Published in Expert Rev Proteomics on August 01, 2007
Manipulating biological agents and cells in micro-scale volumes for applications in medicine. Chem Soc Rev (2013) 1.27
Microengineering methods for cell-based microarrays and high-throughput drug-screening applications. Biofabrication (2011) 0.97
Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Res (2008) 0.83
Direct assembling methodologies for high-throughput bioscreening. Biotechnol J (2011) 0.77
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Development of an image-based screening system for inhibitors of the plastidial MEP pathway and of protein geranylgeranylation. F1000Res (2015) 0.75
A rapid microwell fluorescence immunoassay for cellular protein detection. Biol Proced Online (2008) 0.75
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell (2009) 6.89
High-throughput RNAi screening by time-lapse imaging of live human cells. Nat Methods (2006) 4.86
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Spectral imaging and its applications in live cell microscopy. FEBS Lett (2003) 3.67
Automatic identification of subcellular phenotypes on human cell arrays. Genome Res (2004) 3.25
Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe (2011) 3.05
Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nat Cell Biol (2002) 3.01
Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II. Nat Genet (2009) 2.12
Reverse transfection on cell arrays for high content screening microscopy. Nat Protoc (2007) 2.09
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. Nat Methods (2013) 2.05
A microscope-based screening platform for large-scale functional protein analysis in intact cells. FEBS Lett (2003) 2.04
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol (2012) 1.88
In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum. J Cell Sci (2008) 1.77
Coupling of ER exit to microtubules through direct interaction of COPII with dynactin. Nat Cell Biol (2004) 1.76
Secretory cargo regulates the turnover of COPII subunits at single ER exit sites. Curr Biol (2006) 1.60
Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2-YFP FRET pair. FEBS Lett (2002) 1.59
Micropilot: automation of fluorescence microscopy-based imaging for systems biology. Nat Methods (2011) 1.59
Live imaging of bidirectional traffic from the ERGIC. J Cell Sci (2005) 1.58
Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection. Mol Biol Cell (2002) 1.53
Membrane-permeant phosphoinositide derivatives as modulators of growth factor signaling and neurite outgrowth. Chem Biol (2009) 1.53
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci (2002) 1.52
Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. J Struct Biol (2009) 1.48
Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts. Mol Biol Cell (2004) 1.45
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain. Nature (2012) 1.42
Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome. PLoS One (2007) 1.42
LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system. Nucleic Acids Res (2004) 1.41
Dynamics of COPII vesicles and the Golgi apparatus in cultured Nicotiana tabacum BY-2 cells provides evidence for transient association of Golgi stacks with endoplasmic reticulum exit sites. Plant Cell (2005) 1.38
In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nat Methods (2010) 1.34
Imaging of procollagen transport reveals COPI-dependent cargo sorting during ER-to-Golgi transport in mammalian cells. J Cell Sci (2002) 1.31
Localizing the proteome. Genome Biol (2003) 1.31
Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'. Mol Biol Cell (2004) 1.26
Rab18 and Rab43 have key roles in ER-Golgi trafficking. J Cell Sci (2008) 1.26
Identification of cholesterol-regulating genes by targeted RNAi screening. Cell Metab (2009) 1.26
Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding. Mol Syst Biol (2013) 1.22
Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation. Mol Cell Proteomics (2011) 1.22
Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines. Nucleic Acids Res (2013) 1.20
Bioinformatic "Harvester": a search engine for genome-wide human, mouse, and rat protein resources. Methods Enzymol (2005) 1.19
Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka. J Leukoc Biol (2007) 1.18
A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex. Curr Biol (2006) 1.16
Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. BMC Biol (2005) 1.15
Biogenesis of tubular ER-to-Golgi transport intermediates. Mol Biol Cell (2005) 1.15
Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates. J Biomol Screen (2008) 1.11
Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells. Cell Signal (2005) 1.09
From ORFeome to biology: a functional genomics pipeline. Genome Res (2004) 1.08
Sterols regulate ER-export dynamics of secretory cargo protein ts-O45-G. EMBO J (2006) 1.08
ojoplano-mediated basal constriction is essential for optic cup morphogenesis. Development (2009) 1.07
Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking. EMBO J (2005) 1.07
The first World Cell Race. Curr Biol (2012) 1.07
In vivo selective cytoskeleton dynamics quantification in interphase cells induced by pulsed ultraviolet laser nanosurgery. Traffic (2005) 1.06
An RNAi screening platform to identify secretion machinery in mammalian cells. J Biotechnol (2007) 1.04
A systems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation. J Virol (2009) 1.04
The LIFEdb database in 2006. Nucleic Acids Res (2006) 1.04
High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. Genome Res (2004) 1.02
Differential effects of a GTP-restricted mutant of Sar1p on segregation of cargo during export from the endoplasmic reticulum. J Cell Sci (2004) 1.02
Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection. Cytometry A (2009) 1.02
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase. J Cell Sci (2008) 1.01
CDNAs for functional genomics and proteomics: the German Consortium. C R Biol (2004) 1.01
'Harvester': a fast meta search engine of human protein resources. Bioinformatics (2004) 1.01
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis. J Cell Biol (2013) 1.01
Translocation biosensors to study signal-specific nucleo-cytoplasmic transport, protease activity and protein-protein interactions. Traffic (2005) 0.96
From experimental setup to bioinformatics: an RNAi screening platform to identify host factors involved in HIV-1 replication. Biotechnol J (2010) 0.96
Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues. J Biol Chem (2005) 0.95
High-content microscopy identifies new neurite outgrowth regulators. Mol Biol Cell (2006) 0.95
Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. J Proteomics (2012) 0.94
RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function. PLoS Genet (2013) 0.94
Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle. Cancer Res (2005) 0.92
Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells. Nat Chem Biol (2010) 0.92
siRNA cell arrays for high-content screening microscopy. Biotechniques (2004) 0.90
The German cDNA network: cDNAs, functional genomics and proteomics. J Struct Funct Genomics (2003) 0.90
The subcellular localization of the mammalian proteome comes a fraction closer. Genome Biol (2006) 0.90
Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion. Traffic (2010) 0.89
Normalizing for individual cell population context in the analysis of high-content cellular screens. BMC Bioinformatics (2011) 0.89
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Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells. Thromb Haemost (2004) 0.88
High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets. Cell (2013) 0.86
DetecTiff: a novel image analysis routine for high-content screening microscopy. J Biomol Screen (2009) 0.86
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases. Genome Res (2011) 0.86
A correlative light and electron microscopy method based on laser micropatterning and etching. Methods Mol Biol (2008) 0.85
miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus. PLoS One (2012) 0.84
Integrated and correlative high-throughput and super-resolution microscopy. Histochem Cell Biol (2014) 0.84
Correlative light microscopy for high-content screening. Biotechniques (2013) 0.84
A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway. Biotechnol J (2011) 0.83
Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A. PLoS One (2012) 0.82
Live-cell assays to identify regulators of ER-to-Golgi trafficking. Traffic (2012) 0.82
Production of siRNA- and cDNA-transfected cell arrays on noncoated chambered coverglass for high-content screening microscopy in living cells. Methods Mol Biol (2007) 0.81
CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum. Traffic (2014) 0.81
Measuring secretory membrane traffic: a quantitative fluorescence microscopy approach. Methods Mol Biol (2008) 0.81