PubRank

James L Riley

Author PubWeight™ 141.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 2008 14.75
2 Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther 2009 6.91
3 The CD28 signaling pathway regulates glucose metabolism. Immunity 2002 6.65
4 CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol Cell Biol 2005 6.18
5 Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proc Natl Acad Sci U S A 2009 5.36
6 Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 2002 5.10
7 SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol 2004 4.58
8 Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nat Biotechnol 2002 3.43
9 FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci U S A 2007 3.32
10 Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Sci Transl Med 2012 3.29
11 DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells. Virology 2003 3.20
12 Engineering lymphocyte subsets: tools, trials and tribulations. Nat Rev Immunol 2009 3.06
13 Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Mol Ther 2007 2.99
14 Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. Nat Med 2008 2.64
15 Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity 2011 2.49
16 The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Sci Transl Med 2010 2.40
17 CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients. Sci Transl Med 2012 2.22
18 Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci Transl Med 2011 2.14
19 Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection. J Virol 2003 2.11
20 CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes. J Immunol 2003 2.09
21 Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci Transl Med 2013 2.07
22 The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. Sci Transl Med 2011 2.04
23 CD28 costimulation is essential for human T regulatory expansion and function. J Immunol 2008 1.86
24 Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection. Blood 2013 1.80
25 Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells. Blood 2008 1.80
26 Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J 2004 1.79
27 Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. J Immunol 2008 1.71
28 TCR affinity and specificity requirements for human regulatory T-cell function. Blood 2012 1.69
29 Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor. Clin Cancer Res 2011 1.53
30 Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases. PLoS Pathog 2011 1.50
31 Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol 2011 1.49
32 Combination checkpoint blockade--taking melanoma immunotherapy to the next level. N Engl J Med 2013 1.45
33 Strength of PD-1 signaling differentially affects T-cell effector functions. Proc Natl Acad Sci U S A 2013 1.42
34 FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int Immunol 2007 1.39
35 Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. PLoS One 2011 1.39
36 Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1. PLoS Biol 2010 1.35
37 cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. J Clin Invest 2006 1.35
38 Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells. J Virol 2007 1.31
39 Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs. Clin Immunol 2010 1.30
40 Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein. PLoS Pathog 2010 1.29
41 Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha. J Virol 2008 1.28
42 A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes. Clin Immunol 2002 1.26
43 Clinical perspectives for regulatory T cells in transplantation tolerance. Semin Immunol 2011 1.23
44 B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs. J Immunol 2006 1.19
45 Umbilical cord blood xenografts in immunodeficient mice reveal that T cells enhance hematopoietic engraftment beyond overcoming immune barriers by stimulating stem cell differentiation. Biol Blood Marrow Transplant 2007 1.18
46 Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res 2006 1.15
47 The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol Cell 2008 1.15
48 Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5. Hum Gene Ther 2013 1.14
49 RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood 2007 1.13
50 Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes. J Transl Med 2011 1.10
51 Signalling to suit function: tailoring phosphoinositide 3-kinase during T-cell activation. Trends Immunol 2007 1.09
52 TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients. Clin Cancer Res 2003 1.07
53 Genetic engineering of T cells for adoptive immunotherapy. Immunol Res 2008 1.05
54 Adoptive immunotherapy: good habits instilled at youth have long-term benefits. Immunol Res 2008 1.02
55 Extensive replicative capacity of human central memory T cells. J Immunol 2004 1.02
56 HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells. Clin Immunol 2003 0.99
57 Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells. J Immunol 2005 0.96
58 Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells. PLoS One 2008 0.94
59 Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation. Proc Natl Acad Sci U S A 2002 0.92
60 HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse model. Mol Ther 2010 0.88
61 Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner. J Immunol 2014 0.85
62 Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28. J Immunol 2013 0.84
63 Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest 2016 0.83
64 The battle over mTOR: an emerging theatre in host-pathogen immunity. PLoS Pathog 2012 0.81
65 Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection. J Immunol 2012 0.81
66 Topoisomerase inhibitors modulate expression of melanocytic antigens and enhance T cell recognition of tumor cells. Cancer Immunol Immunother 2010 0.80
67 The potent oncogene NPM-ALK mediates malignant transformation of normal human CD4(+) T lymphocytes. Am J Pathol 2013 0.80
68 The human CD8β M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties. PLoS One 2013 0.75