Published in BMJ on December 14, 1991
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J Clin Invest (1999) 5.30
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest (1996) 3.44
Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo. J Clin Invest (2002) 1.12
Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor expression and mitogenic responses in human breast cancer cell lines. Br J Cancer (1995) 1.02
Parathyroid hormone related protein in hypercalcaemia of Hodgkin's disease. J Clin Pathol (1992) 0.97
Parathyroid hormone-related protein as a tumour marker in humoral hypercalcaemia associated with occult malignancy. Postgrad Med J (1993) 0.95
PTHrP and the PTH/PTHrP receptor are co-expressed in human breast and colon tumours. Br J Cancer (1997) 0.91
Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292. Clin Exp Metastasis (2011) 0.90
Parathyroid hormone related peptide and receptor expression in paired primary prostate cancer and bone metastases. Br J Cancer (2002) 0.83
Elevated serum parathyroid hormone related protein and 1,25-dihydroxycholecalciferol in hypercalcaemia associated with adult T-cell leukaemia-lymphoma. Postgrad Med J (1992) 0.77
Parathyroid hormone-related protein, bone metastases and hypercalcaemia of malignancy. Ann R Coll Surg Engl (1996) 0.75
Parathyroid hormone-related protein secretion is inhibited by oestradiol and stimulated by antioestrogens in KPL-3C human breast cancer cells. Br J Cancer (1997) 0.75
Implications of Hypoxia in Breast Cancer Metastasis to Bone. Int J Mol Sci (2016) 0.75
A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science (1987) 4.09
Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N Engl J Med (1990) 2.76
The hypercalcemia of cancer. Clinical implications and pathogenic mechanisms. N Engl J Med (1984) 2.33
Localization of parathyroid hormone-related protein in breast cancer metastases: increased incidence in bone compared with other sites. Cancer Res (1991) 2.26
Reduced morbidity from skeletal metastases in breast cancer patients during long-term bisphosphonate (APD) treatment. Lancet (1987) 1.90
Immunohistochemical localization of parathyroid hormone-related protein in human breast cancer. Cancer Res (1990) 1.54
Mechanism of malignant hypercalcaemia in carcinoma of the breast. Br Med J (Clin Res Ed) (1985) 1.45
Parathyroid hormone-related protein: immunohistochemical localization in cancers and in normal skin. J Bone Miner Res (1989) 1.28
Hypercalcemia of malignancy revisited. J Clin Invest (1988) 1.26
Parathyroid hormone-related protein in hypercalcaemia of malignancy. Clin Endocrinol (Oxf) (1989) 1.25
Development and validation of an immunoradiometric assay of parathyrin-related protein in unextracted plasma. Clin Chem (1991) 1.22
Increased serum levels of a parathyroid hormone-like protein in malignancy-associated hypercalcemia. Ann Intern Med (1989) 1.21
Immunological identification and distribution of parathyroid hormone-like protein polypeptides in normal and malignant tissues. Endocrinology (1991) 1.19
Circulating concentrations of parathyroid hormone-like peptide in malignancy and in hyperparathyroidism. J Bone Miner Res (1990) 0.99
Tamoxifen-induced hypercalcemia in breast cancer. Cancer (1981) 0.97
Parathyroid hormone-related protein of malignancy: immunohistochemical and biochemical studies in normocalcaemic and hypercalcaemic patients with cancer. J Clin Pathol (1991) 0.95
Properties of parathyroid hormone-related protein and its role in malignant hypercalcaemia. Q J Med (1990) 0.93
Breast cancer-associated hypercalcaemia: a reassessment of renal calcium and phosphate handling. Ann Clin Biochem (1990) 0.88
Hypercalcemia in breast cancer. Reassessment of the mechanism. Am J Med (1987) 0.86
Production of interleukin-1 alpha and a parathyroid hormone-like factor by a squamous cell carcinoma of the esophagus (EC-GI) derived from a patient with hypercalcemia. J Clin Endocrinol Metab (1988) 0.82
Hypercalcaemia and breast cancer--an increased humoral component in patients with liver metastases. Eur J Surg Oncol (1988) 0.81
Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States. N Engl J Med (1980) 9.34
A radioimmunoassay for rat plasma ACTH. Endocrinology (1971) 3.35
Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis. Oncogene (1987) 2.67
Altered properties of deoxyribonucleic acid nucleotidyltransferase after infection of mammalian cells with herpes simplex virus. Nature (1966) 2.61
Method for the isolation of highly purified Salmonella flagellins. J Clin Microbiol (1985) 2.27
An approach to evolutionary relationships of mammalian DNA viruses through analysis of the pattern of nearest neighbor base sequences. Cold Spring Harb Symp Quant Biol (1966) 2.20
Role of assays for parathyroid-hormone-related protein in investigation of hypercalcaemia. Lancet (1992) 2.17
Smoking and periductal mastitis. BMJ (1993) 2.16
A new DNA-exonuclease in cells infected with herpes virus: partial purification and properties of the enzyme. J Gen Virol (1968) 2.12
Profound motor blockade with epidural ropivacaine following spinal bupivacaine. Anaesthesia (1999) 2.02
The retinoblastoma gene is frequently altered leading to loss of expression in primary breast tumours. Oncogene (1989) 2.02
The West Midlands co-operative trial of adjuvant chemotherapy for operable breast cancer. Cancer Treat Rev (1979) 1.96
Avoidance of anencephalic and spina bifida births by maternal serum-alphafetoprotein screening. Lancet (1978) 1.90
Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City. JAMA (1986) 1.90
Urine screening for leucocytes and bacteria by dipstick and reflectance spectrophotometry. Med Lab Sci (1989) 1.87
Suicidal insulin overdose managed by excision of insulin injection site. Br Med J (Clin Res Ed) (1982) 1.86
Serum 1,25-dihydroxyvitamin D may be related inversely to disease activity in breast cancer patients with bone metastases. J Clin Endocrinol Metab (1997) 1.79
Thyroid function in adults with Down's syndrome. J Clin Endocrinol Metab (1977) 1.78
Modifying the request behaviour of clinicians. J Clin Pathol (1992) 1.78
Tamm-Horsfall urinary glycoprotein. The chemical composition. Biochem J (1970) 1.77
HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods. J Clin Pathol (2011) 1.73
Impaired action of thyroid hormone associated with smoking in women with hypothyroidism. N Engl J Med (1995) 1.73
Human cerebral hemispheres develop at different rates and ages. Science (1987) 1.68
Leucocyte esterase-nitrite screening method for pyuria and bacteriuria. J Clin Pathol (1985) 1.67
Wide local excision as the sole primary treatment in elderly patients with carcinoma of the breast. Br J Surg (1989) 1.66
The localization of laminin mRNA and protein in the postimplantation embryo and placenta of the mouse: an in situ hybridization and immunocytochemical study. Development (1988) 1.64
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas. J Pathol (1999) 1.61
Ectopic hormone production by non-endocrine tumours. Clin Endocrinol (Oxf) (1974) 1.56
Effect of educational feedback on clinicians' requesting of cardiac enzymes. Ann Clin Biochem (1992) 1.55
Lung tumours and ACTH production. Clin Endocrinol (Oxf) (1977) 1.54
Effects of magnesium on the dynamic instability of individual microtubules. Biochemistry (1990) 1.54
Pathological and biological features of mammographically detected invasive breast carcinomas. Br J Cancer (1995) 1.54
Semi-automated radioimmunoassays for total serum thyroxine and triiodothyronine. Clin Chim Acta (1975) 1.53
Identification of microtubule binding sites in the Ncd tail domain. Biochemistry (1999) 1.51
Parity and breast cancer: evidence of a dual effect. Br Med J (1980) 1.49
Abdominal symptoms, hypercalcaemia and apathetic hyperthyroidism: treatment with pamidronate. Br J Clin Pract (1994) 1.47
Immunoreactive corticotrophin levels in adrenocortical insufficiency. Br Med J (1971) 1.46
There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in situ, and invasive breast lesions. J Clin Pathol (2003) 1.46
Tests of prolactin secretion in diagnosis of prolactinomas. Lancet (1979) 1.45
Nearest neighbour base sequence analysis of the deoxyribonucleic acids of a further three mammalian viruses: Simian virus 40, human papilloma virus and adenovirus type 2. J Gen Virol (1967) 1.45
Breast abscesses and cigarette smoking. Br J Surg (1992) 1.43
Parathyroid hormone and parathyroid hormone-related protein in the investigation of hypercalcaemia in two hospital populations. Clin Endocrinol (Oxf) (1994) 1.42
Wound infiltration of local anaesthetic after lower segment caesarean section. Anaesthesia (1991) 1.42
Brain microtubule-associated proteins modulate microtubule dynamic instability in vitro. Real-time observations using video microscopy. J Cell Sci (1992) 1.41
Feedback of laboratory usage and cost data to clinicians: does it alter requesting behaviour? Ann Clin Biochem (1991) 1.39
Pituitary peptide. Nat New Biol (1973) 1.39
The clinical significance of the pattern of elevated serum carcinoembryonic antigen (CEA) levels in recurrent colorectal cancer. Br J Surg (1980) 1.38
Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas. Oncogene (1991) 1.36
Dynamic instability of microtubules. Bioessays (1987) 1.36
A critical evaluation of separation methods in radiommunoassay for total triiodothyronine and thyroxine in unextracted human serum. Ann Clin Biochem (1974) 1.34
Developmental changes in the responses of the adrenal glands of foetal sheep to endogenous adrenocorticotrophin, as indicated by hormone responses to hypoxaemia. J Endocrinol (1977) 1.31
Parathyroid hormone related protein and skeletal morbidity in breast cancer. Eur J Cancer (1992) 1.31
Radioimmunoassay of human myelin basic protein in tissue extract, cerebrospinal fluid and serum and its clinical application to patients with head injury. Clin Chim Acta (1978) 1.31
Development and validation of a radioimmunoassay for peptides related to beta-melanocyte-stimulating hormone in human plasma: the lipotropins. J Clin Endocrinol Metab (1975) 1.30
A metastable intermediate state of microtubule dynamic instability that differs significantly between plus and minus ends. J Cell Biol (1997) 1.27
Effect of fenclofenac on thyroid-function tests. Lancet (1980) 1.27
Histological detection of oestrogen receptor in human breast carcinomas. Lancet (1980) 1.26
Audit and follow-up of chronic benzodiazepine tranquillizer use in one general practice. Fam Pract (1990) 1.25
Laboratory assessment of prolactin status. Ann Clin Biochem (1979) 1.25
Herpes virus-specified proteins. In: strategy of the viral genome. Ciba Found Symp (1971) 1.22
Clinical and laboratory evaluation of four methods of assessing free thyroxine status in thyroid clinic patients. Ann Clin Biochem (1980) 1.22
Development and validation of an immunoradiometric assay of parathyrin-related protein in unextracted plasma. Clin Chem (1991) 1.22
Impact of a national external quality assessment scheme for breast pathology in the UK. J Clin Pathol (2006) 1.22
Evaluation of nucleic acid-based test (PACE 2C) for simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in endocervical specimens. J Clin Microbiol (1995) 1.21
Tumor and plasma ACTH concentrations in patients with and without the ectopic ACTH syndrome. Clin Endocrinol (Oxf) (1972) 1.21
The acid and enzymic hydrolysis of O-acetylated sialic acid residues from rabbit Tamm-Horsfall glycoprotein. Biochem J (1972) 1.20
Tamm-Horsfall urinary glycoprotein. The subunit structure. Biochem J (1970) 1.20
Changes in plasma ACTH and corticosteroid of the maternal and fetal sheep during hypoxia. Endocrinology (1974) 1.20
Helicopter cooling of heatstroke victims. Aviat Space Environ Med (1987) 1.19
Detection of HER2 amplification in circulating free DNA in patients with breast cancer. Br J Cancer (2011) 1.19
Survivin is an independent predictor of short-term survival in poor prognostic breast cancer patients. Br J Cancer (2007) 1.19
Effect of lithium on hypothalamic-pituitary-thyroid function in patients with affective disorders. Br Med J (1975) 1.17
Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells. J Pathol (2003) 1.16
The chemical composition and electron microscopic appearance of a protein derived from urinary casts. Biochim Biophys Acta (1970) 1.16
Demonstration of carcinoembryonic antigen in human breast carcinomas by the immunoperoxidase technique. J Clin Pathol (1980) 1.13
Treatment of a malignant pancreatic endocrine tumour secreting parathyroid hormone related protein. BMJ (1990) 1.11
New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast. J Pathol (2007) 1.11
Production and characterisation of antisera to diphenylhydantoin suitable for radioimmunoassay. J Immunol Methods (1976) 1.10
Immunological relationships between Salmonella flagellins and between these and flagellins from other species of Enterobacteriaceae. Med Microbiol Immunol (1985) 1.10
Grouping of streptococci by Streptex. J Clin Pathol (1979) 1.10
Perfluorochemicals: potential sources of and migration from food packaging. Food Addit Contam (2005) 1.10
Recommended units for reporting drug concentrations in biological fluids. Lancet (1986) 1.10
Multiple hormones in a bronchial tumor. J Clin Endocrinol Metab (1974) 1.09
NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation. Am J Transplant (2006) 1.09
Ulex europeus I--peroxidase as a marker of vascular endothelium: its application in routine histopathology. J Pathol (1985) 1.09
ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment. Clin Endocrinol (Oxf) (1973) 1.08
Ca2+/calmodulin regulation of the Arabidopsis kinesin-like calmodulin-binding protein. Cell Motil Cytoskeleton (1998) 1.07
Interaction between thyrotrophin, corticotrophin and growth hormone secretion in man. J Endocrinol (1971) 1.06
Characterization of the deoxyribonuclease activity induced by infection with herpes virus. Biochem J (1967) 1.06
Angiogenesis and non-small cell lung cancer. Lung Cancer (2000) 1.06
Video-enhanced differential interference contrast light microscopy. Biotechniques (1989) 1.05