heterocyclic aromatic amines, food-derived mutagens: metabolism and relevance to cancer susceptibility]. Postepy Biochem (2010) 0.75
[Serum anti-P53 antibodies (AB-anti-P53) in patients with advanced non-small cell lung cancer (NSCLC)]. Pneumonol Alergol Pol (2002) 0.75