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1
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Alzheimer's disease.
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Lancet
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2006
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9.15
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2
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Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease.
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Neurobiol Aging
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2003
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2.96
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3
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Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias.
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J Nucl Med
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2008
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2.92
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4
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Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism.
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Proc Natl Acad Sci U S A
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2007
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2.41
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5
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Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's.
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Proc Natl Acad Sci U S A
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2010
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2.32
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6
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Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative.
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Neuroimage
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2010
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2.29
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7
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Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal.
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Neurobiol Aging
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2008
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2.25
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8
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Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease.
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J Nucl Med
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2006
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2.17
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9
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FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease.
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Eur J Nucl Med Mol Imaging
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2009
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2.15
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10
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Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease.
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Eur J Nucl Med Mol Imaging
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2008
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2.04
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11
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Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging.
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Radiology
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2003
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2.00
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12
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Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly.
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Proc Natl Acad Sci U S A
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2003
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1.95
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13
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Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease.
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Biol Psychiatry
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2008
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1.93
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14
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Hippocampal hypometabolism predicts cognitive decline from normal aging.
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Neurobiol Aging
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2007
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1.90
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15
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Inflammation and Alzheimer's disease: possible role of periodontal diseases.
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Alzheimers Dement
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2007
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1.82
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16
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Imaging markers for Alzheimer disease: which vs how.
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Neurology
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2013
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1.76
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17
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Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease.
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JAMA Neurol
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2013
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1.75
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18
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Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints.
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Biol Psychiatry
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2007
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1.68
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19
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Surgery and brain atrophy in cognitively normal elderly subjects and subjects diagnosed with mild cognitive impairment.
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Anesthesiology
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2012
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1.67
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20
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Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment.
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Neurobiol Aging
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2007
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1.61
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21
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Does mild cognitive impairment increase the risk of developing postoperative cognitive dysfunction?
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Am J Surg
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2010
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1.51
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22
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Early detection of Alzheimer's disease using neuroimaging.
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Exp Gerontol
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2006
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1.41
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23
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Robust and conventional neuropsychological norms: diagnosis and prediction of age-related cognitive decline.
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Neuropsychology
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2008
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1.41
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24
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MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.
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Magn Reson Med
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2004
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1.37
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25
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The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer's disease.
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Alzheimers Dement
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2008
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1.33
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26
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Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging.
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J Alzheimers Dis
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2010
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1.28
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27
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Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease.
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J Alzheimers Dis
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2009
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1.26
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28
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(18)F-FDG PET database of longitudinally confirmed healthy elderly individuals improves detection of mild cognitive impairment and Alzheimer's disease.
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J Nucl Med
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2007
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1.23
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29
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Changes in brain functional homogeneity in subjects with Alzheimer's disease.
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Psychiatry Res
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2002
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1.18
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30
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Mild cognitive impairment (MCI): a historical perspective.
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Int Psychogeriatr
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2007
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1.15
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31
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Subjective memory complaints: presence, severity and future outcome in normal older subjects.
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Dement Geriatr Cogn Disord
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2007
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1.14
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32
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Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol.
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J Alzheimers Dis
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2011
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1.08
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33
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Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesis.
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J Alzheimers Dis
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2008
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1.08
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34
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The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease.
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Neurobiol Aging
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2007
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1.07
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35
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Current Challenges for the Early Detection of Alzheimer's Disease: Brain Imaging and CSF Studies.
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J Clin Neurol
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2009
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1.06
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36
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A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice.
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Neurobiol Aging
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2007
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1.06
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37
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TNF-alpha and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects.
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J Neuroimmunol
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2009
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1.05
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38
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Subjective memory complaints in aging are associated with elevated cortisol levels.
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Neurobiol Aging
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2005
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1.04
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39
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Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease.
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Neurobiol Aging
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2004
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1.03
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40
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Visual rating of medial temporal lobe metabolism in mild cognitive impairment and Alzheimer's disease using FDG-PET.
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Eur J Nucl Med Mol Imaging
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2005
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1.03
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41
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Greater risk of Alzheimer's disease in older adults with insomnia.
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J Am Geriatr Soc
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2011
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1.01
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42
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Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's.
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Biol Psychiatry
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2010
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0.98
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43
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Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders.
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Neurobiol Aging
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2010
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0.98
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44
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Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia.
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J Cereb Blood Flow Metab
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2010
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0.97
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45
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Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents.
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2012
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0.96
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46
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Absence of hippocampal volume differences in survivors of the Nazi Holocaust with and without posttraumatic stress disorder.
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Psychiatry Res
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2005
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0.96
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47
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The role of quantitative structural imaging in the early diagnosis of Alzheimer's disease.
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Neuroimaging Clin N Am
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2005
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0.95
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48
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Hippocampal atrophy disrupts transfer generalization in nondemented elderly.
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J Geriatr Psychiatry Neurol
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2002
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0.95
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49
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Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.
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Proc Natl Acad Sci U S A
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2012
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0.95
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50
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Magnetic resonance and PET studies in the early diagnosis of Alzheimer's disease.
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Expert Rev Neurother
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2004
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51
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Cerebrovascular reactivity to carbon dioxide in Alzheimer's disease.
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J Alzheimers Dis
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52
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Neuroendocrinology
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2002
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53
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Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly.
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Neurobiol Aging
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54
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Quantitation, regional vulnerability, and kinetic modeling of brain glucose metabolism in mild Alzheimer's disease.
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Eur J Nucl Med Mol Imaging
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2007
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55
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Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T.
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Magn Reson Med
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2011
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56
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Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders.
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PLoS One
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2012
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57
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Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD.
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Neurology
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2014
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0.88
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58
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Anteroposterior hippocampal metabolic heterogeneity: three-dimensional multivoxel proton 1H MR spectroscopic imaging--initial findings.
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Radiology
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2008
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59
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Biomarkers for the early diagnosis of Alzheimer's disease.
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Lancet Neurol
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Nat Rev Neurol
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Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology.
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J Alzheimers Dis
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63
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64
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Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study.
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Prog Neuropsychopharmacol Biol Psychiatry
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2008
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Resting-state glucose metabolism level is associated with the regional pattern of amyloid pathology in Alzheimer's disease.
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Nat Med
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Comparison of the Brain Volume in Essential Tremor and Parkinson's Disease Tremor Using an Automated Segmentation Method.
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