Published in J Proteome Res on July 11, 2007
A straightforward and highly efficient precipitation/on-pellet digestion procedure coupled with a long gradient nano-LC separation and Orbitrap mass spectrometry for label-free expression profiling of the swine heart mitochondrial proteome. J Proteome Res (2009) 1.46
Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics. J Bacteriol (2010) 1.05
Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes. Basal Ganglia (2012) 1.02
Quantitative measurement of phosphoproteome response to osmotic stress in arabidopsis based on Library-Assisted eXtracted Ion Chromatogram (LAXIC). Mol Cell Proteomics (2013) 0.95
Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1. J Huntingtons Dis (2012) 0.91
Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease. Mol Cell Proteomics (2008) 0.88
Stable isotope labeling and label-free proteomics of Drosophila parkin null mutants. J Proteome Res (2009) 0.83
Proteome response to the panneural expression of human wild-type alpha-synuclein: a Drosophila model of Parkinson's disease. J Proteome Res (2008) 0.82
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. J Proteome Res (2012) 0.80
Proteostasis in striatal cells and selective neurodegeneration in Huntington's disease. Front Cell Neurosci (2014) 0.78
Structural separations by ion mobility-MS for glycomics and glycoproteomics. Methods Mol Biol (2013) 0.78
Anatomo-proteomic characterization of human basal ganglia: focus on striatum and globus pallidus. Mol Brain (2014) 0.75
The heat shock response in neurons and astroglia and its role in neurodegenerative diseases. Mol Neurodegener (2017) 0.75
Mass spectrometry-based proteomics. Nature (2003) 28.94
Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol (2001) 28.01
The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics (2002) 16.08
Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry. Proc Natl Acad Sci U S A (2004) 13.14
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell (1996) 12.59
Impairment of the ubiquitin-proteasome system by protein aggregation. Science (2001) 11.51
Toxic proteins in neurodegenerative disease. Science (2002) 5.82
Automated approach for quantitative analysis of complex peptide mixtures from tandem mass spectra. Nat Methods (2004) 4.62
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J Neurosci (1999) 4.56
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum Mol Genet (2000) 3.07
Huntingtin aggregation and toxicity in Huntington's disease. Lancet (2003) 2.72
Inhibitors of the HSP90 molecular chaperone: current status. Adv Cancer Res (2006) 2.55
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
Toward plasma proteome profiling with ion mobility-mass spectrometry. J Proteome Res (2006) 2.18
Development and evaluation of a micro- and nanoscale proteomic sample preparation method. J Proteome Res (2005) 2.06
Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome. Anal Chem (2004) 2.00
Mapping the human plasma proteome by SCX-LC-IMS-MS. J Am Soc Mass Spectrom (2007) 1.94
Characterization of the mouse brain proteome using global proteomic analysis complemented with cysteinyl-peptide enrichment. J Proteome Res (2006) 1.93
Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics. Anal Chem (2005) 1.87
Oxidative stress in Huntington's disease. Brain Pathol (1999) 1.80
The energetics of Huntington's disease. Neurochem Res (2004) 1.79
Impaired glutamate uptake in the R6 Huntington's disease transgenic mice. Neurobiol Dis (2001) 1.71
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain (2002) 1.71
Differential analysis of membrane proteins in mouse fore- and hindbrain using a label-free approach. J Proteome Res (2006) 1.71
Development of high-sensitivity ion trap ion mobility spectrometry time-of-flight techniques: a high-throughput nano-LC-IMS-TOF separation of peptides arising from a Drosophila protein extract. Anal Chem (2003) 1.54
Selective deficits in the expression of striatal-enriched mRNAs in Huntington's disease. J Neurochem (2006) 1.46
Proteomic analysis of protein expression and oxidative modification in r6/2 transgenic mice: a model of Huntington disease. Mol Cell Proteomics (2005) 1.25
Hyperactive striatal neurons in symptomatic Huntington R6/2 mice: variations with behavioral state and repeated ascorbate treatment. Neuroscience (2005) 1.24
Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry. J Proteome Res (2004) 1.17
Mapping the proteome of Drosophila melanogaster: analysis of embryos and adult heads by LC-IMS-MS methods. J Proteome Res (2005) 1.10
Developing liquid chromatography ion mobility mass spectometry techniques. Expert Rev Proteomics (2005) 1.08
Development of high throughput dispersive LC-ion mobility-TOFMS techniques for analysing the human plasma proteome. Brief Funct Genomic Proteomic (2004) 1.08
Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy. J Proteome Res (2006) 1.08
Proteome profiling for assessing diversity: analysis of individual heads of Drosophila melanogaster using LC-ion mobility-MS. J Proteome Res (2005) 1.03
Proteomics in 2002: a year of technical development and wide-ranging applications. Anal Chem (2003) 1.01
DNA microarray analysis of striatal gene expression in symptomatic transgenic Huntington's mice (R6/2) reveals neuroinflammation and insulin associations. Brain Res (2006) 0.99
Alterations in the mouse and human proteome caused by Huntington's disease. Mol Cell Proteomics (2002) 0.95
Systematic uncovering of multiple pathways underlying the pathology of Huntington disease by an acid-cleavable isotope-coded affinity tag approach. Mol Cell Proteomics (2007) 0.94
Protein expression in a Drosophila model of Parkinson's disease. J Proteome Res (2007) 0.93
Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models. Neurosci Lett (2000) 0.87
Recent liquid chromatographic-(tandem) mass spectrometric applications in proteomics. J Chromatogr A (2003) 0.87
Integrated genomic/proteomic analysis. Anal Chem (1999) 0.83
Engineered modeling and the secrets of Parkinson's disease. Trends Neurosci (2001) 0.77
An IMS-IMS analogue of MS-MS. Anal Chem (2006) 2.68
A computational approach toward label-free protein quantification using predicted peptide detectability. Bioinformatics (2006) 2.48
Toward plasma proteome profiling with ion mobility-mass spectrometry. J Proteome Res (2006) 2.18
IMS-IMS and IMS-IMS-IMS/MS for separating peptide and protein fragment ions. Anal Chem (2006) 2.05
Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats. J Neurosci (2009) 2.05
Mapping the human plasma proteome by SCX-LC-IMS-MS. J Am Soc Mass Spectrom (2007) 1.94
Biomolecule analysis by ion mobility spectrometry. Annu Rev Anal Chem (Palo Alto Calif) (2008) 1.89
High-resolution ion cyclotron mobility spectrometry. Anal Chem (2009) 1.56
Development of high-sensitivity ion trap ion mobility spectrometry time-of-flight techniques: a high-throughput nano-LC-IMS-TOF separation of peptides arising from a Drosophila protein extract. Anal Chem (2003) 1.54
Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption in alcohol-preferring rats. Alcohol Alcohol (2011) 1.52
Lifetime proteomic profiling of an A30P alpha-synuclein Drosophila model of Parkinson's disease. J Proteome Res (2007) 1.48
Repeated cocaine self-administration alters processing of cocaine-related information in rat prefrontal cortex. J Neurosci (2006) 1.41
Lidocaine inactivation of ventral subiculum attenuates cocaine-seeking behavior in rats. J Neurosci (2003) 1.41
Evidence for many resolvable structures within conformation types of electrosprayed ubiquitin ions. J Phys Chem B (2006) 1.39
The role of prefrontal cortex D1-like and D2-like receptors in cocaine-seeking behavior in rats. Psychopharmacology (Berl) (2004) 1.38
Resolving and assigning N-linked glycan structural isomers from ovalbumin by IMS-MS. J Am Soc Mass Spectrom (2008) 1.37
Overtone mobility spectrometry: part 1. Experimental observations. J Am Soc Mass Spectrom (2008) 1.32
Resolution and structural transitions of elongated states of ubiquitin. J Am Soc Mass Spectrom (2006) 1.29
Dysregulated information processing by medium spiny neurons in striatum of freely behaving mouse models of Huntington's disease. J Neurophysiol (2008) 1.28
Coupling ion mobility separations, collisional activation techniques, and multiple stages of MS for analysis of complex peptide mixtures. Anal Chem (2002) 1.22
Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. J Biomed Sci (2010) 1.19
Number of solution states of bradykinin from ion mobility and mass spectrometry measurements. J Am Chem Soc (2011) 1.18
Altered information processing in the prefrontal cortex of Huntington's disease mouse models. J Neurosci (2008) 1.18
Ionotropic glutamate receptors in the ventral tegmental area regulate cocaine-seeking behavior in rats. Neuropsychopharmacology (2005) 1.18
Transfer of structural elements from compact to extended states in unsolvated ubiquitin. J Am Chem Soc (2006) 1.15
Evidence for unfolding and refolding of gas-phase cytochrome C ions in a Paul trap. J Am Soc Mass Spectrom (2005) 1.14
Dissociation of different conformations of ubiquitin ions. J Am Soc Mass Spectrom (2002) 1.14
Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior. J Neurosci (2013) 1.12
Overtone mobility spectrometry: part 2. Theoretical considerations of resolving power. J Am Soc Mass Spectrom (2009) 1.11
Environmental enrichment reduces impulsivity during appetitive conditioning. Physiol Behav (2006) 1.10
A split-field drift tube for separation and efficient fragmentation of biomolecular ions. Anal Chem (2003) 1.10
Mapping the proteome of Drosophila melanogaster: analysis of embryos and adult heads by LC-IMS-MS methods. J Proteome Res (2005) 1.10
Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease. Behav Brain Res (2007) 1.09
Developing liquid chromatography ion mobility mass spectometry techniques. Expert Rev Proteomics (2005) 1.08
Development of high throughput dispersive LC-ion mobility-TOFMS techniques for analysing the human plasma proteome. Brief Funct Genomic Proteomic (2004) 1.08
Development of high-throughput liquid chromatography injected ion mobility quadrupole time-of-flight techniques for analysis of complex peptide mixtures. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 1.07
A scanning frequency mode for ion cyclotron mobility spectrometry. Anal Chem (2010) 1.07
Conformation types of ubiquitin [M+8H]8+ Ions from water:methanol solutions: evidence for the N and A States in aqueous solution. J Phys Chem B (2012) 1.06
Characterizing intermediates along the transition from polyproline I to polyproline II using ion mobility spectrometry-mass spectrometry. J Am Chem Soc (2014) 1.06
From solution to the gas phase: stepwise dehydration and kinetic trapping of substance P reveals the origin of peptide conformations. J Am Chem Soc (2013) 1.05
Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics. J Bacteriol (2010) 1.05
Ion mobility analysis of molecular dynamics. Annu Rev Phys Chem (2013) 1.05
Nanoflow LC/ion mobility/CID/TOF for proteomics: analysis of a human urinary proteome. J Proteome Res (2003) 1.04
Resolving isomeric peptide mixtures: a combined HPLC/ion mobility-TOFMS analysis of a 4000-component combinatorial library. Anal Chem (2002) 1.03
Evidence for a quasi-equilibrium distribution of states for bradykinin [M + 3H]3+ ions in the gas phase. J Phys Chem B (2010) 1.03
Proteome profiling for assessing diversity: analysis of individual heads of Drosophila melanogaster using LC-ion mobility-MS. J Proteome Res (2005) 1.03
Role of cerebral cortex in the neuropathology of Huntington's disease. Front Neural Circuits (2013) 1.02
An ion mobility/ion trap/photodissociation instrument for characterization of ion structure. J Am Soc Mass Spectrom (2011) 1.02
Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes. Basal Ganglia (2012) 1.02
Cis-trans isomerizations of proline residues are key to bradykinin conformations. J Am Chem Soc (2013) 1.01
Context-dependent behavioural and neuronal sensitization in striatum to MDMA (ecstasy) administration in rats. Eur J Neurosci (2006) 1.01
Determination of cross sections by overtone mobility spectrometry: evidence for loss of unstable structures at higher overtones. J Phys Chem B (2010) 1.01
Cis-trans signatures of proline-containing tryptic peptides in the gas phase. Anal Chem (2002) 1.00
Assessing the peak capacity of IMS-IMS separations of tryptic peptide ions in He at 300 K. Anal Chem (2007) 1.00
Development of field modulation in a split-field drift tube for high-throughput multidimensional separations. J Proteome Res (2005) 1.00
Wireless transmission of fast-scan cyclic voltammetry at a carbon-fiber microelectrode: proof of principle. J Neurosci Methods (2004) 1.00
Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington's disease. Behav Brain Res (2009) 0.99
Extracellular ascorbate modulates glutamate dynamics: role of behavioral activation. BMC Neurosci (2007) 0.99
Dysregulated Neuronal Activity Patterns Implicate Corticostriatal Circuit Dysfunction in Multiple Rodent Models of Huntington's Disease. Front Syst Neurosci (2011) 0.98
Controlled formation of peptide bonds in the gas phase. J Am Chem Soc (2011) 0.97
Modeling fast dopamine neurotransmission in the nucleus accumbens during behavior. Behav Brain Res (2002) 0.96
Ion trapping for ion mobility spectrometry measurements in a cyclical drift tube. Anal Chem (2013) 0.95
Charge-remote fragmentation of lithiated fatty acids on a TOF-TOF instrument using matrix-ionization. J Am Soc Mass Spectrom (2007) 0.95
Nanoflow LC/IMS-MS and LC/IMS-CID/MS of protein mixtures. J Am Soc Mass Spectrom (2004) 0.94
Differential environmental exposure alters NMDA but not AMPA receptor subunit expression in nucleus accumbens core and shell. Brain Res (2005) 0.93
Altered neural and behavioral dynamics in Huntington's disease: an entropy conservation approach. PLoS One (2012) 0.93
Ion mobility spectrometry/mass spectrometry snapshots for assessing the molecular compositions of complex polymeric systems. Anal Chem (2008) 0.93
Protein expression in a Drosophila model of Parkinson's disease. J Proteome Res (2007) 0.93
Development of a high-throughput IMS-IMS-MS approach for analyzing mixtures of biomolecules. J Proteomics (2008) 0.92
Temperature-dependent H/D exchange of compact and elongated cytochrome c ions in the gas phase. J Am Soc Mass Spectrom (2002) 0.92
Delineating diseases by IMS-MS profiling of serum N-linked glycans. J Proteome Res (2011) 0.92
Acute effects of 3,4-methylenedioxymethamphetamine on striatal single-unit activity and behavior in freely moving rats: differential involvement of dopamine D(1) and D(2) receptors. Brain Res (2003) 0.92
Coupling desorption electrospray ionization with ion mobility/mass spectrometry for analysis of protein structure: evidence for desorption of folded and denatured States. J Phys Chem B (2006) 0.91
Reinstatement of MDMA (ecstasy) seeking by exposure to discrete drug-conditioned cues. Pharmacol Biochem Behav (2007) 0.91
Role of 5-HT2A and 5-HT2C/B receptors in the acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on striatal single-unit activity and locomotion in freely moving rats. Psychopharmacology (Berl) (2005) 0.91
Dysfunctional behavioral modulation of corticostriatal communication in the R6/2 mouse model of Huntington's disease. PLoS One (2012) 0.91
Exploring crown ethers as shift reagents for ion mobility spectrometry. Anal Chem (2006) 0.91
Alteration of selective neurotransmitters in fetal brains of prenatally alcohol-treated C57BL/6 mice: quantitative analysis using liquid chromatography/tandem mass spectrometry. Int J Dev Neurosci (2010) 0.90
Subthalamic and striatal neurons concurrently process motor, limbic, and associative information in rats performing an operant task. J Neurophysiol (2006) 0.90
Improving the efficiency of IMS-IMS by a combing technique. Anal Chem (2008) 0.90
Using ion mobility data to improve peptide identification: intrinsic amino acid size parameters. J Proteome Res (2011) 0.89
Examining the proteome of Drosophila across organism lifespan. J Proteome Res (2007) 0.89
Extracted Fragment Ion Mobility Distributions: A New Method for Complex Mixture Analysis. Int J Mass Spectrom (2012) 0.88
Overtone mobility spectrometry: part 4. OMS-OMS analyses of complex mixtures. J Am Soc Mass Spectrom (2011) 0.88
Isotopic effect on ion mobility and separation of isotopomers by high-field ion mobility spectrometry. Anal Chem (2010) 0.88
On the dynamics of fragment isomerization in collision-induced dissociation of peptides. J Phys Chem A (2008) 0.88
Combinatorial libraries of synthetic peptides as a model for shotgun proteomics. Anal Chem (2010) 0.88
Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease. Mol Cell Proteomics (2008) 0.88
Dissociation of core and shell single-unit activity in the nucleus accumbens in free-choice novelty. Behav Brain Res (2004) 0.87
Solution dependence of the collisional activation of ubiquitin [M + 7H](7+) ions. J Am Soc Mass Spectrom (2014) 0.87
Conformational studies of Zn-ligand-hexose diastereomers using ion mobility measurements and density functional theory calculations. J Am Soc Mass Spectrom (2002) 0.87
Mannose7 glycan isomer characterization by IMS-MS/MS analysis. J Am Soc Mass Spectrom (2012) 0.87
Fast and accurate identification of semi-tryptic peptides in shotgun proteomics. Bioinformatics (2007) 0.86
Resolving oligomers from fully grown polymers with IMS-MS. Anal Chem (2007) 0.86
A new perspective on behavioral inconsistency and neural noise in aging: compensatory speeding of neural communication. Front Aging Neurosci (2012) 0.86