1
|
EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.
|
Cancer Cell
|
2009
|
3.40
|
2
|
Neuregulin-1 enhances depolarization-induced GABA release.
|
Neuron
|
2007
|
2.89
|
3
|
Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer.
|
Clin Cancer Res
|
2009
|
2.13
|
4
|
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells.
|
J Biol Chem
|
2006
|
1.99
|
5
|
Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101).
|
J Biol Chem
|
2004
|
1.85
|
6
|
VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.
|
EMBO J
|
2005
|
1.63
|
7
|
Time-varying pattern of recurrence risk for Chinese breast cancer patients.
|
Breast Cancer Res Treat
|
2008
|
1.57
|
8
|
Breast cancer in a transitional society over 18 years: trends and present status in Shanghai, China.
|
Breast Cancer Res Treat
|
2009
|
1.49
|
9
|
Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1.
|
Mol Cell Biol
|
2002
|
1.49
|
10
|
Breast cancer subpopulation with high risk of internal mammary lymph nodes metastasis: analysis of 2,269 Chinese breast cancer patients treated with extended radical mastectomy.
|
Breast Cancer Res Treat
|
2007
|
1.49
|
11
|
Regulation and localization of CAS substrate domain tyrosine phosphorylation.
|
Cell Signal
|
2004
|
1.47
|
12
|
Etk/Bmx transactivates vascular endothelial growth factor 2 and recruits phosphatidylinositol 3-kinase to mediate the tumor necrosis factor-induced angiogenic pathway.
|
J Biol Chem
|
2003
|
1.46
|
13
|
Clinicopathological features of the triple-negative tumors in Chinese breast cancer patients.
|
Breast Cancer Res Treat
|
2008
|
1.40
|
14
|
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
|
Proteomics
|
2006
|
1.32
|
15
|
Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer.
|
Breast Cancer Res
|
2007
|
1.29
|
16
|
Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity.
|
J Biol Chem
|
2006
|
1.27
|
17
|
The prevalence of PALB2 germline mutations in BRCA1/BRCA2 negative Chinese women with early onset breast cancer or affected relatives.
|
Breast Cancer Res Treat
|
2008
|
1.23
|
18
|
Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats.
|
J Endocrinol
|
2009
|
1.20
|
19
|
Development and trends of surgical modalities for breast cancer in China: a review of 16-year data.
|
Ann Surg Oncol
|
2007
|
1.19
|
20
|
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
|
Breast Cancer Res Treat
|
2004
|
1.18
|
21
|
Gene expression profile analysis of an isogenic tumour metastasis model reveals a functional role for oncogene AF1Q in breast cancer metastasis.
|
Eur J Cancer
|
2006
|
1.16
|
22
|
ERbeta exerts multiple stimulative effects on human breast carcinoma cells.
|
Oncogene
|
2004
|
1.12
|
23
|
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor.
|
J Cancer Res Clin Oncol
|
2008
|
1.11
|
24
|
The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified.
|
Breast Cancer Res Treat
|
2007
|
1.10
|
25
|
UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.
|
Breast Cancer Res Treat
|
2009
|
1.06
|
26
|
PA-MSHA inhibits proliferation and induces apoptosis through the up-regulation and activation of caspases in the human breast cancer cell lines.
|
J Cell Biochem
|
2009
|
1.05
|
27
|
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer.
|
Clin Cancer Res
|
2013
|
1.05
|
28
|
Molecular subtype approximated by quantitative estrogen receptor, progesterone receptor and Her2 can predict the prognosis of breast cancer.
|
Tumori
|
2010
|
1.03
|
29
|
Identification of the functional role of AF1Q in the progression of breast cancer.
|
Breast Cancer Res Treat
|
2007
|
1.00
|
30
|
Progesterone receptor status provides predictive value for adjuvant endocrine therapy in older estrogen receptor-positive breast cancer patients.
|
Breast
|
2007
|
1.00
|
31
|
The prevalence of BRCA1 and BRCA2 mutations in eastern Chinese women with breast cancer.
|
J Cancer Res Clin Oncol
|
2006
|
1.00
|
32
|
Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53.
|
Hum Mol Genet
|
2009
|
0.98
|
33
|
Hazard of breast cancer-specific mortality among women with estrogen receptor-positive breast cancer after five years from diagnosis: implication for extended endocrine therapy.
|
J Clin Endocrinol Metab
|
2012
|
0.97
|
34
|
TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade.
|
FEBS Lett
|
2007
|
0.97
|
35
|
Estrogen receptor-related genes as an important panel of predictors for breast cancer response to neoadjuvant chemotherapy.
|
Cancer Lett
|
2011
|
0.97
|
36
|
Site-specific relapse pattern of the triple negative tumors in Chinese breast cancer patients.
|
BMC Cancer
|
2009
|
0.96
|
37
|
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer.
|
PLoS One
|
2012
|
0.96
|
38
|
Outcome of pure mucinous breast carcinoma compared to infiltrating ductal carcinoma: a population-based study from China.
|
Ann Surg Oncol
|
2012
|
0.96
|
39
|
A functional polymorphism in the promoter region of GSTM1 implies a complex role for GSTM1 in breast cancer.
|
FASEB J
|
2009
|
0.96
|
40
|
Different distribution of breast cancer subtypes in breast ductal carcinoma in situ (DCIS), DCIS with microinvasion, and DCIS with invasion component.
|
Ann Surg Oncol
|
2010
|
0.95
|
41
|
Molecular subtype can predict the response and outcome of Chinese locally advanced breast cancer patients treated with preoperative therapy.
|
Oncol Rep
|
2010
|
0.94
|
42
|
USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO.
|
EMBO J
|
2013
|
0.93
|
43
|
DNA bending by bZIP charge variants: a unified study using electrophoretic phasing and fluorescence resonance energy transfer.
|
Biochemistry
|
2002
|
0.93
|
44
|
Identification of serum biomarkers for pancreatic adenocarcinoma by proteomic analysis.
|
Cancer Sci
|
2009
|
0.93
|
45
|
Triple-negative breast cancer types exhibit a distinct poor clinical characteristic in lymph node-negative Chinese patients.
|
Oncol Rep
|
2008
|
0.92
|
46
|
Mutation analysis of BRIP1/BACH1 in BRCA1/BRCA2 negative Chinese women with early onset breast cancer or affected relatives.
|
Breast Cancer Res Treat
|
2008
|
0.92
|
47
|
Biomarker alterations with metronomic use of low-dose zoledronic acid for breast cancer patients with bone metastases and potential clinical significance.
|
Breast Cancer Res Treat
|
2010
|
0.91
|
48
|
Evaluating the performance of models for predicting the BRCA germline mutations in Han Chinese familial breast cancer patients.
|
Breast Cancer Res Treat
|
2008
|
0.91
|
49
|
Breast cancer patients with estrogen receptor-negative/progesterone receptor-positive tumors: being younger and getting less benefit from adjuvant tamoxifen treatment.
|
J Cancer Res Clin Oncol
|
2008
|
0.90
|
50
|
Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.
|
Breast Cancer Res Treat
|
2009
|
0.90
|
51
|
Management strategy of early-stage breast cancer patients with a positive sentinel lymph node: With or without axillary lymph node dissection.
|
Crit Rev Oncol Hematol
|
2010
|
0.90
|
52
|
Effect of large tumor size on cancer-specific mortality in node-negative breast cancer.
|
Mayo Clin Proc
|
2012
|
0.89
|
53
|
A straightforward but not piecewise relationship between age and lymph node status in Chinese breast cancer patients.
|
PLoS One
|
2010
|
0.89
|
54
|
Dominant-negative E-cadherin inhibits the invasiveness of inflammatory breast cancer cells in vitro.
|
J Cancer Res Clin Oncol
|
2006
|
0.88
|
55
|
TIEG1 inhibits breast cancer invasion and metastasis by inhibition of epidermal growth factor receptor (EGFR) transcription and the EGFR signaling pathway.
|
Mol Cell Biol
|
2011
|
0.88
|
56
|
The analysis of BRCA1 mutations in eastern Chinese patients with early onset breast cancer and affected relatives.
|
Hum Mutat
|
2003
|
0.88
|
57
|
Epidural Combined with General Anesthesia versus General Anesthesia Alone in Patients Undergoing Free Flap Breast Reconstruction.
|
Plast Reconstr Surg
|
2016
|
0.87
|
58
|
Fiberoptic ductoscopy combined with cytology testing in the patients of spontaneous nipple discharge.
|
Breast Cancer Res Treat
|
2007
|
0.87
|
59
|
Cisplatin and gemcitabine as the first line therapy in metastatic triple negative breast cancer.
|
Int J Cancer
|
2014
|
0.86
|
60
|
Breast cancer in Chinese elderly women: pathological and clinical characteristics and factors influencing treatment patterns.
|
Crit Rev Oncol Hematol
|
2009
|
0.86
|
61
|
Weekly paclitaxel/carboplatin/trastuzumab therapy improves pathologic complete remission in aggressive HER2-positive breast cancers, especially in luminal-B subtype, compared with a once-every-3-weeks schedule.
|
Oncologist
|
2013
|
0.85
|
62
|
Models for predicting BRCA1 and BRCA2 mutations in Han Chinese familial breast and/or ovarian cancer patients.
|
Breast Cancer Res Treat
|
2008
|
0.84
|
63
|
Comparative study of one-step nucleic acid amplification assay, frozen section, and touch imprint cytology for intraoperative assessment of breast sentinel lymph node in Chinese patients.
|
Cancer Sci
|
2012
|
0.84
|
64
|
Free Flap Monitoring Using Near-Infrared Spectroscopy: A Systemic Review.
|
Ann Plast Surg
|
2016
|
0.83
|
65
|
Morphine induces desensitization of insulin receptor signaling.
|
Mol Cell Biol
|
2003
|
0.83
|
66
|
Basal cytokeratin expression in relation to immunohistochemical and clinical characterization in breast cancer patients with triple negative phenotype.
|
Tumori
|
2009
|
0.83
|
67
|
Tumor characteristics and the clinical outcome of invasive lobular carcinoma compared to infiltrating ductal carcinoma in a Chinese population.
|
World J Surg Oncol
|
2012
|
0.82
|
68
|
Are changes in circulating tumor cell (CTC) count associated with the response to neoadjuvant chemotherapy in local advanced breast cancer? A meta-analysis.
|
Oncol Res Treat
|
2014
|
0.81
|
69
|
Retrospective analysis of 119 Chinese noninflammatory locally advanced breast cancer cases treated with intravenous combination of vinorelbine and epirubicin as a neoadjuvant chemotherapy: a median follow-up of 63.4 months.
|
BMC Cancer
|
2009
|
0.81
|
70
|
[Sentinel lymph node biopsy in breast cancer].
|
Zhonghua Wai Ke Za Zhi
|
2002
|
0.81
|
71
|
Lymph node counts and ratio in axillary dissections following neoadjuvant chemotherapy for breast cancer: a better alternative to traditional pN staging.
|
Ann Surg Oncol
|
2013
|
0.81
|
72
|
Prognostic and predictive value of Phospho-p44/42 and pAKT in HER2-positive locally advanced breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy.
|
World J Surg Oncol
|
2013
|
0.81
|
73
|
Adjuvant therapy of breast cancer with pirarubicin versus epirubicin in combination with cyclophosphamide and 5-fluorouracil.
|
Breast J
|
2011
|
0.81
|
74
|
Efficacy and safety of docetaxel combined with oxaliplatin as a neoadjuvant chemotherapy regimen for Chinese triple-negative local advanced breast cancer patients. A prospective, open, and unicentric Phase II clinical trial.
|
Am J Clin Oncol
|
2013
|
0.80
|
75
|
[BRCA1/2 gene mutation in Chinese familial breast cancer patients: a multi-center report of 115 cases].
|
Zhonghua Yi Xue Za Zhi
|
2008
|
0.80
|
76
|
COX-2 promotes breast cancer cell radioresistance via p38/MAPK-mediated cellular anti-apoptosis and invasiveness.
|
Tumour Biol
|
2013
|
0.80
|
77
|
Nrf2 is associated with the regulation of basal transcription activity of the BRCA1 gene.
|
Acta Biochim Biophys Sin (Shanghai)
|
2013
|
0.80
|
78
|
Differential high-resolution melting analysis for the detection of K-ras codons 12 and 13 mutations in pancreatic cancer.
|
Pancreas
|
2011
|
0.80
|
79
|
Influence of a family history of breast and/or ovarian cancer on breast cancer outcomes.
|
Exp Ther Med
|
2011
|
0.79
|
80
|
Breast conservative therapy in east part of China: a retrospective cohort study.
|
J Cancer Res Clin Oncol
|
2006
|
0.79
|
81
|
Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene.
|
Breast Cancer Res Treat
|
2010
|
0.79
|
82
|
Factors associated with the misdiagnosis of sentinel lymph nodes using touch imprint cytology for early stage breast cancer.
|
Oncol Lett
|
2011
|
0.79
|
83
|
[5589del8: the recurrent mutation of BRCA1 gene in Chinese breast cancer patients].
|
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
|
2007
|
0.79
|
84
|
Predicting sentinel lymph node metastasis in a Chinese breast cancer population: assessment of an existing nomogram and a new predictive nomogram.
|
Breast Cancer Res Treat
|
2012
|
0.79
|
85
|
Using peripheral blood mRNA signature to distinguish between breast cancer and benign breast disease in non-conclusive mammography patients.
|
Cancer Biol Ther
|
2010
|
0.78
|
86
|
Risk factors for postoperative seromas in Chinese breast cancer patients.
|
Chin Med J (Engl)
|
2011
|
0.78
|
87
|
Elevated PIVKA-II is associated with early recurrence and poor prognosis in BCLC 0-A hepatocellular carcinomas.
|
Asian Pac J Cancer Prev
|
2014
|
0.78
|
88
|
[A study of the combination of vinorelbine and epirubicin as neoadjuvant chemotherapy regimen in the treatment of locally advanced breast cancer].
|
Zhonghua Wai Ke Za Zhi
|
2006
|
0.78
|
89
|
Neoadjuvant chemotherapy with vinorelbine-containing regimens in elderly patients with locally advanced breast cancer.
|
Anticancer Res
|
2008
|
0.78
|
90
|
Utility of one-step nucleic acid amplification (OSNA) assay in detecting breast cancer metastases of sentinel lymph nodes in a Chinese population.
|
Breast Cancer
|
2013
|
0.78
|
91
|
Proteomic analysis of the cerebrospinal fluid in multiple sclerosis and neuromyelitis optica patients.
|
Mol Med Rep
|
2012
|
0.78
|
92
|
Surgical management of breast cancer in China: A 15-year single-center retrospective study of 18,502 patients.
|
Medicine (Baltimore)
|
2016
|
0.77
|
93
|
[Peripheral blood mutated p53 DNA and its clinical value in human breast cancer].
|
Zhonghua Zhong Liu Za Zhi
|
2003
|
0.77
|
94
|
Localization and evaluation of sentinel lymph node in breast cancer from computed tomographic lymphography.
|
J Comput Assist Tomogr
|
2011
|
0.77
|
95
|
[Surgical management of early breast cancer].
|
Zhonghua Zhong Liu Za Zhi
|
2007
|
0.77
|
96
|
PEA3 activates CXCR4 transcription in MDA-MB-231 and MCF7 breast cancer cells.
|
Acta Biochim Biophys Sin (Shanghai)
|
2011
|
0.77
|
97
|
The evaluation and optimization of intraoperative touch imprint cytology for sentinel lymph nodes in early-stage breast cancer in China.
|
World J Surg
|
2010
|
0.76
|
98
|
[Retrospective analysis of trastuzumab treatment in 141 patients with Her-2 positive breast cancer].
|
Zhonghua Zhong Liu Za Zhi
|
2010
|
0.76
|
99
|
[Analysis of BRCA1 mutations in Chinese patients with early onset breast cancer and affected relatives].
|
Zhonghua Zhong Liu Za Zhi
|
2004
|
0.76
|
100
|
Clinical significance of aromatase protein expression in axillary node negative breast cancer.
|
J Cancer Res Clin Oncol
|
2007
|
0.76
|
101
|
[Mucosa advancement flap anoplasty in treatment of chronic anal fissures: a prospective, multicenter, randomized controlled trial].
|
Zhong Xi Yi Jie He Xue Bao
|
2011
|
0.76
|
102
|
Association of HER-2 copy number and HER-2/CEP-17 ratio with neoadjuvant taxane-containing chemotherapy sensitivity in locally advanced breast cancer.
|
Oncologist
|
2012
|
0.75
|
103
|
Trastuzumab improves locoregional control in HER2-positive breast cancer patients following adjuvant radiotherapy.
|
Medicine (Baltimore)
|
2016
|
0.75
|
104
|
Determination of carbohydrate-deficient transferrin in a Han Chinese population.
|
BMC Biochem
|
2014
|
0.75
|
105
|
Breast Sclerosing Adenosis and Accompanying Malignancies: A Clinicopathological and Imaging Study in a Chinese Population.
|
Medicine (Baltimore)
|
2015
|
0.75
|
106
|
Clinicopathological features of breast cancer patients with nipple discharge.
|
Mol Med Rep
|
2010
|
0.75
|
107
|
[Application of methylene blue dye to sentinel lymph node biopsy in breast cancer and its influencing factors].
|
Ai Zheng
|
2007
|
0.75
|
108
|
[Biological significance of E-cadherin in an inflammatory breast carcinoma cell line].
|
Zhonghua Zhong Liu Za Zhi
|
2006
|
0.75
|
109
|
[Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine].
|
Zhonghua Zhong Liu Za Zhi
|
2006
|
0.75
|
110
|
[Clinico-pathological features of ER+/PR+ and ER+/PR- breast tumors: a comparative study of 5211 cases].
|
Zhonghua Yi Xue Za Zhi
|
2007
|
0.75
|
111
|
Serum Tumor Marker Levels might have Little Significance in Evaluating Neoadjuvant Treatment Response in Locally Advanced Breast Cancer.
|
Asian Pac J Cancer Prev
|
2015
|
0.75
|
112
|
Unlabeled-probe high-resolution melting to detect KRAS codon 12 and 13 mutations in pancreatic adenocarcinoma tissues.
|
Clin Chem Lab Med
|
2012
|
0.75
|
113
|
[Evaluation of intraoperative molecular assay in sentinel lymph node biopsy from breast cancer patients].
|
Zhonghua Bing Li Xue Za Zhi
|
2010
|
0.75
|
114
|
[Lymphoscintigraphy in sentinel lymph node biopsy of breast cancer].
|
Zhonghua Zhong Liu Za Zhi
|
2002
|
0.75
|
115
|
A novel technique for localization of sentinel lymph node in breast cancer patients based on computed tomographic lymphography.
|
Breast J
|
2011
|
0.75
|
116
|
[Germline mutations of TP53 gene among Chinese families with high risk for breast cancer].
|
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
|
2015
|
0.75
|
117
|
[Clinicopathological significance of aromatase expression in breast cancers].
|
Zhonghua Wai Ke Za Zhi
|
2006
|
0.75
|
118
|
Gene expression profiling in apoptotic k562 cells treated by homoharringtonine.
|
Acta Biochim Biophys Sin (Shanghai)
|
2007
|
0.75
|
119
|
[Intra-operative GeneSearch(TM) BLN assay for detecting breast cancer metastases in sentinel lymph nodes].
|
Zhonghua Yi Xue Za Zhi
|
2011
|
0.75
|
120
|
Dynamic change of the systemic immune inflammation index predicts the prognosis of patients with hepatocellular carcinoma after curative resection.
|
Clin Chem Lab Med
|
2016
|
0.75
|
121
|
A prospective comparison of molecular assay and touch imprint cytology for intraoperative evaluation of sentinel lymph nodes.
|
Chin Med J (Engl)
|
2011
|
0.75
|
122
|
[Study on predictors of long term results for neo-adjuvant chemotherapy in locally advanced breast cancer].
|
Zhonghua Wai Ke Za Zhi
|
2009
|
0.75
|
123
|
[In vitro study of the effects of estrogen receptor beta expression on the biological behavior of a human breast cancer cell line].
|
Zhonghua Zhong Liu Za Zhi
|
2005
|
0.75
|
124
|
Genetic contribution of GADD45A to susceptibility to sporadic and non-BRCA1/2 familial breast cancers: a systematic evaluation in Chinese populations.
|
Breast Cancer Res Treat
|
2009
|
0.75
|
125
|
[Prospective multi-center study of one-step nucleic acid amplification assay for the detection of sentinel lymph nodes metastases in breast cancer patients].
|
Zhonghua Yi Xue Za Zhi
|
2013
|
0.75
|
126
|
[Effect of postoperative pregnancy upon prognosis of young breast cancer patients].
|
Zhonghua Yi Xue Za Zhi
|
2009
|
0.75
|
127
|
GeneSearch™ BLN Assay could replace frozen section and touch imprint cytology for intra-operative assessment of breast sentinel lymph nodes.
|
Breast Cancer
|
2013
|
0.75
|
128
|
[Establishment and clinical application of liquid chromatography-tandem mass spectrometric method for simultaneous determination of plasma 5-fluorouracil].
|
Zhonghua Yi Xue Za Zhi
|
2016
|
0.75
|
129
|
[Expression of CK5/6 and CK17 and its correlation with prognosis of triple-negative breast cancer patients].
|
Zhonghua Zhong Liu Za Zhi
|
2008
|
0.75
|
130
|
[Evaluation of intraoperative touch imprint cytology of sentinel lymph node for breast cancer].
|
Zhonghua Zhong Liu Za Zhi
|
2007
|
0.75
|
131
|
Gene expression pattern in apoptotic QGY-7703 cells induced by homoharringtonine.
|
Acta Pharmacol Sin
|
2007
|
0.75
|