Published in Am J Physiol Endocrinol Metab on August 28, 2007
Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes (2009) 3.45
Immunofluorescent detection of two thymidine analogues (CldU and IdU) in primary tissue. J Vis Exp (2010) 1.07
Retracted Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function. Mol Endocrinol (2008) 0.99
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology (2010) 0.91
TSP-1 promotes glomerular mesangial cell proliferation and extracellular matrix secretion in Thy-1 nephritis rats. J Biomed Res (2011) 0.76
Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis. Am J Physiol Endocrinol Metab (2015) 0.76
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest (2009) 7.09
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Res (2008) 4.33
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest (2005) 3.99
IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell (2011) 2.57
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype. Cell Metab (2011) 2.47
Measurement of protein turnover rates by heavy water labeling of nonessential amino acids. Biochim Biophys Acta (2006) 2.04
Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr (2007) 1.91
AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Nat Med (2009) 1.88
Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. Diabetes (2009) 1.82
Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates. Am J Physiol Endocrinol Metab (2009) 1.70
Measurement of cell proliferation by heavy water labeling. Nat Protoc (2007) 1.67
Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples. Anal Bioanal Chem (2009) 1.52
Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc (2010) 1.51
CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy. J Infect Dis (2002) 1.46
IL-33 induces IL-13-dependent cutaneous fibrosis. J Immunol (2009) 1.42
In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia. Blood (2009) 1.40
Regional cell proliferation in microdissected human prostate specimens after heavy water labeling in vivo: correlation with prostate epithelial cells isolated from seminal fluid. Clin Cancer Res (2012) 1.39
5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice. J Pharmacol Exp Ther (2010) 1.34
Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027. J Neurosci (2012) 1.31
Measurement of human plasma proteome dynamics with (2)H(2)O and liquid chromatography tandem mass spectrometry. Anal Biochem (2011) 1.30
Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells. Mol Med (2011) 1.29
Physiologic and pharmacologic factors influencing glyceroneogenic contribution to triacylglyceride glycerol measured by mass isotopomer distribution analysis. J Biol Chem (2005) 1.27
Hepatic glucose sensing is required to preserve β cell glucose competence. J Clin Invest (2013) 1.27
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression. J Immunol (2008) 1.24
Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans. J Lipid Res (2006) 1.23
Measurement of mitochondrial DNA synthesis in vivo using a stable isotope-mass spectrometric technique. J Appl Physiol (1985) (2003) 1.20
Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions. Am J Physiol Gastrointest Liver Physiol (2007) 1.17
A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. J Natl Compr Canc Netw (2011) 1.16
Thematic review series: patient-oriented research. Recent advances in liver triacylglycerol and fatty acid metabolism using stable isotope labeling techniques. J Lipid Res (2006) 1.14
A dual sugar challenge test for lipogenic sensitivity to dietary fructose. J Clin Endocrinol Metab (2011) 1.14
Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma. Cancer Med (2013) 1.13
The effect of long term calorie restriction on in vivo hepatic proteostatis: a novel combination of dynamic and quantitative proteomics. Mol Cell Proteomics (2012) 1.06
Whole-body glycolysis measured by the deuterated-glucose disposal test correlates highly with insulin resistance in vivo. Diabetes Care (2007) 1.05
Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration. J Clin Invest (2012) 1.05
Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis. J Biol Chem (2007) 1.05
Deuterium and neutrophil kinetics. Blood (2011) 1.05
Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction. J Nutr Biochem (2009) 1.04
Isolation of peripheral blood CD4(+) T cells using RosetteSep and MACS for studies of DNA turnover by deuterium labeling. J Immunol Methods (2004) 1.04
Measurement of very low rates of cell proliferation by heavy water labeling of DNA and gas chromatography/pyrolysis/isotope ratio-mass spectrometric analysis. Nat Protoc (2007) 1.04
Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med (2013) 1.02
Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats. J Appl Physiol (1985) (2012) 1.02
Measurement of brain microglial proliferation rates in vivo in response to neuroinflammatory stimuli: application to drug discovery. J Neurosci Res (2007) 1.00
Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3-creatine dilution method. J Cachexia Sarcopenia Muscle (2013) 1.00
Bevacizumab therapy for adults with recurrent/progressive meningioma: a retrospective series. J Neurooncol (2012) 1.00
Calorie restriction does not increase short-term or long-term protein synthesis. J Gerontol A Biol Sci Med Sci (2012) 1.00
Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib. Arthritis Rheumatol (2015) 1.00
In vivo measurement of microtubule dynamics using stable isotope labeling with heavy water. Effect of taxanes. J Biol Chem (2004) 0.99
Evolution of an academic hospitalist program: clinical, educational, and financial value. Am J Med (2008) 0.97
Centrosomal PKCbetaII and pericentrin are critical for human prostate cancer growth and angiogenesis. Cancer Res (2008) 0.96
Dynamics of keratinocytes in vivo using HO labeling: a sensitive marker of epidermal proliferation state. J Invest Dermatol (2004) 0.95
Discovery of novel hippocampal neurogenic agents by using an in vivo stable isotope labeling technique. J Pharmacol Exp Ther (2006) 0.94
Do calorie restriction or alternate-day fasting regimens modulate adipose tissue physiology in a way that reduces chronic disease risk? Nutr Rev (2008) 0.92
A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes. J Lipid Res (2008) 0.92
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology (2010) 0.91
Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease. Blood (2013) 0.91
Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma. J Clin Oncol (2011) 0.89
Quantifying cholesterol synthesis in vivo using (2)H(2)O: enabling back-to-back studies in the same subject. J Lipid Res (2011) 0.89
Heavy water labeling of keratin as a non-invasive biomarker of skin turnover in vivo in rodents and humans. J Invest Dermatol (2006) 0.89
Effects of caloric restriction on cell proliferation in several tissues in mice: role of intermittent feeding. Am J Physiol Endocrinol Metab (2004) 0.88
Dose effects of modified alternate-day fasting regimens on in vivo cell proliferation and plasma insulin-like growth factor-1 in mice. J Appl Physiol (1985) (2007) 0.87
Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone. J Pharmacol Exp Ther (2010) 0.87
The effect of dietary carbohydrate on genes for fatty acid synthase and inflammatory cytokines in adipose tissues from lean and obese subjects. J Nutr Biochem (2007) 0.87
Dynamics of adipose tissue development by 2H2O labeling. Methods Mol Biol (2009) 0.86
Age-related loss of noradrenergic neurons in the brains of triple transgenic mice. Age (Dordr) (2011) 0.86
Inhibition of intestinal cholesterol absorption with ezetimibe increases components of reverse cholesterol transport in humans. Atherosclerosis (2013) 0.86
Identification of phosphorylation sites within the signaling adaptor APPL1 by mass spectrometry. J Proteome Res (2010) 0.86
The effects of physiological adaptations to calorie restriction on global cell proliferation rates. Am J Physiol Endocrinol Metab (2011) 0.86
Reverse cholesterol transport fluxes. Curr Opin Lipidol (2014) 0.85
Effect of nucleoside reverse transcriptase inhibitors on mitochondrial DNA synthesis in rats and humans. J Acquir Immune Defic Syndr (2004) 0.84
Isolation of nuclei from label-retaining cells and measurement of their turnover rates in rat colon. Am J Physiol Cell Physiol (2004) 0.83
In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes (2011) 0.83
Apolipoprotein M promotes mobilization of cellular cholesterol in vivo. Biochim Biophys Acta (2013) 0.82
Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. Breast Cancer Res Treat (2005) 0.82
Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients. J Neurooncol (2011) 0.82
Plasma plant sterols serve as poor markers of cholesterol absorption in man. J Lipid Res (2012) 0.80
Circulating protein synthesis rates reveal skeletal muscle proteome dynamics. J Clin Invest (2015) 0.80
Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom (2013) 0.80
Skin blood flow abnormalities in diabetic dermopathy. J Am Acad Dermatol (2011) 0.80
Heavy water labeling of DNA for measurement of cell proliferation and recruitment during primary murine lymph node responses against model antigens. J Immunol Methods (2008) 0.80
Measurement of mouse vascular smooth muscle and atheroma cell proliferation by 2H2O incorporation into DNA. Am J Physiol Cell Physiol (2006) 0.79
Increased lipogenesis and resistance of lipoproteins to oxidative modification in two patients with glycogen storage disease type 1a. J Pediatr (2002) 0.79
Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling. Am J Physiol Endocrinol Metab (2012) 0.79
In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1. J Lipid Res (2013) 0.79
Aligning clinical compensation with clinical productivity: design and implementation of the financial value unit (FVU) system in an academic department of internal medicine. Acad Med (2013) 0.78
Pharmacological doses of dietary curcumin increase colon epithelial cell proliferation in vivo in rats. Phytother Res (2007) 0.78
Emerging applications of kinetic biomarkers in preclinical and clinical drug development. Curr Opin Drug Discov Devel (2005) 0.78
Modified alternate-day fasting and cardioprotection: relation to adipose tissue dynamics and dietary fat intake. Metabolism (2009) 0.78
Hydrophobic amino acids in the hinge region of the 5A apolipoprotein mimetic peptide are essential for promoting cholesterol efflux by the ABCA1 transporter. J Pharmacol Exp Ther (2012) 0.78
Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice. Nutrition (2008) 0.77
Back to the basics: identifying positive youth development as the theoretical framework for a youth drug prevention program in rural Saskatchewan, Canada amidst a program evaluation. Subst Abuse Treat Prev Policy (2013) 0.77
In vivo measurement of DNA synthesis rates of colon epithelial cells in carcinogenesis. Biochem Biophys Res Commun (2005) 0.77
A low alpha-linolenic intake during early life increases adiposity in the adult guinea pig. Nutr Metab (Lond) (2010) 0.76