Published in J Neurosci Res on February 01, 2008
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell (2010) 17.87
RNA and disease. Cell (2009) 7.98
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. Mol Cancer Ther (2009) 2.50
Site identification in high-throughput RNA-protein interaction data. Bioinformatics (2012) 1.43
Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis. J Cell Biol (2009) 1.36
miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancer. Gut (2012) 1.25
Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation. RNA (2013) 1.17
The STAR RNA binding proteins GLD-1, QKI, SAM68 and SLM-2 bind bipartite RNA motifs. BMC Mol Biol (2009) 1.11
Temporal genomewide expression profiling of DSS colitis reveals novel inflammatory and angiogenesis genes similar to ulcerative colitis. Physiol Genomics (2010) 1.06
Linking white and grey matter in schizophrenia: oligodendrocyte and neuron pathology in the prefrontal cortex. Front Neuroanat (2009) 0.99
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes Dev (2013) 0.93
The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells. Mol Cell Biol (2013) 0.93
Essential function, sophisticated regulation and pathological impact of the selective RNA-binding protein QKI in CNS myelin development. Future Neurol (2008) 0.92
Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease. Adv Exp Med Biol (2014) 0.92
mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans. Cell Res (2011) 0.88
The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. Mol Biol Cell (2010) 0.87
The QKI-6 RNA binding protein localizes with the MBP mRNAs in stress granules of glial cells. PLoS One (2010) 0.86
The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination. PLoS One (2009) 0.85
Mouse forward genetics in the study of the peripheral nervous system and human peripheral neuropathy. Neurochem Res (2008) 0.85
QKI impairs self-renewal and tumorigenicity of oral cancer cells via repression of SOX2. Cancer Biol Ther (2014) 0.82
HSV-1 Cgal+ infection promotes quaking RNA binding protein production and induces nuclear-cytoplasmic shuttling of quaking I-5 isoform in human hepatoma cells. Mol Cell Proteomics (2011) 0.82
MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial-mesenchymal transition by targeting QKI-5 in esophageal squamous cell carcinoma. Mol Cancer (2016) 0.80
Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation. Nat Genet (2016) 0.78
Oligodendroglial defects during quakingviable cerebellar development. Dev Neurobiol (2015) 0.77
The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression. Sci Rep (2016) 0.76
MicroRNA-214 regulates smooth muscle cell differentiation from stem cells by targeting RNA-binding protein QKI. Oncotarget (2017) 0.75
The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs. Nucleic Acids Res (2016) 0.75
Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis. Stem Cells (2017) 0.75
MicroRNA-214 Promotes Dendritic Development by Targeting the Schizophrenia-associated Gene Quaking (Qki). J Biol Chem (2016) 0.75
RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA. Cell Cycle (2016) 0.75
Gene Expression of Quaking in Sporadic Alzheimer's Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation. J Alzheimers Dis (2016) 0.75
Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina. PLoS One (2016) 0.75
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression. Nat Commun (2016) 0.75
Sensitive and highly resolved identification of RNA-protein interaction sites in PAR-CLIP data. BMC Bioinformatics (2015) 0.75
Mechanism of mRNA-STAR domain interaction: Molecular dynamics simulations of Mammalian Quaking STAR protein. Sci Rep (2017) 0.75
Inhibition of COX2 enhances the chemosensitivity of dichloroacetate in cervical cancer cells. Oncotarget (2017) 0.75
Circular RNAs: Biogenesis, Function and Role in Human Diseases. Front Mol Biosci (2017) 0.75
Arginine methylation an emerging regulator of protein function. Mol Cell (2005) 6.49
Target RNA motif and target mRNAs of the Quaking STAR protein. Nat Struct Mol Biol (2005) 3.70
Birt-Hogg-Dubé syndrome: diagnosis and management. Lancet Oncol (2009) 3.60
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature (2011) 3.53
Genetic testing in pheochromocytoma or functional paraganglioma. J Clin Oncol (2005) 3.20
RNA-binding proteins in human genetic disease. Trends Genet (2008) 3.14
An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma. Cancer Cell (2011) 2.78
A proteomic analysis of arginine-methylated protein complexes. Mol Cell Proteomics (2003) 2.59
PHD2 mutation and congenital erythrocytosis with paraganglioma. N Engl J Med (2008) 2.56
von Hippel-Lindau disease: a clinical and scientific review. Eur J Hum Genet (2011) 2.45
Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. EMBO J (2010) 2.43
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J (2012) 2.34
The Y deletion gr/gr and susceptibility to testicular germ cell tumor. Am J Hum Genet (2005) 2.26
Tudor domains bind symmetrical dimethylated arginines. J Biol Chem (2005) 2.23
Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. Hum Mol Genet (2006) 2.23
Sam68, the KH domain-containing superSTAR. Biochim Biophys Acta (2003) 2.08
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression. J Virol (2005) 2.02
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. Mol Biol Cell (2003) 1.87
The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred. Urol Oncol (2009) 1.70
Germline BAP1 mutations predispose to renal cell carcinomas. Am J Hum Genet (2013) 1.69
Protection of p27(Kip1) mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation. Nat Neurosci (2004) 1.62
Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control. Genes Dev (2005) 1.61
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1. Cell (2011) 1.60
Defining the RGG/RG motif. Mol Cell (2013) 1.59
Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression. J Biol Chem (2005) 1.47
The formin homology 1 domain modulates the actin nucleation and bundling activity of Arabidopsis FORMIN1. Plant Cell (2005) 1.46
Treatment of von Hippel-Lindau retinal hemangioblastoma by the vascular endothelial growth factor receptor inhibitor SU5416 is more effective for associated macular edema than for hemangioblastomas. Am J Ophthalmol (2003) 1.42
Nuclear retention of MBP mRNAs in the quaking viable mice. Neuron (2002) 1.41
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation. Mol Cell Biol (2009) 1.40
Protein interfaces in signaling regulated by arginine methylation. Sci STKE (2005) 1.39
Sam68 regulates translation of target mRNAs in male germ cells, necessary for mouse spermatogenesis. J Cell Biol (2009) 1.36
The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. J Biol Chem (2004) 1.36
Inactivation of BHD in sporadic renal tumors. Cancer Res (2003) 1.36
Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development. J Biol Chem (2004) 1.35
Retinal hemangioblastoma in von Hippel-Lindau disease: a clinical and molecular study. Invest Ophthalmol Vis Sci (2002) 1.33
Arginine methylation of the human immunodeficiency virus type 1 Tat protein by PRMT6 negatively affects Tat Interactions with both cyclin T1 and the Tat transactivation region. J Virol (2007) 1.31
The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity. Cell Cycle (2005) 1.30
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations. Hum Mol Genet (2011) 1.27
Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response. PLoS Genet (2008) 1.20
The Sam68 STAR RNA-binding protein regulates mTOR alternative splicing during adipogenesis. Mol Cell (2012) 1.19
Genetic basis of congenital erythrocytosis: mutation update and online databases. Hum Mutat (2013) 1.18
Familial non-VHL clear cell (conventional) renal cell carcinoma: clinical features, segregation analysis, and mutation analysis of FLCN. Clin Cancer Res (2008) 1.17
The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation. Pharmacol Res (2009) 1.15
Novel FH mutations in families with hereditary leiomyomatosis and renal cell cancer (HLRCC) and patients with isolated type 2 papillary renal cell carcinoma. J Med Genet (2011) 1.14
JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5. Cell Rep (2012) 1.14
The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein. Mol Biol Cell (2002) 1.14
Genotype-phenotype correlation in von Hippel-Lindau families with renal lesions. Hum Mutat (2004) 1.13
A glycine-arginine domain in control of the human MRE11 DNA repair protein. Mol Cell Biol (2008) 1.13
Thrombospondin-1 is a transcriptional repression target of PRMT6. J Biol Chem (2009) 1.12
The STAR RNA binding proteins GLD-1, QKI, SAM68 and SLM-2 bind bipartite RNA motifs. BMC Mol Biol (2009) 1.11
PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA. Retrovirology (2006) 1.10
Hereditary leiomyomatosis and renal cell cancer (HLRCC): renal cancer risk, surveillance and treatment. Fam Cancer (2014) 1.09
Coexpression of erythropoietin and erythropoietin receptor in von Hippel-Lindau disease-associated renal cysts and renal cell carcinoma. Clin Cancer Res (2005) 1.09
An improved method to determine serine palmitoyltransferase activity. J Lipid Res (2009) 1.09
Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma. BMC Cancer (2010) 1.08
Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor. Nucleic Acids Res (2012) 1.07
Letter to the editor: Pregnancy and von Hippel-Lindau disease. J Neurosurg (2013) 1.07
Motor coordination defects in mice deficient for the Sam68 RNA-binding protein. Behav Brain Res (2008) 1.07
Renal cell tumour characteristics in patients with the Birt-Hogg-Dubé cancer susceptibility syndrome: a retrospective, multicentre study. Orphanet J Rare Dis (2014) 1.06
Methylation of MRE11 regulates its nuclear compartmentalization. Cell Cycle (2005) 1.06
Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression. BMC Med Genomics (2010) 1.06
Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors. Genes Chromosomes Cancer (2008) 1.05
Head and neck paragangliomas in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. J Clin Endocrinol Metab (2009) 1.04
Vitreoretinal surgery for severe retinal capillary hemangiomas in von hippel-lindau disease. Ophthalmology (2011) 1.04
Natural history of supratentorial hemangioblastomas in von Hippel-Lindau disease. Neurosurgery (2010) 1.03
QUAKING KH domain proteins as regulators of glial cell fate and myelination. RNA Biol (2005) 1.02
Characterization of the Drosophila protein arginine methyltransferases DART1 and DART4. Biochem J (2004) 1.00
Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia. Mol Cell Biol (2008) 1.00
An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization. Mol Cell Biol (2009) 0.99
Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells. Nucleic Acids Res (2011) 0.99
The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation. Cell Res (2011) 0.99
Real-time PCR to identify variola virus or other human pathogenic orthopox viruses. Clin Chem (2007) 0.98
BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest. Cell Signal (2009) 0.98
Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype. Circ Res (2013) 0.95
Arginine methylation signals mRNA export. Nat Struct Mol Biol (2004) 0.95
Depolarization-induced translocation of the RNA-binding protein Sam68 to the dendrites of hippocampal neurons. J Cell Sci (2004) 0.95
Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics (2010) 0.94
Arginine methylation of the HIV-1 nucleocapsid protein results in its diminished function. AIDS (2007) 0.94
The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells. Mol Cell Biol (2013) 0.93
Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration. Cell Signal (2007) 0.93
Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia. Haematologica (2011) 0.92
Type II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiation. J Biol Chem (2011) 0.91
Calcium-dependent deceleration of the cell cycle in muscle cells by simulated microgravity. FASEB J (2013) 0.90
Conservative management of endolymphatic sac tumors in von Hippel-Lindau disease: case report. Acta Neurochir (Wien) (2010) 0.90
Long-term Prognosis of Resected Pancreatic Neuroendocrine Tumors in von Hippel-Lindau Disease Is Favorable and Not Influenced by Small Tumors Left in Place. Ann Surg (2015) 0.90
Lectin-like Ox-LDL receptor is expressed in human INT-407 intestinal cells: involvement in the transcytosis of pancreatic bile salt-dependent lipase. Mol Biol Cell (2003) 0.90
Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells. Nat Commun (2013) 0.90
Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. Clin Cancer Res (2012) 0.90
No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome. Fam Cancer (2010) 0.89
Radiofrequency ablation of renal tumours: diagnostic accuracy of contrast-enhanced ultrasound for early detection of residual tumour. Eur Radiol (2010) 0.88
Identification of a Sam68 ribonucleoprotein complex regulated by epidermal growth factor. J Biol Chem (2009) 0.87
Targeting the RNA-binding protein Sam68 as a treatment for cancer? Future Oncol (2007) 0.87
Local recurrence after nephron-sparing surgery in von Hippel-Lindau disease. Urology (2007) 0.87
The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. Mol Biol Cell (2010) 0.87
The QKI-6 RNA binding protein localizes with the MBP mRNAs in stress granules of glial cells. PLoS One (2010) 0.86
The QKI-6 and QKI-7 RNA binding proteins block proliferation and promote Schwann cell myelination. PLoS One (2009) 0.85
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics (2013) 0.85
Endocrine pancreatic tumors in von Hippel-Lindau disease: clinical, histological, and genetic features. Pancreas (2008) 0.85
Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression. Am J Surg Pathol (2009) 0.84
The association of Sam68 with Vav1 contributes to tumorigenesis. Cell Signal (2007) 0.84