Michael Platten

Author PubWeight™ 64.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. Lancet Oncol 2012 6.20
2 An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 2011 4.63
3 SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo. Cancer Res 2004 2.35
4 Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. J Clin Oncol 2007 2.11
5 Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation. Neurology 2013 1.98
6 Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells 2009 1.72
7 ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. Acta Neuropathol 2014 1.66
8 MICA/NKG2D-mediated immunogene therapy of experimental gliomas. Cancer Res 2003 1.60
9 New (alternative) temozolomide regimens for the treatment of glioma. Neuro Oncol 2008 1.58
10 ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis. Acta Neuropathol 2013 1.58
11 Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathol 2013 1.49
12 Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. Acta Neuropathol 2014 1.42
13 Angiotensin II sustains brain inflammation in mice via TGF-beta. J Clin Invest 2010 1.39
14 Pathway inhibition: emerging molecular targets for treating glioblastoma. Neuro Oncol 2011 1.38
15 The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells. PLoS One 2011 1.32
16 Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle. PLoS Biol 2007 1.23
17 mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy. Proc Natl Acad Sci U S A 2013 1.20
18 Human epidermal growth factor receptor 2 testing in gastric carcinoma: issues related to heterogeneity in biopsies and resections. Histopathology 2011 1.16
19 IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO. Acta Neuropathol 2015 1.13
20 Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR. Oncotarget 2014 1.11
21 Bevacizumab does not increase the risk of remote relapse in malignant glioma. Ann Neurol 2011 1.10
22 A novel tool to analyze MRI recurrence patterns in glioblastoma. Neuro Oncol 2008 1.04
23 Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness. Clin Cancer Res 2011 1.03
24 Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression. Acta Neuropathol 2011 1.00
25 Multiple sclerosis: trapped in deadly glue. Nat Med 2005 0.97
26 Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathol 2015 0.97
27 Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1). Stem Cells Dev 2010 0.97
28 Gastrointestinal stromal tumours (GISTs): a clinicopathological and molecular study of 66 cases. Pathology 2005 0.97
29 Proximity ligation assay evaluates IDH1R132H presentation in gliomas. J Clin Invest 2015 0.97
30 Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective. Neuro Oncol 2013 0.95
31 A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. J Immunol 2005 0.94
32 The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress. Cancer Res 2013 0.92
33 Enzastaurin before and concomitant with radiation therapy, followed by enzastaurin maintenance therapy, in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation. Neuro Oncol 2013 0.90
34 Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma. J Neuroimmunol 2013 0.89
35 Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2013 0.88
36 Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase. PLoS One 2012 0.87
37 Towards optimizing the sequence of bevacizumab and nitrosoureas in recurrent malignant glioma. J Neurooncol 2014 0.84
38 Good maths is needed to understand CMV data in glioblastoma. Int J Cancer 2013 0.84
39 Does age matter? - A MRI study on peritumoral edema in newly diagnosed primary glioblastoma. BMC Cancer 2011 0.83
40 Suppression of human CD4+ T cell activation by 3,4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10. Biochem Pharmacol 2011 0.83
41 Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway. Glia 2014 0.82
42 Geriatric neuro-oncology: from mythology to biology. Curr Opin Neurol 2011 0.81
43 CMV infection and glioma, a highly controversial concept struggling in the clinical arena. Neuro Oncol 2014 0.80
44 Knowledge of HIV and factors associated with attitudes towards HIV among final-year medical students at Hanoi medical university in Vietnam. BMC Public Health 2014 0.79
45 Challenging cytomegalovirus data in glioblastoma. Neuro Oncol 2013 0.79
46 Defective p53 antiangiogenic signaling in glioblastoma. Neuro Oncol 2010 0.79
47 Expression of cell cycle regulatory proteins in endometrial adenocarcinoma: variations in conventional tumor areas and in microcystic, elongated and fragmented glands. Mod Pathol 2009 0.78
48 BRAF p.Val600Glu (V600E) mutation detection in thyroid fine needle aspiration cell block samples: a feasibility study. Pathology 2015 0.78
49 Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells. J Invest Dermatol 2013 0.78
50 Treatment of anaplastic glioma. Cancer Treat Res 2015 0.77
51 Extravascular migratory metastasis in gynaecological carcinosarcoma. Histopathology 2014 0.76
52 The aryl hydrocarbon receptor as a promoter of malignant glioma. Cell Cycle 2012 0.76
53 EGFRvIII vaccine in glioblastoma-InACT-IVe or not ReACTive enough? Neuro Oncol 2017 0.75
54 The promises of immunotherapy in gliomas. Curr Opin Neurol 2017 0.75