|
1
|
The order Herpesvirales.
|
Arch Virol
|
2008
|
3.41
|
|
2
|
Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1.
|
J Virol
|
2004
|
2.69
|
|
3
|
Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells.
|
Proc Natl Acad Sci U S A
|
2005
|
2.67
|
|
4
|
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
|
Proc Natl Acad Sci U S A
|
2008
|
2.64
|
|
5
|
Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex.
|
Proc Natl Acad Sci U S A
|
2007
|
2.37
|
|
6
|
Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects.
|
J Virol
|
2003
|
2.33
|
|
7
|
Infectious agents and cancer: criteria for a causal relation.
|
Semin Cancer Biol
|
2004
|
2.20
|
|
8
|
The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5a.
|
Proc Natl Acad Sci U S A
|
2003
|
2.12
|
|
9
|
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
|
Proc Natl Acad Sci U S A
|
2004
|
2.06
|
|
10
|
Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes.
|
Proc Natl Acad Sci U S A
|
2002
|
1.82
|
|
11
|
Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0.
|
J Virol
|
2003
|
1.78
|
|
12
|
ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.
|
Proc Natl Acad Sci U S A
|
2006
|
1.75
|
|
13
|
Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection.
|
Proc Natl Acad Sci U S A
|
2002
|
1.72
|
|
14
|
Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis.
|
Proc Natl Acad Sci U S A
|
2004
|
1.72
|
|
15
|
The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.
|
Proc Natl Acad Sci U S A
|
2006
|
1.68
|
|
16
|
Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins.
|
J Virol
|
2002
|
1.67
|
|
17
|
Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
|
Cancer Res
|
2007
|
1.65
|
|
18
|
The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
|
Proc Natl Acad Sci U S A
|
2004
|
1.62
|
|
19
|
The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene.
|
Proc Natl Acad Sci U S A
|
2002
|
1.51
|
|
20
|
Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus.
|
J Virol
|
2008
|
1.44
|
|
21
|
HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency-associated transcript and miRNAs.
|
Proc Natl Acad Sci U S A
|
2011
|
1.40
|
|
22
|
The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem.
|
J Virol
|
2008
|
1.40
|
|
23
|
Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.
|
J Virol
|
2004
|
1.39
|
|
24
|
Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction.
|
Proc Natl Acad Sci U S A
|
2002
|
1.39
|
|
25
|
The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene.
|
J Virol
|
2003
|
1.37
|
|
26
|
Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
|
J Virol
|
2006
|
1.35
|
|
27
|
Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
|
J Virol
|
2004
|
1.34
|
|
28
|
The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs.
|
Proc Natl Acad Sci U S A
|
2004
|
1.32
|
|
29
|
The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A.
|
J Virol
|
2006
|
1.31
|
|
30
|
The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.
|
J Virol
|
2005
|
1.30
|
|
31
|
Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
|
Proc Natl Acad Sci U S A
|
2010
|
1.29
|
|
32
|
Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1.
|
J Virol
|
2009
|
1.29
|
|
33
|
Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.
|
Clin Cancer Res
|
2012
|
1.29
|
|
34
|
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model.
|
Neuro Oncol
|
2005
|
1.26
|
|
35
|
The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1.
|
J Virol
|
2003
|
1.25
|
|
36
|
Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.
|
Proc Natl Acad Sci U S A
|
2003
|
1.25
|
|
37
|
Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.
|
J Virol
|
2002
|
1.25
|
|
38
|
Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptor.
|
Proc Natl Acad Sci U S A
|
2006
|
1.22
|
|
39
|
Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1.
|
J Virol
|
2006
|
1.21
|
|
40
|
Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
|
J Virol
|
2005
|
1.19
|
|
41
|
Disruption of HDAC/CoREST/REST repressor by dnREST reduces genome silencing and increases virulence of herpes simplex virus.
|
Proc Natl Acad Sci U S A
|
2010
|
1.19
|
|
42
|
Herpes simplex viruses: is a vaccine tenable?
|
J Clin Invest
|
2002
|
1.18
|
|
43
|
Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
|
Proc Natl Acad Sci U S A
|
2003
|
1.16
|
|
44
|
An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.
|
J Virol
|
2002
|
1.14
|
|
45
|
The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD.
|
J Virol
|
2003
|
1.13
|
|
46
|
Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA.
|
Proc Natl Acad Sci U S A
|
2007
|
1.12
|
|
47
|
Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
|
J Virol
|
2007
|
1.12
|
|
48
|
Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1.
|
Proc Natl Acad Sci U S A
|
2008
|
1.10
|
|
49
|
The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22.
|
J Virol
|
2011
|
1.09
|
|
50
|
Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
|
J Virol
|
2004
|
1.09
|
|
51
|
Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.
|
Genomics
|
2003
|
1.08
|
|
52
|
Induction of apoptosis accelerates reactivation of latent HSV-1 in ganglionic organ cultures and replication in cell cultures.
|
Proc Natl Acad Sci U S A
|
2012
|
1.07
|
|
53
|
U(S)3 and U(S)3.5 protein kinases of herpes simplex virus 1 differ with respect to their functions in blocking apoptosis and in virion maturation and egress.
|
J Virol
|
2006
|
1.06
|
|
54
|
Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene.
|
J Virol
|
2007
|
1.06
|
|
55
|
Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces.
|
Proc Natl Acad Sci U S A
|
2005
|
1.05
|
|
56
|
U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner.
|
J Virol
|
2002
|
1.04
|
|
57
|
Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.
|
Proc Natl Acad Sci U S A
|
2002
|
1.03
|
|
58
|
Glycoprotein M of herpes simplex virus 1 is incorporated into virions during budding at the inner nuclear membrane.
|
J Virol
|
2006
|
1.03
|
|
59
|
The CoREST/REST repressor is both necessary and inimical for expression of herpes simplex virus genes.
|
MBio
|
2010
|
1.02
|
|
60
|
Modulation of reactivation of latent herpes simplex virus 1 in ganglionic organ cultures by p300/CBP and STAT3.
|
Proc Natl Acad Sci U S A
|
2013
|
1.02
|
|
61
|
Role of cdk9 in the optimization of expression of the genes regulated by ICP22 of herpes simplex virus 1.
|
J Virol
|
2008
|
1.01
|
|
62
|
Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.
|
J Virol
|
2002
|
1.00
|
|
63
|
Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells.
|
J Virol
|
2005
|
1.00
|
|
64
|
ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
|
Proc Natl Acad Sci U S A
|
2009
|
0.99
|
|
65
|
Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein.
|
J Virol
|
2002
|
0.99
|
|
66
|
Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins.
|
Proc Natl Acad Sci U S A
|
2007
|
0.98
|
|
67
|
HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.
|
Proc Natl Acad Sci U S A
|
2014
|
0.98
|
|
68
|
Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
|
Proc Natl Acad Sci U S A
|
2013
|
0.97
|
|
69
|
Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
|
Cancer Res
|
2005
|
0.97
|
|
70
|
The egress of herpesviruses from cells: the unanswered questions.
|
J Virol
|
2006
|
0.97
|
|
71
|
ReVOLT: radiation-enhanced viral oncolytic therapy.
|
Int J Radiat Oncol Biol Phys
|
2006
|
0.94
|
|
72
|
The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection.
|
J Virol
|
2013
|
0.94
|
|
73
|
Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinase.
|
J Virol
|
2008
|
0.93
|
|
74
|
Herpes simplex virus 1 mutant in which the ICP0 HUL-1 E3 ubiquitin ligase site is disrupted stabilizes cdc34 but degrades D-type cyclins and exhibits diminished neurotoxicity.
|
J Virol
|
2003
|
0.93
|
|
75
|
The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes.
|
Proc Natl Acad Sci U S A
|
2009
|
0.92
|
|
76
|
Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.
|
J Virol
|
2010
|
0.92
|
|
77
|
Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
|
J Virol
|
2010
|
0.92
|
|
78
|
US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis.
|
Proc Natl Acad Sci U S A
|
2011
|
0.92
|
|
79
|
Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
|
Int J Radiat Biol
|
2009
|
0.91
|
|
80
|
HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed.
|
Proc Natl Acad Sci U S A
|
2013
|
0.91
|
|
81
|
The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.
|
J Virol
|
2013
|
0.91
|
|
82
|
Mapping of key functions of the herpes simplex virus 1 U(S)3 protein kinase: the U(S)3 protein can form functional heteromultimeric structures derived from overlapping truncated polypeptides.
|
J Virol
|
2006
|
0.90
|
|
83
|
Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA.
|
J Virol
|
2006
|
0.90
|
|
84
|
During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins.
|
Proc Natl Acad Sci U S A
|
2009
|
0.90
|
|
85
|
State and role of SRC family kinases in replication of herpes simplex virus 1.
|
J Virol
|
2006
|
0.89
|
|
86
|
In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.
|
J Virol
|
2007
|
0.88
|
|
87
|
Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature.
|
J Virol
|
2007
|
0.88
|
|
88
|
The interaction of herpes simplex virus 1 regulatory protein ICP22 with the cdc25C phosphatase is enabled in vitro by viral protein kinases US3 and UL13.
|
J Virol
|
2008
|
0.87
|
|
89
|
Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
|
Cancer Res
|
2007
|
0.87
|
|
90
|
RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.
|
Proc Natl Acad Sci U S A
|
2014
|
0.86
|
|
91
|
Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal.
|
J Virol
|
2010
|
0.85
|
|
92
|
Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis.
|
Virology
|
2003
|
0.85
|
|
93
|
Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow.
|
Proc Natl Acad Sci U S A
|
2007
|
0.85
|
|
94
|
Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication.
|
J Virol
|
2008
|
0.83
|
|
95
|
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
|
J Virol
|
2013
|
0.83
|
|
96
|
Bcl-2 blocks accretion or depletion of stored calcium but has no effect on the redistribution of IP3 receptor I mediated by glycoprotein E of herpes simplex virus 1.
|
J Virol
|
2007
|
0.82
|
|
97
|
Truncated forms of glycoprotein D of herpes simplex virus 1 capable of blocking apoptosis and of low-efficiency entry into cells form a heterodimer dependent on the presence of a cysteine located in the shared transmembrane domains.
|
J Virol
|
2002
|
0.82
|
|
98
|
The role of the CoREST/REST repressor complex in herpes simplex virus 1 productive infection and in latency.
|
Viruses
|
2013
|
0.81
|
|
99
|
Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression.
|
J Virol
|
2012
|
0.81
|
|
100
|
The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs.
|
J Virol
|
2013
|
0.81
|
|
101
|
Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
|
J Virol
|
2003
|
0.79
|
|
102
|
Sustained inhibition of experimental neointimal hyperplasia with a genetically modified herpes simplex virus.
|
J Vasc Surg
|
2003
|
0.78
|
|
103
|
Modulation of vascular remodeling induced by a brief intraluminal exposure to the recombinant R7020 strain of Herpes simplex-1.
|
J Vasc Surg
|
2005
|
0.78
|
|
104
|
The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase.
|
J Virol
|
2014
|
0.78
|
|
105
|
The novel HSV-1 US5-1 RNA is transcribed off a domain encoding US5, US4, US3, US2 and alpha22.
|
Virol J
|
2010
|
0.77
|
|
106
|
Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression.
|
Proc Natl Acad Sci U S A
|
2012
|
0.75
|
|
107
|
Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA.
|
Virol J
|
2007
|
0.75
|