Published in Ann N Y Acad Sci on September 01, 2007
Treatment of traumatic brain injury with thymosin β₄ in rats. J Neurosurg (2010) 0.96
Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain injury in rats. J Neurosurg (2012) 0.91
Exogenous thymosin beta4 prevents apoptosis in human intervertebral annulus cells in vitro. Biotech Histochem (2009) 0.81
Cardioprotection by systemic dosing of thymosin beta four following ischemic myocardial injury. Front Pharmacol (2013) 0.81
Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells. PLoS One (2016) 0.79
LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway. Stem Cell Res Ther (2016) 0.78
Potential role of thymosin Beta 4 in liver fibrosis. Int J Mol Sci (2015) 0.77
Verifiable hypotheses for thymosin β4-dependent and -independent angiogenic induction of Trichinella spiralis-triggered nurse cell formation. Int J Mol Sci (2013) 0.77
Thymosin Beta-4 Induces Mouse Hair Growth. PLoS One (2015) 0.76
Association between serum thymosin β4 levels of rheumatoid arthritis patients and disease activity and response to therapy. Clin Rheumatol (2012) 0.76
Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence. Chin Med J (Engl) (2015) 0.75
Recombinant adeno-associated virus carrying thymosin β4 suppresses experimental colitis in mice. World J Gastroenterol (2017) 0.75
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis. Int J Biochem Cell Biol (2006) 3.24
In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract. Nat Protoc (2010) 2.71
The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art. Angiogenesis (2009) 2.67
The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitro. Int J Cancer (2002) 2.56
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. J Natl Cancer Inst (2004) 2.52
Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst (2003) 2.23
Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures. Muscle Nerve (2009) 2.19
Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Cancer Res (2002) 1.73
The basement membrane matrix in malignancy. J Pathol (2003) 1.69
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior. FASEB J (2004) 1.64
Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms. Development (2002) 1.62
Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development. Semin Cancer Biol (2002) 1.57
Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. Trends Mol Med (2005) 1.56
Significance of heparanase in cancer and inflammation. Cancer Microenviron (2011) 1.46
Heparanase promotes growth, angiogenesis and survival of primary breast tumors. Int J Cancer (2006) 1.42
Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation. Stem Cells (2007) 1.41
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development (2007) 1.40
Role of endothelial heparanase in delayed-type hypersensitivity. Blood (2005) 1.35
Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors. FASEB J (2006) 1.33
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice. J Clin Invest (2011) 1.32
Complex extracellular matrices promote tissue-specific stem cell differentiation. Stem Cells (2005) 1.31
Estrogens and the vascular endothelium. Ann N Y Acad Sci (2002) 1.31
Heparanase: one molecule with multiple functions in cancer progression. Connect Tissue Res (2008) 1.29
Heparanase is essential for the development of diabetic nephropathy in mice. Diabetes (2011) 1.29
Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells. Int J Cancer (2011) 1.29
The effects of adrenomedullin overexpression in breast tumor cells. J Natl Cancer Inst (2002) 1.26
Function of heparanase in prostate tumorigenesis: potential for therapy. Clin Cancer Res (2008) 1.25
The actin binding site on thymosin beta4 promotes angiogenesis. FASEB J (2003) 1.24
An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst (2004) 1.24
Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis. Cancer Res (2005) 1.16
Thymosin beta4 increases hair growth by activation of hair follicle stem cells. FASEB J (2003) 1.10
Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy. PLoS One (2010) 1.09
Regulation of heparanase gene expression by estrogen in breast cancer. Cancer Res (2003) 1.09
Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther (2011) 1.07
Antimetastatic activity of insulin-like growth factor binding protein-3 in lung cancer is mediated by insulin-like growth factor-independent urokinase-type plasminogen activator inhibition. Mol Cancer Ther (2006) 1.01
Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms. Oncogene (2005) 1.00
Role of heparanase in radiation-enhanced invasiveness of pancreatic carcinoma. Cancer Res (2011) 1.00
Identification of an active site on the laminin alpha5 chain globular domain that binds to CD44 and inhibits malignancy. Cancer Res (2004) 0.98
Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium. Fertil Steril (2002) 0.98
Angiogenic activity of human CC chemokine CCL15 in vitro and in vivo. FEBS Lett (2004) 0.98
Heparanase regulates murine hair growth. Am J Pathol (2005) 0.97
Alteration of helper T-cell related cytokine production in splenocytes during Trichinella spiralis infection. Vet Parasitol (2011) 0.97
Pericyte-like location of GFP-tagged melanoma cells: ex vivo and in vivo studies of extravascular migratory metastasis. Am J Pathol (2004) 0.97
Matrix cell adhesion activation by non-adhesion proteins. J Cell Sci (2005) 0.95
Oxidative stress in pregnant women and birth weight reduction. Reprod Toxicol (2005) 0.95
Haplotype analysis of the matrix metalloproteinase-9 gene associated with advanced-stage endometriosis. Fertil Steril (2008) 0.94
Biological activities of homologous loop regions in the laminin alpha chain G domains. J Biol Chem (2003) 0.93
Impact of heparanase and the tumor microenvironment on cancer metastasis and angiogenesis: basic aspects and clinical applications. Rambam Maimonides Med J (2011) 0.92
Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection. Nat Protoc (2012) 0.92
Tamoxifen induces heparanase expression in estrogen receptor-positive breast cancer. Clin Cancer Res (2007) 0.92
Angiogenic laminin-derived peptides stimulate wound healing. Int J Biochem Cell Biol (2008) 0.91
Thymosin beta 4 stimulates laminin-5 production independent of TGF-beta. Exp Cell Res (2004) 0.90
New method for modeling connective-tissue cell migration: improved accuracy on motility parameters. Biophys J (2007) 0.90
Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice. Wound Repair Regen (2003) 0.90
Angiotropism, pericytic mimicry and extravascular migratory metastasis in melanoma: an alternative to intravascular cancer dissemination. Cancer Microenviron (2014) 0.90
Heparanase in inflammation and inflammation-associated cancer. FEBS J (2013) 0.90
Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse. PLoS One (2010) 0.90
Pilot study on "pericytic mimicry" and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface. Cancer Microenviron (2012) 0.89
Tissue and serum angiogenic activity is associated with low prevalence of ischemic complications in patients with giant-cell arteritis. Circulation (2002) 0.89
The role of thymosin beta 4 on odontogenic differentiation in human dental pulp cells. PLoS One (2013) 0.89
Effects of the GSTM1 and GSTT1 polymorphisms on the relationship between maternal exposure to environmental tobacco smoke and neonatal birth weight. J Occup Environ Med (2003) 0.89
Over-expression of thymosin beta 4 promotes abnormal tooth development and stimulation of hair growth. Int J Dev Biol (2010) 0.89
Thymosin beta4 promotes matrix metalloproteinase expression during wound repair. J Cell Physiol (2006) 0.89
Thymosin β4 induces the expression of vascular endothelial growth factor (VEGF) in a hypoxia-inducible factor (HIF)-1α-dependent manner. Biochim Biophys Acta (2010) 0.88
A case of oral myiasis caused by Lucilia sericata (Diptera: Calliphoridae) in Korea. Korean J Parasitol (2013) 0.88
Pericytic-like angiotropism of glioma and melanoma cells. Am J Dermatopathol (2002) 0.88
Ile-Lys-Val-Ala-Val (IKVAV)-containing laminin alpha1 chain peptides form amyloid-like fibrils. FEBS Lett (2002) 0.88
Laminin alpha5 chain metastasis- and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44. Cancer Res (2005) 0.87
A truncated plasminogen activator inhibitor-1 protein blocks the availability of heparin-binding vascular endothelial growth factor A isoforms. J Biol Chem (2002) 0.87
Identification of a potent peptide antagonist to an active laminin-1 sequence that blocks angiogenesis and tumor growth. Cancer Res (2003) 0.87
Induction of apoptosis by fucoidan in human leukemia U937 cells through activation of p38 MAPK and modulation of Bcl-2 family. Mar Drugs (2013) 0.87
The B16F10 cell receptor for a metastasis-promoting site on laminin-1 is a heparan sulfate/chondroitin sulfate-containing proteoglycan. Cancer Res (2002) 0.87
Thymosin β4 expression in human tissues and in tumors using tissue microarrays. Appl Immunohistochem Mol Morphol (2011) 0.86
Effects of IL-1 molecules on growth patterns of 3-MCA-induced cell lines: an interplay between immunogenicity and invasive potential. J Immunotoxicol (2010) 0.86
Heparanase enzyme in chronic inflammatory bowel disease and colon cancer. Cell Mol Life Sci (2012) 0.85
The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands. J Pathol (2013) 0.85
Overexpression of malignancy-associated laminins and laminin receptors by angiotropic human melanoma cells in a chick chorioallantoic membrane model. J Cutan Pathol (2009) 0.85
Genome-wide analysis of DNA methylation patterns in horse. BMC Genomics (2014) 0.85
Basement membrane matrix (BME) has multiple uses with stem cells. Stem Cell Rev (2012) 0.84
Polymorphisms of the genes encoding the GSTM1, GSTT1 and GSTP1 in Korean women: no association with endometriosis. Mol Hum Reprod (2004) 0.84
Zyxin is upregulated in the nucleus by thymosin beta4 in SiHa cells. Exp Cell Res (2006) 0.84
Elevated expression of thymosin β4, vascular endothelial growth factor (VEGF), and hypoxia inducible factor (HIF)-1α in early-stage cervical cancers. Pathol Oncol Res (2011) 0.84
Cysteine protease inhibitor (AcStefin) is required for complete cyst formation of Acanthamoeba. Eukaryot Cell (2013) 0.84
Integrin-dependent cell behavior on ECM peptide-conjugated chitosan membranes. Biopolymers (2007) 0.83
Covalent surface chemistry gradients for presenting bioactive peptides. Anal Biochem (2007) 0.83
Could pericytic mimicry represent another type of melanoma cell plasticity with embryonic properties? Pigment Cell Melanoma Res (2013) 0.83
Trichinella spiralis infection induces angiogenic factor thymosin β4 expression. Vet Parasitol (2011) 0.83
Identification of redundant angiogenic sites in laminin alpha1 and gamma1 chains. Exp Cell Res (2003) 0.83
Expression patterns of Thymosin β4 and cancer stem cell marker CD133 in ovarian cancers. Pathol Oncol Res (2012) 0.82
Laminin-111-derived peptides and cancer. Cell Adh Migr (2012) 0.82
Human melanoma cell migration along capillary-like structures in vitro: a new dynamic model for studying extravascular migratory metastasis. J Invest Dermatol (2002) 0.81