Published in Curr Opin Struct Biol on October 22, 2007
DSB proteins and bacterial pathogenicity. Nat Rev Microbiol (2009) 1.99
An atlas of the thioredoxin fold class reveals the complexity of function-enabling adaptations. PLoS Comput Biol (2009) 1.26
Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue. J Biol Chem (2009) 1.05
Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB. EMBO J (2009) 1.03
Characterization of two homologous disulfide bond systems involved in virulence factor biogenesis in uropathogenic Escherichia coli CFT073. J Bacteriol (2009) 1.00
Oxidation state-dependent protein-protein interactions in disulfide cascades. J Biol Chem (2011) 0.87
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli. Microb Cell Fact (2013) 0.86
Applications of thiol-disulfide oxidoreductases for optimized in vivo production of functionally active proteins in Bacillus. Appl Microbiol Biotechnol (2009) 0.84
Unraveling the redox properties of the global regulator FurA from Anabaena sp. PCC 7120: disulfide reductase activity based on its CXXC motifs. Antioxid Redox Signal (2014) 0.79
Cellular disulfide bond formation in bioactive peptides and proteins. Int J Mol Sci (2015) 0.78
An extended active-site motif controls the reactivity of the thioredoxin fold. J Biol Chem (2014) 0.77
Evidence for the validity of a sleep habits survey for adolescents. Sleep (2003) 3.46
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers. Brain Behav Immun (2009) 3.00
Post-crystallization treatments for improving diffraction quality of protein crystals. Acta Crystallogr D Biol Crystallogr (2005) 2.62
Human sulfotransferases and their role in chemical metabolism. Toxicol Sci (2005) 2.27
Protein disulfide isomerase: the structure of oxidative folding. Trends Biochem Sci (2006) 1.99
DSB proteins and bacterial pathogenicity. Nat Rev Microbiol (2009) 1.99
Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking. Traffic (2006) 1.88
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins. Proc Natl Acad Sci U S A (2007) 1.79
The sigmoidally transformed cosine curve: a mathematical model for circadian rhythms with symmetric non-sinusoidal shapes. Stat Med (2006) 1.68
In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling. Mol Microbiol (2009) 1.62
Dehydration converts DsbG crystal diffraction from low to high resolution. Structure (2003) 1.60
Effect of light treatment on sleep and circadian rhythms in demented nursing home patients. J Am Geriatr Soc (2002) 1.53
Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement (2013) 1.51
Age and sleep disturbances among American men and women: data from the U.S. Behavioral Risk Factor Surveillance System. Sleep (2012) 1.49
Increased light exposure consolidates sleep and strengthens circadian rhythms in severe Alzheimer's disease patients. Behav Sleep Med (2003) 1.47
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition. J Biol Chem (2002) 1.42
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proc Natl Acad Sci U S A (2011) 1.38
Federated repositories of X-ray diffraction images. Acta Crystallogr D Biol Crystallogr (2008) 1.33
Randomized, controlled trial of a nonpharmacological intervention to improve abnormal sleep/wake patterns in nursing home residents. J Am Geriatr Soc (2005) 1.23
Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation. Proc Natl Acad Sci U S A (2010) 1.22
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation. Proc Natl Acad Sci U S A (2007) 1.20
Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide. Proc Natl Acad Sci U S A (2004) 1.16
Structure and function of DsbA, a key bacterial oxidative folding catalyst. Antioxid Redox Signal (2011) 1.14
Improved success of sparse matrix protein crystallization screening with heterogeneous nucleating agents. PLoS One (2007) 1.12
An inflammatory role for the mammalian carboxypeptidase inhibitor latexin: relationship to cystatins and the tumor suppressor TIG1. Structure (2005) 1.11
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins. Proc Natl Acad Sci U S A (2013) 1.10
Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation. J Mol Biol (2008) 1.10
More daytime sleeping predicts less functional recovery among older people undergoing inpatient post-acute rehabilitation. Sleep (2008) 1.10
Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease. Am J Geriatr Psychiatry (2009) 1.09
Complement protein C3 binding to Mycobacterium tuberculosis is initiated by the classical pathway in human bronchoalveolar lavage fluid. Infect Immun (2004) 1.09
Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide. Proc Natl Acad Sci U S A (2012) 1.08
The role of the user within the medical device design and development process: medical device manufacturers' perspectives. BMC Med Inform Decis Mak (2011) 1.07
Insomnia and daytime napping in older adults. J Clin Sleep Med (2006) 1.06
The structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates. J Biol Chem (2005) 1.06
Properties of the thioredoxin fold superfamily are modulated by a single amino acid residue. J Biol Chem (2009) 1.05
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. J Biol Chem (2009) 1.05
Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3. J Biol Chem (2004) 1.05
Structure of CcmG/DsbE at 1.14 A resolution: high-fidelity reducing activity in an indiscriminately oxidizing environment. Structure (2002) 1.05
The timing of activity rhythms in patients with dementia is related to survival. J Gerontol A Biol Sci Med Sci (2004) 1.05
Human cytosolic sulfotransferase SULT1A1. Int J Biochem Cell Biol (2006) 1.04
Staphylococcus aureus DsbA does not have a destabilizing disulfide. A new paradigm for bacterial oxidative folding. J Biol Chem (2007) 1.04
Crystallography and protein-protein interactions: biological interfaces and crystal contacts. Biochem Soc Trans (2008) 1.03
The SBSM Guide to Actigraphy Monitoring: Clinical and Research Applications. Behav Sleep Med (2015) 1.02
Surfactant protein D increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infect Immun (2006) 1.01
D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. Chembiochem (2003) 0.99
Cortactin adopts a globular conformation and bundles actin into sheets. J Biol Chem (2008) 0.98
Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. J Am Chem Soc (2010) 0.98
Targeting virulence not viability in the search for future antibacterials. Br J Clin Pharmacol (2015) 0.96
Laboratory evolution of one disulfide isomerase to resemble another. Proc Natl Acad Sci U S A (2007) 0.95
Comparison of three commercial sparse-matrix crystallization screens. Acta Crystallogr D Biol Crystallogr (2003) 0.95
Effects of a late-life suicide risk--assessment training on multidisciplinary healthcare providers. J Am Geriatr Soc (2012) 0.95
Sleep-disordered breathing and agitation in institutionalized adults with Alzheimer disease. Am J Geriatr Psychiatry (2003) 0.94
The relationship between dementia severity and rest/activity circadian rhythms. Neuropsychiatr Dis Treat (2005) 0.94
Effect of light on agitation in institutionalized patients with severe Alzheimer disease. Am J Geriatr Psychiatry (2003) 0.94
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase. J Med Chem (2005) 0.93
Depression in older patients admitted for postacute nursing home rehabilitation. J Am Geriatr Soc (2005) 0.93
United we stand: combining structural methods. Curr Opin Struct Biol (2008) 0.92
User needs elicitation via analytic hierarchy process (AHP). A case study on a Computed Tomography (CT) scanner. BMC Med Inform Decis Mak (2013) 0.92
Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. J Med Chem (2004) 0.90
Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo. Antioxid Redox Signal (2013) 0.90
Characterization of the DsbA oxidative folding catalyst from Pseudomonas aeruginosa reveals a highly oxidizing protein that binds small molecules. Antioxid Redox Signal (2010) 0.90
Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4. Protein Expr Purif (2003) 0.90
Disrupting life events and the sleep-wake cycle in depression. Psychol Med (2006) 0.89
Structural and functional characterization of the oxidoreductase alpha-DsbA1 from Wolbachia pipientis. Antioxid Redox Signal (2009) 0.89
Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry (2005) 0.89
Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking. Protein Eng Des Sel (2005) 0.89
Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase. J Med Chem (2004) 0.88
Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases. Acta Crystallogr D Biol Crystallogr (2013) 0.88
Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.87
Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. J Biol Chem (2013) 0.87
Use of the Breathlessness, Cough, and Sputum Scale (BCSS(©)) in Pulmonary Rehabilitation. Open Respir Med J (2013) 0.87
Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem J (2009) 0.86
The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane. J Cell Sci (2013) 0.86
Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase. Protein Sci (2002) 0.86
Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem J (2010) 0.86
Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. J Biol Chem (2010) 0.85
Planktonic microbes in the Gulf of Maine area. PLoS One (2011) 0.85
Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling. Methods Mol Biol (2008) 0.85
A method for screening the temperature dependence of three-dimensional crystal formation. Acta Crystallogr D Biol Crystallogr (2006) 0.84
Crystal structures of highly constrained substrate and hydrolysis products bound to HIV-1 protease. Implications for the catalytic mechanism. Biochemistry (2008) 0.84
The Arabidopsis B3 domain protein VERNALIZATION1 (VRN1) is involved in processes essential for development, with structural and mutational studies revealing its DNA-binding surface. J Biol Chem (2012) 0.84
Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem (2007) 0.84
The association between difficulty using positive airway pressure equipment and adherence to therapy: a pilot study. Sleep Breath (2012) 0.83
The effect of design on the usability and real world effectiveness of medical devices: a case study with adolescent users. Appl Ergon (2013) 0.83
Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA. Angew Chem Int Ed Engl (2014) 0.83
Incorporating a TEV cleavage site reduces the solubility of nine recombinant mouse proteins. Protein Expr Purif (2006) 0.83
The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production. Acta Crystallogr D Biol Crystallogr (2012) 0.83
Crystallization of the C-terminal domain of the mouse brain cytosolic long-chain acyl-CoA thioesterase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.83
Awake at 4 AM: treatment of insomnia with early morning awakenings among older adults. J Clin Psychol (2010) 0.82
Microbial community diversity in the phycosphere of natural populations of the toxic alga, Alexandrium fundyense. Environ Microbiol (2007) 0.82
The role of the synergistic phosphate anion in iron transport by the periplasmic iron-binding protein from Haemophilus influenzae. Biochem J (2007) 0.81
An automatable screen for the rapid identification of proteins amenable to refolding. Proteomics (2006) 0.81
Comparison of the binding of 3-fluoromethyl-7-sulfonyl-1,2,3,4-tetrahydroisoquinolines with their isosteric sulfonamides to the active site of phenylethanolamine N-methyltransferase. J Med Chem (2006) 0.81