Published in Physiol Rev on October 01, 2007
The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol (2009) 2.80
Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation (2010) 2.37
Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics. Nat Commun (2012) 2.23
Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling. Cardiovasc Res (2008) 2.22
Matricellular proteins in cardiac adaptation and disease. Physiol Rev (2012) 2.01
The pathogenesis of cardiac fibrosis. Cell Mol Life Sci (2013) 1.96
Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunol (2008) 1.79
CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. Am J Pathol (2010) 1.69
Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease. Fibrogenesis Tissue Repair (2012) 1.65
The extracellular matrix: at the center of it all. J Mol Cell Cardiol (2009) 1.64
Secreted Frizzled-related protein 2 as a target in antifibrotic therapeutic intervention. Am J Physiol Cell Physiol (2013) 1.62
Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload. Circulation (2015) 1.55
Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation (2013) 1.48
Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing. Circulation (2008) 1.45
Retracted Cardioprotective activity of placental growth factor in a rat model of acute myocardial infarction: nanoparticle-based delivery versus direct myocardial injection. BMC Cardiovasc Disord (2014) 1.44
Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing. Am J Physiol Heart Circ Physiol (2009) 1.41
Moving from static to dynamic complexity in hydrogel design. Nat Commun (2012) 1.40
Cardiac aging: from molecular mechanisms to significance in human health and disease. Antioxid Redox Signal (2012) 1.40
Temporal and spatial expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases following myocardial infarction. Cardiovasc Ther (2010) 1.39
Protease-activated drug development. Theranostics (2012) 1.36
Membrane-associated matrix proteolysis and heart failure. Circ Res (2013) 1.35
Extracellular matrix remodeling during the progression of volume overload-induced heart failure. J Mol Cell Cardiol (2009) 1.32
Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circ Res (2009) 1.32
Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases. Pathol Int (2010) 1.29
Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic. Circ Res (2011) 1.25
The history of matrix metalloproteinases: milestones, myths, and misperceptions. Am J Physiol Heart Circ Physiol (2012) 1.22
Rapid quantification of myocardial fibrosis: a new macro-based automated analysis. Cell Oncol (Dordr) (2011) 1.22
Akt1 is necessary for the vascular maturation and angiogenesis during cutaneous wound healing. Angiogenesis (2008) 1.20
Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure. Circ Heart Fail (2011) 1.19
Periostin as a heterofunctional regulator of cardiac development and disease. Curr Genomics (2008) 1.16
Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol (2011) 1.14
Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism. PLoS One (2010) 1.13
Osteopontin: role in extracellular matrix deposition and myocardial remodeling post-MI. J Mol Cell Cardiol (2009) 1.11
Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in Timp3-deficient heart. J Biol Chem (2009) 1.10
Quantitative N-linked glycoproteomics of myocardial ischemia and reperfusion injury reveals early remodeling in the extracellular environment. Mol Cell Proteomics (2011) 1.09
Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling. PLoS One (2009) 1.08
Local hydrogel release of recombinant TIMP-3 attenuates adverse left ventricular remodeling after experimental myocardial infarction. Sci Transl Med (2014) 1.08
Multimodality imaging of myocardial injury and remodeling. J Nucl Med (2010) 1.08
Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation. Am J Pathol (2009) 1.07
Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis. Am J Physiol Heart Circ Physiol (2012) 1.06
Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. J Mol Cell Cardiol (2009) 1.06
The endothelial glycocalyx as a barrier to leukocyte adhesion and its mediation by extracellular proteases. Ann Biomed Eng (2011) 1.06
Fibrosis and heart failure. Heart Fail Rev (2014) 1.05
Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function. J Appl Physiol (1985) (2012) 1.05
Matrix metalloproteases and PAR1 activation. Blood (2012) 1.05
Cardiac fibroblast in development and wound healing. J Mol Cell Cardiol (2014) 1.05
Matrix metalloproteinase activation predicts amelioration of remodeling after dietary modification in injured arteries. Arterioscler Thromb Vasc Biol (2010) 1.04
The fibrosis-cell death axis in heart failure. Heart Fail Rev (2016) 1.04
Chemokines and cardiac fibrosis. Front Biosci (Schol Ed) (2009) 1.03
Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure. Hypertension (2014) 1.03
Coordinated modular functionality and prognostic potential of a heart failure biomarker-driven interaction network. BMC Syst Biol (2010) 1.03
Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload. J Mol Cell Cardiol (2010) 1.02
Scavenging superoxide selectively in mouse forebrain is associated with improved cardiac function and survival following myocardial infarction. Am J Physiol Regul Integr Comp Physiol (2008) 1.02
MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin. J Cell Sci (2011) 1.02
'Integrative Physiology 2.0': integration of systems biology into physiology and its application to cardiovascular homeostasis. J Physiol (2011) 1.01
Tissue inhibitor of metalloproteinases (TIMPs) in heart failure. Heart Fail Rev (2012) 1.01
Inhibition of matrix metalloproteinases improves left ventricular function in mice lacking osteopontin after myocardial infarction. Mol Cell Biochem (2008) 1.00
SPARC regulates collagen interaction with cardiac fibroblast cell surfaces. Am J Physiol Heart Circ Physiol (2011) 1.00
Integrating the myocardial matrix into heart failure recognition and management. Circ Res (2013) 1.00
Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium. J Mol Cell Cardiol (2009) 0.99
Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. Am J Pathol (2009) 0.98
Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. Am J Physiol Heart Circ Physiol (2010) 0.98
β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells. Circulation (2012) 0.97
Myocardial remodeling: cellular and extracellular events and targets. Annu Rev Physiol (2011) 0.97
Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging. Circ Heart Fail (2009) 0.97
Dynamic changes in matrix metalloprotienase activity within the human myocardial interstitium during myocardial arrest and reperfusion. Circulation (2008) 0.97
Targeting matrix metalloproteinases in heart disease: lessons from endogenous inhibitors. Biochem Pharmacol (2014) 0.95
Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target. Heart Fail Rev (2014) 0.95
Role of various proteases in cardiac remodeling and progression of heart failure. Heart Fail Rev (2012) 0.95
The impacts of age and frailty on heart rate and sinoatrial node function. J Physiol (2016) 0.95
Inhibition of matrix metalloproteinase-2 by PARP inhibitors. Biochem Biophys Res Commun (2009) 0.95
Complex temporal regulation of capillary morphogenesis by fibroblasts. Am J Physiol Cell Physiol (2010) 0.95
Recapitulation of the embryonic cardiovascular progenitor cell niche. Biomaterials (2011) 0.95
Ventricular remodeling and function: insights using murine echocardiography. J Mol Cell Cardiol (2009) 0.95
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure. PLoS One (2013) 0.94
17beta-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts. Cardiovasc Res (2009) 0.94
Extracellular matrix and fibroblast communication following myocardial infarction. J Cardiovasc Transl Res (2012) 0.93
Thrombospondins in the heart: potential functions in cardiac remodeling. J Cell Commun Signal (2009) 0.93
Role of osteopontin in heart failure associated with aging. Heart Fail Rev (2010) 0.93
Phosphatase PTEN is critically involved in post-myocardial infarction remodeling through the Akt/interleukin-10 signaling pathway. Basic Res Cardiol (2012) 0.92
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity. PLoS One (2012) 0.92
Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype. J Cardiovasc Electrophysiol (2010) 0.92
Ischemia induced peroxynitrite dependent modifications of cardiomyocyte MLC1 increases its degradation by MMP-2 leading to contractile dysfunction. J Cell Mol Med (2010) 0.91
Pleiotropic effects of neutrophils on myocyte apoptosis and left ventricular remodeling during early volume overload. J Mol Cell Cardiol (2009) 0.91
Treatment with N-acetyl-seryl-aspartyl-lysyl-proline prevents experimental autoimmune myocarditis in rats. Am J Physiol Heart Circ Physiol (2012) 0.91
Myocardial fibroblast-matrix interactions and potential therapeutic targets. J Mol Cell Cardiol (2014) 0.91
Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice. Am J Physiol Heart Circ Physiol (2008) 0.91
Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J (2013) 0.91
Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling. J Mol Cell Cardiol (2015) 0.91
Recurrent exposure to subclinical lipopolysaccharide increases mortality and induces cardiac fibrosis in mice. PLoS One (2013) 0.90
Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats. Am J Physiol Heart Circ Physiol (2011) 0.90
Progress in material design for biomedical applications. Proc Natl Acad Sci U S A (2015) 0.90
MT1-MMP-dependent remodeling of cardiac extracellular matrix structure and function following myocardial infarction. Am J Pathol (2012) 0.89
Pharmacological postconditioning with sevoflurane after cardiopulmonary resuscitation reduces myocardial dysfunction. Crit Care (2011) 0.89
Cardiovascular magnetic resonance characterization of peri-infarct zone remodeling following myocardial infarction. J Cardiovasc Magn Reson (2012) 0.89
Myocardial fibrosis induced by exposure to subclinical lipopolysaccharide is associated with decreased miR-29c and enhanced NOX2 expression in mice. PLoS One (2014) 0.89
New insights into mechanisms of cardioprotection mediated by thyroid hormones. J Thyroid Res (2013) 0.88
Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition. Circ Heart Fail (2008) 0.88
Substance P induces adverse myocardial remodelling via a mechanism involving cardiac mast cells. Cardiovasc Res (2011) 0.88