Lumbar degenerative disk disease.

PubWeight™: 1.88‹?› | Rank: Top 3%

🔗 View Article (PMID 17885180)

Published in Radiology on October 01, 2007

Authors

Michael T Modic1, Jeffrey S Ross

Author Affiliations

1: Division of Radiology, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA. modicm1@ccf.org

Articles citing this

Macrophage imaging by USPIO-enhanced MR for the differentiation of infectious osteomyelitis and aseptic vertebral inflammation. Eur Radiol (2009) 1.58

Relationship between spinal magnetic resonance imaging findings and candidacy for spinal surgery. Can Fam Physician (2010) 1.45

Lack of relationship between occupational workload and microscopic alterations in lumbar intervertebral disc disease. Open Orthop J (2014) 1.38

Lumbar spinal stenosis: syndrome, diagnostics and treatment. Nat Rev Neurol (2009) 1.22

T1rho and T2 relaxation times for lumbar disc degeneration: an in vivo comparative study at 3.0-Tesla MRI. Eur Radiol (2012) 1.15

Lumbar intervertebral disc abnormalities: comparison of quantitative T2 mapping with conventional MR at 3.0 T. Eur Radiol (2010) 1.08

Relationship between annular tear and presence of Propionibacterium acnes in lumbar intervertebral disc. Eur Spine J (2015) 1.06

Biomechanics of intervertebral disk degeneration. Orthop Clin North Am (2011) 1.04

Is the development of Modic changes associated with clinical symptoms? A 14-month cohort study with MRI. Eur Spine J (2012) 1.02

Genetic risk factors of disc degeneration among 12-14-year-old Danish children: a population study. Int J Mol Epidemiol Genet (2010) 0.99

Relationship of Modic type 1 change with disc degeneration: a prospective MRI study. Skeletal Radiol (2008) 0.99

Lumbar disc degenerative disease: disc degeneration symptoms and magnetic resonance image findings. Asian Spine J (2013) 0.99

Modic Changes and Disc Degeneration Caused by Inoculation of Propionibacterium acnes inside Intervertebral Discs of Rabbits: A Pilot Study. Biomed Res Int (2016) 0.99

Imaging of lumbar degenerative disk disease: history and current state. Skeletal Radiol (2011) 0.99

Genetic association studies in lumbar disc degeneration: a systematic review. PLoS One (2012) 0.97

Are Modic changes prognostic for recovery in a cohort of patients with non-specific low back pain? Eur Spine J (2011) 0.97

Posterior dynamic stabilization of the lumbar spine with the Accuflex rod system as a stand-alone device: experience in 20 patients with 2-year follow-up. Eur Spine J (2010) 0.96

Age related reduction of T1rho and T2 magnetic resonance relaxation times of lumbar intervertebral disc. Quant Imaging Med Surg (2014) 0.88

Three-dimensional morphological and signal intensity features for detection of intervertebral disc degeneration from magnetic resonance images. J Am Med Inform Assoc (2013) 0.88

Do more MRI findings imply worse disability or more intense low back pain? A cross-sectional study of candidates for lumbar disc prosthesis. Skeletal Radiol (2013) 0.86

Reliability of MRI findings in candidates for lumbar disc prosthesis. Neuroradiology (2011) 0.85

Disc degeneration and chronic low back pain: an association which becomes nonsignificant when endplate changes and disc contour are taken into account. Neuroradiology (2013) 0.84

The characteristics of spinopelvic sagittal alignment in patients with lumbar disc degenerative diseases. Eur Spine J (2013) 0.83

Categorization of Pathology Causing Low Back Pain using Magnetic Resonance Imaging (MRI). J Clin Diagn Res (2015) 0.82

An evidence-based diagnostic classification system for low back pain. J Can Chiropr Assoc (2013) 0.82

Long Term Efficacy of Posterior Lumbar Interbody Fusion with Standard Cages alone in Lumbar Disc Diseases Combined with Modic Changes. J Korean Neurosurg Soc (2009) 0.82

Biomechanics of disc degeneration. Adv Orthop (2012) 0.81

The NLRP3/Caspase-1/Interleukin-1β Axis Is Active in Human Lumbar Cartilaginous Endplate Degeneration. Clin Orthop Relat Res (2016) 0.80

Modic degenerative marrow changes in the thoracic spine : a single center experience. J Korean Neurosurg Soc (2013) 0.79

MRI evaluation of lumbar disc degenerative disease. J Clin Diagn Res (2015) 0.78

Lumbar intervertebral disc degeneration and related factors in Korean firefighters. BMJ Open (2016) 0.78

Propionibacterium acnes, Coagulase-Negative Staphylococcus, and the "Biofilm-like" Intervertebral Disc. Spine (Phila Pa 1976) (2016) 0.78

Association between intervertebral disc degeneration and endplate perfusion studied by DCE-MRI. Eur Spine J (2014) 0.78

Comparison between pain at discography and morphological disc changes at axial loaded MRI in patients with low back pain. Eur Spine J (2014) 0.77

Single Nucleotide Variants of Candidate Genes in Aggrecan Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes. PLoS One (2017) 0.77

MRI features of the psoas major muscle in patients with low back pain. Eur Spine J (2013) 0.77

No effect of 6-month intake of glucosamine sulfate on Modic changes or high intensity zones in the lumbar spine: sub-group analysis of a randomized controlled trial. J Negat Results Biomed (2012) 0.77

Yoga and disc degenerative disease in cervical and lumbar spine: an MR imaging-based case control study. Eur Spine J (2010) 0.77

Lumbar spine intervertebral disc gene delivery: a pilot study in lewis rats. HSS J (2013) 0.77

Prevalence of radiographic findings in individuals with chronic low back pain screened for a randomized controlled trial: secondary analysis and clinical implications. J Manipulative Physiol Ther (2014) 0.77

Does the high-intensity zone (HIZ) of lumbar Intervertebral discs always represent an annular fissure? Eur Radiol (2016) 0.76

Changes in lumbar disk morphology associated with prolonged sitting assessed by magnetic resonance imaging. PM R (2014) 0.76

A prospective multicenter phase I/II clinical trial to evaluate safety and efficacy of NOVOCART Disc plus autologous disc chondrocyte transplantation in the treatment of nucleotomized and degenerative lumbar disc to avoid secondary disease: study protocol for a randomized controlled trial. Trials (2016) 0.76

End plate disproportion and degenerative disc disease: a case-control study. Asian Spine J (2014) 0.76

Reliability of change in lumbar MRI findings over time in patients with and without disc prosthesis--comparing two different image evaluation methods. Skeletal Radiol (2012) 0.76

Does T2 mapping of the posterior annulus fibrosus indicate the presence of lumbar intervertebral disc herniation? A 3.0 Tesla magnetic resonance study. Eur Spine J (2016) 0.75

Serum lipid levels are positively correlated with lumbar disc herniation-a retrospective study of 790 Chinese patients. Lipids Health Dis (2016) 0.75

BMSC paracrine activity attenuates interleukin-1β-induced inflammation and apoptosis in rat AF cells via inhibiting relative NF-κB signaling and the mitochondrial pathway. Am J Transl Res (2017) 0.75

Associations between disc space narrowing, anterior osteophytes and disability in chronic mechanical low back pain: a cross sectional study. BMC Musculoskelet Disord (2017) 0.75

High precision semiautomated computed tomography measurement of lumbar disk and vertebral heights. Med Phys (2013) 0.75

The Use of Lumbar Spine Magnetic Resonance Imaging in Eastern China: Appropriateness and Related Factors. PLoS One (2016) 0.75

Using Magnetic Resonance Myelography to Improve Interobserver Agreement in the Evaluation of Lumbar Spinal Canal Stenosis and Root Compression. Asian Spine J (2017) 0.75

MRI follow-up of subchondral signal abnormalities in a selected group of chronic low back pain patients. Eur Spine J (2008) 0.75

Association between nutritional status and Modic classification in degenerative disc disease. J Phys Ther Sci (2016) 0.75

Are the presence of MODIC changes on MRI scans related to "improvement" in low back pain patients treated with lumbar facet joint injections? BMC Musculoskelet Disord (2015) 0.75

Meta-analysis of the effects of genetic polymorphisms on intervertebral disc degeneration. Eur Spine J (2017) 0.75

Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation. Sci Rep (2017) 0.75

Articles by these authors

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest (2003) 32.01

Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res (2005) 9.70

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol (2013) 7.97

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol (2006) 7.24

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med (2012) 6.77

Gene expression profiles in paraffin-embedded core biopsy tissue predict response to chemotherapy in women with locally advanced breast cancer. J Clin Oncol (2005) 4.03

The high-field-strength curmudgeon. AJNR Am J Neuroradiol (2004) 2.83

Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy. Clin Cancer Res (2005) 2.29

Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer. Proc Natl Acad Sci U S A (2005) 2.16

Vascular targeted therapy with anti-prostate-specific membrane antigen monoclonal antibody J591 in advanced solid tumors. J Clin Oncol (2007) 1.95

MammaPrint 70-gene signature: another milestone in personalized medical care for breast cancer patients. Expert Rev Mol Diagn (2009) 1.89

Acute low back pain and radiculopathy: MR imaging findings and their prognostic role and effect on outcome. Radiology (2005) 1.80

Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell lung cancer. J Clin Oncol (2013) 1.71

TP53 genomics predict higher clinical and pathologic tumor response in operable early-stage breast cancer treated with docetaxel-capecitabine ± trastuzumab. Breast Cancer Res Treat (2011) 1.68

Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer. J Thorac Oncol (2012) 1.66

Localized lymphedema (elephantiasis): a case series and review of the literature. J Cutan Pathol (2008) 1.66

BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition. Clin Cancer Res (2013) 1.66

Interleukin 6, a nuclear factor-kappaB target, predicts resistance to docetaxel in hormone-independent prostate cancer and nuclear factor-kappaB inhibition by PS-1145 enhances docetaxel antitumor activity. Clin Cancer Res (2006) 1.61

Concordance of genomic alterations between primary and recurrent breast cancer. Mol Cancer Ther (2014) 1.57

Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets. Cancer Discov (2013) 1.54

Spine infection/inflammation. Radiol Clin North Am (2011) 1.40

Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein. J Hematol Oncol (2014) 1.38

Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers. Hum Pathol (2009) 1.31

Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells. Mol Cancer Ther (2006) 1.30

The amplified WWP1 gene is a potential molecular target in breast cancer. Int J Cancer (2007) 1.26

Tumor suppressor genes in breast cancer: the gatekeepers and the caretakers. Am J Clin Pathol (2005) 1.25

Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trial. J Clin Oncol (2009) 1.25

Loss of claudins-1 and -7 and expression of claudins-3 and -4 correlate with prognostic variables in prostatic adenocarcinomas. Hum Pathol (2007) 1.23

Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients. J Clin Oncol (2008) 1.19

Clinical next-generation sequencing successfully applied to fine-needle aspirations of pulmonary and pancreatic neoplasms. Cancer Cytopathol (2013) 1.16

Invasion factors uPA/PAI-1 and HER2 status provide independent and complementary information on patient outcome in node-negative breast cancer. J Clin Oncol (2003) 1.14

Comparison of the predictive accuracy of DNA array-based multigene classifiers across cDNA arrays and Affymetrix GeneChips. J Mol Diagn (2005) 1.11

Inhibition of the canonical IKK/NF kappa B pathway sensitizes human cancer cells to doxorubicin. Cell Cycle (2007) 1.09

A quantitative reverse transcriptase-polymerase chain reaction assay to identify metastatic carcinoma tissue of origin. J Mol Diagn (2006) 1.08

Bortezomib (PS-341, Velcade) increases the efficacy of trastuzumab (Herceptin) in HER-2-positive breast cancer cells in a synergistic manner. Mol Cancer Ther (2006) 1.07

Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer. Ann Diagn Pathol (2004) 1.07

Actin-binding protein fascin expression in skin neoplasia. J Cutan Pathol (2002) 1.06

Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Biomark Med (2011) 1.05

Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib. J Thorac Oncol (2014) 1.02

The significance of TNFAIP8 in prostate cancer response to radiation and docetaxel and disease recurrence. Int J Cancer (2013) 0.97

RET-rearranged lung adenocarcinomas with lymphangitic spread, psammoma bodies, and clinical responses to cabozantinib. J Thorac Oncol (2014) 0.96

Randomized phase II study of weekly docetaxel plus trastuzumab versus weekly paclitaxel plus trastuzumab in patients with previously untreated advanced nonsmall cell lung carcinoma. Cancer (2005) 0.96

Prognostic significance of anti-apoptosis proteins survivin and bcl-2 in non-small cell lung carcinomas: a clinicopathologic study of 102 cases. Appl Immunohistochem Mol Morphol (2004) 0.94

Targeting the ubiquitin-proteasome pathway in breast cancer. Clin Breast Cancer (2004) 0.91

Overexpression of WWP1 is associated with the estrogen receptor and insulin-like growth factor receptor 1 in breast carcinoma. Int J Cancer (2009) 0.90

Next-generation pathology. Am J Clin Pathol (2011) 0.89

Smad4 protein expression correlates with grade, stage, and DNA ploidy in prostatic adenocarcinomas. Hum Pathol (2005) 0.89

Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging. Am J Clin Pathol (2003) 0.88

Splenic marginal zone lymphoma: a case report and review of the literature. Arch Pathol Lab Med (2002) 0.88

Comparison of HER-2/neu oncogene amplification detected by fluorescence in situ hybridization in lobular and ductal breast cancer. Appl Immunohistochem Mol Morphol (2002) 0.87

Human epidermal growth factor receptor 2 testing in 2010: does chromosome 17 centromere copy number make any difference? J Clin Oncol (2010) 0.86

The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival. Clin Cancer Res (2010) 0.85

Successful surgical intervention for the management of endocarditis due to multidrug resistant Candida parapsilosis: case report and literature review. Mycopathologia (2011) 0.84

New techniques in dermatopathology that help to diagnose and prognosticate melanoma. Clin Dermatol (2008) 0.83

Biomarkers in melanoma: stage III and IV disease. Expert Rev Mol Diagn (2005) 0.83

Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib. J Natl Cancer Inst (2015) 0.83

A Novel SDHA-deficient Renal Cell Carcinoma Revealed by Comprehensive Genomic Profiling. Am J Surg Pathol (2015) 0.82

Survivin and Bcl-2 expression in prostatic adenocarcinomas. Arch Pathol Lab Med (2004) 0.82

Saving lives with accurate HER2 testing. Am J Clin Pathol (2010) 0.81

Biomarkers in melanoma: staging, prognosis and detection of early metastases. Expert Rev Mol Diagn (2003) 0.81

Melanoma update: diagnostic and prognostic factors that can effectively shape and personalize management. Biomark Med (2011) 0.81

CD79a is heterogeneously expressed in neoplastic and normal myeloid precursors and megakaryocytes in an antibody clone-dependent manner. Am J Clin Pathol (2007) 0.81

Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion. Oncology (2016) 0.80

Biomarkers in melanoma: predisposition, screening and diagnosis. Expert Rev Mol Diagn (2003) 0.80

The time for 3T clinical imaging is now. AJNR Am J Neuroradiol (2004) 0.79

Multigene predictors in early-stage breast cancer: moving in or moving out? Expert Rev Mol Diagn (2008) 0.79

Expression of cysteine protease protein 32 in prostatic adenocarcinoma correlates with tumor grade. Arch Pathol Lab Med (2004) 0.78

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer. J Clin Invest (2016) 0.77

Measuring circulating miRNAs: the new "PSA" for Breast Cancer? Oncologist (2010) 0.77

HER2 Testing in Gastric/Gastroesophageal Junction Adenocarcinomas: Unique Features of a Familiar Test. Gastrointest Cancer Res (2011) 0.77

Determination of HER2 gene status by fully automated fluorescence microscopy. Anal Quant Cytol Histol (2011) 0.76

Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma. Oncology (2016) 0.75

Magnetic Resonance Imaging and Computed Tomography of the Brain-50 Years of Innovation, With a Focus on the Future. Invest Radiol (2015) 0.75

Prospective observational study of acute postlumbar laminectomy MRI. J Neurosurg Spine (2013) 0.75

Genomic microarrays in cancer molecular diagnostics: just biomarker discovery tools or future bedside clinical assays? Expert Rev Mol Diagn (2005) 0.75

Next-Generation Sequencing Reveals Pathway Activations and New Routes to Targeted Therapies in Cutaneous Metastatic Melanoma. Am J Dermatopathol (2017) 0.75

Improving the accuracy of hormone receptor assays in breast cancer: an unmet medical need. Future Oncol (2005) 0.75

Imaging of Spine Trauma. Neurosurgery (2016) 0.75

Fluid in the flute: Reversible hydromyelia. J Neurol Sci (2005) 0.75

Imaging of Degenerative and Infectious Conditions of the Spine. Neurosurgery (2016) 0.75

Appendiceal mucosal Schwann cell proliferation: a putative histologic marker of appendiceal diverticular disease. Int J Surg Pathol (2013) 0.75

Emerging cancer diagnostics. "On slide" or "off slide": that is the question. Am J Clin Pathol (2003) 0.75

The spectrum of grossly visible pigmented lesions in the uterine cervix: a prospective study. Int J Gynecol Pathol (2014) 0.75