PubRank

Ludo Van Den Bosch

Author PubWeight™ 62.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat Neurosci 2004 3.31
2 Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet 2006 3.04
3 Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nat Genet 2004 3.00
4 Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival. J Cell Biol 2008 2.91
5 Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat Genet 2004 2.86
6 ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol 2007 2.80
7 EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med 2012 2.65
8 HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease. Nat Med 2011 2.60
9 Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis. Brain 2013 1.78
10 Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration. Hum Mol Genet 2008 1.46
11 Calcium dysregulation in amyotrophic lateral sclerosis. Cell Calcium 2010 1.43
12 Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Proc Natl Acad Sci U S A 2007 1.42
13 HDAC6 at the Intersection of Neuroprotection and Neurodegeneration. Traffic 2012 1.29
14 Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. J Neurosci 2008 1.27
15 Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J Neurosci 2008 1.23
16 Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy. J Neurosci 2011 1.12
17 Prospective exploration of biochemical tissue composition via imaging mass spectrometry guided by principal component analysis. Pac Symp Biocomput 2007 1.09
18 Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish. Hum Mol Genet 2007 1.08
19 Upregulation of HSP27 in a transgenic model of ALS. J Neuropathol Exp Neurol 2002 1.05
20 GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2005 1.04
21 The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis. Neurosci Lett 2003 1.03
22 The neurobiology of amyotrophic lateral sclerosis. Eur J Neurosci 2010 1.02
23 Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death. Neurobiol Dis 2007 1.00
24 Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice. J Autoimmun 2012 1.00
25 VEGF protects motor neurons against excitotoxicity by upregulation of GluR2. Neurobiol Aging 2009 0.99
26 Skeletal muscle properties in a transgenic mouse model for amyotrophic lateral sclerosis: effects of creatine treatment. Neurobiol Dis 2003 0.98
27 Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS. Hum Mol Genet 2013 0.97
28 The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding. Neurobiol Aging 2013 0.94
29 Over-expression of Hsp27 does not influence disease in the mutant SOD1(G93A) mouse model of amyotrophic lateral sclerosis. J Neurochem 2008 0.91
30 Microglial upregulation of progranulin as a marker of motor neuron degeneration. J Neuropathol Exp Neurol 2010 0.89
31 Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism. Eur J Immunol 2012 0.86
32 Rapamycin increases survival in ALS mice lacking mature lymphocytes. Mol Neurodegener 2013 0.86
33 Mutant HSPB8 causes motor neuron-specific neurite degeneration. Hum Mol Genet 2010 0.85
34 Role of mitochondria in kainate-induced fast Ca2+ transients in cultured spinal motor neurons. Cell Calcium 2007 0.84
35 G37R SOD1 mutant alters mitochondrial complex I activity, Ca(2+) uptake and ATP production. Cell Calcium 2011 0.84
36 Prevention of intestinal obstruction reveals progressive neurodegeneration in mutant TDP-43 (A315T) mice. Mol Neurodegener 2014 0.83
37 Genetic variant in the HSPB1 promoter region impairs the HSP27 stress response. Hum Mutat 2007 0.83
38 Vascular endothelial growth factor in amyotrophic lateral sclerosis and other neurodegenerative diseases. Muscle Nerve 2006 0.83
39 Ivermectin inhibits AMPA receptor-mediated excitotoxicity in cultured motor neurons and extends the life span of a transgenic mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 2006 0.81
40 Long-lasting changes in GABA responsiveness in cultured neurons. Neurosci Lett 2004 0.81
41 Role of matrix metalloproteinase-9 in a mouse model for amyotrophic lateral sclerosis. Neuroreport 2005 0.81
42 Charcot-Marie-Tooth disease: emerging mechanisms and therapies. Int J Biochem Cell Biol 2012 0.80
43 Microglia in amyotrophic lateral sclerosis. Acta Neurol Belg 2007 0.80
44 Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors. Chem Commun (Camb) 2015 0.80
45 The role of oligodendroglial dysfunction in amyotrophic lateral sclerosis. Neurodegener Dis Manag 2014 0.79
46 Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice. Neurobiol Dis 2013 0.78
47 Neuronal overexpression of IP₃ receptor 2 is detrimental in mutant SOD1 mice. Biochem Biophys Res Commun 2012 0.78
48 Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats. Neurobiol Aging 2013 0.77
49 Polymorphisms in the GluR2 gene are not associated with amyotrophic lateral sclerosis. Neurobiol Aging 2010 0.76
50 L-β-N-oxalyl-α,β-diaminopropionic acid toxicity in motor neurons. Neuroreport 2011 0.75