Cre-estrogen receptor-mediated hepatitis C virus structural protein expression in mice.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 2104783)

Published in J Virol Methods on July 12, 2007

Authors

Batbayar Tumurbaatar1, Yixiao Sun, Tehsheng Chan, Jiaren Sun

Author Affiliations

1: Department of Microbiology and Immunology and Center for Hepatitis Research Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1019, USA.

Articles cited by this

Global epidemiology of hepatitis C virus infection. Lancet Infect Dis (2005) 16.44

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol (2002) 13.87

Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ (2004) 9.96

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther (1999) 8.28

Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature (2005) 5.50

Unravelling hepatitis C virus replication from genome to function. Nature (2005) 5.25

The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med (1998) 4.48

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology (2002) 4.34

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci U S A (2001) 3.06

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology (2002) 3.02

Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. J Virol (2005) 2.85

Apoptosis: the nexus of liver injury and fibrosis. Hepatology (2004) 2.70

Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury. Hepatology (2004) 2.41

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J Virol (2002) 2.39

Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem (2005) 2.21

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses. Gastroenterology (2004) 2.18

Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol (2005) 2.14

Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion. Oncogene (2005) 2.02

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. Immunity (1999) 1.98

Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology (2005) 1.95

Mechanisms of liver injury. III. Oxidative stress in the pathogenesis of hepatitis C virus. Am J Physiol Gastrointest Liver Physiol (2006) 1.89

The ER stress pathway involving CHOP is activated in the lungs of LPS-treated mice. J Biochem (2005) 1.84

Chronic hepatitis C in patients with persistently normal alanine transaminase levels. Clin Gastroenterol Hepatol (2006) 1.77

Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation. J Virol (1999) 1.72

Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein. J Virol (1999) 1.52

Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding. Alcohol Clin Exp Res (2005) 1.49

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK. J Virol (2003) 1.45

Apoptosis in hepatitis C virus infection. Cell Death Differ (2003) 1.28

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury. Hepatology (2004) 1.25

The HCV core protein acts as a positive regulator of fas-mediated apoptosis in a human lymphoblastoid T cell line. Virology (2000) 1.23

Liver cell apoptosis in chronic hepatitis C correlates with histological but not biochemical activity or serum HCV-RNA levels. Hepatology (2000) 1.21

Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway. J Immunol (2005) 1.17

The extent of liver steatosis in chronic hepatitis C virus infection is mirrored by caspase activity in serum. Hepatology (2005) 1.10

Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system. J Biol Chem (1998) 1.09

Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins. J Biol Chem (2001) 1.05

Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein. Virology (2006) 1.02

Hepatitis C virus f protein is a short-lived protein associated with the endoplasmic reticulum. J Virol (2003) 1.01

Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis. Hepatology (2005) 0.99

Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. J Med Virol (2004) 0.99

Dysregulation of apoptosis as a mechanism of liver disease: an overview. Semin Liver Dis (1998) 0.99

Apoptosis of activated CD4+ and CD8+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction. Virology (2005) 0.95

Cytotoxic T lymphocytes derived from patients with chronic hepatitis C virus infection kill bystander cells via Fas-FasL interaction. J Virol (2004) 0.88

An apoptosis biomarker goes to the HCV clinic. Hepatology (2004) 0.87

Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. J Gen Virol (2005) 0.86

The immunologic basis for hepatitis C infection. Curr Opin Gastroenterol (2004) 0.86

Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury. J Virol (2005) 0.83

Apoptotic cell death does not parallel other indicators of liver damage in chronic hepatitis C patients. J Viral Hepat (2000) 0.81

Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes. Mol Cells (2002) 0.81

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology (2002) 3.02

Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J Biol Chem (2005) 2.21

Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Infect Immun (2003) 1.74

Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver. Gastroenterology (2011) 1.52

CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection. J Immunol (2005) 1.46

Sand fly saliva enhances Leishmania amazonensis infection by modulating interleukin-10 production. Infect Immun (2004) 1.35

Analysis of T helper cell responses during infection with Leishmania amazonensis. Am J Trop Med Hyg (2002) 1.28

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J Immunol (2010) 1.06

IL-33 induces nuocytes and modulates liver injury in viral hepatitis. J Immunol (2013) 1.01

Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol (2012) 0.95

Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice. Hepatology (2011) 0.89

T-cell receptor complex is essential for Fas signal transduction. Proc Natl Acad Sci U S A (2010) 0.86

Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol (2014) 0.82

Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2. J Virol (2009) 0.81

Spatial trend and pollution assessment of total mercury and methylmercury pollution in the Pearl River Delta soil, South China. Chemosphere (2012) 0.80

Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance. J Innate Immun (2015) 0.78

Aberrant transcription and post-transcriptional processing of hepatitis C virus non-structural genes in transgenic mice. Transgenic Res (2011) 0.76

Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity. J Gastroenterol Hepatol (2014) 0.76