PubRank

Linda Wooldridge

Author PubWeight™ 35.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med 2005 3.63
2 Structural and kinetic basis for heightened immunogenicity of T cell vaccines. J Exp Med 2005 2.22
3 Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties. J Biol Chem 2007 1.95
4 The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. J Biol Chem 2003 1.92
5 Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. J Immunol Methods 2008 1.62
6 Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition. J Immunol 2010 1.48
7 Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat Immunol 2012 1.46
8 Concern Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy. Front Immunol 2013 1.41
9 Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 2011 1.39
10 High avidity antigen-specific CTL identified by CD8-independent tetramer staining. J Immunol 2003 1.28
11 Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers. Cytometry A 2008 1.26
12 Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathog 2010 1.18
13 Profound inhibition of antigen-specific T-cell effector functions by dasatinib. Clin Cancer Res 2008 1.15
14 Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 2012 1.13
15 Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers. J Immunol Methods 2008 1.03
16 Coreceptor CD8-driven modulation of T cell antigen receptor specificity. J Theor Biol 2007 1.00
17 T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. J Biol Chem 2012 0.96
18 Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. J Immunol 2011 0.94
19 The molecular determinants of CD8 co-receptor function. Immunology 2012 0.94
20 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J Clin Invest 2016 0.90
21 Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity. Diabetes 2012 0.89
22 Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor. Eur J Immunol 2007 0.87
23 Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Front Immunol 2013 0.81
24 The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses. PLoS One 2013 0.80
25 The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells. J Leukoc Biol 2011 0.80
26 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J Clin Invest 2016 0.76
27 Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity. Eur J Immunol 2012 0.76
28 Framework for veterinary education and training. Vet Rec 2003 0.75
29 ELISPOT and functional T cell analyses using HLA mono-specific target cells. J Immunol Methods 2009 0.75