Published in Mech Dev on November 01, 1991
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions. Genome Biol (2009) 5.23
Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation. PLoS Biol (2009) 2.70
Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients. Development (1999) 2.50
Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc Natl Acad Sci U S A (1992) 2.37
Dynamical analysis of regulatory interactions in the gap gene system of Drosophila melanogaster. Genetics (2004) 2.30
Reverse engineering the gap gene network of Drosophila melanogaster. PLoS Comput Biol (2006) 2.06
Canalization of gene expression and domain shifts in the Drosophila blastoderm by dynamical attractors. PLoS Comput Biol (2009) 1.99
A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling. EMBO J (2007) 1.69
Known maternal gradients are not sufficient for the establishment of gap domains in Drosophila melanogaster. Mech Dev (2006) 1.57
The gap gene network. Cell Mol Life Sci (2010) 1.51
In and out of Torso RTK signalling. EMBO J (2003) 1.49
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. Development (2011) 1.34
Gene circuit analysis of the terminal gap gene huckebein. PLoS Comput Biol (2009) 1.28
Number, identity, and sequence of the Drosophila head segments as revealed by neural elements and their deletion patterns in mutants. Proc Natl Acad Sci U S A (1994) 1.10
Inferring Drosophila gap gene regulatory network: a parameter sensitivity and perturbation analysis. BMC Syst Biol (2009) 1.08
The tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryo. Mol Cell Biol (2006) 1.02
Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction. Mol Cell Biol (1993) 0.99
Heads and tails: evolution of antero-posterior patterning in insects. Biochim Biophys Acta (2008) 0.97
Lack of tailless leads to an increase in expression variability in Drosophila embryos. Dev Biol (2013) 0.94
Dynamics of maternal morphogen gradients in Drosophila. Curr Opin Genet Dev (2008) 0.93
Capicua integrates input from two maternal systems in Drosophila terminal patterning. EMBO J (2004) 0.93
HLH54F is required for the specification and migration of longitudinal gut muscle founders from the caudal mesoderm of Drosophila. Development (2010) 0.89
RTK signaling modulates the Dorsal gradient. Development (2012) 0.87
Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew. Genetics (2000) 0.87
Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling. Genetics (2003) 0.87
Identification of autosomal regions involved in Drosophila Raf function. Genetics (2000) 0.87
Coordinating cell fate and morphogenesis in Drosophila renal tubules. Philos Trans R Soc Lond B Biol Sci (2000) 0.83
Genetic regulation of patterned tubular branching in Drosophila. Proc Natl Acad Sci U S A (2006) 0.83
Analysis of gap gene regulation in a 3D organism-scale model of the Drosophila melanogaster embryo. PLoS One (2011) 0.83
Receptor tyrosine kinases in Drosophila development. Cold Spring Harb Perspect Biol (2013) 0.83
Quantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abdita. Elife (2015) 0.82
Sequence-based model of gap gene regulatory network. BMC Genomics (2014) 0.81
A functional antagonism between the pgc germline repressor and torso in the development of somatic cells. EMBO Rep (2009) 0.80
Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster. BMC Syst Biol (2012) 0.80
Huckebein-mediated autoregulation of Glide/Gcm triggers glia specification. EMBO J (2005) 0.80
Making models match measurements: model optimization for morphogen patterning networks. Semin Cell Dev Biol (2014) 0.75
Fluorescently labeled inhibitors detect localized serine protease activities in Drosophila melanogaster pole cells, embryos, and ovarian egg chambers. Histochem Cell Biol (2004) 0.75
The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell (1989) 3.95
The fork head domain: a novel DNA binding motif of eukaryotic transcription factors? Cell (1990) 3.11
Control of transcription by Krüppel through interactions with TFIIB and TFIIE beta. Nature (1995) 2.96
Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation. Cell (1987) 2.88
From gradients to stripes in Drosophila embryogenesis: filling in the gaps. Trends Genet (1996) 2.72
Production of phenocopies by Krüppel antisense RNA injection into Drosophila embryos. Nature (1985) 2.62
Distal-less encodes a homoeodomain protein required for limb development in Drosophila. Nature (1989) 2.38
Activation of posterior gap gene expression in the Drosophila blastoderm. Nature (1995) 2.30
Role of Drosophila alpha-adaptin in presynaptic vesicle recycling. Cell (1997) 2.25
Molecular genetics of Krüppel, a gene required for segmentation of the Drosophila embryo. Nature (1985) 2.25
RNA binding and translational suppression by bicoid. Nature (1996) 2.08
Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. EMBO J (1998) 1.97
Concentration-dependent transcriptional activation or repression by Krüppel from a single binding site. Nature (1991) 1.90
Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics (1996) 1.89
Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryo. Nature (1989) 1.80
Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps. Nature (1988) 1.77
A Drosophila homologue of human Sp1 is a head-specific segmentation gene. Nature (1993) 1.75
Differential regulation of the two transcripts from the Drosophila gap segmentation gene hunchback. EMBO J (1988) 1.75
Spatial and temporal patterns of Krüppel gene expression in early Drosophila embryos. Nature (1985) 1.73
VASA mediates translation through interaction with a Drosophila yIF2 homolog. Mol Cell (2000) 1.72
cis-acting control elements for Krüppel expression in the Drosophila embryo. EMBO J (1990) 1.70
Pole region-dependent repression of the Drosophila gap gene Krüppel by maternal gene products. Cell (1987) 1.70
Three hormone receptor-like Drosophila genes encode an identical DNA-binding finger. EMBO J (1989) 1.69
Two gap genes mediate maternal terminal pattern information in Drosophila. Science (1990) 1.68
Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the Drosophila embryo. Cell (1990) 1.67
Competition for overlapping sites in the regulatory region of the Drosophila gene Krüppel. Science (1992) 1.66
From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Genome Res (2001) 1.64
The anterior determinant bicoid of Drosophila is a derived Hox class 3 gene. Proc Natl Acad Sci U S A (1999) 1.62
Spatial control of the gap gene knirps in the Drosophila embryo by posterior morphogen system. Science (1992) 1.59
Dimerization and the control of transcription by Krüppel. Nature (1993) 1.56
Developmentally regulated Drosophila gene family encoding the fork head domain. Proc Natl Acad Sci U S A (1992) 1.54
Gene expression mediated by cis-acting sequences of the Krüppel gene in response to the Drosophila morphogens bicoid and hunchback. EMBO J (1991) 1.53
Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene. Nature (1989) 1.51
Loss of gene function through rapid mitotic cycles in the Drosophila embryo. Nature (1992) 1.50
Epidermal egr-like zinc finger protein of Drosophila participates in myotube guidance. EMBO J (1996) 1.34
The gooseberry-zipper region of Drosophila: five genes encode different spatially restricted transcripts in the embryo. EMBO J (1987) 1.31
Making stripes in the Drosophila embryo. Trends Genet (1990) 1.29
Drosophila segment borders result from unilateral repression of hedgehog activity by wingless signaling. Mol Cell (2000) 1.27
Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development. Genes Dev (1997) 1.26
Specific muscle identities are regulated by Krüppel during Drosophila embryogenesis. Development (1997) 1.25
Lack of Drosophila cytoskeletal tropomyosin affects head morphogenesis and the accumulation of oskar mRNA required for germ cell formation. EMBO J (1996) 1.23
Sequence interval within the PEST motif of Bicoid is important for translational repression of caudal mRNA in the anterior region of the Drosophila embryo. EMBO J (1999) 1.20
Sp1/egr-like zinc-finger protein required for endoderm specification and germ-layer formation in Drosophila. Nature (1994) 1.18
Identical transacting factor requirement for knirps and knirps-related Gene expression in the anterior but not in the posterior region of the Drosophila embryo. Mech Dev (1994) 1.17
Disruption of a putative Cys-zinc interaction eliminates the biological activity of the Krüppel finger protein. Nature (1988) 1.17
SelD homolog from Drosophila lacking selenide-dependent monoselenophosphate synthetase activity. J Mol Biol (1997) 1.16
Trans- and cis-acting requirements for blastodermal expression of the head gap gene buttonhead. Mech Dev (1995) 1.16
A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system. Curr Biol (1998) 1.12
Target sequences for hunchback in a control region conferring Ultrabithorax expression boundaries. Development (1991) 1.12
Common and diverged functions of the Drosophila gene pair D-Sp1 and buttonhead. Mech Dev (1999) 1.12
Number, identity, and sequence of the Drosophila head segments as revealed by neural elements and their deletion patterns in mutants. Proc Natl Acad Sci U S A (1994) 1.10
hairy stripe 7 element mediates activation and repression in response to different domains and levels of Krüppel in the Drosophila embryo. Mech Dev (1999) 1.08
Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence. Proc Natl Acad Sci U S A (1986) 1.08
A cascade of transcriptional control leading to axis determination in Drosophila. J Cell Physiol (1997) 1.08
Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila. Proc Natl Acad Sci U S A (1994) 1.08
Mechanism and Bicoid-dependent control of hairy stripe 7 expression in the posterior region of the Drosophila embryo. EMBO J (1997) 1.06
Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Krüppel gene expression in the Drosophila blastoderm embryo. Development (1989) 1.06
Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development (1994) 1.06
Transcriptional regulation and spatial patterning in Drosophila. Curr Opin Genet Dev (1993) 1.06
Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo. EMBO J (1988) 1.04
Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Krüppel gene activity. Neuron (1992) 1.04
Genetic analysis of the larval optic nerve projection in Drosophila. Development (1997) 1.03
Gene regulation in the Drosophila embryo. Philos Trans R Soc Lond B Biol Sci (1996) 1.03
Epidermal muscle attachment site-specific target gene expression and interference with myotube guidance in response to ectopic stripe expression in the developing Drosophila epidermis. Proc Natl Acad Sci U S A (1997) 1.01
buttonhead does not contribute to a combinatorial code proposed for Drosophila head development. Development (1997) 1.01
Visualization of proteins after isoelectric focusing during two-dimensional gel electrophoresis. Anal Biochem (1979) 1.01
Receptor tyrosine kinase signaling regulates different modes of Groucho-dependent control of Dorsal. Curr Biol (2000) 1.00
Redundant functions of the genes knirps and knirps-related for the establishment of anterior Drosophila head structures. Proc Natl Acad Sci U S A (1994) 0.99
The class 2 selenophosphate synthetase gene of Drosophila contains a functional mammalian-type SECIS. EMBO Rep (2000) 0.98
Drosophila goosecoid participates in neural development but not in body axis formation. EMBO J (1996) 0.98
buttonhead and D-Sp1: a novel Drosophila gene pair. Mech Dev (1996) 0.97
The Drosophila fork head domain protein crocodile is required for the establishment of head structures. EMBO J (1995) 0.96
From sequence to chromosome: the tip of the X chromosome of D. melanogaster. Science (2000) 0.96
A two-step mode of stripe formation in the Drosophila blastoderm requires interactions among primary pair rule genes. Mech Dev (1994) 0.96
Regulatory elements controlling expression of the Drosophila homeotic gene fork head. EMBO J (1990) 0.96
Molecular analysis of Krüppel, a segmentation gene of Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (1985) 0.96
The interaction of DNA with the DNA-binding domain encoded by the Drosophila gene fork head. Eur J Biochem (1994) 0.95
Drosophila mode of metamerization in the embryogenesis of the lepidopteran insect Manduca sexta. Proc Natl Acad Sci U S A (1994) 0.95
Localized protein synthesis during oogenesis of Xenopus laevis: analysis by in situ translation. Dev Biol (1982) 0.94
Mesoderm-specific B104 expression in the Drosophila embryo is mediated by internal cis-acting elements of the transposon. Chromosoma (1995) 0.94
Zipper encodes a putative integral membrane protein required for normal axon patterning during Drosophila neurogenesis. EMBO J (1988) 0.94
Cooperative action of antioxidant defense systems in Drosophila. Curr Biol (2001) 0.94
A modifier screen in the eye reveals control genes for Krüppel activity in the Drosophila embryo. Proc Natl Acad Sci U S A (1998) 0.93
Dorsal and neural expression of a tyrosine kinase-related Drosophila gene during embryonic development. Genes Dev (1987) 0.93
Invagination centers within the Drosophila stomatogastric nervous system anlage are positioned by Notch-mediated signaling which is spatially controlled through wingless. Development (1995) 0.93
Functional and conserved domains of the Drosophila transcription factor encoded by the segmentation gene knirps. Mol Cell Biol (1994) 0.93
The homeotic gene spalt (sal) evolved during Drosophila speciation. Proc Natl Acad Sci U S A (1989) 0.92
Homeodomain position 54 specifies transcriptional versus translational control by Bicoid. Mol Cell (2000) 0.92
Restricted expression and subnuclear localization of the Drosophila gene Dnop5, a member of the Nop/Sik family of the conserved rRNA processing factors. Mech Dev (2000) 0.91
huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding. Neuron (1995) 0.91
Role of gap genes in early Drosophila development. Adv Genet (1990) 0.91
Molecular cloning of microdissected lampbrush loop DNA sequences of Drosophila hydei. EMBO J (1983) 0.90
Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling. Development (2000) 0.90
Phenotypic suppression of empty spiracles is prevented by buttonhead. Nature (2000) 0.89
A comparative study of lysozyme conformation in various reverse micellar systems. Biopolymers (1986) 0.88
Krüppel, a Drosophila segmentation gene, participates in the specification of neurons and glial cells. Mech Dev (1996) 0.88
The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation. EMBO Rep (2001) 0.86
Regulation and function of the terminal gap gene huckebein in the Drosophila blastoderm. Int J Dev Biol (1996) 0.86
Genetic analysis of stomatogastric nervous system development in Drosophila using enhancer trap lines. Dev Biol (1997) 0.86