|
1
|
Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia.
|
J Clin Endocrinol Metab
|
2006
|
2.72
|
|
2
|
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis.
|
Liver Int
|
2009
|
2.27
|
|
3
|
Endocannabinoids and the regulation of their levels in health and disease.
|
Curr Opin Lipidol
|
2007
|
1.75
|
|
4
|
Attenuation of allergic contact dermatitis through the endocannabinoid system.
|
Science
|
2007
|
1.70
|
|
5
|
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats.
|
J Mol Med (Berl)
|
2007
|
1.65
|
|
6
|
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors.
|
J Pharmacol Exp Ther
|
2005
|
1.56
|
|
7
|
Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding.
|
Br J Pharmacol
|
2009
|
1.55
|
|
8
|
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.
|
Br J Pharmacol
|
2011
|
1.53
|
|
9
|
Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets.
|
Mol Cell Endocrinol
|
2008
|
1.30
|
|
10
|
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats.
|
PLoS One
|
2011
|
1.24
|
|
11
|
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels.
|
Neuropsychopharmacology
|
2008
|
1.21
|
|
12
|
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.
|
Eur J Endocrinol
|
2009
|
1.19
|
|
13
|
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
|
Nat Med
|
2012
|
1.15
|
|
14
|
Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
|
Gastroenterology
|
2005
|
1.12
|
|
15
|
The endocannabinoid system is modulated in response to spinal cord injury in rats.
|
Neurobiol Dis
|
2008
|
1.10
|
|
16
|
Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients.
|
Lipids Health Dis
|
2010
|
1.09
|
|
17
|
The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis.
|
Proc Natl Acad Sci U S A
|
2009
|
1.08
|
|
18
|
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
|
J Mol Med (Berl)
|
2007
|
1.07
|
|
19
|
Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo.
|
Biochim Biophys Acta
|
2008
|
1.06
|
|
20
|
Protective activation of the endocannabinoid system during ischemia in dopamine neurons.
|
Neurobiol Dis
|
2006
|
1.04
|
|
21
|
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.
|
FASEB J
|
2007
|
1.04
|
|
22
|
Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy.
|
Neuropharmacology
|
2012
|
1.03
|
|
23
|
Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.
|
Mol Cell Biol
|
2006
|
1.02
|
|
24
|
Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats.
|
Obesity (Silver Spring)
|
2009
|
1.02
|
|
25
|
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
|
FASEB J
|
2005
|
1.02
|
|
26
|
The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy.
|
Bone
|
2011
|
1.01
|
|
27
|
Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis.
|
J Mol Med (Berl)
|
2009
|
1.01
|
|
28
|
Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats.
|
J Neurosci
|
2012
|
1.00
|
|
29
|
Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide.
|
J Cell Mol Med
|
2011
|
0.99
|
|
30
|
Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels.
|
Biochem Pharmacol
|
2005
|
0.99
|
|
31
|
Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism.
|
PLoS One
|
2013
|
0.99
|
|
32
|
Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons.
|
Proc Natl Acad Sci U S A
|
2013
|
0.99
|
|
33
|
From endocannabinoid profiling to 'endocannabinoid therapeutics'.
|
Curr Opin Chem Biol
|
2009
|
0.99
|
|
34
|
Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide.
|
Eur J Neurosci
|
2008
|
0.98
|
|
35
|
Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes.
|
Biochim Biophys Acta
|
2007
|
0.97
|
|
36
|
Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system.
|
Eur J Neurosci
|
2006
|
0.97
|
|
37
|
Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis.
|
Atherosclerosis
|
2009
|
0.97
|
|
38
|
Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew.
|
Neuropharmacology
|
2005
|
0.97
|
|
39
|
Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase.
|
Bioorg Med Chem Lett
|
2009
|
0.94
|
|
40
|
Anti-inflammatory effect of palmitoylethanolamide on human adipocytes.
|
Obesity (Silver Spring)
|
2009
|
0.94
|
|
41
|
Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice.
|
FASEB J
|
2006
|
0.94
|
|
42
|
The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization.
|
Behav Brain Res
|
2007
|
0.93
|
|
43
|
Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins.
|
Neuropharmacology
|
2007
|
0.92
|
|
44
|
Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice.
|
J Mol Med (Berl)
|
2008
|
0.92
|
|
45
|
TRPV1-dependent and -independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception.
|
Cereb Cortex
|
2011
|
0.91
|
|
46
|
The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats.
|
Neuropharmacology
|
2008
|
0.91
|
|
47
|
Possible Anandamide and Palmitoylethanolamide involvement in human stroke.
|
Lipids Health Dis
|
2010
|
0.89
|
|
48
|
The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.
|
Pharmacol Res
|
2010
|
0.89
|
|
49
|
Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease.
|
Neurochem Int
|
2007
|
0.89
|
|
50
|
Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.
|
J Mol Med (Berl)
|
2007
|
0.88
|
|
51
|
Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans.
|
Metabolism
|
2009
|
0.87
|
|
52
|
Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia.
|
Int J Neuropsychopharmacol
|
2008
|
0.87
|
|
53
|
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin.
|
Neuropharmacology
|
2008
|
0.87
|
|
54
|
Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine.
|
Int J Neuropsychopharmacol
|
2010
|
0.87
|
|
55
|
Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent.
|
Br J Pharmacol
|
2014
|
0.86
|
|
56
|
Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.
|
Arch Dermatol Res
|
2011
|
0.86
|
|
57
|
A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up.
|
Biol Reprod
|
2009
|
0.86
|
|
58
|
The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma.
|
Endocrinology
|
2010
|
0.85
|
|
59
|
Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems.
|
Pharmacol Res
|
2010
|
0.85
|
|
60
|
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems.
|
Neurobiol Dis
|
2009
|
0.83
|
|
61
|
Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs.
|
Vet J
|
2011
|
0.83
|
|
62
|
Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study.
|
Obesity (Silver Spring)
|
2013
|
0.83
|
|
63
|
Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala.
|
Neuropsychopharmacology
|
2013
|
0.81
|
|
64
|
Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system.
|
Dev Neurobiol
|
2008
|
0.81
|
|
65
|
Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis.
|
BMC Vet Res
|
2014
|
0.81
|
|
66
|
The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties.
|
PLoS One
|
2013
|
0.79
|
|
67
|
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish.
|
Gen Comp Endocrinol
|
2009
|
0.79
|