Michael Wigler

Author PubWeight™ 215.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Large-scale copy number polymorphism in the human genome. Science 2004 34.64
2 Strong association of de novo copy number mutations with autism. Science 2007 27.84
3 Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 2004 24.18
4 Tumour evolution inferred by single-cell sequencing. Nature 2011 19.13
5 Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell 2006 12.72
6 Annotating large genomes with exact word matches. Genome Res 2003 11.07
7 De novo gene disruptions in children on the autistic spectrum. Neuron 2012 9.69
8 Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res 2003 7.86
9 Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. Am J Hum Genet 2008 7.13
10 Inferring tumor progression from genomic heterogeneity. Genome Res 2009 6.09
11 Rare de novo and transmitted copy-number variation in autistic spectrum disorders. Neuron 2011 5.78
12 An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 2008 5.47
13 Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 2011 4.66
14 Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res 2006 4.25
15 A unified genetic theory for sporadic and inherited autism. Proc Natl Acad Sci U S A 2007 3.47
16 High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Genome Res 2009 3.08
17 A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A 2012 2.85
18 DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes Dev 2008 2.60
19 Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell 2009 2.54
20 Genome-wide copy number analysis of single cells. Nat Protoc 2012 2.47
21 Recurrent DNA copy number variation in the laboratory mouse. Nat Genet 2007 2.40
22 Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood 2008 2.35
23 A versatile statistical analysis algorithm to detect genome copy number variation. Proc Natl Acad Sci U S A 2004 1.88
24 Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc Natl Acad Sci U S A 2011 1.82
25 DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables. Mol Oncol 2010 1.33
26 PROBER: oligonucleotide FISH probe design software. Bioinformatics 2006 1.20
27 Application of ROMA (representational oligonucleotide microarray analysis) to patients with cytogenetic rearrangements. Genet Med 2005 1.15
28 The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease. Hum Genet 2013 1.15
29 Distribution of short paired duplications in mammalian genomes. Proc Natl Acad Sci U S A 2004 1.05
30 Target inference from collections of genomic intervals. Proc Natl Acad Sci U S A 2013 1.02
31 Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens. Proc Natl Acad Sci U S A 2006 1.01
32 Copy-number variants in patients with a strong family history of pancreatic cancer. Cancer Biol Ther 2007 0.99
33 Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A 2006 0.99
34 Rare de novo germline copy-number variation in testicular cancer. Am J Hum Genet 2012 0.87
35 Reducing system noise in copy number data using principal components of self-self hybridizations. Proc Natl Acad Sci U S A 2011 0.87
36 A sense of life: computational and experimental investigations with models of biochemical and evolutionary processes. OMICS 2003 0.77
37 The cancer stem cell: cell type or cell state? Cytometry A 2012 0.77
38 Quantitative multigene FISH on breast carcinomas identifies der(1;16)(q10;p10) as an early event in luminal A tumors. Genes Chromosomes Cancer 2014 0.77
39 Corrigendum: Genome-wide copy number analysis of single cells. Nat Protoc 2016 0.75
40 Validation of S. pombe sequence assembly by microarray hybridization. J Comput Biol 2006 0.75