Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation.

PubWeight™: 1.29‹?› | Rank: Top 10%

🔗 View Article (PMC 2219529)

Published in Br J Pharmacol on October 01, 2007

Authors

K L Wright1, M Duncan, K A Sharkey

Author Affiliations

1: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.

Articles citing this

Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol (2009) 2.23

Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91

Cannabinoid hyperemesis syndrome. Curr Drug Abuse Rev (2011) 1.75

Is lipid signaling through cannabinoid 2 receptors part of a protective system? Prog Lipid Res (2011) 1.60

Modulating the endocannabinoid system in human health and disease--successes and failures. FEBS J (2013) 1.59

Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. Br J Pharmacol (2009) 1.55

Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilities. Philos Trans R Soc Lond B Biol Sci (2012) 1.27

The emerging role of the endocannabinoid system in cardiovascular disease. Semin Immunopathol (2009) 1.24

Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissue. PLoS One (2009) 1.16

Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. Am J Physiol Gastrointest Liver Physiol (2008) 1.10

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors. Br J Pharmacol (2008) 1.04

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice. Br J Pharmacol (2008) 1.03

Signal transduction via cannabinoid receptors. CNS Neurol Disord Drug Targets (2009) 0.99

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends Pharmacol Sci (2009) 0.99

CB2 Cannabinoid receptors as a therapeutic target-what does the future hold? Mol Pharmacol (2014) 0.93

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. Br J Pharmacol (2012) 0.93

The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. Br J Pharmacol (2010) 0.93

Modulation of gut-specific mechanisms by chronic δ(9)-tetrahydrocannabinol administration in male rhesus macaques infected with simian immunodeficiency virus: a systems biology analysis. AIDS Res Hum Retroviruses (2014) 0.92

A potential role for GPR55 in gastrointestinal functions. Curr Opin Pharmacol (2012) 0.90

Small intestinal cannabinoid receptor changes following a single colonic insult with oil of mustard in mice. Front Pharmacol (2010) 0.90

Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. Br J Pharmacol (2012) 0.90

Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complex. J Biol Chem (2014) 0.89

Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. Br J Pharmacol (2012) 0.89

β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner. Free Radic Biol Med (2012) 0.85

Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. Can J Gastroenterol (2011) 0.85

Anti-inflammatory cannabinoids in diet: Towards a better understanding of CB(2) receptor action? Commun Integr Biol (2008) 0.84

Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute simian immunodeficiency virus infection of rhesus macaques. J Virol (2014) 0.83

Cannabinoid receptor CB2 protects against balloon-induced neointima formation. Am J Physiol Heart Circ Physiol (2012) 0.83

Ethnopharmacological Survey of Plants Used in the Traditional Treatment of Gastrointestinal Pain, Inflammation and Diarrhea in Africa: Future Perspectives for Integration into Modern Medicine. Animals (Basel) (2013) 0.80

Role of Cannabinoids in Gastrointestinal Mucosal Defense and Inflammation. Curr Neuropharmacol (2016) 0.80

Molecular development of the extrinsic sensory innervation of the gastrointestinal tract. Auton Neurosci (2010) 0.80

Pleiotropic effects of the CB2 cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases. Am J Physiol Heart Circ Physiol (2008) 0.80

Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity. Br J Pharmacol (2015) 0.79

Environment-related adaptive changes of gut commensal microbiota do not alter colonic toll-like receptors but modulate the local expression of sensory-related systems in rats. Microb Ecol (2013) 0.79

Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice. Gut Microbes (2015) 0.79

The Role of the Endocannabinoid System in the Brain-Gut Axis. Gastroenterology (2016) 0.78

In vitro and non-invasive in vivo effects of the cannabinoid-1 receptor agonist AM841 on gastrointestinal motor function in the rat. Neurogastroenterol Motil (2015) 0.77

A CB2-Selective Cannabinoid Suppresses T-Cell Activities and Increases Tregs and IL-10. J Neuroimmune Pharmacol (2015) 0.76

Cannabis Abuse Is Increasing and Associated with Increased Emergency Department Utilization in Gastroenterology Patients. Dig Dis Sci (2016) 0.76

Involvement of Cannabinoid Signaling in Vincristine-Induced Gastrointestinal Dysmotility in the Rat. Front Pharmacol (2017) 0.75

CB2 Cannabinoid Receptor As Potential Target against Alzheimer's Disease. Front Neurosci (2016) 0.75

Therapeutic Use of Cannabis in Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y) (2016) 0.75

The Microbial Hypothesis: Contributions of Adenovirus Infection and Metabolic Endotoxaemia to the Pathogenesis of Obesity. Int J Chronic Dis (2016) 0.75

Cannabinoid Receptor Type 2 (CB2) Dependent and Independent Effects of WIN55,212-2 on Atherosclerosis in Ldlr-null Mice. J Cardiol Ther (2015) 0.75

Metabolism of Anandamide by Human Cytochrome P450 2J2 in the Reconstituted System and Human Intestinal Microsomes. J Pharmacol Exp Ther (2016) 0.75

Evidence for a role of mitogen-activated protein kinases in the treatment of experimental acute pancreatitis. World J Gastroenterol (2014) 0.75

The Impact of CB2 Receptor Ligands on the MK-801-Induced Hyperactivity in Mice. Neurotox Res (2017) 0.75

Articles cited by this

The molecular logic of endocannabinoid signalling. Nat Rev Neurosci (2003) 7.78

Inflammatory bowel disease: cause and immunobiology. Lancet (2007) 6.07

Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (2005) 5.12

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol (2004) 5.12

Inflammation, a key event in cancer development. Mol Cancer Res (2006) 5.03

Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev (2005) 4.08

The endocannabinoid system and its therapeutic exploitation. Nat Rev Drug Discov (2004) 3.47

Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice. Nat Genet (1995) 3.29

Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol (2005) 2.82

Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630. Br J Pharmacol (1999) 2.56

The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest (2004) 2.52

HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor. Proc Natl Acad Sci U S A (1999) 2.32

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. Int J Cancer (2007) 2.29

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med (2006) 2.16

Antifibrogenic role of the cannabinoid receptor CB2 in the liver. Gastroenterology (2005) 2.07

Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol Motil (2007) 1.98

Possible endocannabinoid control of colorectal cancer growth. Gastroenterology (2003) 1.89

Cannabinoids and the gastrointestinal tract. Gut (2001) 1.81

Sensory transmission in the gastrointestinal tract. Neurogastroenterol Motil (2007) 1.71

Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation. Br J Pharmacol (2001) 1.67

Cannabinoid CB2 receptor: a new target for controlling neural cell survival? Trends Pharmacol Sci (2006) 1.66

Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. J Mol Med (Berl) (2007) 1.65

Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice. Gut (2005) 1.63

Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals. Eur J Pharmacol (1997) 1.61

An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. Gastroenterology (2003) 1.60

Enteric neuroplasticity evoked by inflammation. Auton Neurosci (2006) 1.55

Nutrient tasting and signaling mechanisms in the gut. II. The intestine as a sensory organ: neural, endocrine, and immune responses. Am J Physiol (1999) 1.52

Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing. Gastroenterology (2005) 1.47

Endocannabinoids as physiological regulators of colonic propulsion in mice. Gastroenterology (2002) 1.41

Fibrogenesis in Crohn's disease. Am J Gastroenterol (2006) 1.39

Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: prevalence and impact on health. Inflamm Bowel Dis (2006) 1.38

Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. FASEB J (2006) 1.36

Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats. Br J Pharmacol (2004) 1.33

Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. Am J Physiol Gastrointest Liver Physiol (2006) 1.32

The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract. J Mol Med (Berl) (2005) 1.25

The endocannabinoid system and gut-brain signalling. Curr Opin Pharmacol (2007) 1.17

Review article: endocannabinoids and their receptors in the enteric nervous system. Aliment Pharmacol Ther (2005) 1.15

Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in humans: a randomized, placebo-controlled study. Am J Physiol Gastrointest Liver Physiol (2007) 1.14

The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats. Eur J Pharmacol (1999) 1.13

Cannabinoids for gastrointestinal diseases: potential therapeutic applications. Expert Opin Investig Drugs (2003) 1.13

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. Cancer Immunol Immunother (2004) 1.12

Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. Gastroenterology (2007) 1.09

The endocannabinoid system and the molecular basis of paralytic ileus in mice. FASEB J (2002) 1.06

Endocannabinoid overactivity and intestinal inflammation. Gut (2006) 1.06

Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids. Eur J Pharmacol (2003) 1.06

Formation of B and T cell subsets require the cannabinoid receptor CB2. Immunogenetics (2006) 1.05

Cannabinoids and the digestive tract. Handb Exp Pharmacol (2005) 1.04

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2. Gut (2005) 1.00

Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats. Neurogastroenterol Motil (2006) 1.00

Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum. Br J Pharmacol (2000) 0.99

Involvement of cannabinoid receptors in gut motility and visceral perception. Br J Pharmacol (2004) 0.99

Effect of cannabinoids on neural transmission in rat gastric fundus. Can J Physiol Pharmacol (2002) 0.98

Effects on the immune system. Handb Exp Pharmacol (2005) 0.97

Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. Brain Res (1995) 0.97

Cannabinoids cool the intestine. Nat Med (2004) 0.90

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. Gut (2006) 0.89

Targeting the CB2 receptor for immune modulation. Expert Opin Ther Targets (2006) 0.89

Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta. Biochem Biophys Res Commun (2002) 0.89

Activation of the cannabinoid 2 (CB2) receptor inhibits murine mesenteric afferent nerve activity. Neurogastroenterol Motil (2007) 0.80

Articles by these authors

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway. Nat Med (2001) 3.17

Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity. Gastroenterology (1998) 2.46

Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2. J Clin Invest (1996) 2.31

Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology (2001) 2.03

Recurrent aphthous ulcers today: a review of the growing knowledge. Int J Oral Maxillofac Surg (2004) 1.89

Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw. Br J Pharmacol (1999) 1.83

Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia. FASEB J (1997) 1.80

The nucleotide sequence of Saccharomyces cerevisiae chromosome V. Nature (1997) 1.53

Indiscriminate loss of myenteric neurones in the TNBS-inflamed guinea-pig distal colon. Neurogastroenterol Motil (2005) 1.51

Hematogones: a multiparameter analysis of bone marrow precursor cells. Blood (1989) 1.42

Role of Porphyromonas gingivalis protease activity in colonization of oral surfaces. Infect Immun (1996) 1.41

Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice. Gut (1999) 1.35

A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents. Br J Pharmacol (2010) 1.32

Sensory substance P innervation of the stomach and pancreas. Demonstration of capsaicin-sensitive sensory neurons in the rat by combined immunohistochemistry and retrograde tracing. Gastroenterology (1984) 1.29

Genotypic diversity of mutans streptococci in Brazilian nursery children suggests horizontal transmission. J Clin Microbiol (2001) 1.29

Role of Arg-gingipain A in virulence of Porphyromonas gingivalis. Infect Immun (1998) 1.29

MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. Oncogene (2010) 1.25

Interdigitating dendritic cell sarcoma: a rare malignancy responsive to ABVD chemotherapy. Leuk Lymphoma (2002) 1.24

Plasticity of the enteric nervous system during intestinal inflammation. Neurogastroenterol Motil (2005) 1.23

Changes in colonic motility and the electrophysiological properties of myenteric neurons persist following recovery from trinitrobenzene sulfonic acid colitis in the guinea pig. Neurogastroenterol Motil (2007) 1.23

Plasticity of enteric nerve functions in the inflamed and postinflamed gut. Neurogastroenterol Motil (2009) 1.21

Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat. Am J Physiol (1997) 1.19

Serotonin transporter function and expression are reduced in mice with TNBS-induced colitis. Neurogastroenterol Motil (2005) 1.17

Enteric glia. Neurogastroenterol Motil (2004) 1.16

Beneficial effects of local or systemic lidocaine in experimental colitis. Am J Physiol (1994) 1.16

Review article: endocannabinoids and their receptors in the enteric nervous system. Aliment Pharmacol Ther (2005) 1.15

The participation of the sympathetic innervation of the gastrointestinal tract in disease states. Neurogastroenterol Motil (2009) 1.13

Distribution of nitric oxide synthase in rat dorsal vagal complex and effects of microinjection of nitric oxide compounds upon gastric motor function. J Comp Neurol (1997) 1.11

Comparative analysis of Haemophilus influenzae hifA (pilin) genes. Infect Immun (1998) 1.11

Metabolism and binding to cellular macromolecules of a series of hydrocarbons by mouse embryo cells in culture. Int J Cancer (1969) 1.10

An electrophysiological and anatomical study of intestinal afferent fibres in the rat. J Physiol (1988) 1.09

Modulation of ion channels in rod photoreceptors by nitric oxide. Neuron (1994) 1.08

Antineuronal antibodies in idiopathic achalasia and gastro-oesophageal reflux disease. Gut (2003) 1.08

Spontaneously developing chronic colitis in IL-10/iNOS double-deficient mice. Am J Physiol Gastrointest Liver Physiol (2000) 1.07

Aspirin causes rapid up-regulation of cyclo-oxygenase-2 expression in the stomach of rats. Aliment Pharmacol Ther (1997) 1.06

Induction of cyclooxygenase 1 and 2 in the rat stomach during endotoxemia: role in resistance to damage. Gastroenterology (1997) 1.06

Temporal distribution of neuronal and inducible nitric oxide synthase and nitrotyrosine during colitis in rats. Neurogastroenterol Motil (1999) 1.06

Scleroderma. A model for fibrosis. Arch Dermatol (1983) 1.05

Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon. J Auton Nerv Syst (1999) 1.05

Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors. Neurogastroenterol Motil (2009) 1.05

Distribution of calcitonin gene-related peptide, somatostatin, substance P and vasoactive intestinal polypeptide in experimental colitis in rats. Neurogastroenterol Motil (1998) 1.05

Progressive development of a Th1-type hepatic cytokine profile in rats with experimental cholangitis. Hepatology (2000) 1.05

Cytokine imbalance in irritable bowel syndrome: a systematic review and meta-analysis. Neurogastroenterol Motil (2014) 1.03

Functional alterations in jejunal myenteric neurons during inflammation in nematode-infected guinea pigs. Am J Physiol (1998) 1.00

Sensory substance P-innervation of the urinary bladder: possible site of action of capsaicin in causing urine retention in rats. Neuroscience (1983) 0.99

Ulcerative balanoposthitis associated with non-syphilitic spirochaetal infection. Genitourin Med (1986) 0.99

Effects of inflammation on cell proliferation in the myenteric plexus of the guinea-pig ileum. Cell Tissue Res (1997) 0.97

The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice. Neurogastroenterol Motil (2008) 0.96

Interleukin 1 beta-induced increase in substance P in rat myenteric plexus. Gastroenterology (1993) 0.96

Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism. Br J Pharmacol (2013) 0.96

L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans. J Bacteriol (1994) 0.96

The subfornical organ: a central nervous system site for actions of circulating leptin. Am J Physiol Regul Integr Comp Physiol (2008) 0.96

Evidence that L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans. Infect Immun (1994) 0.95

Germ-cell deficient (gcd), an insertional mutation manifested as infertility in transgenic mice. Proc Natl Acad Sci U S A (1991) 0.94

Substance P in the rat parotid gland: evidence for a dual origin from the otic and trigeminal ganglia. Brain Res (1984) 0.94

Regional extraction of circulating norepinephrine, DOPA, and dihydroxyphenylglycol in humans. J Auton Nerv Syst (1991) 0.93

Subsurface defect detection in materials using optical coherence tomography. Opt Express (1998) 0.93

Morphological and immunohistochemical examination of nerves in normal and injured collateral ligaments of rat, rabbit, and human knee joints. Anat Rec (1997) 0.93

The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome. Neurogastroenterol Motil (2008) 0.92

Comparison of pain, motion, and edema after modified radical mastectomy vs. local excision with axillary dissection and radiation. Breast Cancer Res Treat (1992) 0.90

Lung transplant metalloproteinase levels are elevated prior to bronchiolitis obliterans syndrome. Am J Transplant (2007) 0.89

Prevalence of vitamin D inadequacy in Belfast following fragility fracture. Curr Med Res Opin (2006) 0.89

Capsaicin treatment blocks development of hyperkinetic circulation in portal hypertensive and cirrhotic rats. Am J Physiol (1993) 0.89

Disruption of the blood-brain barrier during TNBS colitis. Neurogastroenterol Motil (2005) 0.89

Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. Br J Pharmacol (2012) 0.89

Involvement of L-arginine-nitric oxide pathways in neural relaxation of the sphincter of Oddi. Eur J Pharmacol (1993) 0.88

Cytokine gene polymorphisms are associated with irritable bowel syndrome: a systematic review and meta-analysis. Neurogastroenterol Motil (2012) 0.88

Fos expression in ferret dorsal vagal complex after peripheral emetic stimuli. Am J Physiol (1994) 0.88

Cannabidivarin is anticonvulsant in mouse and rat. Br J Pharmacol (2012) 0.88

Innervation and mast cells of the rat exorbital lacrimal gland: the effects of age. J Auton Nerv Syst (1994) 0.88

Multiple mechanisms contribute to myenteric plexus ablation induced by benzalkonium chloride in the guinea-pig ileum. Cell Tissue Res (1997) 0.87

Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach. Am J Physiol Gastrointest Liver Physiol (2000) 0.87

Multiple colonization defects in a cysteine protease mutant of Porphyromonas gingivalis. J Periodontal Res (1997) 0.87

Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterol Motil (2010) 0.87

Role of 5-HT in cholera toxin-induced mucin secretion in the rat small intestine. Am J Physiol (1996) 0.86

Substance P levels in experimental ileitis in guinea pigs: effects of misoprostol. Am J Physiol (1993) 0.86

Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation. Br J Pharmacol (2013) 0.85

Ionizing radiation reduces neurally evoked electrolyte transport in rat ileum through a mast cell-dependent mechanism. Gastroenterology (1994) 0.85

Extrinsic innervation of the rat pancreas: demonstration of vagal sensory neurones in the rat by retrograde tracing. Neurosci Lett (1983) 0.84

The effects of glucagon-like peptide 2 on enteric neurons in intestinal inflammation. Neurogastroenterol Motil (2010) 0.84

Emergency services and the elderly: the role of the social worker. Health Soc Work (1982) 0.84

The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity. Nutr Diabetes (2013) 0.84

The angiogenic potential of three-dimensional open porous synthetic matrix materials. Biomaterials (2007) 0.83

Arrested larval development in cattle nematodes. Parasitol Today (1987) 0.83

Adaptation of intestinal secretomotor function and nutrient absorption in response to diet-induced obesity. Neurogastroenterol Motil (2010) 0.83

Evidence for CGRP accumulation and activity in experimental neuromas. Am J Physiol (1995) 0.83

Accumulation and degranulation of mast cells in experimental neuromas. Neurosci Lett (1994) 0.83

A broader vision for managed care, Part 2: A typology of community benefits. Health Aff (Millwood) (1998) 0.83

Oral EBV and KSHV infection in HIV. Adv Dent Res (2006) 0.83

The relationship between inflammation-induced neuronal excitability and disrupted motor activity in the guinea pig distal colon. Neurogastroenterol Motil (2011) 0.83

Expression, activity and cellular localization of inducible nitric oxide synthase in rat ileum and colon post-irradiation. Int J Radiat Biol (1998) 0.82

Nutritional status and food intake in human immunodeficiency virus infection. GI/HIV Study Group. J Acquir Immune Defic Syndr (1992) 0.82

Impaired vasodilatory responses in the gastric microcirculation of anesthetized rats with secondary biliary cirrhosis. Gastroenterology (1995) 0.82

The use of constitutive nuclear oncoproteins to count neurons in the enteric nervous system of the guinea pig. Cell Tissue Res (1994) 0.82

Intracisternal TRH analog induces Fos expression in gastric myenteric neurons and glia in conscious rats. Am J Physiol Gastrointest Liver Physiol (2001) 0.82

Evidence for a role of capsaicin-sensitive mucosal afferent nerves in the regulation of mesenteric blood flow in the dog. Gastroenterology (1986) 0.82

A novel receptor for calcitonin gene-related peptide (CGRP) mediates secretion in the rat colon: implications for secretory function in colitis. FASEB J (2000) 0.82

The expression and role of Fas ligand in intestinal inflammation. Neurogastroenterol Motil (2004) 0.82

Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterol Motil (2012) 0.82