Published in Mol Psychiatry on August 28, 2007
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med (2008) 2.74
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease. Exp Neurol (2009) 1.61
Clarifying lysosomal storage diseases. Trends Neurosci (2011) 1.57
Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline. J Alzheimers Dis (2010) 1.24
Mitochondrial medicine for aging and neurodegenerative diseases. Neuromolecular Med (2008) 1.22
Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment. J Bioenerg Biomembr (2009) 1.05
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease. Hum Mol Genet (2012) 1.04
Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases. Biochim Biophys Acta (2009) 1.01
Ecto-F₁-ATPase: a moonlighting protein complex and an unexpected apoA-I receptor. World J Gastroenterol (2010) 0.96
Is the mitochondrial outermembrane protein VDAC1 therapeutic target for Alzheimer's disease? Biochim Biophys Acta (2012) 0.92
Accumulation of exogenous amyloid-beta peptide in hippocampal mitochondria causes their dysfunction: a protective role for melatonin. Oxid Med Cell Longev (2012) 0.91
γδ T cell receptor ligands and modes of antigen recognition. Arch Immunol Ther Exp (Warsz) (2011) 0.91
Multiple proteins with essential mitochondrial functions have glycosylated isoforms. Mitochondrion (2012) 0.86
CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease. Cell Death Differ (2014) 0.86
Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. PLoS One (2012) 0.85
Metabolic labeling of Caenorhabditis elegans primary embryonic cells with azido-sugars as a tool for glycoprotein discovery. PLoS One (2012) 0.84
Mitochondrial dysfunction: different routes to Alzheimer's disease therapy. Oxid Med Cell Longev (2014) 0.82
Amyloid beta: multiple mechanisms of toxicity and only some protective effects? Oxid Med Cell Longev (2014) 0.81
Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice. Neuroscience (2010) 0.79
Mitochondrial oxidative phosphorylation complexes exist in the sarcolemma of skeletal muscle. BMB Rep (2016) 0.78
The role of astrocyte mitochondria in differential regional susceptibility to environmental neurotoxicants: tools for understanding neurodegeneration. Toxicol Sci (2015) 0.75
Temporal Phosphoproteome Dynamics Induced by an ATP Synthase Inhibitor Citreoviridin. Mol Cell Proteomics (2015) 0.75
Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease. Oxid Med Cell Longev (2016) 0.75
Ectopic F0F 1 ATP synthase contains both nuclear and mitochondrially-encoded subunits. J Bioenerg Biomembr (2013) 0.75
Melatonin and abeta, macular degeneration and alzheimers disease: same disease, different outcomes? Med Hypothesis Discov Innov Ophthalmol (2012) 0.75
Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins. Expert Rev Proteomics (2016) 0.75
Genetic ablation of the p66(Shc) adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry (2016) 0.75
Coupling factor 6 as a novel vasoactive and proatherogenic peptide in vascular endothelial cells. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.75
Field tests for rational drug use in twelve developing countries. Lancet (1993) 5.43
Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion. EMBO J (1984) 3.94
Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature (1988) 3.60
Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res (1978) 3.51
Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system. Dev Biol (1981) 3.35
Biochemistry of the filaments of brain. Proc Natl Acad Sci U S A (1976) 3.03
The J1 glycoprotein--a novel nervous system cell adhesion molecule of the L2/HNK-1 family. Nature (1985) 2.92
Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature (1984) 2.78
Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron (2000) 2.73
L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum. Nature (1983) 2.59
Human Factor XIII from plasma and platelets. Molecular weights, subunit structures, proteolytic activation, and cross-linking of fibrinogen and fibrin. J Biol Chem (1973) 2.45
Ultrastructural localization of glial fibrillary acidic protein in mouse cerebellum by immunoperoxidase labeling. J Cell Biol (1977) 2.39
Differential inhibition of neurone-neurone, neurone-astrocyte and astrocyte-astrocyte adhesion by L1, L2 and N-CAM antibodies. Nature (1985) 2.33
Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system. J Cell Biol (1981) 2.20
Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve. J Cell Biol (1986) 2.18
Clearance and binding of two electrophoretic "fast" forms of human alpha 2-macroglobulin. J Biol Chem (1981) 2.15
Disruption of the mouse L1 gene leads to malformations of the nervous system. Nat Genet (1997) 2.14
Expression of several adhesive macromolecules (N-CAM, L1, J1, NILE, uvomorulin, laminin, fibronectin, and a heparan sulfate proteoglycan) in embryonic, adult, and denervated adult skeletal muscle. J Cell Biol (1986) 2.07
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol (1999) 1.99
Angiostatin binds ATP synthase on the surface of human endothelial cells. Proc Natl Acad Sci U S A (1999) 1.95
Axonal regrowth after spinal cord transection in adult zebrafish. J Comp Neurol (1997) 1.91
Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1 leads to 3 N-acetylglucosamine linkages. Proc Natl Acad Sci U S A (1978) 1.87
The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase. J Cell Biol (1990) 1.87
Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction. J Cell Biol (1987) 1.85
Effector mechanisms of cytolytically activated macrophages. II. Secretion of a cytolytic factor by activated macrophages and its relationship to secreted neutral proteases. J Immunol (1980) 1.85
Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci U S A (2001) 1.83
Physical conditioning augments the fibrinolytic response to venous occlusion in healthy adults. N Engl J Med (1980) 1.81
Model of alpha 2-macroglobulin structure and function. Proc Natl Acad Sci U S A (1985) 1.79
Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM. Nature (1995) 1.78
Differentiation state-dependent surface mobilities of two forms of the neural cell adhesion molecule. Nature (1987) 1.78
Neural cell adhesion molecules influence second messenger systems. Neuron (1989) 1.76
The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions. J Cell Biol (1990) 1.74
Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons. Cell (1992) 1.68
Regulated expression of the neural cell adhesion molecule L1 by specific patterns of neural impulses. Science (1995) 1.68
Influence of range of renal function and liver disease on predictability of creatinine clearance. Clin Pharmacol Ther (1981) 1.68
The L2/HNK-1 carbohydrate of neural cell adhesion molecules is involved in cell interactions. J Cell Biol (1988) 1.67
The gene encoding L1, a neural adhesion molecule of the immunoglobulin family, is located on the X chromosome in mouse and man. Genomics (1990) 1.67
Potassium channel distribution, clustering, and function in remyelinating rat axons. J Neurosci (1998) 1.62
Control of mitochondrial ATP synthesis in the heart. Biochem J (1991) 1.60
The neural cell adhesion molecule is a receptor for rabies virus. J Virol (1998) 1.60
Career characteristics of graduates of a Medical Scientist Training Program, 1970-1990. Acad Med (1996) 1.58
Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets. J Clin Invest (1979) 1.55
Neurite outgrowth patterns in cerebellar microexplant cultures are affected by antibodies to the cell surface glycoprotein L1. J Neurosci (1986) 1.55
Oxidative dissociation of human alpha 2-macroglobulin tetramers into dysfunctional dimers. J Biol Chem (1994) 1.53
Selective expression of the 180-kD component of the neural cell adhesion molecule N-CAM during development. J Cell Biol (1985) 1.52
Expression of Thy-1, H-2, and NS-4 cell surface antigens and tetanus toxin receptors in early postnatal and adult mouse cerebellum. J Neuroimmunol (1981) 1.51
Biochemical and functional characterization of a novel neuron-glia adhesion molecule that is involved in neuronal migration. J Cell Biol (1987) 1.50
The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions. Cell Tissue Res (1987) 1.49
Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin. Biochim Biophys Acta (1982) 1.49
Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein. J Biol Chem (1977) 1.47
Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia. J Immunol (1992) 1.47
Demonstration of immunochemical identity between the nerve growth factor-inducible large external (NILE) glycoprotein and the cell adhesion molecule L1. EMBO J (1985) 1.46
NS-4 (nervous system antigen-4), a cell surface antigen of developing and adult mouse brain and sperm. Dev Biol (1975) 1.46
The subunit structure of normal and hemophilic factor VIII. J Clin Invest (1973) 1.46
Selective diminution of the binding of mannose by murine macrophages in the late stages of activation. J Biol Chem (1982) 1.45
The effect of plasmin on the subunit structure of human fibrinogen. J Biol Chem (1972) 1.44
Channel expression correlates with differentiation stage during the development of oligodendrocytes from their precursor cells in culture. Neuron (1989) 1.43
Immunochemical and biochemical characterization of a glioma-associated extracellular matrix glycoprotein. J Cell Biochem (1985) 1.42
Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture. J Cell Biol (1988) 1.42
The neural cell adhesion molecule L1 is distinct from the N-CAM related group of surface antigens BSP-2 and D2. EMBO J (1984) 1.40
The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development (2001) 1.40
Expression of the neural cell adhesion molecules L1 and N-CAM and their common carbohydrate epitope L2/HNK-1 during development and after transection of the mouse sciatic nerve. Differentiation (1985) 1.38
Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1. Mol Cell Biol (2002) 1.36
Environmental bias? Effects of housing conditions, laboratory environment and experimenter on behavioral tests. Genes Brain Behav (2006) 1.35
Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS. Neuron (1995) 1.35
Biosynthesis and membrane topography of the neural cell adhesion molecule L1. EMBO J (1985) 1.34
Fibroblasts that proliferate near denervated synaptic sites in skeletal muscle synthesize the adhesive molecules tenascin(J1), N-CAM, fibronectin, and a heparan sulfate proteoglycan. J Cell Biol (1989) 1.33
Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies. Nat Genet (1995) 1.33
alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation. Lab Invest (1994) 1.33
Synaptic strength as a function of post- versus presynaptic expression of the neural cell adhesion molecule NCAM. Neuron (2000) 1.32
Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R. J Comp Neurol (2000) 1.31
Receptors for maleylated proteins regulate secretion of neutral proteases by murine macrophages. Science (1982) 1.31
The clustering of axonal sodium channels during development of the peripheral nervous system. J Neurosci (1996) 1.31
Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve. J Cell Biol (1988) 1.31
Synaptic activity modulates the induction of bidirectional synaptic changes in adult mouse hippocampus. J Neurosci (2000) 1.30
The subunit structures of human plasma and platelet factor XIII (fibrin-stabilizing factor). J Biol Chem (1971) 1.30
Disruption of the gene for the myelin-associated glycoprotein improves axonal regrowth along myelin in C57BL/Wlds mice. Neuron (1996) 1.29
Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides. Exp Neurol (2001) 1.29
The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. Proc Natl Acad Sci U S A (1997) 1.29
Microtubule reorganization is obligatory for growth cone turning. Proc Natl Acad Sci U S A (1996) 1.29
Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan. J Biol Chem (1989) 1.29
Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site. Biochemistry (1989) 1.28
J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth. J Cell Biol (1991) 1.27
Contactin associates with Na+ channels and increases their functional expression. J Neurosci (2001) 1.27
Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity. J Neurosci (2000) 1.26
Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R. Proc Natl Acad Sci U S A (1998) 1.26
Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function. Neuron (1989) 1.25
Tenascin-R is a functional modulator of sodium channel beta subunits. J Biol Chem (1999) 1.25
The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation. J Neurosci Res (1996) 1.24
Biochemically differentiated mouse glial lines carrying a nervous system specific cell surface antigen (NS-1). Proc Natl Acad Sci U S A (1975) 1.24
Boundaries defined by adhesion molecules during development of the cerebral cortex: the J1/tenascin glycoprotein in the mouse somatosensory cortical barrel field. Dev Biol (1989) 1.24
J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion. J Cell Biol (1989) 1.24
Siglecs: a family of sialic-acid binding lectins. Glycobiology (1998) 1.22
The effect of fibrin-stabilizing factor on the subunit structure of human fibrin. J Clin Invest (1971) 1.22
Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32. J Neurosci (1997) 1.22
Immunohistological localization of the adhesion molecules L1, N-CAM, and MAG in the developing and adult optic nerve of mice. J Comp Neurol (1989) 1.21
Several extracellular domains of the neural cell adhesion molecule L1 are involved in neurite outgrowth and cell body adhesion. J Neurosci (1993) 1.21
Crucial role for the myelin-associated glycoprotein in the maintenance of axon-myelin integrity. Eur J Neurosci (1995) 1.20
Methionine sulfoxide and the oxidative regulation of plasma proteinase inhibitors. J Leukoc Biol (1988) 1.20