D Piwnica-Worms

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci U S A 1999 2.02
2 Multidrug resistance transporters and modulation. Curr Opin Oncol 2000 1.71
3 Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy. Oncogene 2006 1.70
4 Effect of mitochondrial and plasma membrane potentials on accumulation of hexakis (2-methoxyisobutylisonitrile) technetium(I) in cultured mouse fibroblasts. J Nucl Med 1990 1.52
5 Na/H exchange in cultured chick heart cells. pHi regulation. J Gen Physiol 1985 1.44
6 Uptake of the cation hexakis(2-methoxyisobutylisonitrile)-technetium-99m by human carcinoma cell lines in vitro. Cancer Res 1990 1.43
7 Intracellular water-specific MR of microbead-adherent cells: the HeLa cell intracellular water exchange lifetime. NMR Biomed 2008 1.35
8 Subcellular distribution and analysis of technetium-99m-MIBI in isolated perfused rat hearts. J Nucl Med 1992 1.34
9 Molecular imaging in vivo with PET and SPECT. Acad Radiol 2001 1.30
10 Novel Tat-peptide chelates for direct transduction of technetium-99m and rhenium into human cells for imaging and radiotherapy. Bioconjug Chem 2000 1.24
11 Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains. Biochemistry 2000 1.22
12 Overexpression of IRF9 confers resistance to antimicrotubule agents in breast cancer cells. Cancer Res 2001 1.15
13 The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects. Leukemia 2012 1.07
14 Intracellular pH regulation in cultured embryonic chick heart cells. Na(+)-dependent Cl-/HCO3- exchange. J Gen Physiol 1990 1.06
15 Modulation of the multidrug resistance P-glycoprotein: detection with technetium-99m-sestamibi in vivo. J Nucl Med 1997 1.06
16 Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation. Oncogene 2010 1.05
17 Characterization of phosphine complexes of technetium(III) as transport substrates of the multidrug resistance P-glycoprotein and functional markers of P-glycoprotein at the blood-brain barrier. Biochemistry 1997 1.04
18 Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin. Biochem Pharmacol 2000 1.02
19 Intracellular water specific MR of microbead-adherent cells: HeLa cell intracellular water diffusion. Magn Reson Med 2008 0.99
20 Theoretical effects of transmembrane electroneutral exchange on membrane potential. J Gen Physiol 1984 0.99
21 Microfluorometric monitoring of pHi in cultured heart cells: Na+-H+ exchange. Am J Physiol 1983 0.98
22 Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol. J Biol Chem 1999 0.98
23 Transmembrane chloride flux in tissue-cultured chick heart cells. J Gen Physiol 1983 0.97
24 Metal complexes for therapy and diagnosis of drug resistance. Chem Rev 1999 0.97
25 (Na + K + 2Cl) cotransport in cultured embryonic chick heart cells. Am J Physiol 1987 0.92
26 Novel technetium (III)-Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein. J Nucl Med 1998 0.91
27 MDR1 P-glycoprotein reduces influx of substrates without affecting membrane potential. J Biol Chem 2001 0.91
28 Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo. Chem Biol 2000 0.90
29 Potassium-chloride cotransport in cultured chick heart cells. Am J Physiol 1985 0.90
30 Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations. J Med Chem 1996 0.89
31 Na/H exchange in cultured chick heart cells: secondary stimulation of electrogenic transport during recovery from intracellular acidosis. J Mol Cell Cardiol 1986 0.89
32 Chemical reaction-induced multi-molecular polarization (CRIMP). Chem Commun (Camb) 2014 0.88
33 Microprobe analysis of Tc-MIBI in heart cells: calculation of mitochondrial membrane potential. Am J Physiol 1993 0.85
34 Expression of recombinant human multidrug resistance P-glycoprotein in insect cells confers decreased accumulation of technetium-99m-sestamibi. J Nucl Med 1994 0.85
35 Decreased hepatic accumulation and enhanced esterification of cholesterol in mice deficient in mdr1a and mdr1b P-glycoproteins. J Lipid Res 2001 0.83
36 Novel hexakis(areneisonitrile)technetium(I) complexes as radioligands targeted to the multidrug resistance P-glycoprotein. J Med Chem 1995 0.81
37 Dynamic nature of the aortic regurgitant orifice area during diastole in patients with chronic aortic regurgitation. Circulation 1994 0.80
38 Aortic flow velocity patterns in chronic aortic regurgitation: implications for Doppler echocardiography. J Am Soc Echocardiogr 1997 0.80
39 Tumor receptor imaging: proceedings of the National Cancer Institute workshop, review of current work, and prospective for further investigations. Clin Cancer Res 1995 0.80
40 Effects of sodium-potassium pump inhibition and low sodium on membrane potential in cultured embryonic chick heart cells. J Physiol 1987 0.79
41 MDR1 gene-specific monoclonal antibody C494 cross-reacts with pyruvate carboxylase. Cancer Res 1994 0.79
42 Pharmacokinetic modeling of multidrug resistance P-glycoprotein transport of gamma-emitting substrates. Q J Nucl Med 1997 0.78
43 PET imaging of heat-inducible suicide gene expression in mice bearing head and neck squamous cell carcinoma xenografts. Cancer Gene Ther 2008 0.78
44 Reversal of multidrug resistance with LY335979: functional analysis of P-glycoprotein-mediated transport activity and its modulation in vivo. J Clin Pharmacol 2001 0.78
45 Characterization of functional assays of multidrug resistance P-glycoprotein transport activity. Leukemia 1997 0.78
46 Comparison of neutral and cationic myocardial perfusion agents: characteristics of accumulation in cultured cells. Int J Rad Appl Instrum B 1992 0.77
47 Physiologic criteria for electrogenic transport in tissue-cultured heart cells. Soc Gen Physiol Ser 1984 0.77
48 A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation. Anal Biochem 2007 0.77
49 Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes. J Biol Chem 1997 0.77
50 Multidrug resistance P-glycoprotein monoclonal antibody JSB-1 crossreacts with pyruvate carboxylase. J Histochem Cytochem 1995 0.77
51 A novel areneisonitrile Tc complex inhibits the transport activity of MDR P-glycoprotein. Nucl Med Biol 1998 0.76
52 Prospective double-blinded comparison of MR imaging and aortography in the preoperative evaluation of abdominal aortic aneurysms. J Vasc Interv Radiol 1992 0.76
53 Making sense out of anti-sense: challenges of imaging gene translation with radiolabeled oligonucleotides. J Nucl Med 1994 0.75
54 Interaction of (Na + K + 2 Cl) cotransport and the Na/K pump in cultured chick cardiac myocytes. Mol Cell Biochem 1989 0.75
55 Electroneutral Na/H exchange may depolarize the membrane potential in steady state. J Gen Physiol 1985 0.75
56 Membrane potential determination in large unilamellar vesicles with hexakis(2-methoxyisobutylisonitrile)technetium(I). Biochim Biophys Acta 1993 0.75
57 Chronic ear discharge in an elderly diabetic man. Invest Radiol 1986 0.75
58 Contrast media and radiopharmaceutical agents: regulatory issues. Acad Radiol 1995 0.75
59 Comparative effects of neutral dipolar compounds and lipophilic anions on technetium 99m-hexakis (2-methoxyisobutyl isonitrile) accumulation in cultured chick ventricular myocytes. Invest Radiol 1992 0.75