Published in Arterioscler Thromb Vasc Biol on October 11, 2007
Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circ Res (2009) 3.53
Regulatory mechanisms in vascular calcification. Nat Rev Cardiol (2010) 2.22
Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification. Circ Res (2010) 1.75
Calcific aortic valve stenosis: methods, models, and mechanisms. Circ Res (2011) 1.70
Arterial calcification and bone physiology: role of the bone-vascular axis. Nat Rev Endocrinol (2012) 1.66
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice. J Clin Invest (2013) 1.66
Inflammation and the osteogenic regulation of vascular calcification: a review and perspective. Hypertension (2010) 1.61
Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. Circ Res (2010) 1.58
Targeted reduction of vascular Msx1 and Msx2 mitigates arteriosclerotic calcification and aortic stiffness in LDLR-deficient mice fed diabetogenic diets. Diabetes (2014) 1.58
Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes. J Clin Endocrinol Metab (2012) 1.52
Current usage and future directions for the bovine pericardial patch. Ann Vasc Surg (2011) 1.45
Cholecalciferol supplementation alters calcitriol-responsive monocyte proteins and decreases inflammatory cytokines in ESRD. J Am Soc Nephrol (2009) 1.45
Msx2 exerts bone anabolism via canonical Wnt signaling. J Biol Chem (2008) 1.43
Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PLoS One (2015) 1.43
The Wnt signaling pathway: aging gracefully as a protectionist? Pharmacol Ther (2008) 1.38
The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res (2011) 1.29
Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis. Circ Res (2010) 1.29
High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2. Arterioscler Thromb Vasc Biol (2008) 1.20
Mutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome. Am J Hum Genet (2015) 1.17
Molecular and cellular aspects of calcific aortic valve disease. Circ Res (2013) 1.12
Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet (2011) 1.11
Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification. Biochem Biophys Res Commun (2011) 1.09
Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells. Arterioscler Thromb Vasc Biol (2013) 1.08
(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis. Arthritis Res Ther (2011) 1.07
Vascular calcification: pathophysiology and risk factors. Curr Hypertens Rep (2012) 1.06
MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms. Circ Res (2013) 1.02
Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. Antioxid Redox Signal (2009) 1.02
Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus. Biomed Pharmacother (2008) 1.02
TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts. Endocrinology (2012) 0.99
Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arterioscler Thromb Vasc Biol (2011) 0.99
The dualistic role of vitamin D in vascular calcifications. Kidney Int (2010) 0.98
Vascular smooth muscle cell calcification and SLC20 inorganic phosphate transporters: effects of PDGF, TNF-alpha, and Pi. Pflugers Arch (2009) 0.97
RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α. J Vasc Res (2012) 0.96
Vascular calcification and aortic fibrosis: a bifunctional role for osteopontin in diabetic arteriosclerosis. Arterioscler Thromb Vasc Biol (2011) 0.96
The roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcification. Circ Res (2011) 0.96
PERK-eIF2α-ATF4-CHOP signaling contributes to TNFα-induced vascular calcification. J Am Heart Assoc (2013) 0.94
Mechanisms of arterial calcifications and consequences for cardiovascular function. Kidney Int Suppl (2011) (2013) 0.93
Diabetes mellitus: channeling care through cellular discovery. Curr Neurovasc Res (2010) 0.93
Vascular calcification: Mechanisms of vascular smooth muscle cell calcification. Trends Cardiovasc Med (2014) 0.91
Transglutaminase 2-mediated activation of β-catenin signaling has a critical role in warfarin-induced vascular calcification. Arterioscler Thromb Vasc Biol (2011) 0.91
Oxidation, inflammation, and aortic valve calcification peroxide paves an osteogenic path. J Am Coll Cardiol (2008) 0.90
T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. FEBS Lett (2009) 0.90
Rogue proliferation versus restorative protection: where do we draw the line for Wnt and forkhead signaling? Expert Opin Ther Targets (2008) 0.90
Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin. Arterioscler Thromb Vasc Biol (2009) 0.89
Vascular calcification: it's all the RAGE! Arterioscler Thromb Vasc Biol (2011) 0.89
Arterial calcification is driven by RAGE in Enpp1-/- mice. J Vasc Res (2010) 0.89
Discoidin domain receptor-1 deficiency attenuates atherosclerotic calcification and smooth muscle cell-mediated mineralization. Am J Pathol (2009) 0.89
Vascular calcification and renal bone disorders. ScientificWorldJournal (2014) 0.88
PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification. J Biol Chem (2010) 0.88
Sclerostin and DKK1: new players in renal bone and vascular disease. Kidney Int (2015) 0.87
Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting ankylosis protein homolog expression. Kidney Int (2012) 0.87
Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J Mol Cell Cardiol (2009) 0.87
Ankle-brachial index and bone turnover in patients on dialysis. J Am Soc Nephrol (2014) 0.87
In vitro models of aortic valve calcification: solidifying a system. Cardiovasc Pathol (2014) 0.86
An autonomous BMP2 regulatory element in mesenchymal cells. J Cell Biochem (2011) 0.86
Novel avenues of drug discovery and biomarkers for diabetes mellitus. J Clin Pharmacol (2010) 0.86
The connections between vascular calcification and bone health. Nephrol Dial Transplant (2011) 0.85
Quercetin attenuates warfarin-induced vascular calcification in vitro independently from matrix Gla protein. J Biol Chem (2012) 0.84
Cellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its Comorbidities. Front Immunol (2015) 0.84
Regulatory circuits controlling vascular cell calcification. Cell Mol Life Sci (2012) 0.83
Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids. J Lipid Res (2009) 0.83
Wound healing in development. Birth Defects Res C Embryo Today (2012) 0.83
TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin. Open Biol (2016) 0.82
Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification. J Cell Biochem (2015) 0.81
Pathophysiology of the chronic kidney disease-mineral bone disorder. Curr Opin Nephrol Hypertens (2015) 0.80
QCT Volumetric Bone Mineral Density and Vascular and Valvular Calcification: The Framingham Study. J Bone Miner Res (2015) 0.80
Vascular Calcification and Stone Disease: A New Look towards the Mechanism. J Cardiovasc Dev Dis (2015) 0.80
Cell-matrix mechanics and pattern formation in inflammatory cardiovascular calcification. Heart (2016) 0.80
Mechanisms linking osteoporosis with cardiovascular calcification. Curr Osteoporos Rep (2009) 0.79
Policosanol as a new inhibitor candidate for vascular calcification in diabetic hyperlipidemic rats. Exp Biol Med (Maywood) (2016) 0.79
TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB. Cell Death Dis (2016) 0.78
Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation. J Mol Cell Cardiol (2016) 0.78
Innate and Adaptive Immunity in Calcific Aortic Valve Disease. J Immunol Res (2015) 0.78
Medial and intimal calcification in chronic kidney disease: stressing the contributions. J Am Heart Assoc (2013) 0.76
Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis. Am J Pathol (2016) 0.76
The hemosteoblast: friend or foe? Circ Res (2011) 0.76
Bidirectional Translation in Cardiovascular Calcification. Arterioscler Thromb Vasc Biol (2016) 0.75
AGE/RAGE promotes thecalcification of human aortic smooth muscle cells via the Wnt/β-catenin axis. Am J Transl Res (2016) 0.75
COMP-lex Mechanics: Matricrine Signaling. Circ Res (2016) 0.75
"Osteotropic" Wnt/LRP Signals: High-Wire Artists in a Balancing Act Regulating Aortic Structure and Function. Arterioscler Thromb Vasc Biol (2017) 0.75
Macrophage glucocorticoid receptors join the intercellular dialogue in atherosclerotic lesion calcification. Arterioscler Thromb Vasc Biol (2008) 0.75
The Effect of Dantonic Pill on β -Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy. J Diabetes Res (2013) 0.75
Inflammation and the bone-vascular axis in end-stage renal disease. Osteoporos Int (2015) 0.75
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production. Arterioscler Thromb Vasc Biol (2016) 0.75
Animal Models to Study Links between Cardiovascular Disease and Renal Failure and Their Relevance to Human Pathology. Front Immunol (2015) 0.75
Arterial Calcification in Diabetes Mellitus: Preclinical Models and Translational Implications. Arterioscler Thromb Vasc Biol (2016) 0.75
Imaging Atherosclerotic Plaque Calcification: Translating Biology. Curr Atheroscler Rep (2016) 0.75
Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease. Kidney Int (2016) 0.75
The emerging role of interleukin-37 in cardiovascular diseases. Immun Inflamm Dis (2017) 0.75
RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome. Front Genet (2017) 0.75
Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice. J Cell Biochem (2017) 0.75
A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol (2008) 6.90
Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell (2008) 5.04
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development (2003) 4.63
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Cell Stem Cell (2008) 3.15
Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals. J Clin Invest (2005) 3.00
MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem (2003) 2.78
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res (2009) 2.74
Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection. Circulation (2011) 2.60
Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol (2006) 2.28
Smooth muscle cell plasticity: fact or fiction? Circ Res (2012) 2.18
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab (2004) 2.14
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J Biol Chem (2006) 1.99
Prevalence of ideal cardiovascular health and its relationship with the 4-year cardiovascular events in a northern Chinese industrial city. Circ Cardiovasc Qual Outcomes (2012) 1.93
An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circ Res (2006) 1.88
1,25-Dihydroxyvitamin D3 but not cinacalcet HCl (Sensipar/Mimpara) treatment mediates aortic calcification in a rat model of secondary hyperparathyroidism. Nephrol Dial Transplant (2005) 1.76
Noggin and bFGF cooperate to maintain the pluripotency of human embryonic stem cells in the absence of feeder layers. Biochem Biophys Res Commun (2005) 1.74
Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling. J Mol Med (Berl) (2008) 1.72
Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation. J Cell Biochem (2005) 1.69
Arterial calcification and bone physiology: role of the bone-vascular axis. Nat Rev Endocrinol (2012) 1.66
Quantifiable effects of osteopathic manipulative techniques on patients with chronic asthma. J Am Osteopath Assoc (2002) 1.65
Resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction. Cardiovasc Drugs Ther (2008) 1.63
Inflammation and the osteogenic regulation of vascular calcification: a review and perspective. Hypertension (2010) 1.61
Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms. Dev Biol (2006) 1.55
Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters. J Biol Chem (2003) 1.50
Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis. J Cell Sci (2004) 1.49
Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species. Genome Res (2005) 1.48
Deep sequencing of chicken microRNAs. BMC Genomics (2008) 1.48
Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells. J Biol Chem (2002) 1.48
Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development (2002) 1.46
Msx2 exerts bone anabolism via canonical Wnt signaling. J Biol Chem (2008) 1.43
A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. Biochem Biophys Res Commun (2006) 1.41
Teriparatide (human parathyroid hormone (1-34)) inhibits osteogenic vascular calcification in diabetic low density lipoprotein receptor-deficient mice. J Biol Chem (2003) 1.40
Vascular Bmp Msx2 Wnt signaling and oxidative stress in arterial calcification. Ann N Y Acad Sci (2007) 1.37
Sequence conservation and differential expression of Marek's disease virus microRNAs. J Virol (2008) 1.34
Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways. Circ Res (2005) 1.34
Derivation and characterization of hepatic progenitor cells from human embryonic stem cells. PLoS One (2009) 1.33
Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res (2009) 1.31
Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. J Biol Chem (2002) 1.30
Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese: two independent case-control studies. PLoS One (2011) 1.29
The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res (2011) 1.29
Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis. Circ Res (2010) 1.29
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci (2009) 1.27
JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatology (2012) 1.25
Placenta growth factor is over-expressed and has prognostic value in human breast cancer. Eur J Cancer (2005) 1.24
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. Am J Pathol (2009) 1.18
Alphavbeta integrins play an essential role in BMP-2 induction of osteoblast differentiation. J Bone Miner Res (2004) 1.18
A randomized controlled trial testing the efficacy of an HIV/AIDS symptom management manual. J Pain Symptom Manage (2008) 1.16
Osteopontin transcription in aortic vascular smooth muscle cells is controlled by glucose-regulated upstream stimulatory factor and activator protein-1 activities. J Biol Chem (2002) 1.14
MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element. J Biol Chem (2004) 1.13
Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells. Arterioscler Thromb Vasc Biol (2013) 1.08
Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells. J Biol Chem (2003) 1.07
A role for notch signaling in human corneal epithelial cell differentiation and proliferation. Invest Ophthalmol Vis Sci (2007) 1.06
ALDH2 protects against stroke by clearing 4-HNE. Cell Res (2013) 1.05
Accentuated ovariectomy-induced bone loss and altered osteogenesis in heterozygous N-cadherin null mice. J Bone Miner Res (2006) 1.05
Influence of dexamethasone on inflammatory mediators and NF-kappaB expression in multiple organs of rats with severe acute pancreatitis. World J Gastroenterol (2007) 1.04
Effect of organic acids on the growth and lipid accumulation of oleaginous yeast Trichosporon fermentans. Biotechnol Biofuels (2012) 1.03
Autophagy in the retina: a potential role in age-related macular degeneration. Adv Exp Med Biol (2012) 1.02
Osteogenic regulation of vascular calcification. Ann N Y Acad Sci (2006) 1.02
De novo lipogenesis maintains vascular homeostasis through endothelial nitric-oxide synthase (eNOS) palmitoylation. J Biol Chem (2010) 1.02
Cross-species de novo identification of cis-regulatory modules with GibbsModule: application to gene regulation in embryonic stem cells. Genome Res (2008) 1.02
Evaluation of the flocculation performance of carboxymethyl chitosan-graft-polyacrylamide, a novel amphoteric chemically bonded composite flocculant. Water Res (2011) 1.01
Serum microRNA-21 levels are related to tumor size in gastric cancer patients but cannot predict prognosis. Oncol Lett (2013) 1.00
Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor. Development (2003) 1.00
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase). Invest Ophthalmol Vis Sci (2011) 1.00
gamma-Secretase: a multifaceted regulator of angiogenesis. J Cell Mol Med (2008) 0.99
The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium. PLoS One (2012) 0.99
TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts. Endocrinology (2012) 0.99
Expression of placenta growth factor is regulated by both VEGF and hyperglycaemia via VEGFR-2. Microvasc Res (2004) 0.99
Use of magnetic stimulation to elicit motor evoked potentials, somatosensory evoked potentials, and H-reflexes in non-sedated rodents. J Neurosci Methods (2007) 0.97
Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness. J Am Soc Echocardiogr (2008) 0.97
Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells. J Comp Neurol (2003) 0.97
Heterogeneous nuclear ribonucleoprotein K represses transcription from a cytosine/thymidine-rich element in the osteocalcin promoter. Biochem J (2005) 0.97