Published in Curr Med Chem on January 01, 2007
The interaction of telomeric DNA and C-myc22 G-quadruplex with 11 natural alkaloids. Nucleic Acid Ther (2012) 1.49
Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci (2014) 1.16
An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin. Evid Based Complement Alternat Med (2013) 1.06
Synthesis of protopanaxadiol derivatives and evaluation of their anticancer activities. Anticancer Drugs (2011) 0.98
Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model. PLoS One (2012) 0.87
Super Natural II--a database of natural products. Nucleic Acids Res (2014) 0.86
Phytomedicine in otorhinolaryngology and pulmonology: clinical trials with herbal remedies. Pharmaceuticals (Basel) (2012) 0.84
Antiangiogenic activity and pharmacogenomics of medicinal plants from traditional korean medicine. Evid Based Complement Alternat Med (2013) 0.82
Design, Synthesis and Cytotoxicity Evaluation of New 2-Aryl-5, 6-Dihydropyrrolo[2, 1-a]Isoquinoline Derivatives as Topoisomerase Inhibitors. Iran J Pharm Res (2014) 0.81
Tamoxifen enhances the anticancer effect of cantharidin and norcantharidin in pancreatic cancer cell lines through inhibition of the protein kinase C signaling pathway. Oncol Lett (2014) 0.80
Potential roles of longan flower and seed extracts for anti-cancer. World J Exp Med (2012) 0.78
Effects of Oplopanax horridus on human colorectal cancer cells. Anticancer Res (2010) 0.78
Modes of Action of Herbal Medicines and Plant Secondary Metabolites. Medicines (Basel) (2015) 0.76
Functional Characterisation of Anticancer Activity in the Aqueous Extract of Helicteres angustifolia L. Roots. PLoS One (2016) 0.76
Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo. Evid Based Complement Alternat Med (2013) 0.76
Asclepiasterol, a novel C21 steroidal glycoside derived from Asclepias curassavica, reverses tumor multidrug resistance by down-regulating P-glycoprotein expression. Oncotarget (2016) 0.75
Cytotoxicity, genotoxicity and mechanism of action (via gene expression analysis) of the indole alkaloid aspidospermine (antiparasitic) extracted from Aspidosperma polyneuron in HepG2 cells. Cytotechnology (2015) 0.75
Huaier restrains proliferative and invasive potential of human hepatoma SKHEP-1 cells partially through decreased Lamin B1 and elevated NOV. Sci Rep (2016) 0.75
An In silico Based Comparison of Drug Interactions in Wild and Mutant Human β-tubulin through Docking Studies. Avicenna J Med Biotechnol (2014) 0.75
The crystal structure of plant sulfite oxidase provides insights into sulfite oxidation in plants and animals. Structure (2003) 2.15
Gephyrin: where do we stand, where do we go? Trends Neurosci (2008) 2.10
Structure of the molybdopterin-bound Cnx1G domain links molybdenum and copper metabolism. Nature (2004) 1.81
Leaf herbivory and nutrients increase nectar alkaloids. Ecol Lett (2006) 1.62
Salvia (Lamiaceae) is not monophyletic: implications for the systematics, radiation, and ecological specializations of Salvia and tribe Mentheae. Am J Bot (2004) 1.56
Epizootic emergence of Usutu virus in wild and captive birds in Germany. PLoS One (2012) 1.55
Production and secretion of recombinant thaumatin in tobacco hairy root cultures. Biotechnol J (2012) 1.44
Cycads: their evolution, toxins, herbivores and insect pollinators. Naturwissenschaften (2002) 1.41
Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. J Neurosci (2003) 1.40
Determination of quinolizidine alkaloids in different Lupinus species by NACE using UV and MS detection. J Pharm Biomed Anal (2010) 1.39
Multiple colonization of Madagascar and Socotra by colubrid snakes: evidence from nuclear and mitochondrial gene phylogenies. Proc Biol Sci (2003) 1.35
Review camptothecin: current perspectives. Curr Med Chem (2006) 1.33
Epigallocatechin gallate from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans. Planta Med (2008) 1.25
Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves. Molecules (2009) 1.23
Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens. Phytomedicine (2010) 1.21
The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor. J Mol Biol (2006) 1.16
Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway. Autophagy (2013) 1.16
The tetrahydropyranopterin structure of the sulfur-free and metal-free molybdenum cofactor precursor. J Biol Chem (2004) 1.15
The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis. Mol Genet Metab (2005) 1.14
Genus Bupleurum: a review of its phytochemistry, pharmacology and modes of action. J Pharm Pharmacol (2010) 1.13
Volatile components of four Ethiopian Artemisia species extracts and their in vitro antitrypanosomal and cytotoxic activities. Phytomedicine (2009) 1.13
Deciphering the structural framework of glycine receptor anchoring by gephyrin. EMBO J (2006) 1.12
Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity. J Pharm Pharmacol (2011) 1.11
Changes in neural network homeostasis trigger neuropsychiatric symptoms. J Clin Invest (2014) 1.06
Molecular phylogeny of cycads inferred from rbcL sequences. Naturwissenschaften (2002) 1.04
Splice-specific roles of glycine receptor alpha3 in the hippocampus. Eur J Neurosci (2009) 1.02
Biochemical characterization of the high affinity binding between the glycine receptor and gephyrin. J Biol Chem (2004) 1.02
Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion. J Biol Chem (2004) 1.02
Regulation of glycine receptor diffusion properties and gephyrin interactions by protein kinase C. EMBO J (2011) 1.00
Biological activities of xanthatin from Xanthium strumarium leaves. Phytother Res (2011) 0.99
Chemical composition and antimicrobial activity of the essential oil of Rosemary. Environ Toxicol Pharmacol (2011) 0.98
Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens. Pharm Biol (2011) 0.97
Reliance on pollinators predicts defensive chemistry across tobacco species. Ecol Lett (2012) 0.96
A molecular phylogeny of the hawkmoth genus Hyles (Lepidoptera: Sphingidae, Macroglossinae). Mol Phylogenet Evol (2005) 0.96
Antioxidant activities and xanthine oxidase inhibitory effects of extracts and main polyphenolic compounds obtained from Geranium sibiricum L. J Agric Food Chem (2010) 0.95
Antiproliferative effects of crocin in HepG2 cells by telomerase inhibition and hTERT down-regulation. Asian Pac J Cancer Prev (2012) 0.95
Alkaloids induce programmed cell death in bloodstream forms of trypanosomes (Trypanosoma b. brucei). Molecules (2008) 0.95
Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines. Eur J Pharmacol (2009) 0.94
Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin. Phytomedicine (2011) 0.94
Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity. Bioresour Technol (2009) 0.93
Successional change in phosphorus stoichiometry explains the inverse relationship between herbivory and lupin density on Mount St. Helens. PLoS One (2009) 0.92
Molybdenum cofactor-deficient mice resemble the phenotype of human patients. Hum Mol Genet (2002) 0.92
Tetrahydroisoquinoline and beta-carboline alkaloids from Haloxylon articulatum (Cav.) Bunge (Chenopodiaceae). Z Naturforsch C (2003) 0.91
Spectroscopic and kinetic studies of Arabidopsis thaliana sulfite oxidase: nature of the redox-active orbital and electronic structure contributions to catalysis. J Am Chem Soc (2005) 0.91
Microwave-assisted aqueous enzymatic extraction of oil from pumpkin seeds and evaluation of its physicochemical properties, fatty acid compositions and antioxidant activities. Food Chem (2013) 0.91
Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells. Phytomedicine (2012) 0.90
A revised molecular phylogeny of the globally distributed hawkmoth genus Hyles (Lepidoptera: Sphingidae), based on mitochondrial and nuclear DNA sequences. Mol Phylogenet Evol (2009) 0.90
Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells. Phytomedicine (2013) 0.90
Comparison of microsatellite and single nucleotide polymorphism markers for the genetic analysis of a Galloway cattle population. Z Naturforsch C (2005) 0.89
Synthesis of cyclic pyranopterin monophosphate, a biosynthetic intermediate in the molybdenum cofactor pathway. J Med Chem (2013) 0.89
Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain (2010) 0.89
Radical scavenging and antioxidant activities of essential oil components--an experimental and computational investigation. Nat Prod Commun (2015) 0.89
Biodiesel production from yellow horn (Xanthoceras sorbifolia Bunge.) seed oil using ion exchange resin as heterogeneous catalyst. Bioresour Technol (2012) 0.88
Screening of some Tanzanian medicinal plants for their trypanocidal and cytotoxic activities. Phytother Res (2010) 0.88
Synergistic and additive effects of epigallocatechin gallate and digitonin on Plasmodium sporozoite survival and motility. PLoS One (2010) 0.88
The effects of nectar-nicotine on colony fitness of caged honeybees. J Chem Ecol (2006) 0.88
Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine. World J Gastroenterol (2009) 0.87
Microsatellite marker discovery using single molecule real-time circular consensus sequencing on the Pacific Biosciences RS. Biotechniques (2013) 0.87
Biosynthesis and molecular biology of the molybdenum cofactor (Moco). Met Ions Biol Syst (2002) 0.87
Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR). Br J Pharmacol (2011) 0.87
Antitrypanosomal activities of proteasome inhibitors. Antimicrob Agents Chemother (2002) 0.87
Antibacterial, antiviral, antiproliferative and apoptosis-inducing properties of Brackenridgea zanguebarica (Ochnaceae). J Pharm Pharmacol (2006) 0.87
Phylogeography and population structure of the saker falcon (Falco cherrug) and the influence of hybridization: mitochondrial and microsatellite data. Mol Ecol (2007) 0.86
Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae). J Pharm Pharmacol (2009) 0.86
Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes. Phytomedicine (2011) 0.86
Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells. Phytomedicine (2011) 0.86
Carotenoids reverse multidrug resistance in cancer cells by interfering with ABC-transporters. Phytomedicine (2012) 0.86
Ameliorative effect of aspalathin from rooibos (Aspalathus linearis) on acute oxidative stress in Caenorhabditis elegans. Phytomedicine (2012) 0.85
The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells. Phytother Res (2010) 0.85
Influence of resveratrol on oxidative stress resistance and life span in Caenorhabditis elegans. J Pharm Pharmacol (2013) 0.85
Gene transcript profiles of the TIA biosynthetic pathway in response to ethylene and copper reveal their interactive role in modulating TIA biosynthesis in Catharanthus roseus. Protoplasma (2014) 0.85
Chemical composition of the SFE-CO extracts from Cajanus cajan (L.) Huth and their antimicrobial activity in vitro and in vivo. Phytomedicine (2010) 0.84
Chemical composition and biological activity of Citrus jambhiri Lush. Food Chem (2011) 0.84
Calibration of a molecular clock in tits (Paridae)--do nucleotide substitution rates of mitochondrial genes deviate from the 2% rule? Mol Phylogenet Evol (2007) 0.84
Medicinally important secondary metabolites in recombinant microorganisms or plants: progress in alkaloid biosynthesis. Biotechnol J (2009) 0.84
Preliminary enrichment and separation of genistein and apigenin from extracts of pigeon pea roots by macroporous resins. Bioresour Technol (2010) 0.84
Immediate effects of nectar robbing by Palestine sunbirds (Nectarinia osea) on nectar alkaloid concentrations in tree tobacco (Nicotiana glauca). J Chem Ecol (2014) 0.84
Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells. Z Naturforsch C (2007) 0.84
The alkaloid emetine as a promising agent for the induction and enhancement of drug-induced apoptosis in leukemia cells. Oncol Rep (2007) 0.84
Anthocyanin-rich purple wheat prolongs the life span of Caenorhabditis elegans probably by activating the DAF-16/FOXO transcription factor. J Agric Food Chem (2013) 0.83
Anti-proliferative and pro-apoptotic effect of CPT13, a novel camptothecin analog, on human colon cancer HCT8 cell line. Chem Biol Interact (2008) 0.83
Chemical structures of 4-oxo-flavonoids in relation to inhibition of oxidized low-density lipoprotein (LDL)-induced vascular endothelial dysfunction. Int J Mol Sci (2011) 0.83
Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells. Phytomedicine (2012) 0.83
Variation of active constituents and antioxidant activity in pyrola [P. incarnata Fisch.] from different sites in Northeast China. Food Chem (2013) 0.82
Antihepatotoxic activity and chemical constituents of Buddleja asiatica Lour. Z Naturforsch C (2009) 0.82
Binding of phytoestrogens to rat uterine estrogen receptors and human sex hormone-binding globulins. Z Naturforsch C (2005) 0.82
Isolation and characterization of 13 novel polymorphic microsatellite markers for Pinus koraiensis (Pinaceae). Am J Bot (2012) 0.82
Molecular cloning and expression of ranalexin, a bioactive antimicrobial peptide from Rana catesbeiana in Escherichia coli and assessments of its biological activities. Appl Microbiol Biotechnol (2012) 0.82
Characteristics of apoptosis induction by the alkaloid emetine in human tumour cell lines. Planta Med (2007) 0.81
Determination of main taxoids in Taxus species by microwave-assisted extraction combined with LC-MS/MS analysis. J Sep Sci (2009) 0.81
Effective bioconversion of sophoricoside to genistein from Fructus sophorae using immobilized Aspergillus niger and Yeast. World J Microbiol Biotechnol (2014) 0.81