Takashi Yamamura

Author PubWeight™ 115.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002 4.34
2 Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. Proc Natl Acad Sci U S A 2005 2.83
3 Thyrotrophin in the pars tuberalis triggers photoperiodic response. Nature 2008 2.60
4 The regulatory role of natural killer cells in multiple sclerosis. Brain 2004 1.84
5 Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype. J Immunol 2007 1.77
6 Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in preovulatory ovarian follicles. Endocrinology 2007 1.74
7 Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide. Arthritis Rheum 2004 1.74
8 Invariant V(alpha)19i T cells regulate autoimmune inflammation. Nat Immunol 2006 1.72
9 Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat Med 2007 1.69
10 Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds. Nature 2003 1.67
11 Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis. J Immunol 2007 1.67
12 Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: a pilot study. Neurology 2014 1.62
13 The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells. J Clin Invest 2004 1.61
14 Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. J Clin Invest 2010 1.60
15 Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc Natl Acad Sci U S A 2011 1.60
16 Th17 Cells and autoimmune encephalomyelitis (EAE/MS). Allergol Int 2008 1.54
17 A Structural basis for the association of DAP12 with mouse, but not human, NKG2D. J Immunol 2004 1.46
18 Cannabinoids and the immune system: potential for the treatment of inflammatory diseases? J Neuroimmunol 2005 1.45
19 Back to the future for multiple sclerosis therapy: focus on current and emerging disease-modifying therapeutic strategies. Immunotherapy 2009 1.39
20 Another view of T cell antigen recognition: cooperative engagement of glycolipid antigens by Va14Ja18 natural T(iNKT) cell receptor [corrected]. J Immunol 2003 1.38
21 NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora. Am J Pathol 2008 1.35
22 Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis. Int Immunol 2011 1.33
23 Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy. JAMA Neurol 2013 1.30
24 Natural killer T cells accelerate atherogenesis in mice. Blood 2004 1.28
25 CD4+ NKT cells, but not conventional CD4+ T cells, are required to generate efferent CD8+ T regulatory cells following antigen inoculation in an immune-privileged site. J Immunol 2003 1.25
26 Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission. Int Immunol 2003 1.21
27 Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Neurobiol Dis 2005 1.20
28 Accumulation of Valpha7.2-Jalpha33 invariant T cells in human autoimmune inflammatory lesions in the nervous system. Int Immunol 2004 1.20
29 Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab. Mod Rheumatol 2012 1.17
30 Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol 2007 1.16
31 Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo. Neuropathology 2007 1.14
32 T cell gene expression profiling identifies distinct subgroups of Japanese multiple sclerosis patients. J Neuroimmunol 2006 1.13
33 IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. Blood 2005 1.12
34 NKT cells are critical for the initiation of an inflammatory bowel response against Toxoplasma gondii. J Immunol 2005 1.09
35 Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis. Arthritis Rheum 2012 1.08
36 Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo. J Immunol 2003 1.08
37 Stimulation of host NKT cells by synthetic glycolipid regulates acute graft-versus-host disease by inducing Th2 polarization of donor T cells. J Immunol 2005 1.06
38 Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. Am J Pathol 2009 1.05
39 Photoperiodic regulation of type 2 deiodinase gene in Djungarian hamster: possible homologies between avian and mammalian photoperiodic regulation of reproduction. Endocrinology 2004 1.05
40 Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines. Proc Natl Acad Sci U S A 2008 1.04
41 Preferential T(h)2 polarization by OCH is supported by incompetent NKT cell induction of CD40L and following production of inflammatory cytokines by bystander cells in vivo. Int Immunol 2005 1.04
42 Hypothalamic expression of thyroid hormone-activating and -inactivating enzyme genes in relation to photorefractoriness in birds and mammals. Am J Physiol Regul Integr Comp Physiol 2007 1.03
43 Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis. J Neuropathol Exp Neurol 2005 1.03
44 Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice. Inflamm Bowel Dis 2005 1.02
45 Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice. J Autoimmun 2004 1.02
46 The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models. Arthritis Rheum 2005 1.01
47 Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway. Brain 2006 1.00
48 Relevance of neuropeptide Y for the neuroimmune crosstalk. J Neuroimmunol 2003 0.99
49 Rapid identification of 14-3-3-binding proteins by protein microarray analysis. J Neurosci Methods 2005 0.99
50 Murine CD160, Ig-like receptor on NK cells and NKT cells, recognizes classical and nonclassical MHC class I and regulates NK cell activation. J Immunol 2005 0.98
51 Suppression of experimental autoimmune encephalomyelitis by ghrelin. J Immunol 2009 0.97
52 Therapeutic potential of glycolipid ligands for natural killer (NK) T cells in the suppression of autoimmune diseases. Curr Drug Targets Immune Endocr Metabol Disord 2005 0.96
53 The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR. J Immunol 2006 0.96
54 Treatment of neuromyelitis optica: current debate. Ther Adv Neurol Disord 2008 0.95
55 Heterozygous null mutation of myelin P0 protein enhances susceptibility to autoimmune neuritis targeting P0 peptide. Eur J Immunol 2003 0.94
56 Long-day suppressed expression of type 2 deiodinase gene in the mediobasal hypothalamus of the Saanen goat, a short-day breeder: implication for seasonal window of thyroid hormone action on reproductive neuroendocrine axis. Endocrinology 2005 0.93
57 Activation of invariant natural killer T cells by synthetic glycolipid ligands suppresses autoantibody-induced arthritis. Arthritis Rheum 2007 0.93
58 Molecular network analysis of T-cell transcriptome suggests aberrant regulation of gene expression by NF-kappaB as a biomarker for relapse of multiple sclerosis. Dis Markers 2008 0.92
59 Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis. J Neuroimmunol 2007 0.92
60 More sympathy for autoimmunity with neuropeptide Y? Trends Immunol 2004 0.90
61 Differential expression of CD11c by peripheral blood NK cells reflects temporal activity of multiple sclerosis. J Immunol 2006 0.90
62 The 14-3-3 protein epsilon isoform expressed in reactive astrocytes in demyelinating lesions of multiple sclerosis binds to vimentin and glial fibrillary acidic protein in cultured human astrocytes. Am J Pathol 2004 0.90
63 [Validation of the Japanese-translated version Multiple Sclerosis Quality of Life-54 instrument]. Rinsho Shinkeigaku 2004 0.89
64 Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania. Eur J Immunol 2008 0.89
65 A novel compound heterozygous mutation in the DAP12 gene in a patient with Nasu-Hakola disease. J Neurol Sci 2006 0.89
66 Microarray analysis identifies a set of CXCR3 and CCR2 ligand chemokines as early IFNbeta-responsive genes in peripheral blood lymphocytes in vitro: an implication for IFNbeta-related adverse effects in multiple sclerosis. BMC Neurol 2006 0.89
67 Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica. PLoS One 2013 0.89
68 Kisspeptin as a master player in the central control of reproduction in mammals: an overview of kisspeptin research in domestic animals. Anim Sci J 2013 0.88
69 Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling. PLoS One 2013 0.87
70 Gene expression profile following stable expression of the cellular prion protein. Cell Mol Neurobiol 2004 0.86
71 CCR2(+)CCR5(+) T cells produce matrix metalloproteinase-9 and osteopontin in the pathogenesis of multiple sclerosis. J Immunol 2012 0.86
72 Electrophysiological and morphological evidence for synchronized GnRH pulse generator activity among Kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in goats. J Reprod Dev 2012 0.85
73 New-onset type 1 diabetes mellitus and anti-aquaporin-4 antibody positive optic neuritis associated with type 1 interferon therapy for chronic hepatitis C. Intern Med 2012 0.85
74 Retinoid signals and Th17-mediated pathology. Nihon Rinsho Meneki Gakkai Kaishi 2009 0.83
75 Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs. Bioorg Med Chem Lett 2007 0.83
76 A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation. Arthritis Res Ther 2012 0.83
77 Human astrocytes express 14-3-3 sigma in response to oxidative and DNA-damaging stresses. Neurosci Res 2006 0.83
78 Sex steroid-induced neuroplasticity and behavioral activation in birds. Eur J Neurosci 2010 0.82
79 Neuromyelitis optica/Devic's disease: gene expression profiling of brain lesions. Neuropathology 2008 0.82
80 Development of a culture system to induce microglia-like cells from haematopoietic cells. Neuropathol Appl Neurobiol 2014 0.82
81 Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis. J Neuroimmunol 2003 0.82
82 Heterogeneity and continuum of multiple sclerosis phenotypes in Japanese according to the results of the fourth nationwide survey. J Neurol Sci 2009 0.81
83 New cyclooxygenase-2 inhibitors for treatment of experimental autoimmune neuritis. Muscle Nerve 2002 0.81
84 A population of kisspeptin/neurokinin B neurons in the arcuate nucleus may be the central target of the male effect phenomenon in goats. PLoS One 2013 0.80
85 GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A. J Biol Chem 2011 0.80
86 Psychological stress increases human T cell apoptosis in vitro. Neuroimmunomodulation 2003 0.79
87 Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via an iNKT cell-dependent mechanism. Am J Pathol 2009 0.79
88 Role of NK cells and invariant NKT cells in multiple sclerosis. Results Probl Cell Differ 2010 0.79
89 Molecular mechanism of photoperiodic time measurement in the brain of Japanese quail. Chronobiol Int 2006 0.79
90 Localization of NK1.1(+) invariant Valpha19 TCR(+) cells in the liver with potential to promptly respond to TCR stimulation. Immunol Lett 2008 0.79
91 Apathy/depression, but not subjective fatigue, is related with cognitive dysfunction in patients with multiple sclerosis. BMC Neurol 2014 0.79
92 Abnormalities of cerebral blood flow in multiple sclerosis: a pseudocontinuous arterial spin labeling MRI study. Magn Reson Imaging 2013 0.79
93 Involvement of transforming growth factor alpha in the photoperiodic regulation of reproduction in birds. Endocrinology 2007 0.78
94 Aberrant transcriptional regulatory network in T cells of multiple sclerosis. Neurosci Lett 2007 0.78
95 Total synthesis of an immunosuppressive glycolipid, (2S,3S,4R)-1-O- (alpha-d-galactosyl)-2- tetracosanoylamino-1,3,4-nonanetriol. J Org Chem 2005 0.78
96 Red jungle fowl (Gallus gallus) as a model for studying the molecular mechanism of seasonal reproduction. Anim Sci J 2009 0.78
97 Peripheral clock gene expression in CS mice with bimodal locomotor rhythms. Neurosci Res 2006 0.78
98 Tissue culture methods to study neurological disorders: establishment of immortalized Schwann cells from murine disease models. Neuropathology 2003 0.78
99 Epiregulin is critical for the acinar cell regeneration of the submandibular gland in a mouse duct ligation model. J Oral Pathol Med 2013 0.78
100 Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile. Bioorg Med Chem 2012 0.78
101 Synthetic glycolipid ligands for human iNKT cells as potential therapeutic agents for immunotherapy. Curr Med Chem 2008 0.77
102 The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein. J Neuropathol Exp Neurol 2005 0.76
103 Therapeutic potential of CD1d-restricted invariant natural killer T cell-based treatment for autoimmune diseases. Int Rev Immunol 2007 0.76
104 Plasmablast in the pathology of multiple sclerosis. Nihon Rinsho Meneki Gakkai Kaishi 2015 0.76
105 Increase of Ki-67+ natural killer cells in multiple sclerosis patients treated with interferon-β and interferon-β combined with low-dose oral steroids. J Neuroimmunol 2011 0.75
106 [Nephrotic syndrome in multiple sclerosis patients who had undergone long-term interferon β-1b therapy]. Rinsho Shinkeigaku 2013 0.75
107 [Cell-mediated immunity in neuroimmunological disorders]. Nihon Rinsho 2015 0.75
108 [Pathogenesis of chronic inflammatory demyelinating polyneuropathy]. Nihon Rinsho 2013 0.75
109 Potential of targeting natural killer T cells for the treatment of autoimmune diseases. Mod Rheumatol 2004 0.75
110 Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation. J Med Chem 2014 0.75
111 [Experimental animal model of multiple sclerosis--transverse investigation of MS pathogenesis for therapeutic intervention]. Nihon Rinsho 2014 0.75
112 [Hypothetical view on the environmental factors, Th1/Th2 balance, and disease phenotype of MS/EAE]. Rinsho Shinkeigaku 2002 0.75
113 [Identification of a possible therapeutic target through pathogenic T cell analysis of multiple sclerosis]. Nihon Rinsho Meneki Gakkai Kaishi 2009 0.75
114 Ghrelin: friend or foe for neuroinflammation. Discov Med 2009 0.75
115 [Molecular targeted therapy]. Brain Nerve 2014 0.75
116 [Experimental autoimmune encephalomyelitis: crosstalk with immunology and therapy]. Nihon Rinsho Meneki Gakkai Kaishi 2014 0.75
117 [Animal models for multiple sclerosis]. Nihon Rinsho 2015 0.75
118 B-cell-directed therapy: which B cells should be targeted and how? Immunotherapy 2012 0.75
119 [Multiple sclerosis: a disease mediated by autoimmune mechanism]. Rinsho Shinkeigaku 2008 0.75
120 [Programs for Continuing Medical Education: A session; 6. Advances in basic research and therapy of multiple sclerosis]. Nihon Naika Gakkai Zasshi 2015 0.75
121 An assessment of mast cells and myofibroblasts in denture-induced fibrous hyperplasia. J Oral Pathol Med 2013 0.75