Advances in SELEX and application of aptamers in the central nervous system.

PubWeight™: 0.89‹?›

🔗 View Article (PMID 17681489)

Published in Biomol Eng on July 05, 2007

Authors

Yan Yang1, Dongliang Yang, Hermann J Schluesener, Zhiren Zhang

Author Affiliations

1: Experimental Medical Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Articles by these authors

Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo. Phytother Res (2011) 2.11

Cyclooxygenases and central nervous system inflammation: conceptual neglect of cyclooxygenase 1. Arch Neurol (2003) 2.05

Role of Toll-like receptor 2 in the immune response against hepadnaviral infection. J Hepatol (2012) 1.62

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells. Hepatology (2009) 1.59

Experimental strategies to promote spinal cord regeneration--an integrative perspective. Prog Neurobiol (2006) 1.51

AUY954, a selective S1P(1) modulator, prevents experimental autoimmune neuritis. J Neuroimmunol (2009) 1.50

Role of exosomes in immune regulation. J Cell Mol Med (2006) 1.29

Acute but not chronic stimulation of glial cells in rat spinal cord by systemic injection of lipopolysaccharide is associated with hyperalgesia. Acta Neuropathol (2006) 1.22

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific. Immunology (2009) 1.21

Dexamethasone attenuates early expression of three molecules associated with microglia/macrophages activation following rat traumatic brain injury. Acta Neuropathol (2007) 1.19

Spinal cord injury-induced immune depression syndrome (SCI-IDS). Eur J Neurosci (2007) 1.18

Angiogenic proteins in brains of patients who died with cerebral malaria. J Neuroimmunol (2003) 1.15

The amino Acid residues at positions 120 to 123 are crucial for the antigenicity of hepatitis B surface antigen. J Clin Microbiol (2007) 1.12

CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury. Acta Neuropathol (2002) 1.12

Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J Immunol (2009) 1.11

Guangxi's rural health insurance scheme: evidence from an ethnic minority region in China. Rural Remote Health (2013) 1.10

Prolonged lesional expression of RhoA and RhoB following spinal cord injury. J Comp Neurol (2005) 1.07

FTY720 ameliorates experimental autoimmune neuritis by inhibition of lymphocyte and monocyte infiltration into peripheral nerves. Exp Neurol (2008) 1.06

Spinal cord injury induces early and persistent lesional P2X4 receptor expression. J Neuroimmunol (2005) 1.04

FTY720: a most promising immunosuppressant modulating immune cell functions. Mini Rev Med Chem (2007) 1.03

Persistent accumulation of cyclooxygenase-1-expressing microglial cells and macrophages and transient upregulation by endothelium in human brain injury. J Neurosurg (2002) 1.01

DNA immunization with fusion of CTLA-4 to hepatitis B virus (HBV) core protein enhanced Th2 type responses and cleared HBV with an accelerated kinetic. PLoS One (2011) 1.01

The allograft inflammatory factor-1 family of proteins. FEBS Lett (2002) 1.01

Nanosilver: application and novel aspects of toxicology. Arch Toxicol (2013) 1.01

Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg) determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance. J Virol (2012) 0.99

Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways. Cell Microbiol (2009) 0.98

Infiltrating CD14+ monocytes and expression of CD14 by activated parenchymal microglia/macrophages contribute to the pool of CD14+ cells in ischemic brain lesions. J Neuroimmunol (2002) 0.98

Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brains. J Neuroimmunol (2011) 0.97

Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication. J Gen Virol (2009) 0.97

Oxidative burst of circulating neutrophils following traumatic brain injury in human. PLoS One (2013) 0.95

Spinal cord injury-induced lesional expression of the repulsive guidance molecule (RGM). Eur J Neurosci (2005) 0.95

Ultrasensitive detection of protein using an aptamer-based exonuclease protection assay. Anal Chem (2004) 0.95

Central nervous system injury-induced repulsive guidance molecule expression in the adult human brain. Arch Neurol (2005) 0.93

An unenumerative DNA computing model for vertex coloring problem. IEEE Trans Nanobioscience (2011) 0.93

Mutant hepatitis B virus surface antigens (HBsAg) are immunogenic but may have a changed specificity. Virology (2004) 0.92

Aberrant neuronal and paracellular deposition of endostatin in brains of patients with Alzheimer's disease. J Neurosci (2002) 0.91

Lesional RhoA+ cell numbers are suppressed by anti-inflammatory, cyclooxygenase-inhibiting treatment following subacute spinal cord injury. Glia (2004) 0.90

siRNA binding proteins of microglial cells: PKR is an unanticipated ligand. J Cell Biochem (2006) 0.90

Inhibition of hepatitis B virus gene expression and replication by endoribonuclease-prepared siRNA. J Virol Methods (2008) 0.89

Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier. J Virol Methods (2004) 0.89

Spinal cord injury induction of lesional expression of profibrotic and angiogenic connective tissue growth factor confined to reactive astrocytes, invading fibroblasts and endothelial cells. J Neurosurg Spine (2005) 0.89

Expression of P2X4 receptor by lesional activated microglia during formalin-induced inflammatory pain. J Neuroimmunol (2005) 0.89

COX-3: just another COX or the solitary elusive target of paracetamol? Lancet (2003) 0.88

Expression and release of CD14 in astrocytic brain tumors. Acta Neuropathol (2003) 0.88

Immunolocalization of Toll-like receptors 2 and 4 as well as their endogenous ligand, heat shock protein 70, in rat traumatic brain injury. Neuroimmunomodulation (2011) 0.88

Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model. J Neuropathol Exp Neurol (2013) 0.87

FTY720 attenuates accumulation of EMAP-II+ and MHC-II+ monocytes in early lesions of rat traumatic brain injury. J Cell Mol Med (2007) 0.87

Nucleic acid aptamers in human viral disease. Arch Immunol Ther Exp (Warsz) (2004) 0.87

Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model. Expert Opin Investig Drugs (2007) 0.87

Lesional expression of RhoA and RhoB following traumatic brain injury in humans. J Neurotrauma (2004) 0.87

Expression of EMAP-II by activated monocytes/microglial cells in different regions of the rat hippocampus after trimethyltin-induced brain damage. Exp Neurol (2002) 0.87

Microglia activation in rat spinal cord by systemic injection of TLR3 and TLR7/8 agonists. J Neuroimmunol (2005) 0.86

TLR1/2 ligand-stimulated mouse liver endothelial cells secrete IL-12 and trigger CD8+ T cell immunity in vitro. J Immunol (2013) 0.86

Spinal cord injury induces lesional expression of the proinflammatory and antiangiogenic cytokine EMAP II. J Neurotrauma (2003) 0.86

Hydrogen sulfide prevents hydrogen peroxide-induced activation of epithelial sodium channel through a PTEN/PI(3,4,5)P3 dependent pathway. PLoS One (2013) 0.86

Expression of P2X4 receptor in rat C6 glioma by tumor-associated macrophages and activated microglia. J Neuroimmunol (2004) 0.86

Cloning, eukaryotic expression of human ISG20 and preliminary study on the effect of its anti-HBV. J Huazhong Univ Sci Technolog Med Sci (2008) 0.86

Expression of interleukin-16 in sciatic nerves, spinal roots and spinal cords of experimental autoimmune neuritis rats. Brain Pathol (2008) 0.86

Expression of interleukin-16 by tumor-associated macrophages/activated microglia in high-grade astrocytic brain tumors. Arch Immunol Ther Exp (Warsz) (2007) 0.85

Antiviral therapy for chronic hepatitis B in China. Med Microbiol Immunol (2014) 0.85

RNAi induces innate immunity through multiple cellular signaling pathways. PLoS One (2013) 0.85

Binding and uptake of immunostimulatory CpG oligodeoxynucleotides by human neuroblastoma cells. Oligonucleotides (2004) 0.85

Early lung cancer diagnosis by biosensors. Int J Mol Sci (2013) 0.84

Accumulation of connective tissue growth factor+ cells during the early phase of rat traumatic brain injury. Diagn Pathol (2014) 0.84

Effect of TSLC1 gene on proliferation, invasion and apoptosis of human hepatocellular carcinoma cell line HepG2. J Huazhong Univ Sci Technolog Med Sci (2007) 0.84

Lesional accumulation of P2X4 receptor+ monocytes following experimental traumatic brain injury. Exp Neurol (2005) 0.84

Lesional accumulation of CD163+ macrophages/microglia in rat traumatic brain injury. Brain Res (2012) 0.84

Cyclooxygenase-1 and -2 in brains of patients who died with sporadic Creutzfeldt-Jakob disease. J Mol Neurosci (2003) 0.84

Spinal cord injury-induced expression of the antiangiogenic endostatin/collagen XVIII in areas of vascular remodelling. J Neurosurg Spine (2007) 0.84

Effects of valproic acid, a histone deacetylase inhibitor, on improvement of locomotor function in rat spinal cord injury based on epigenetic science. Iran Biomed J (2012) 0.84

Therapeutic effects of cisplatin on rat experimental autoimmune encephalomyelitis. Arch Immunol Ther Exp (Warsz) (2006) 0.84

A fraction of stem bark extract of Entada africana suppresses lipopolysaccharide-induced inflammation in RAW 264.7 cells. J Ethnopharmacol (2013) 0.83

Global hypomethylation defines a sub-population of reactive microglia/macrophages in experimental traumatic brain injury. Neurosci Lett (2007) 0.83

Effect of focal cerebral infarctions on lesional RhoA and RhoB expression. Arch Neurol (2003) 0.83

Entada africana fraction CH₂Cl₂/MEOH 5% inhibits inducible nitric oxide synthase and pro-inflammatory cytokines gene expression induced by lipopolysaccharide in microglia. BMC Complement Altern Med (2013) 0.82

Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B. Virol J (2013) 0.82

A conserved linear B-cell epitope at the N-terminal region of woodchuck hepatitis virus core protein (WHcAg). J Virol Methods (2006) 0.82

Expression of interleukin-16 by microglial cells in inflammatory, autoimmune, and degenerative lesions of the rat brain. J Neuroimmunol (2004) 0.82

Distribution of Foxp3(+) T-regulatory cells in experimental autoimmune neuritis rats. Exp Neurol (2008) 0.82

Lesional accumulation of heme oxygenase-1+ microglia/macrophages in rat traumatic brain injury. Neuroreport (2013) 0.82

Multi-walled carbon nanotubes affect drug transport across cell membrane in rat astrocytes. Nanotechnology (2010) 0.81

Sequence-related amplified polymorphism (SRAP) marker as a new method for identification of endophytic fungi from Taxus. World J Microbiol Biotechnol (2011) 0.81

HDAC inhibitor MS-275 attenuates the inflammatory reaction in rat experimental autoimmune prostatitis. Prostate (2011) 0.81

Inhibition of woodchuck hepatitis virus gene expression in primary hepatocytes by siRNA enhances the cellular gene expression. Virology (2008) 0.81

Spinal cord injury-induced expression of the immune-regulatory chemokine interleukin-16 caused by activated microglia/macrophages and CD8+ cells. J Neurosurg Spine (2006) 0.80

Endothelial endostatin release is induced by general cell stress and modulated by the nitric oxide/cGMP pathway. FASEB J (2003) 0.80

Doxycycline attenuates peripheral inflammation in rat experimental autoimmune neuritis. Neurochem Res (2011) 0.80

Chronic hypoxia in cultured human podocytes inhibits BKCa channels by upregulating its β4-subunit. Biochem Biophys Res Commun (2012) 0.80

Glia activation induced by peripheral administration of aluminum oxide nanoparticles in rat brains. Nanomedicine (2009) 0.80

A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes. PLoS One (2010) 0.80

COX-3 the enzyme and the concept: steps towards highly specialized pathways and precision therapeutics? Prostaglandins Leukot Essent Fatty Acids (2003) 0.80

Molecular characterization of woodchuck type I interferons and their expression by woodchuck peripheral blood lymphocytes. Cytokine (2007) 0.80

Dexamethasone suppresses infiltration of RhoA+ cells into early lesions of rat traumatic brain injury. Acta Neuropathol (2007) 0.79