CB2 receptors in reproduction.

CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol (2010) 2.74

Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91

Is lipid signaling through cannabinoid 2 receptors part of a protective system? Prog Lipid Res (2011) 1.60

Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. Br J Pharmacol (2010) 1.45

The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. Proc Natl Acad Sci U S A (2009) 1.08

Comprehensive profiling of the human circulating endocannabinoid metabolome: clinical sampling and sample storage parameters. Clin Chem Lab Med (2008) 1.06

Histomorphometric evaluation of cannabinoid receptor and anandamide modulating enzyme expression in the human endometrium through the menstrual cycle. Histochem Cell Biol (2010) 0.94

Differences in the endocannabinoid system of sperm from fertile and infertile men. PLoS One (2012) 0.85

The second intracellular loop of the human cannabinoid CB2 receptor governs G protein coupling in coordination with the carboxyl terminal domain. PLoS One (2013) 0.81

Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. PLoS One (2012) 0.79

The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. PLoS One (2011) 0.78

Acute Toxicity Associated with Use of 5F-Derivations of Synthetic Cannabinoid Receptor Agonists with Analytical Confirmation. J Med Toxicol (2016) 0.75

Spontaneous Cannabinoid Receptor 2 (CB2) Expression in the Cochlea of Adult Albino Rat and Its Up-Regulation after Cisplatin Treatment. PLoS One (2016) 0.75

Amniotic Fluid Stem Cells: A Novel Source for Modeling of Human Genetic Diseases. Int J Mol Sci (2016) 0.75

Lipid rafts and signal transduction. Nat Rev Mol Cell Biol (2000) 25.87

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev (2002) 8.50

Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci U S A (2002) 5.33

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci U S A (1999) 5.11

Leptin. Annu Rev Physiol (2000) 4.78

Adverse effects of cannabis. Lancet (1998) 4.58

Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science (1999) 4.31

Molecular cues to implantation. Endocr Rev (2004) 4.21

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol (2003) 3.60

Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology (2004) 2.18

Fatty acid amide hydrolase deficiency limits early pregnancy events. J Clin Invest (2006) 1.86

Cannabinoid signalling. Life Sci (2005) 1.83

Infection and prematurity and the role of preventive strategies. Semin Neonatol (2002) 1.78

Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions. Nat Med (1998) 1.78

Transcriptome analysis of mouse stem cells and early embryos. PLoS Biol (2003) 1.75

Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. J Biol Chem (2003) 1.70

Caveolin-1 is a negative regulator of caveolae-mediated endocytosis to the endoplasmic reticulum. J Biol Chem (2001) 1.66

Aberrant cannabinoid signaling impairs oviductal transport of embryos. Nat Med (2004) 1.52

Lipid rafts control signaling of type-1 cannabinoid receptors in neuronal cells. Implications for anandamide-induced apoptosis. J Biol Chem (2005) 1.52

Cannabinoid receptor as a novel target for the treatment of prostate cancer. Cancer Res (2005) 1.47

Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. Br J Pharmacol (2003) 1.47

Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways. FEBS Lett (2004) 1.34

Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat Genet (1997) 1.30

Jekyll and hyde: two faces of cannabinoid signaling in male and female fertility. Endocr Rev (2006) 1.25

The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanism. Mol Pharmacol (2006) 1.24

Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling. Br J Pharmacol (2005) 1.20

The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. Proc Natl Acad Sci U S A (1995) 1.18

Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction. J Cell Sci (2005) 1.18

Dysregulated cannabinoid signaling disrupts uterine receptivity for embryo implantation. J Biol Chem (2001) 1.14

Cannabinoid ligand-receptor signaling in the mouse uterus. Proc Natl Acad Sci U S A (1995) 1.12

Cloning and molecular characterization of the rat CB2 cannabinoid receptor. Biochim Biophys Acta (2002) 1.12

N-Acylethanolamines in human reproductive fluids. Chem Phys Lipids (2002) 1.11

Lipids, lipid rafts and caveolae: their importance for GPCR signaling and their centrality to the endocannabinoid system. Life Sci (2005) 1.11

New insights into endocannabinoid degradation and its therapeutic potential. Mini Rev Med Chem (2006) 1.10

Nitric oxide and its role during pregnancy: from ovulation to delivery. Curr Pharm Des (2003) 1.10

Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival. FASEB J (2000) 1.09

Neonatal body proportionality and body composition after in utero exposure to cocaine and marijuana. J Pediatr (1990) 1.09

Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function. J Clin Endocrinol Metab (2004) 1.09

Depression of plasma testosterone levels after chronic intensive marihuana use. N Engl J Med (1974) 1.08

Gynecomastia in marihuana users. N Engl J Med (1972) 1.08

Bacterial lipopolysaccharide-mediated fetal death. Production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide. J Clin Invest (1995) 1.08

Evidence that anandamide-signaling regulates human sperm functions required for fertilization. Mol Reprod Dev (2002) 1.06

Prenatal marijuana use and neonatal outcome. Neurotoxicol Teratol (1991) 1.05

The conformation, location, and dynamic properties of the endocannabinoid ligand anandamide in a membrane bilayer. J Biol Chem (2005) 1.05

Nitric oxide synthase and nitrite production in human spermatozoa: evidence that endogenous nitric oxide is beneficial to sperm motility. Mol Hum Reprod (1996) 1.04

Cytokines and implantation. Rev Reprod (1998) 1.03

The immunological pregnancy protective effect of progesterone is manifested via controlling cytokine production. Am J Reprod Immunol (1996) 1.02

Marijuana use during pregnancy and decreased length of gestation. Am J Obstet Gynecol (1984) 1.01

N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation. J Biol Chem (2005) 1.00

The chemistry of endocannabinoids. J Endocrinol Invest (2006) 0.99

Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. J Immunol (2006) 0.99

Inducible nitric oxide synthase in the rat testis: evidence for potential roles in both normal function and inflammation-mediated infertility. Biol Reprod (2000) 0.99

A tale of two cells: endocannabinoid-signaling regulates functions of neurons and sperm. Biol Reprod (2005) 0.98

Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. Biol Reprod (1998) 0.98

Cannabis, cannabinoids and reproduction. Prostaglandins Leukot Essent Fatty Acids (2004) 0.97

Homology models of the cannabinoid CB1 and CB2 receptors. A docking analysis study. Eur J Med Chem (2005) 0.96

Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. Mol Hum Reprod (2004) 0.95

Effect of marijuana use in pregnancy on fetal growth. Am J Epidemiol (1986) 0.95

Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. Biol Reprod (1996) 0.94

Cannabinoids and the human uterus during pregnancy. Am J Obstet Gynecol (2004) 0.94

Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. Endocrinology (2003) 0.94

Lipid rafts, the sarcoplasmic reticulum and uterine calcium signalling: an integrated approach. J Physiol (2005) 0.94

Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. Prostaglandins Other Lipid Mediat (2006) 0.92

NMR structural comparison of the cytoplasmic juxtamembrane domains of G-protein-coupled CB1 and CB2 receptors in membrane mimetic dodecylphosphocholine micelles. J Biol Chem (2004) 0.92

Nitric oxide is a signaling molecule in spermatozoa. Curr Pharm Des (2003) 0.91

Compartmentalisation of the sperm plasma membrane: a FRAP, FLIP and SPFI analysis of putative diffusion barriers on the sperm head. J Cell Sci (2004) 0.90

The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy. Hum Reprod Update (2007) 0.89

Marihuana smoking suppresses luteinizing hormone in women. J Pharmacol Exp Ther (1986) 0.89

Potential use of genetically modified pigs as organ donors for transplantation into humans. Clin Exp Pharmacol Physiol (1999) 0.89

Substance misuse in early pregnancy and relationship to fetal outcome. Eur J Pediatr (1999) 0.89

Stimulation of peripheral cannabinoid receptor CB2 induces MCP-1 and IL-8 gene expression in human promyelocytic cell line HL60. FEBS Lett (1999) 0.88

Reproductive biology: fatty link to fertility. Nature (2005) 0.87

Anandamide hydrolase: a guardian angel of human reproduction? Trends Pharmacol Sci (2004) 0.87

Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. Endocrinology (2006) 0.86

Characterization of the endocannabinoid system in early human pregnancy. J Clin Endocrinol Metab (2004) 0.86

Acute effects of smoking marijuana on hormones, subjective effects and performance in male human subjects. Pharmacol Biochem Behav (1986) 0.85

Tyrosine nitration in human spermatozoa: a physiological function of peroxynitrite, the reaction product of nitric oxide and superoxide. Mol Hum Reprod (2001) 0.85

Fluctuations of fatty acid amide hydrolase and anandamide levels during the human ovulatory cycle. Gynecol Endocrinol (2004) 0.85

Sperm nitric oxide and motility: the effects of nitric oxide synthase stimulation and inhibition. Mol Hum Reprod (1997) 0.85

Expression of endothelial nitric oxide synthase in the Sertoli cells of men with infertility of various causes. BJU Int (2001) 0.83

A prospective study of the effects of female and male marijuana use on in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT) outcomes. Am J Obstet Gynecol (2006) 0.82

Immuno-endocrine interactions in early pregnancy. Hum Reprod (1995) 0.82

Influence of progesterone on boar sperm capacitation. J Endocrinol (1995) 0.82

Effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro. Fertil Steril (2006) 0.82

Lipid rafts: a nexus for endocannabinoid signaling? Life Sci (2005) 0.81

Use of in vitro systems to study male germ cell development in neonatal rats. Theriogenology (1998) 0.81

Idiopathic infertility: susceptibility of spermatozoa to in-vitro capacitation, in the presence and the absence of palmitylethanolamide (a homologue of anandamide), is strongly correlated with membrane polarity studied by Laurdan fluorescence. Mol Hum Reprod (2003) 0.80

Acute effects of marihuana smoking on prolactin levels in human females. J Pharmacol Exp Ther (1985) 0.80

Cannabinoid receptor type 2 agonists induce transcription of the mu-opioid receptor gene in Jurkat T cells. Mol Pharmacol (2006) 0.79

The effects of marijuana use during pregnancy. II. A study in a low-risk home-delivery population. Drug Alcohol Depend (1983) 0.79

THC: moderation during implantation. Nat Med (2004) 0.79

Effects of marijuana on neuroendocrine hormones in human males and females. NIDA Res Monogr (1984) 0.78

Changes in human spermatozoa associated with high dose marihuana smoking. Adv Biosci (1980) 0.78

Effects of marijuana on human pregnancy, labor, and delivery. Neurobehav Toxicol Teratol (1982) 0.78

Cannabis in early pregnancy. Lancet (1967) 0.77

Identification of capacitation in boar spermatozoa by chlortetracycline staining. Theriogenology (1996) 0.77

Chronic effects of marihuana smoking on luteinizing hormone, follicle-stimulating hormone and prolactin levels in human males. Drug Alcohol Depend (1992) 0.76

Abnormalities in offspring associated with prenatal marihuana exposure. Dev Pharmacol Ther (1985) 0.76

Comparison of the inhibitory action of delta-9-tetrahydrocannabinol and petroleum spirit extract of herbal cannabis on human sperm motility. Hum Toxicol (1982) 0.76

Observations in chronic hashish users: nuclear aberrations in blood and sperm and abnormal acrosomes in spermatozoa. Adv Biosci (1980) 0.76

Good news for CB1 receptors: endogenous agonists are in the right place. Br J Pharmacol (2007) 0.84

Redox regulation and the metabolic syndrome. Cell Death Differ (2011) 0.76