Published in Clin Cancer Res on October 01, 2007
Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells. Oncogene (2008) 1.08
p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis. Cancer Metastasis Rev (2010) 0.99
A novel role of Shc adaptor proteins in steroid hormone-regulated cancers. Endocr Relat Cancer (2008) 0.88
Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells. Free Radic Biol Med (2012) 0.88
Elevated preoperative carcinoembryonic antigen (CEA) and Ki67 is predictor of decreased survival in IIA stage colon cancer. World J Surg (2013) 0.86
P66shc and its downstream Eps8 and Rac1 proteins are upregulated in esophageal cancers. Cell Commun Signal (2010) 0.83
Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination. PLoS One (2011) 0.82
The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells. J Biol Chem (2014) 0.82
p66Shc as a switch in bringing about contrasting responses in cell growth: implications on cell proliferation and apoptosis. Mol Cancer (2015) 0.79
Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells. Br J Cancer (2014) 0.78
p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition. Mol Cell Biol (2014) 0.77
The G protein-coupled estrogen receptor-1, GPER-1, promotes fibrillogenesis via a Shc-dependent pathway resulting in anchorage-independent growth. Horm Cancer (2014) 0.75
p66Shc longevity protein regulates the proliferation of human ovarian cancer cells. Mol Carcinog (2014) 0.75
The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway. Int J Clin Exp Pathol (2015) 0.75
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet (2010) 3.99
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (2012) 3.74
Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge. J Invest Dermatol (2003) 3.72
Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol (2002) 3.65
TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nat Genet (2011) 3.06
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch. Nat Neurosci (2011) 3.05
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest. FEBS Lett (2008) 2.85
Stress induces tRNA cleavage by angiogenin in mammalian cells. FEBS Lett (2008) 2.66
Average energy intake among pregnant women carrying a boy compared with a girl. BMJ (2003) 2.55
Reasons for increasing trends in large for gestational age births. Obstet Gynecol (2004) 2.54
A subpopulation of nociceptors specifically linked to itch. Nat Neurosci (2012) 2.41
Transient increase in breast cancer risk after giving birth: postpartum period with the highest risk (Sweden). Cancer Causes Control (2002) 2.39
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol (2008) 2.39
Use of p63 expression in distinguishing primary and metastatic cutaneous adnexal neoplasms from metastatic adenocarcinoma to skin. J Cutan Pathol (2007) 2.14
The TMPRSS2:ERG rearrangement, ERG expression, and prostate cancer outcomes: a cohort study and meta-analysis. Cancer Epidemiol Biomarkers Prev (2012) 2.13
Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin Cancer Res (2006) 2.07
Phenotype of microsatellite unstable colorectal carcinomas: Well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instability. Am J Surg Pathol (2003) 1.97
RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease. Acta Neuropathol (2006) 1.94
Bile Acid secreted by male sea lamprey that acts as a sex pheromone. Science (2002) 1.89
Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivo. Cancer Res (2003) 1.88
IMP3 predicts aggressive superficial urothelial carcinoma of the bladder. Clin Cancer Res (2008) 1.87
NMNAT1 mutations cause Leber congenital amaurosis. Nat Genet (2012) 1.86
Hemodynamics instability score in chronic fatigue syndrome and in non-chronic fatigue syndrome. Semin Arthritis Rheum (2002) 1.82
Full-field implementation of a perfect eavesdropper on a quantum cryptography system. Nat Commun (2011) 1.80
p63 and TTF-1 immunostaining. A useful marker panel for distinguishing small cell carcinoma of lung from poorly differentiated squamous cell carcinoma of lung. Am J Clin Pathol (2003) 1.79
Experimentally faking the violation of Bell's inequalities. Phys Rev Lett (2011) 1.74
Fear of injections in young adults: prevalence and associations. Am J Trop Med Hyg (2003) 1.73
Comparison of thyroid transcription factor-1 expression by 2 monoclonal antibodies in pulmonary and nonpulmonary primary tumors. Appl Immunohistochem Mol Morphol (2010) 1.71
Human hair growth deficiency is linked to a genetic defect in the phospholipase gene LIPH. Science (2006) 1.71
The NLRP12 inflammasome recognizes Yersinia pestis. Immunity (2012) 1.70
Semaphorin-3F is an inhibitor of tumor angiogenesis. Cancer Res (2004) 1.70
Low-dose total body irradiation followed by allogeneic lymphocyte infusion may induce remission in patients with refractory hematologic malignancy. Blood (2002) 1.70
A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination. J Immunol (2011) 1.68
Epidermal growth factor receptor, c-MET, beta-catenin, and p53 expression as prognostic indicators in stage II colon cancer: a tissue microarray study. Clin Cancer Res (2004) 1.66
Identification of disease-causing mutations in autosomal dominant retinitis pigmentosa (adRP) using next-generation DNA sequencing. Invest Ophthalmol Vis Sci (2011) 1.63
Quiescent, slow-cycling stem cell populations in cancer: a review of the evidence and discussion of significance. J Oncol (2010) 1.63
Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study. Lancet Oncol (2006) 1.61
VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc Natl Acad Sci U S A (2011) 1.60
Birthweight differences between USA and China and their relevance to breast cancer aetiology. Int J Epidemiol (2003) 1.59
Intratumoral CD8+ T lymphocytes as a prognostic factor of survival in endometrial carcinoma. Clin Cancer Res (2004) 1.55
Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens in serous ovarian neoplasms. Clin Cancer Res (2003) 1.54
Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am J Pathol (2004) 1.52
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell (2008) 1.52
Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease. Hum Pathol (2007) 1.52
Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2. Cancer Discov (2013) 1.52
Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene. Proc Natl Acad Sci U S A (2002) 1.51
Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study. Mod Pathol (2005) 1.50
Identification of interleukin-6 promoter polymorphisms in the Chinese Han population and their functional significance. Crit Care Med (2008) 1.49
Immune history shapes specificity of pandemic H1N1 influenza antibody responses. J Exp Med (2013) 1.47
Targeting retroviral Zn finger-DNA interactions: a small-molecule approach using the electrophilic nature of trans-platinum-nucleobase compounds. Chem Biol (2006) 1.47
Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology (2010) 1.46
A functional Notch-survivin gene signature in basal breast cancer. Breast Cancer Res (2008) 1.46
Fractal analysis and recurrence quantification analysis of heart rate and pulse transit time for diagnosing chronic fatigue syndrome. Clin Auton Res (2002) 1.45
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. PLoS One (2009) 1.44
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. J Clin Invest (2012) 1.44
Concurrent MEK2 mutation and BRAF amplification confer resistance to BRAF and MEK inhibitors in melanoma. Cell Rep (2013) 1.43
Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med (2006) 1.40
MicroRNA-101 targets MAPK phosphatase-1 to regulate the activation of MAPKs in macrophages. J Immunol (2010) 1.38
Expression of uncoupling protein-2 in human colon cancer. Clin Cancer Res (2004) 1.37
Claudin expression in gastric adenocarcinomas: a tissue microarray study with prognostic correlation. Hum Pathol (2005) 1.36
Correlation of umbilical cord blood hormones and growth factors with stem cell potential: implications for the prenatal origin of breast cancer hypothesis. Breast Cancer Res (2007) 1.35
A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth. Blood (2003) 1.34
Human CD19(+)CD25(high) B regulatory cells suppress proliferation of CD4(+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells. Autoimmun Rev (2011) 1.33
Plasma volume expansion in pregnancy: implications for biomarkers in population studies. Cancer Epidemiol Biomarkers Prev (2007) 1.32
Combination of quantitative IMP3 and tumor stage: a new system to predict metastasis for patients with localized renal cell carcinomas. Clin Cancer Res (2008) 1.31
Treatment seeking for symptoms suggestive of TB: comparison between migrants and permanent urban residents in Chongqing, China. Trop Med Int Health (2008) 1.29
Early life events and conditions and breast cancer risk: from epidemiology to etiology. Int J Cancer (2008) 1.28
Heparanase localization and expression by head and neck cancer: correlation with tumor progression and patient survival. Neoplasia (2006) 1.28
Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice. Food Chem Toxicol (2007) 1.26
The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Sci Signal (2013) 1.25
Pregnancy estriol, estradiol, progesterone and prolactin in relation to birth weight and other birth size variables (United States). Cancer Causes Control (2003) 1.22
Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (2008) 1.22
Decreased expression of gastrokine 1 and the trefoil factor interacting protein TFIZ1/GKN2 in gastric cancer: influence of tumor histology and relationship to prognosis. Clin Cancer Res (2008) 1.22
Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcome. Clin Cancer Res (2008) 1.22
Association of fetal hormone levels with stem cell potential: evidence for early life roots of human cancer. Cancer Res (2005) 1.21
Pregnancy hormone concentrations across ethnic groups: implications for later cancer risk. Cancer Epidemiol Biomarkers Prev (2005) 1.21
Mas-related G-protein-coupled receptors inhibit pathological pain in mice. Proc Natl Acad Sci U S A (2010) 1.20
Role of HTLV-1 proviral DNA load and clonality in the development of adult T-cell leukemia/lymphoma in asymptomatic carriers. Int J Cancer (2004) 1.19
Prevalence of eye diseases and causes of visual impairment in school-aged children in Western China. J Epidemiol (2011) 1.17
Disruption of interleukin-1 signaling improves the quality of wound healing. Am J Pathol (2009) 1.17
Phase II safety and clinical comparison with single-photon emission computed tomography myocardial perfusion imaging for detection of coronary artery disease: flurpiridaz F 18 positron emission tomography. J Am Coll Cardiol (2012) 1.16
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step. EMBO J (2013) 1.14
Nausea and vomiting in pregnancy in relation to prolactin, estrogens, and progesterone: a prospective study. Obstet Gynecol (2003) 1.14
IMP3, a new biomarker to predict progression of cervical intraepithelial neoplasia into invasive cancer. Am J Surg Pathol (2011) 1.13
Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Dev Biol (2011) 1.13
Increasing incidence of pregnancy-associated breast cancer in Sweden. Obstet Gynecol (2009) 1.13
Edwardsiella comparative phylogenomics reveal the new intra/inter-species taxonomic relationships, virulence evolution and niche adaptation mechanisms. PLoS One (2012) 1.13
Increased mortality in women with breast cancer detected during pregnancy and different periods postpartum. Cancer Epidemiol Biomarkers Prev (2011) 1.12