Published in J Gene Med on November 01, 2007
Reversal of type 1 diabetes in mice by brown adipose tissue transplant. Diabetes (2012) 1.36
In vivo inhibition of focal adhesion kinase causes insulin resistance. J Physiol (2008) 0.86
Insulin-independent reversal of type 1 diabetes in nonobese diabetic mice with brown adipose tissue transplant. Am J Physiol Endocrinol Metab (2015) 0.84
Gene therapy for type 1 diabetes mellitus in rats by gastrointestinal administration of chitosan nanoparticles containing human insulin gene. World J Gastroenterol (2008) 0.80
Adiponectin gene therapy ameliorates high-fat, high-sucrose diet-induced metabolic perturbations in mice. Nutr Diabetes (2012) 0.80
Adiponectin-SOGA Dissociation in Type 1 Diabetes. J Clin Endocrinol Metab (2015) 0.79
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Benefits of healthy adipose tissue in the treatment of diabetes. World J Diabetes (2014) 0.77
Therapeutic value of brown adipose tissue: Correcting metabolic disease through generating healthy fat. Adipocyte (2012) 0.77
Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse model. BMC Complement Altern Med (2016) 0.75
Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis. Sci Rep (2017) 0.75
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab (2011) 2.42
Brain serotonin transporter density and aggression in abstinent methamphetamine abusers. Arch Gen Psychiatry (2006) 1.93
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J (2002) 1.73
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress. J Hypertens (2005) 1.61
Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr Med Chem (2007) 1.53
Time-dependent central compensatory mechanisms of finger dexterity after spinal cord injury. Science (2007) 1.47
Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon. J Control Release (2012) 1.46
Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines. Nat Mater (2010) 1.45
Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms. Am J Psychiatry (2003) 1.41
Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model. Hypertension (2004) 1.22
Neuronal circuit remodeling in the contralateral cortical hemisphere during functional recovery from cerebral infarction. J Neurosci (2009) 1.20
Stimulated HSP90 binding to eNOS and activation of the PI3-Akt pathway contribute to globular adiponectin-induced NO production: vasorelaxation in response to globular adiponectin. Biochem Biophys Res Commun (2005) 1.14
Effect of nanoscale curvature of single-walled carbon nanotubes on adsorption of polycyclic aromatic hydrocarbons. Nano Lett (2007) 1.14
Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes. Am J Physiol Heart Circ Physiol (2008) 1.14
Age-related changes in cerebral blood flow and glucose metabolism in conscious rhesus monkeys. Brain Res (2002) 1.11
Reduction of serotonin transporters of patients with chronic fatigue syndrome. Neuroreport (2004) 1.11
PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation. Life Sci (2008) 1.09
Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury. Circulation (2003) 1.09
Porous lanthanide-organic frameworks: synthesis, characterization, and unprecedented gas adsorption properties. J Am Chem Soc (2003) 1.07
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR180711. Biol Psychiatry (2007) 1.06
Evaluation of 3'-deoxy-3'-18F-fluorothymidine for monitoring tumor response to radiotherapy and photodynamic therapy in mice. J Nucl Med (2004) 1.05
Pioglitazone treatment of insulin resistance in a patient with Werner's syndrome. Diabetes Care (2004) 1.05
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am J Nephrol (2003) 1.05
Design of folate-linked liposomal doxorubicin to its antitumor effect in mice. Clin Cancer Res (2008) 1.04
Effect of polyethylene glycol linker chain length of folate-linked microemulsions loading aclacinomycin A on targeting ability and antitumor effect in vitro and in vivo. Clin Cancer Res (2005) 1.03
Buthionine sulfoximine causes endothelium dependent hyper-relaxation and hypoadiponectinemia. Life Sci (2006) 1.02
Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes. Am J Physiol Heart Circ Physiol (2007) 1.02
Neural substrates of human facial expression of pleasant emotion induced by comic films: a PET Study. Neuroimage (2002) 1.02
Evaluation of D-18F-FMT, 18F-FDG, L-11C-MET, and 18F-FLT for monitoring the response of tumors to radiotherapy in mice. J Nucl Med (2009) 1.02
Cationic liposome (DC-Chol/DOPE=1:2) and a modified ethanol injection method to prepare liposomes, increased gene expression. Int J Pharm (2007) 1.02
Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome. J Biol Chem (2010) 1.01
Alterations in EDHF-type relaxation and phosphodiesterase activity in mesenteric arteries from diabetic rats. Am J Physiol Heart Circ Physiol (2003) 1.01
Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver. Mol Ther (2003) 1.01
Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium. Endocrinology (2010) 1.01
Preparation and characterization of superparamagnetic iron oxide nanoparticles stabilized by alginate. Int J Pharm (2006) 1.00
Efficient microwave-assisted prenylation of pinostrobin and biological evaluation of its derivatives as antitumor agents. Bioorg Med Chem Lett (2010) 0.99
Adiponectin induces NF-kappaB activation that leads to suppression of cytokine-induced NF-kappaB activation in vascular endothelial cells: globular adiponectin vs. high molecular weight adiponectin. Diab Vasc Dis Res (2008) 0.99
Retracted Hypoadiponectinemia is caused by chronic blockade of nitric oxide synthesis in rats. Metabolism (2005) 0.99
T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes. Int J Pharm (2010) 0.99
Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses. Clin Exp Metastasis (2002) 0.99
Mechanisms underlying enhanced contractile response to endothelin-1 in diabetic rat basilar artery. Peptides (2004) 0.99
Aldosterone impairs vascular endothelial cell function. J Cardiovasc Pharmacol (2006) 0.98
Medial orbitofrontal cortex is associated with fatigue sensation. Neurol Res Int (2010) 0.97
Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther (2005) 0.97
Protective effects of minocycline on the reduction of dopamine transporters in the striatum after administration of methamphetamine: a positron emission tomography study in conscious monkeys. Biol Psychiatry (2006) 0.96
Default mode of brain activity demonstrated by positron emission tomography imaging in awake monkeys: higher rest-related than working memory-related activity in medial cortical areas. J Neurosci (2009) 0.96
Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat. Med Sci Monit (2002) 0.96
Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat. Am J Physiol Heart Circ Physiol (2009) 0.96
Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography. J Neurosci Res (2006) 0.95
Enhanced antitumor effect of camptothecin loaded in long-circulating polymeric micelles. J Control Release (2006) 0.95
Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in mice. Am J Pathol (2010) 0.95
Enhancement of anticancer activity in antineovascular therapy is based on the intratumoral distribution of the active targeting carrier for anticancer drugs. Biol Pharm Bull (2006) 0.95
Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. Regul Pept (2009) 0.94
Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting. Pharm Res (2004) 0.94
Cilostazol activates AMP-activated protein kinase and restores endothelial function in diabetes. Am J Hypertens (2008) 0.94
The PI3-K/Akt pathway: roles related to alterations in vasomotor responses in diabetic models. J Smooth Muscle Res (2005) 0.94
Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: effect of chain length and amount of folate-PEG linker. J Drug Target (2008) 0.94
In vivo antitumor activity of camptothecin incorporated in liposomes formulated with an artificial lipid and human serum albumin. J Control Release (2008) 0.94
Globular adiponectin induces adhesion molecule expression through the sphingosine kinase pathway in vascular endothelial cells. Life Sci (2007) 0.93
α1-Adrenoceptors and muscarinic receptors in voiding function - binding characteristics of therapeutic agents in relation to the pharmacokinetics. Br J Clin Pharmacol (2011) 0.93
Modulations of shear stress-induced contractile responses and agonist-induced vasodilation in hypercholesterolemic rats. Atherosclerosis (2004) 0.93
Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability. Int J Pharm (2006) 0.93
Ventricular fibrillation due to severe hypokalemia induced by steroid treatment in a patient with thyrotoxic periodic paralysis. Intern Med (2006) 0.93
Folate-linked lipid-based nanoparticle for targeted gene delivery. Curr Drug Deliv (2005) 0.92
Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts. Eur J Pharm Biopharm (2008) 0.92
Novel chitosan particles and chitosan-coated emulsions inducing immune response via intranasal vaccine delivery. Pharm Res (2004) 0.92
Superparamagnetic iron oxide nanoparticles stabilized by alginate: pharmacokinetics, tissue distribution, and applications in detecting liver cancers. Int J Pharm (2007) 0.92
Multitracer study with positron emission tomography in Creutzfeldt-Jakob disease. Eur J Nucl Med Mol Imaging (2002) 0.92
Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect. J Control Release (2006) 0.92
Influence of serum and albumins from different species on stability of camptothecin-loaded micelles. J Control Release (2005) 0.92
Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres. J Control Release (2006) 0.92
Glucose upregulates plasminogen activator inhibitor-1 gene expression in vascular smooth muscle cells. Life Sci (2002) 0.92
Dysfunction of endothelium-dependent relaxation to insulin via PKC-mediated GRK2/Akt activation in aortas of ob/ob mice. Am J Physiol Heart Circ Physiol (2011) 0.91
Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes. Br J Pharmacol (2010) 0.91