PubRank

Luca G Guidotti

Author PubWeight™ 44.59‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature 2010 3.71
2 Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. Proc Natl Acad Sci U S A 2012 3.50
3 Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nat Med 2005 2.19
4 Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell 2008 1.80
5 Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice. J Leukoc Biol 2006 1.73
6 In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance. Blood 2007 1.69
7 MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs. J Clin Invest 2004 1.65
8 Immune tolerance split between hepatitis B virus precore and core proteins. J Virol 2005 1.63
9 Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity 2013 1.62
10 A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen. Proc Natl Acad Sci U S A 2004 1.61
11 Bone marrow as an alternative site for islet transplantation. Blood 2009 1.61
12 Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. J Virol 2002 1.61
13 Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice. Proc Natl Acad Sci U S A 2002 1.51
14 Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus. Proc Natl Acad Sci U S A 2008 1.48
15 Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients. J Immunol 2006 1.44
16 Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes. J Virol 2003 1.39
17 Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. PLoS Pathog 2011 1.34
18 Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice. J Immunol 2002 1.34
19 Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes. Proc Natl Acad Sci U S A 2002 1.29
20 Follicular helper NKT cells induce limited B cell responses and germinal center formation in the absence of CD4(+) T cell help. J Immunol 2012 1.22
21 HBV pathogenesis in animal models: recent advances on the role of platelets. J Hepatol 2007 1.20
22 Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus. Clin Vaccine Immunol 2007 1.04
23 Role of CCL2/MCP-1 in islet transplantation. Cell Transplant 2010 1.01
24 TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb. EMBO Mol Med 2013 0.99
25 Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma. J Hepatol 2013 0.92
26 Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes. Adv Exp Med Biol 2010 0.89
27 Bisphosphonates target B cells to enhance humoral immune responses. Cell Rep 2013 0.83
28 Reduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines. Hepatol Res 2006 0.78
29 On the role of platelets in the pathogenesis of viral hepatitis. J Hepatol 2009 0.78
30 Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy. Antivir Ther 2006 0.78
31 The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver. Hepatology 2014 0.75