David E Gutstein

Author PubWeight™ 30.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circ Res 2004 2.11
2 Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f). FASEB J 2008 1.54
3 Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. Circ Res 2003 1.29
4 Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. FASEB J 2007 1.23
5 Proliferation of adult sertoli cells following conditional knockout of the Gap junctional protein GJA1 (connexin 43) in mice. Biol Reprod 2007 1.23
6 Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling. Development 2007 1.22
7 Gap junction communication between uterine stromal cells plays a critical role in pregnancy-associated neovascularization and embryo survival. Development 2008 1.22
8 Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol 2006 1.22
9 Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation. Proc Natl Acad Sci U S A 2005 1.21
10 Transgenic expression of a dominant negative K(ATP) channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion. FASEB J 2007 1.19
11 Connexin40 imparts conduction heterogeneity to atrial tissue. Circ Res 2008 1.06
12 Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood 2012 1.05
13 Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells. Proc Natl Acad Sci U S A 2012 0.99
14 Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube. Development 2006 0.97
15 Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy. Cell Commun Adhes 2006 0.95
16 The evaluation and management of drug effects on cardiac conduction (PR and QRS intervals) in clinical development. Am Heart J 2013 0.92
17 Contrast-enhanced MRI of right ventricular abnormalities in Cx43 mutant mouse embryos. NMR Biomed 2007 0.89
18 Lack of a clinically relevant effect of sugammadex on anti-Xa activity or activated partial thromboplastin time following pretreatment with either unfractionated or low-molecular-weight heparin in healthy subjects. Int J Clin Pharmacol Ther 2014 0.89
19 Dyskinesis in Chagasic myocardium: centerline analysis of wall motion using cardiac-gated magnetic resonance images of mice. Magn Reson Imaging 2006 0.89
20 Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. J Clin Invest 2015 0.88
21 Exercise training normalizes altered calcium-handling proteins during development of heart failure. J Appl Physiol (1985) 2002 0.88
22 MR imaging of caveolin gene-specific alterations in right ventricular wall thickness. Magn Reson Imaging 2005 0.87
23 MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans. Circ Arrhythm Electrophysiol 2012 0.86
24 Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry. Rapid Commun Mass Spectrom 2013 0.86
25 Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib. J Clin Pharmacol 2013 0.82
26 Short-term pacing in the mouse alters cardiac expression of connexin43. BMC Physiol 2008 0.82
27 Identification of binding partners for the cytoplasmic loop of connexin43: a novel interaction with β-tubulin. Cell Commun Adhes 2009 0.80
28 Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents. Am J Physiol Heart Circ Physiol 2008 0.79
29 Cardiac imaging approaches to evaluate drug-induced myocardial dysfunction. Am Heart J 2012 0.77
30 The cardiac gap junction: a potential therapeutic target in the treatment of heart disease. Mt Sinai J Med 2002 0.75
31 Pharmacokinetics of sugammadex in subjects with moderate and severe renal impairment
. Int J Clin Pharmacol Ther 2017 0.75
32 Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. J Clin Invest 2016 0.75
33 Quantifying monocyte infiltration in response to intradermal tetanus toxoid injection. Biomark Med 2012 0.75
34 Quantification of circulating D-dimer by peptide immunoaffinity enrichment and tandem mass spectrometry. Anal Chem 2012 0.75