Published in J Neurochem on August 06, 2007
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J (2012) 1.70
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J Neurosci (2010) 1.57
Histone deacetylase 6 interacts with the microtubule-associated protein tau. J Neurochem (2008) 1.38
GSK3beta is a negative regulator of platelet function and thrombosis. Blood (2008) 1.27
A dynamic view of domain-motif interactions. PLoS Comput Biol (2012) 0.98
Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding. J Biol Chem (2010) 0.96
Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau. PLoS One (2011) 0.92
Pin1, a new player in the fate of HIF-1α degradation: an hypothetical mechanism inside vascular damage as Alzheimer's disease risk factor. Front Cell Neurosci (2014) 0.88
Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics. J Biol Chem (2014) 0.77
Threonine(175), a novel pathological phosphorylation site on tau protein linked to multiple tauopathies. Acta Neuropathol Commun (2017) 0.75
Function and regulation of tau conformations in the development and treatment of traumatic brain injury and neurodegeneration. Cell Biosci (2016) 0.75
AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo. Sci Rep (2016) 0.75
Alpha 1-Antichymotrypsin, an Inflammatory Protein Overexpressed in the Brains of Patients with Alzheimer's Disease, Induces Tau Hyperphosphorylation through c-Jun N-Terminal Kinase Activation. Int J Alzheimers Dis (2013) 0.75
Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease. eNeuro (2017) 0.75
Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease. J Pediatr Gastroenterol Nutr (2007) 3.20
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature (2006) 2.61
miR-146b is highly expressed in adult papillary thyroid carcinomas with high risk features including extrathyroidal invasion and the BRAF(V600E) mutation. Thyroid (2010) 2.30
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc Natl Acad Sci U S A (2002) 2.28
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci U S A (2008) 1.97
Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease. Cancer Biol Ther (2011) 1.72
Get With the Guidelines-Stroke performance indicators: surveillance of stroke care in the Taiwan Stroke Registry: Get With the Guidelines-Stroke in Taiwan. Circulation (2010) 1.64
MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. Carcinogenesis (2012) 1.58
Hexamethonium reverses the lethal cardiopulmonary damages in a rat model of brainstem lesions mimicking fatal enterovirus 71 encephalitis. Crit Care Med (2013) 1.49
Urinary incontinence: an under-recognized risk factor for falls among elderly dementia patients. Neurourol Urodyn (2011) 1.48
Stroke registry in Kaohsiung Veterans General Hospital. Zhonghua Yi Xue Za Zhi (Taipei) (2002) 1.48
MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer. Exp Cell Res (2009) 1.48
Different impacts of α- and β-blockers in neurogenic hypertension produced by brainstem lesions in rat. Anesthesiology (2014) 1.45
Hypertonic saline enhances host defense to bacterial challenge by augmenting Toll-like receptors. Crit Care Med (2006) 1.40
Recurrent primary intracerebral hemorrhage: a hospital based study. Acta Neurol Taiwan (2007) 1.38
A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells. J Biol Chem (2008) 1.22
Different clinical and laboratory manifestations between dengue haemorrhagic fever and dengue fever with bleeding tendency. Trans R Soc Trop Med Hyg (2007) 1.21
Cisplatin selects for multidrug-resistant CD133+ cells in lung adenocarcinoma by activating Notch signaling. Cancer Res (2012) 1.20
Post-translational modification of Rta of Epstein-Barr virus by SUMO-1. J Biol Chem (2004) 1.14
No correlation between BRAFV600E mutation and clinicopathological features of papillary thyroid carcinomas in Taiwan. Clin Endocrinol (Oxf) (2005) 1.13
Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas. Oncogene (2002) 1.09
Loss of RUNX3 expression correlates with differentiation, nodal metastasis, and poor prognosis of gastric cancer. Ann Surg Oncol (2009) 1.08
Functional role of NF-IL6beta and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene. Nucleic Acids Res (2006) 1.08
Altered T helper 1 reaction but not increase of virus load in patients with dengue hemorrhagic fever. FEMS Immunol Med Microbiol (2005) 1.08
Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells. Immunology (2008) 1.03
Mouse kidney progenitor cells accelerate renal regeneration and prolong survival after ischemic injury. Stem Cells (2010) 1.02
Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1). Food Chem Toxicol (2005) 1.02
MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells. Int J Mol Med (2012) 1.01
Role of the TSG101 gene in Epstein-Barr virus late gene transcription. J Virol (2006) 0.98
Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure. Circ Res (2010) 0.97
HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis. Biochim Biophys Acta (2008) 0.97
Rapid induction of orthotopic hepatocellular carcinoma in immune-competent rats by non-invasive ultrasound-guided cells implantation. BMC Gastroenterol (2010) 0.97
Adenosine modulates cardiovascular functions through activation of extracellular signal-regulated kinases 1 and 2 and endothelial nitric oxide synthase in the nucleus tractus solitarii of rats. Circulation (2008) 0.96
Mechanisms of star fruit-induced acute renal failure. Food Chem Toxicol (2008) 0.96
In situ Akt phosphorylation in the nucleus tractus solitarii is involved in central control of blood pressure and heart rate. Circulation (2004) 0.95
Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain. Biochem Biophys Res Commun (2005) 0.94
GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress. PLoS One (2012) 0.93
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer. Am J Respir Crit Care Med (2012) 0.93
Overexpression of T-LAK cell-originated protein kinase predicts poor prognosis in patients with stage I lung adenocarcinoma. Cancer Sci (2012) 0.93
Combination of CTLA-4 and TGFbeta1 gene polymorphisms associated with dengue hemorrhagic fever and virus load in a dengue-2 outbreak. Clin Immunol (2009) 0.92
The role of oxalate in star fruit neurotoxicity of five-sixths nephrectomized rats. Food Chem Toxicol (2007) 0.92
The cytoplasmic domain of human immunodeficiency virus type 1 transmembrane protein gp41 harbors lipid raft association determinants. J Virol (2010) 0.91
Acute myocardial infarction after heroin injections. Jpn Heart J (2004) 0.91
Preincisional subcutaneous infiltration of ketamine suppresses postoperative pain after circumcision surgery. Clin J Pain (2007) 0.91
GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta. Biochemistry (2006) 0.90
Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism. Br J Pharmacol (2014) 0.90
Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2 -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways. Hum Exp Toxicol (2010) 0.90
Role of diffusion-weighted imaging and proton MR spectroscopy in distinguishing between pyogenic brain abscess and necrotic brain tumor. Acta Neurol Taiwan (2004) 0.90
Glycogen synthase kinase 3 β activity is required for hBora/Aurora A-mediated mitotic entry. Cell Cycle (2013) 0.89
A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors. FEBS Lett (2004) 0.89
Thermal injury-induced priming effect of neutrophil is TNF-alpha and P38 dependent. Shock (2006) 0.89
Association of cognitive impairment, depressive symptoms and sarcopenia among healthy older men in the veterans retirement community in southern Taiwan: a cross-sectional study. Geriatr Gerontol Int (2014) 0.88
The blood-brain barrier in the cerebrum is the initial site for the Japanese encephalitis virus entering the central nervous system. J Neurovirol (2008) 0.88
Efficacy and safety of levetiracetam as adjunctive therapy in adult patients with uncontrolled partial epilepsy: the Asia SKATE II Study. Epilepsy Behav (2010) 0.88
Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression. Int J Cancer (2014) 0.87
WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase. Cell Cycle (2015) 0.87
Caffeine intake improves fructose-induced hypertension and insulin resistance by enhancing central insulin signaling. Hypertension (2013) 0.86
Alpha1-antitrypsin precursor in gastric juice is a novel biomarker for gastric cancer and ulcer. Clin Cancer Res (2007) 0.86
Double-balloon cervical ripening catheter works well as an intrauterine balloon tamponade in post-abortion massive hemorrhage. Taiwan J Obstet Gynecol (2012) 0.86
Moderate dietary restriction reduces p53-mediated neurovascular damage and microglia activation after hypoxic ischemia in neonatal brain. Stroke (2011) 0.86
CEBPD reverses RB/E2F1-mediated gene repression and participates in HMDB-induced apoptosis of cancer cells. Clin Cancer Res (2010) 0.86
Selective occurrence of ras mutations in benign and malignant thyroid follicular neoplasms in Taiwan. Thyroid (2004) 0.85
SUMO regulates the cytoplasmonuclear transport of its target protein Daxx. J Cell Biochem (2006) 0.85
Increased total TAU but not amyloid-beta(42) in cerebrospinal fluid correlates with short-term memory impairment in Alzheimer's disease. J Alzheimers Dis (2009) 0.85
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma. Mol Cell Proteomics (2013) 0.84
The clinicopathological significance of p53 and p21 expression in squamous cell carcinoma of hypopharyngeal cancer. Cancer Lett (2003) 0.84
Bone marrow-derived mesenchymal stem cells enhanced diabetic wound healing through recruitment of tissue regeneration in a rat model of streptozotocin-induced diabetes. Plast Reconstr Surg (2011) 0.84
Synthesis and pharmacological exploitation of clioquinol-derived copper-binding apoptosis inducers triggering reactive oxygen species generation and MAPK pathway activation. Bioorg Med Chem (2009) 0.84
Platelet glycoprotein Ia C807T, Ib C3550T, and IIIa Pl(A1/A2) polymorphisms and ischemic stroke in young Taiwanese. J Neurol Sci (2004) 0.84
Effect of point mutations in the N terminus of the lentivirus lytic peptide-1 sequence of human immunodeficiency virus type 1 transmembrane protein gp41 on Env stability. J Biol Chem (2002) 0.84
Osteopontin expression is an independent adverse prognostic factor in resectable gastrointestinal stromal tumor and its interaction with CD44 promotes tumor proliferation. Ann Surg Oncol (2010) 0.84
Sonoporation-mediated gene transfer into adult rat dorsal root ganglion cells. J Biomed Sci (2010) 0.84
Sumoylation of Rta of Epstein-Barr virus is preferentially enhanced by PIASxbeta. Virus Res (2006) 0.84
Polymorphisms of death pathway genes FAS and FASL and risk of premalignant gastric lesions. Anticancer Res (2008) 0.83
Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells. Cancer Sci (2010) 0.83
Spontaneous spinal epidural hematoma: a case report and review of the literatures. Acta Neurol Taiwan (2012) 0.83
Differential effects of quercetin, a natural polyphenolic flavonoid, on L-type calcium current in pituitary tumor (GH3) cells and neuronal NG108-15 cells. J Cell Physiol (2003) 0.83
6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. J Agric Food Chem (2010) 0.82
Cytokine genetic polymorphisms and susceptibility to Kawasaki disease in Taiwanese children. Circ J (2010) 0.82
Intrathecal spinal progenitor cell transplantation for the treatment of neuropathic pain. Cell Transplant (2002) 0.82
Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma. Oncol Rep (2009) 0.82
Pin1 acts as a negative regulator of the G2/M transition by interacting with the Aurora-A-Bora complex. J Cell Sci (2013) 0.82
Adipose-Derived Stem Cells Accelerate Diabetic Wound Healing Through the Induction of Autocrine and Paracrine Effects. Cell Transplant (2015) 0.81
Carboxyl-terminal modulator protein positively regulates Akt phosphorylation and acts as an oncogenic driver in breast cancer. Cancer Res (2013) 0.81
Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET/PTC3, and ELKS-RET) in sporadic papillary thyroid carcinomas in Taiwan Chinese. Thyroid (2005) 0.81
Clinical implication and mitotic effect of CD44 cleavage in relation to osteopontin/CD44 interaction and dysregulated cell cycle protein in gastrointestinal stromal tumor. Ann Surg Oncol (2010) 0.81
Deregulated p21(WAF1) overexpression impacts survival of surgically resected esophageal squamous cell carcinoma patients. Ann Thorac Surg (2005) 0.81
Posterior reversible encephalopathy syndrome: magnetic resonance imaging and diffusion-weighted imaging in 12 cases. Kaohsiung J Med Sci (2004) 0.81
Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms. Food Chem Toxicol (2007) 0.81
Central hypotensive effects of neuropeptide Y are modulated by endothelial nitric oxide synthase after activation by ribosomal protein S6 kinase. Br J Pharmacol (2012) 0.81
Short report: detection of Japanese encephalitis virus in mouse peripheral blood mononuclear cells using an in situ reverse transcriptase-polymerase chain reaction. Am J Trop Med Hyg (2003) 0.81
Effect of gossypol on intracellular Ca2+ regulation in human hepatoma cells. Chin J Physiol (2003) 0.81
Increase of zinc finger protein 179 in response to CCAAT/enhancer binding protein delta conferring an antiapoptotic effect in astrocytes of Alzheimer's disease. Mol Neurobiol (2014) 0.81
Central nicotinic acetylcholine receptor involved in Ca(2+) -calmodulin-endothelial nitric oxide synthase pathway modulated hypotensive effects. Br J Pharmacol (2011) 0.80
Familial hyperhomocysteinemia-related cerebral venous sinus thrombosis and pulmonary embolism: a case report. Acta Neurol Taiwan (2007) 0.80
SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization. Life Sci (2005) 0.80